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Adrenal Venöz Örnekleme; Tek Merkez Deneyimi

Year 2021, Volume: 54 Issue: 3, 387 - 390, 01.01.2022
https://doi.org/10.20492/aeahtd.961378

Abstract

Amaç: Sekonder hipertansiyonun nedenlerinden birisi primer hiperaldosteronizm olup tedavi öncesi altın standart test olan adrenal venöz örnekleme (AVÖ) yapılması önerilmektedir. Çalışmamızın amacı girişimsel rayoloji ünitemizde yapılan AVÖ deneyimimizi sunmaktır.
Gereç ve yöntem: Çalışmaya alınan 19 hastanın 11’i erkek ve 8’i kadın olup yaş ortalaması 50,5 idi. Hastalarda işlem için ana femoral vene giriş yapıldı. Çeşitli kateter manipülasyonları ile inferior vena kava kraniyal kesimine ulaşıldı ve bilateral adrenal ven selektif kateterize edilerek kan örnekleri alındı.
Bulgular: Tüm hastalarda sol adrenal ven kateterizasyonunda başarılı olundu. Selektif sağ adrenal ven kateterizasyonunda %79 başarı oranı sağlandı. Ayrıca 1 hastada sağ adrenal ven duplike olduğu için selektif kateterizasyon sağlanamadı. Sadece 2 hastada femoral ven giriş bölgesinde minimal hematom dışında önemli bir komplikasyon izlenmedi.
Sonuç: AVÖ yapılması zor ama primer hiperaldosteronizm tanısı için ve tedavisinden önce tercih edilmesi gereken bir yöntemdir.

Supporting Institution

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References

  • 1. Funder JW, Carey RM, Mantero F, et al. The management of primary aldosteronism: case detection, diagnosis, and treatment: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016; 101:1889-916.
  • 2. Arlt W. A detour guide to the Endocrine Society Clinical Practice Guideline on case detection, diagnosis and treatment of patients with primaryaldosteronism. Eur J Endocrinol. 2010; 162:435-8.
  • 3. Williams TA, Lenders JWM, Mulatero P, et al. Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort. Lancet Diabetes Endocrinol. 2017; 5:689-99.
  • 4. Omura K, Ota H, Takahashi Y, et al. Anatomical variations of the right adrenal vein. Hypertension. 2017; 69(3):428-34.
  • 5. Daunt N. Adrenal vein sampling: how to make it quick, easy, and successful. Radiographics. 2005; 25:143-58.
  • 6. Vonend O, Ockenfels N, Gao X, et al. Adrenal venous sampling: evaluation of the German Conn’s registry. Hypertension. 2011; 57:990-5.
  • 7. Harvey A, Kline G, Pasieka JL. Adrenal venous sampling in primary hyperaldosteronism: comparison of radiographic with biochemical success and the clinical decision-making with “less than ideal” testing. Surgery. 2006; 140:847-53.
  • 8. Kempers MJ, Lenders JW, van Outheusden L, et al. Systematic review: diagnostic procedures to differentiate unilateral from bilateral adrenal abnormality in primary aldosteronism. Ann Intern Med. 2009; 151:329-37.
  • 9. Nishikawa T, Omura M, Satoh F, et al. Guidelines for the diagnosis and treatment of primary aldosteronism–the Japan Endocrine Society 2009. Endocr J. 2011; 58(9):711-21.
  • 10. Rossi GP, Sacchetto A, Chiesura-Corona M, et al. Identification of the etiology of primary aldosteronism with adrenal vein sampling in patients with equivocal computed tomography and magnetic resonance findings: Results in 104 consecutive cases. J Clin Endocrinol Metab. 2001; 86:1083-90.
  • 11. Rossi GP, Auchus RJ, Brown M, et al. An expert consensus statement on use of adrenal vein sampling for the subtyping of primary aldosteronism. Hypertension. 2014; 63(1):151-60.
  • 12. Monticone S, Satoh F, Dietz AS, et al. Clinical management and outcomes of adrenal hemorrhage following adrenal vein sampling in primary aldosteronism. Hypertension. 2016; 67(1):146-52.
  • 13. Rossi GP, Maiolino G, Seccia TM. Adrenal Venous Sampling: Where Do We Stand? Endocrinol Metab Clin N Am. 2019; 48(4):843-58.
  • 14. Kahn SL, Angle JF. Adrenal vein sampling. Tech Vasc Interv Radiol. 2010; 13(2):110-25.
  • 15. Milliez P, Girerd X, Plouin PF, et al. Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism. J Am Coll Cardiol. 2005; 45(8):1243-8.
  • 16. Reincke M, Fischer E, Gerum S, et al. Observational study mortality in treated primary aldosteronism: the German Conn’s registry. Hypertension. 2012; 60(3):618-24.
  • 17. White ML, Gauger PG, Doherty GM, et al. The role of radiologic studies in the evaluation and management of primary hyperaldosteronism. Surgery. 2008; 144:926-33.
  • 18. Gordon RD. Primary aldosteronism. J Endocrinol Invest. 1995; 18:495-511.
  • 19. Blumenfeld JD, Sealey JE, Schlussel Y, et al. Diagnosis and treatment of primary hyperaldosteronism. Ann Intern Med. 1994; 121:877-85.
  • 20. Stowasser M, Gordon RD, Rutherford JC, et al. Diagnosis and management of primary aldosteronism. J Renin Angiotensin Aldosterone Syst. 2001; 2:156-69.
Year 2021, Volume: 54 Issue: 3, 387 - 390, 01.01.2022
https://doi.org/10.20492/aeahtd.961378

Abstract

References

  • 1. Funder JW, Carey RM, Mantero F, et al. The management of primary aldosteronism: case detection, diagnosis, and treatment: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016; 101:1889-916.
  • 2. Arlt W. A detour guide to the Endocrine Society Clinical Practice Guideline on case detection, diagnosis and treatment of patients with primaryaldosteronism. Eur J Endocrinol. 2010; 162:435-8.
  • 3. Williams TA, Lenders JWM, Mulatero P, et al. Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort. Lancet Diabetes Endocrinol. 2017; 5:689-99.
  • 4. Omura K, Ota H, Takahashi Y, et al. Anatomical variations of the right adrenal vein. Hypertension. 2017; 69(3):428-34.
  • 5. Daunt N. Adrenal vein sampling: how to make it quick, easy, and successful. Radiographics. 2005; 25:143-58.
  • 6. Vonend O, Ockenfels N, Gao X, et al. Adrenal venous sampling: evaluation of the German Conn’s registry. Hypertension. 2011; 57:990-5.
  • 7. Harvey A, Kline G, Pasieka JL. Adrenal venous sampling in primary hyperaldosteronism: comparison of radiographic with biochemical success and the clinical decision-making with “less than ideal” testing. Surgery. 2006; 140:847-53.
  • 8. Kempers MJ, Lenders JW, van Outheusden L, et al. Systematic review: diagnostic procedures to differentiate unilateral from bilateral adrenal abnormality in primary aldosteronism. Ann Intern Med. 2009; 151:329-37.
  • 9. Nishikawa T, Omura M, Satoh F, et al. Guidelines for the diagnosis and treatment of primary aldosteronism–the Japan Endocrine Society 2009. Endocr J. 2011; 58(9):711-21.
  • 10. Rossi GP, Sacchetto A, Chiesura-Corona M, et al. Identification of the etiology of primary aldosteronism with adrenal vein sampling in patients with equivocal computed tomography and magnetic resonance findings: Results in 104 consecutive cases. J Clin Endocrinol Metab. 2001; 86:1083-90.
  • 11. Rossi GP, Auchus RJ, Brown M, et al. An expert consensus statement on use of adrenal vein sampling for the subtyping of primary aldosteronism. Hypertension. 2014; 63(1):151-60.
  • 12. Monticone S, Satoh F, Dietz AS, et al. Clinical management and outcomes of adrenal hemorrhage following adrenal vein sampling in primary aldosteronism. Hypertension. 2016; 67(1):146-52.
  • 13. Rossi GP, Maiolino G, Seccia TM. Adrenal Venous Sampling: Where Do We Stand? Endocrinol Metab Clin N Am. 2019; 48(4):843-58.
  • 14. Kahn SL, Angle JF. Adrenal vein sampling. Tech Vasc Interv Radiol. 2010; 13(2):110-25.
  • 15. Milliez P, Girerd X, Plouin PF, et al. Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism. J Am Coll Cardiol. 2005; 45(8):1243-8.
  • 16. Reincke M, Fischer E, Gerum S, et al. Observational study mortality in treated primary aldosteronism: the German Conn’s registry. Hypertension. 2012; 60(3):618-24.
  • 17. White ML, Gauger PG, Doherty GM, et al. The role of radiologic studies in the evaluation and management of primary hyperaldosteronism. Surgery. 2008; 144:926-33.
  • 18. Gordon RD. Primary aldosteronism. J Endocrinol Invest. 1995; 18:495-511.
  • 19. Blumenfeld JD, Sealey JE, Schlussel Y, et al. Diagnosis and treatment of primary hyperaldosteronism. Ann Intern Med. 1994; 121:877-85.
  • 20. Stowasser M, Gordon RD, Rutherford JC, et al. Diagnosis and management of primary aldosteronism. J Renin Angiotensin Aldosterone Syst. 2001; 2:156-69.
There are 20 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Original research article
Authors

Azad Hekimoğlu 0000-0001-7853-019X

Onur Ergun 0000-0002-0495-0500

Erdem Birgi 0000-0001-7808-7300

Baki Hekimoğlu 0000-0002-1824-5853

Publication Date January 1, 2022
Submission Date July 2, 2021
Published in Issue Year 2021 Volume: 54 Issue: 3

Cite

AMA Hekimoğlu A, Ergun O, Birgi E, Hekimoğlu B. Adrenal Venöz Örnekleme; Tek Merkez Deneyimi. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi. January 2022;54(3):387-390. doi:10.20492/aeahtd.961378