Nijmegen breakage syndrome (NBS) is a rare autosomal recessive chromosomal instability typically characterized by microcephaly, growth retardation, bird-like facial appearance, immunodeficiency, radiation hypersensitivity, and a predisposition to malignancies. Patients with NBS have an increased risk for lymphomas, mainly non-Hodgkin's lymphoma (NHL). Diffuse large B-cell lymphoma is one of the most common type of lymphoma in NBS patients. Prognosis is still poor. Herein, we, for the first time, report NBS in fraternal twins and synchronous development of NHL
Primary Language | English |
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Subjects | Clinical Sciences |
Journal Section | Case Reports |
Authors | |
Publication Date | September 10, 2023 |
Submission Date | January 27, 2023 |
Published in Issue | Year 2023 Volume: 1 Issue: 3 |