Case Report
Year 2021,
Volume: 3 Issue: 1, 22 - 24, 28.03.2021
Abstract
Granular cell tumor (GCT) is a rare soft tissue tumor derived from neural sheath and Schwann cells. They are usually located in skin, viscera, subcutaneous, submucosal tissues of the head and neck, especially in the tongue and mouth. Vulva is involved in 10% of the patients. The majority of GCTs tend to be benign however local recurrences may develop. Local surgical excision is curative for benign lesions. In this article, a benign vulvar granular cell tumor is presented.
Keywords
References
- Morrison JG, Gray Jr GF, Dao AH, Adkins Jr RB. Granular cell tumors. Am Surg 1987; 53:156-160.
- Abenoza P, Sibley RK. Granular cell myoma and schwannoma: fine structural and immunohistochemical study. Ultrastruct Pathol 1987; 11:19-28.
- Weber CO. Anatomische Untersuchang einer hypertropphischen Zunge nebst Bemrkungen uber die Nenbildung quergestreifter Muskelfasern. Virchows Arch A Pathol Anat Histopathol 1854; 7:115-125.
- Abrikossoff A. Uber Myome ansgehend von der guergestreiften willkuerlichen muskulature. Virchows Arch A Pathol Anat Histopathol 1926; 260:215-233.
- Horowitz IR, Copas P, Majmurdar B. Granular cell tumours of the vulva. Am J Obstet Gynecol 1995; 173:1710-1714.
- Lack EE, Worsham GF, Callihan MD, Crawford BE, Klappenbach P, Rowden G, et al. Granular cell tumor: A clinicopathologic study of 110 patients. J Surg Oncol 1987; 13:301-316.
- Armin A, Connely EM, Rowden G. An immunoperoxidase investigation of S- 100 protein in granular cell myoblastomas: evidence for Scwann cell derivation. Am J Clin Pathol 1983; 79:37-44.
- Jardines L, Cheung H, LiVolsi V, Hendrikson S, Brooks JJ. Malignant granular cell tumors: Report of a case and review of the literature. Surgery 1994; 116:49- 54.
- Cheewakriangkrai C, Sharma S, Deeb G, Lele S. A rare female genital tract tumor: Benign granular cell tumor of vulva: case report and review of the literature. Gynecol Oncol 2005; 97:656-658.
- Knowles KJ, Al-Delfi F, Abdulsattar J, et al. Malignant granular cell tumors: the role of electron microscopy in the definitive diagnosis of an extremely aggressive soft tissue neoplasm. Ultrastruct Pathol 2018; 42:304-311.
- Kardhashi A, Assunto Deliso M, Renna A, Trojano G, Zito FA, Trojano V. Benign granular cell tumor of the vulva: First report of multiple cases in a family. Gynecol Obstet Invest 2012; 73:341-348.
- Hong SC, Lim YK, Chew SH, Chia YN, Yam KL. Case report of granular cell tumor of the vulva and review of current literature. Gynecol Oncol Case Rep 2012; 3:20-22.
- Hale JL, Schwenk GR Jr, Wilson DB, Moriarty AT, Crabtree WN. Diagnosis of a vulvar granular cell tumor by fine needle aspiration biopsy. Acta Cytol 2002; 46:373-376.
- Billeret LV. Granular cell tumor. Epidemiology of 263 cases. Arch Anat Cytol Pathol 1999; 47:26-30.
- Fanburg-Smith JC, Meis-Kindblom JM, Fante R, Kindblom LG. Malignant granular cell tumor of soft tissue: diagnostic criteria and clinicopathologic correlation. Am J Surg Pathol 1998; 22:779-94.
- Apisarnthanaraz P. Granular cell tumor: an analysis of 16 cases and review of the literature. J Am Acad Dermatol 1981; 5:171-183.
- Gurzu S, Ciortea D, Tamasi A, et al. The immunohistochemical profile of granular cell (Abrikossoff) tumor suggests an endomesenchymal origin. Arch Dermatol Res 2015; 307:151-157.
- Cui Y, Tong SS, Zhang YH, Li HT. Granular cell tumor: a report of three cases and review of literature. Cancer Biomark 2018; 23: 173-178.
- Patabendige M, Wickramasooriya DJ, Dasanayake L. Granular cell tumor over the mons pubis: An uncommon tumor. Case Rep Obstet Gynecol 2019; 2019:1279137.
Year 2021,
Volume: 3 Issue: 1, 22 - 24, 28.03.2021
Abstract
Granular hücreli tümör, nöral kılıf ve Schwann hücrelerinden köken alan nadir bir yumuşak doku tümörüdür. Genellikle deri, iç organlar, baş ve boyunun subkutan ve submukozal dokuları, ağız ve dil yerleşimlidir. Hastaların %10 kadarında vulva tutulumu görülmektedir. Genelde benign karakterde olan bu tümörde lokal rekürrenslere rastlanmaktadır. Benign lezyonlar için lokal cerrahi eksizyon küratiftir. Bu makalede benign bir vulvar granular hücreli tümör olgusu sunulmuştur.
Keywords
References
- Morrison JG, Gray Jr GF, Dao AH, Adkins Jr RB. Granular cell tumors. Am Surg 1987; 53:156-160.
- Abenoza P, Sibley RK. Granular cell myoma and schwannoma: fine structural and immunohistochemical study. Ultrastruct Pathol 1987; 11:19-28.
- Weber CO. Anatomische Untersuchang einer hypertropphischen Zunge nebst Bemrkungen uber die Nenbildung quergestreifter Muskelfasern. Virchows Arch A Pathol Anat Histopathol 1854; 7:115-125.
- Abrikossoff A. Uber Myome ansgehend von der guergestreiften willkuerlichen muskulature. Virchows Arch A Pathol Anat Histopathol 1926; 260:215-233.
- Horowitz IR, Copas P, Majmurdar B. Granular cell tumours of the vulva. Am J Obstet Gynecol 1995; 173:1710-1714.
- Lack EE, Worsham GF, Callihan MD, Crawford BE, Klappenbach P, Rowden G, et al. Granular cell tumor: A clinicopathologic study of 110 patients. J Surg Oncol 1987; 13:301-316.
- Armin A, Connely EM, Rowden G. An immunoperoxidase investigation of S- 100 protein in granular cell myoblastomas: evidence for Scwann cell derivation. Am J Clin Pathol 1983; 79:37-44.
- Jardines L, Cheung H, LiVolsi V, Hendrikson S, Brooks JJ. Malignant granular cell tumors: Report of a case and review of the literature. Surgery 1994; 116:49- 54.
- Cheewakriangkrai C, Sharma S, Deeb G, Lele S. A rare female genital tract tumor: Benign granular cell tumor of vulva: case report and review of the literature. Gynecol Oncol 2005; 97:656-658.
- Knowles KJ, Al-Delfi F, Abdulsattar J, et al. Malignant granular cell tumors: the role of electron microscopy in the definitive diagnosis of an extremely aggressive soft tissue neoplasm. Ultrastruct Pathol 2018; 42:304-311.
- Kardhashi A, Assunto Deliso M, Renna A, Trojano G, Zito FA, Trojano V. Benign granular cell tumor of the vulva: First report of multiple cases in a family. Gynecol Obstet Invest 2012; 73:341-348.
- Hong SC, Lim YK, Chew SH, Chia YN, Yam KL. Case report of granular cell tumor of the vulva and review of current literature. Gynecol Oncol Case Rep 2012; 3:20-22.
- Hale JL, Schwenk GR Jr, Wilson DB, Moriarty AT, Crabtree WN. Diagnosis of a vulvar granular cell tumor by fine needle aspiration biopsy. Acta Cytol 2002; 46:373-376.
- Billeret LV. Granular cell tumor. Epidemiology of 263 cases. Arch Anat Cytol Pathol 1999; 47:26-30.
- Fanburg-Smith JC, Meis-Kindblom JM, Fante R, Kindblom LG. Malignant granular cell tumor of soft tissue: diagnostic criteria and clinicopathologic correlation. Am J Surg Pathol 1998; 22:779-94.
- Apisarnthanaraz P. Granular cell tumor: an analysis of 16 cases and review of the literature. J Am Acad Dermatol 1981; 5:171-183.
- Gurzu S, Ciortea D, Tamasi A, et al. The immunohistochemical profile of granular cell (Abrikossoff) tumor suggests an endomesenchymal origin. Arch Dermatol Res 2015; 307:151-157.
- Cui Y, Tong SS, Zhang YH, Li HT. Granular cell tumor: a report of three cases and review of literature. Cancer Biomark 2018; 23: 173-178.
- Patabendige M, Wickramasooriya DJ, Dasanayake L. Granular cell tumor over the mons pubis: An uncommon tumor. Case Rep Obstet Gynecol 2019; 2019:1279137.
There are 19 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Obstetrics and Gynaecology |
| Journal Section | Case Report |
| Authors | |
| Publication Date | March 28, 2021 |
| Acceptance Date | January 1, 2021 |
| Published in Issue | Year 2021 Volume: 3 Issue: 1 |
