Case Report
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Angioedema developing in half of the tongue with captopril.

Year 2020, Volume: 2 Issue: 3, 249 - 251, 15.12.2020

Abstract

Angioedema (AE) is a life-threatening condition that can be seen in hereditary or non-hereditary form, usually manifests in subcutaneous tissue and progressed with edema in the face, lips, tongue, larynx and gastrointestinal system. Captopril is the first generated angiotensin-converting enzyme (ACE) inhibitor. Since the inhibition of ACE and consequently the angiotensin II level in plasma and tissues is reduced and quinine degradation is also inhibited by ACE, the level of bradykinin increases in plasma and tissues. It is thought to that the bradykinin causes edema due to vasodilation and increased vascular permaability. In this case report, we reviewed a 63-year-old patient, who hospitalized in the general surgery ward with the preliminary diagnosis of acute cholecystitis, developed AE after treated with 25 mg captopril for high blood pressure.

Thanks

We would like to thank Assoc. Prof. Şeref Kerem Çorbacıoğlu for her contributions in the preparation process of the article.

References

  • 1- Miller DR, Oliveria SA, Berlowitz DR, Fincke BJ, Stang P, Lillienfeld DE. Angioedema incidence in US veterans initiating angiotensin-converting enzyme inhibitors. Hypertension 2008;51:1624–30
  • 2- Leenan,FHH, Nivachuku CE, Black HR, et al.Clinical events in high risk hypertensive patients randomly assigned to calcium channel blocker versus angiotensin-converting enzyme inhibitor in the antihypertensive and lipid lowering treat-ment to prevent heart attack trial. Hypertension 2006;48:374–84.
  • 3- Inomata N.Recent advances in drug-ınducedangioedema.Allergol Int. 2012;61(4):545-557
  • 4- Lewis LM. Angioedema: etiology, pathophysiology, current and emerging therapies.J Emerg Med.2013;45(5):789-796
  • 5- Kyrmizakis DE, Papadakis CE, Fountoulakis EJ, Liolios AD, Skoulas JG. Tongue angioedema after long-term use of ACE inhibitors. AM J Otolaryngol 1998;19(6):394-6
  • 6- Kaplan AP, Greaves MW. Angioedema. Am Acad Dermatol. 2005;53(3):373-388.
  • 7- Remarks on the work of C. Maier. The risk of postoperative angioedema following the use of ACE antagonists. Anesthesist (1995) 44:875-879]
  • 8- Cupido C, Rayner B. Life-threatening angioedema and death associated with ACE inhibitor enarlapril. S Afr Med J 2007;97:244–45.
  • 9- Dean DE, Schultz DL, Powers RH. Asphyxia due to angiotensin converting enzyme (ACE) inhibitor mediated angioedema of the tongue during treatment of hypertensive heart disease. J Forensic Sci 2001;46:1239–43.
  • 10- Grant NN, Deeb ZE, Chia SH. Clinical experience with angiotensin-convertingenzyme inhibitor-induced angioedema. Otolaryngology Head and Neck Surgery 2007;137(6):931-5
Year 2020, Volume: 2 Issue: 3, 249 - 251, 15.12.2020

Abstract

References

  • 1- Miller DR, Oliveria SA, Berlowitz DR, Fincke BJ, Stang P, Lillienfeld DE. Angioedema incidence in US veterans initiating angiotensin-converting enzyme inhibitors. Hypertension 2008;51:1624–30
  • 2- Leenan,FHH, Nivachuku CE, Black HR, et al.Clinical events in high risk hypertensive patients randomly assigned to calcium channel blocker versus angiotensin-converting enzyme inhibitor in the antihypertensive and lipid lowering treat-ment to prevent heart attack trial. Hypertension 2006;48:374–84.
  • 3- Inomata N.Recent advances in drug-ınducedangioedema.Allergol Int. 2012;61(4):545-557
  • 4- Lewis LM. Angioedema: etiology, pathophysiology, current and emerging therapies.J Emerg Med.2013;45(5):789-796
  • 5- Kyrmizakis DE, Papadakis CE, Fountoulakis EJ, Liolios AD, Skoulas JG. Tongue angioedema after long-term use of ACE inhibitors. AM J Otolaryngol 1998;19(6):394-6
  • 6- Kaplan AP, Greaves MW. Angioedema. Am Acad Dermatol. 2005;53(3):373-388.
  • 7- Remarks on the work of C. Maier. The risk of postoperative angioedema following the use of ACE antagonists. Anesthesist (1995) 44:875-879]
  • 8- Cupido C, Rayner B. Life-threatening angioedema and death associated with ACE inhibitor enarlapril. S Afr Med J 2007;97:244–45.
  • 9- Dean DE, Schultz DL, Powers RH. Asphyxia due to angiotensin converting enzyme (ACE) inhibitor mediated angioedema of the tongue during treatment of hypertensive heart disease. J Forensic Sci 2001;46:1239–43.
  • 10- Grant NN, Deeb ZE, Chia SH. Clinical experience with angiotensin-convertingenzyme inhibitor-induced angioedema. Otolaryngology Head and Neck Surgery 2007;137(6):931-5
There are 10 citations in total.

Details

Primary Language English
Subjects Emergency Medicine
Journal Section Case Reports
Authors

Sedat Akkan 0000-0002-3578-9422

Ömür Uyanık 0000-0001-6500-5812

Publication Date December 15, 2020
Submission Date November 12, 2020
Acceptance Date November 12, 2020
Published in Issue Year 2020 Volume: 2 Issue: 3

Cite

APA Akkan, S., & Uyanık, Ö. (2020). Angioedema developing in half of the tongue with captopril. Eurasian Journal of Critical Care, 2(3), 249-251.
AMA Akkan S, Uyanık Ö. Angioedema developing in half of the tongue with captopril. Eurasian j Crit Care. December 2020;2(3):249-251.
Chicago Akkan, Sedat, and Ömür Uyanık. “Angioedema Developing in Half of the Tongue With Captopril”. Eurasian Journal of Critical Care 2, no. 3 (December 2020): 249-51.
EndNote Akkan S, Uyanık Ö (December 1, 2020) Angioedema developing in half of the tongue with captopril. Eurasian Journal of Critical Care 2 3 249–251.
IEEE S. Akkan and Ö. Uyanık, “Angioedema developing in half of the tongue with captopril”., Eurasian j Crit Care, vol. 2, no. 3, pp. 249–251, 2020.
ISNAD Akkan, Sedat - Uyanık, Ömür. “Angioedema Developing in Half of the Tongue With Captopril”. Eurasian Journal of Critical Care 2/3 (December 2020), 249-251.
JAMA Akkan S, Uyanık Ö. Angioedema developing in half of the tongue with captopril. Eurasian j Crit Care. 2020;2:249–251.
MLA Akkan, Sedat and Ömür Uyanık. “Angioedema Developing in Half of the Tongue With Captopril”. Eurasian Journal of Critical Care, vol. 2, no. 3, 2020, pp. 249-51.
Vancouver Akkan S, Uyanık Ö. Angioedema developing in half of the tongue with captopril. Eurasian j Crit Care. 2020;2(3):249-51.

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