Abstract
References
- 1. Chepyala P, Olden K. Nausea and vomiting. Curr Treat Options Gastroenterol. 2008; 11: 135–144.
- 2. Singh P, Sonia SY, Braden Kuo. Nausea: a review of pathophysiology and therapeutics. Therapeutic advances in gastroenterology. 2016; 9(1): 98-112.
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- 5. Zamani M, Namdar B, Azizkhani R, Ahmadi O, Esmailian M. Comparing the antiemetic effects of ondansetron and metoclopramide in patients with minor head trauma. Emergency. 2015; 3(4): 137.
- 6. Al Jaadi S, Al Kindi Y, Al-Saadi T. Safety of metoclopramide in traumatic brain injury patients: A systematic review of literature. Romanian Neurosurgery. 2020; 512-517.
- 7. Hasler W, Chey W. Nausea and vomiting. Gastroenterology. 2003; 125: 1860–1867
- 8. Hornby P. Central neurocircuitry associated with emesis. Am J Med. 2001; 111:106S–112S.
- 9. Griddine A, Bush J. S. Ondansetron. StatPearls [Internet]. 2020.
- 10. Wilson EB, Bass CS, Abrameit W, Roberson R, Smith RW. Metoclopramide versus ondansetron in prophylaxis of nausea and vomiting for laparoscopic cholecystectomy. The American journal of surgery. 2001; 181(2): 138-141.
- 11. Abas MN, Tan PC, Azmi N, Omar SZ. Ondansetron compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial. Obstetrics & Gynecology. 2014; 123(6): 1272-1279.
Effect of Using Metoclopramide and Ondansetron in the Emergency Department on the Treatment Duration
Abstract
Objective: The complaint of nausea and vomiting can be a symptom or result of many diseases. It may impair the comfort and even the general condition of the patient. Therefore, patients admitted to the emergency room expect to correct these complaints as quickly as possible. The most commonly used drugs for this are metoclopramide and ondansetron. Materials and Methods: In our study; a one-month period, 99 patients who presented to our emergency department with complaints of nausea, vomiting, and diarrhea due to any disease were included (excluding trauma and cancer patients). It was noted how quickly the symptoms decreased when metoclopramide 10 mg or ondansetron 8 mg were administered intravenously. Results and Conclusion: After antiemetic application in the emergency room; We observed that the complaints disappeared more rapidly in patients treated with ondansetron than in patients treated with metoclopramide (mean 16/ minute, p<0,005).
Keywords
References
- 1. Chepyala P, Olden K. Nausea and vomiting. Curr Treat Options Gastroenterol. 2008; 11: 135–144.
- 2. Singh P, Sonia SY, Braden Kuo. Nausea: a review of pathophysiology and therapeutics. Therapeutic advances in gastroenterology. 2016; 9(1): 98-112.
- 3. Stern R. The psychophysiology of nausea. Acta Biol Hung. 2002; 53: 589–599
- 4. Moezzi M, Delirrooyfard A, Motamed H, Mortazavi MK. Antiemetic effects of metoclopramide with and without dexamethasone in children with minor head trauma: a single blind randomized clinical trial. Specialist EM. 2018; 188:7307–13.
- 5. Zamani M, Namdar B, Azizkhani R, Ahmadi O, Esmailian M. Comparing the antiemetic effects of ondansetron and metoclopramide in patients with minor head trauma. Emergency. 2015; 3(4): 137.
- 6. Al Jaadi S, Al Kindi Y, Al-Saadi T. Safety of metoclopramide in traumatic brain injury patients: A systematic review of literature. Romanian Neurosurgery. 2020; 512-517.
- 7. Hasler W, Chey W. Nausea and vomiting. Gastroenterology. 2003; 125: 1860–1867
- 8. Hornby P. Central neurocircuitry associated with emesis. Am J Med. 2001; 111:106S–112S.
- 9. Griddine A, Bush J. S. Ondansetron. StatPearls [Internet]. 2020.
- 10. Wilson EB, Bass CS, Abrameit W, Roberson R, Smith RW. Metoclopramide versus ondansetron in prophylaxis of nausea and vomiting for laparoscopic cholecystectomy. The American journal of surgery. 2001; 181(2): 138-141.
- 11. Abas MN, Tan PC, Azmi N, Omar SZ. Ondansetron compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial. Obstetrics & Gynecology. 2014; 123(6): 1272-1279.
Details
| Primary Language | English |
|---|---|
| Subjects | Emergency Medicine |
| Journal Section | Original Articles |
| Authors | |
| Publication Date | August 31, 2021 |
| Submission Date | February 25, 2021 |
| Acceptance Date | August 28, 2021 |
| Published in Issue | Year 2021 Volume: 3 Issue: 2 |
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