Abstract
Amaç: Bu çalışma hastanemizde doğum yapmış gebelerin postpartum dönemde venöz tromboemboli (VTE) risk faktörlerinin değerlendirilmesi için planlanmıştır.
Materyal ve method: Çalışma retrospektif olarak postpartum dönemdeki 92 hastanın VTE risk faktörleri; önceden varolan risk faktörleri ve gebeliğe özgü risk faktörleri adı altında değerlendirildi. Hasta dağılımı bu risk faktörlerine göre sayısı ve yüzde oranı ile hesaplandı. VTE risk faktör skorlaması ACOG’a göre düzenlenmiş ‘Venöz tromboemboli risk değerlendirme formu’ na uygun olarak değerlendirilmiştir.
Bulgular: Önceden varolan risk faktörleri içinde varolan VTE öyküsü, düşük riskli trombofili ve yüksek riskli trombofili varlığı ile ilgili hastamız yoktu. Obezitede BMI ≥ 30 olan 48 hasta ( % 41,3) mevcuttu. Gebeliğe özgü risk faktörleri içinde uzamış doğum eylemi ve ölü doğum yapan hastamız yoktu. Bu grup içinde en fazla hasta sayısı paritesi ≥ 3 olan 31 (%33,6) hastamız mevcuttu. VTE skoru 3 puan olan 36 (%39,1) hasta saptandı. VTE skoru 0 ve 1 puan olan grup lar, sırasıyla 9 (%9,7) ve 9 (%9,7), en az hasta sayısına sahipti.
Sonuç: Çalışmada postpartum dönemde VTE bağlı komplikasyon gelişmemiştir. Bu durum doğum sonrası hastalarda VTE risk faktörlerinin değerlendirilmesinin ve yönetiminin önemini bir kez daha vurgulamaktadır. VTE bağlı komplikasyonları değerlendirmek için daha çok sayıda hasta grubu olan ileri çalışmalara ihtiyaç vardır.
Project Number
11/05
References
- Petersen EE, Davis NL, Goodman D, et al. Vital Signs: Pregnancy- Related Deaths, United States, 2011-2015, and Strategies for Prevention, 13 States, 2013-2017. MMWR Morb Mortal Wkly Rep. 2019;68:423-429.
- Parunov LA, Soshitova NP, Ovanesov MV, Panteleev MA, Serebriyskiy II. Epidemiology of venous thromboembolism (VTE) associated with pregnancy. Birth Defects Res C Embryo Today 2015;105:167-184.
- Abe K, Kuklina EV, Hooper WC, Callaghan WM. Venous thromboembolism as a cause of severe maternal morbidity and mortality in the United States. Semin Perinatol 2019;43:200-4.
- Wik HS, Jacobsen AF, Sandvik L, Sandset PM. Prevalence and predictors for post-thrombotic syndrome 3 to 16 years after pregnancy-related venous thrombosis: a population-based, cross-sectional, case-control study. J Thromb Haemost 2012;10: 840-847.
- Testa S, Passamonti SM, Paoletti O, et al. Pregnancy Health-care Program” for the prevention of venous thromboembolism in pregnancy. Intern Emerg Med 2015;10: 129-134.
- American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Obstetrics. ACOG Practice Bulletin No. 196: Thromboembolism in Pregnancy. Obstet Gynecol. 2018;132(1):1-17.
- Elgendy IY, Fogerty A, Blanco-Molina ´A, et al. Clinical Characteristics and Outcomes of Women Presenting with Venous Thromboembolism during Pregnancy and Postpartum Period: Findings from the RIETE Registry. Thromb Haemost 2020;120: 1454-1462.
- Elkaryoni A, Secemsky EA, Mamas MA, Monreal M, Weinberg I, Pepine CJ. Acute pulmonary embolism during pregnancy and puerperium: National trends and in-hospital outcomes. Mayo Clin Proc 2021;96:2102-2113.
- James AH, Jamison MG, Brancazio LR, Myers ER. Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality. Am J Obstet Gynecol 2006;194:1311-1315.
- Larsen TB, Sørensen HT, Gislum M, Johnsen SP. Maternal smoking, obesity, and risk of venous thromboembolism during pregnancy and the puerperium: a population-based nested case-control study. Thromb Res 2007; 120:505-509.
- Pabinger I, Grafenhofer H, Kyrle PA, et al. Temporary increase in the risk for recurrence during pregnancy in women with a history of venous thromboembolism. Blood 2002;100:1060-1062.
- Liu S, Rouleau J, Joseph KS, et al. Epidemiology of pregnancy-associated venous thromboembolism: a population-based study in Canada. J Obstet Gynaecol Can 2009; 31:611-620.
- Lindqvist P, Dahlb¨ack B, Marˆs´al K. Thrombotic risk during pregnancy: a population study. Obstet Gynecol 1999; 94:595-599.
- Jacobsen AF, Skjeldestad FE, Sandset PM. Incidence and risk patterns of venous thromboembolism in pregnancy and puerperium-a register-based case-control study. Am J Obstet Gynecol 2008;198:233. e1-7.
- Kane EV, Calderwood C, Dobbie R, Morris C, Roman E, Greer IA. A population-based study of venous thrombosis in pregnancy in Scotland 1980-2005. Eur J Obstet Gynecol Reprod Biol 2013;169:223-229.
Abstract
Purpose: This study was planned to evaluate the risk factors of venous thromboembolism (VTE) in the postpartum period of pregnant womwn who delivered in our hospital.
Material and method: This study retropectively examined the VTE risk factors of 92 patients in the postpartum period; they were evaluated under the names of pre-existing risk factors and pregnancy –specific risk factors. Patient distribution was calculated by number and percentage rate according to these risk factors. VTE risk factor scoring was evaluated in accordance with the ‘Venous thromboembolism risk assessment form’ prepared according to ACOG.
Results: We did not have any patient with pre-existing risk factors such as a history of VTE, presence of low – risk thrombophilia or presence of high-risk thrombophilia.There were 48 patients ( 41.3%) with BMI ≥ 30. We did not have any patients with prolonged labor or stillbirth, which are pegnancy- specific risk factors. In this group, we had 31 (33.6% ) patients with the highest number of patients with parity >3.. VTE score of 3 points was detected in 36 (39.1%) patients. The group with VTE scores of 0 and 1 point had the least number of patients; 9 (9.7%) and 9 (9.7%), respectively.
Conclusion: In the study, no VTE-related complications developed in the postpartum period. This situation once again emphasizes the importance of evaluation and management of VTE risk factors in postpartum patients. Further studies with larger patient groups are needed to evaluate VTE –related complications.
Project Number
11/05
References
- Petersen EE, Davis NL, Goodman D, et al. Vital Signs: Pregnancy- Related Deaths, United States, 2011-2015, and Strategies for Prevention, 13 States, 2013-2017. MMWR Morb Mortal Wkly Rep. 2019;68:423-429.
- Parunov LA, Soshitova NP, Ovanesov MV, Panteleev MA, Serebriyskiy II. Epidemiology of venous thromboembolism (VTE) associated with pregnancy. Birth Defects Res C Embryo Today 2015;105:167-184.
- Abe K, Kuklina EV, Hooper WC, Callaghan WM. Venous thromboembolism as a cause of severe maternal morbidity and mortality in the United States. Semin Perinatol 2019;43:200-4.
- Wik HS, Jacobsen AF, Sandvik L, Sandset PM. Prevalence and predictors for post-thrombotic syndrome 3 to 16 years after pregnancy-related venous thrombosis: a population-based, cross-sectional, case-control study. J Thromb Haemost 2012;10: 840-847.
- Testa S, Passamonti SM, Paoletti O, et al. Pregnancy Health-care Program” for the prevention of venous thromboembolism in pregnancy. Intern Emerg Med 2015;10: 129-134.
- American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Obstetrics. ACOG Practice Bulletin No. 196: Thromboembolism in Pregnancy. Obstet Gynecol. 2018;132(1):1-17.
- Elgendy IY, Fogerty A, Blanco-Molina ´A, et al. Clinical Characteristics and Outcomes of Women Presenting with Venous Thromboembolism during Pregnancy and Postpartum Period: Findings from the RIETE Registry. Thromb Haemost 2020;120: 1454-1462.
- Elkaryoni A, Secemsky EA, Mamas MA, Monreal M, Weinberg I, Pepine CJ. Acute pulmonary embolism during pregnancy and puerperium: National trends and in-hospital outcomes. Mayo Clin Proc 2021;96:2102-2113.
- James AH, Jamison MG, Brancazio LR, Myers ER. Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality. Am J Obstet Gynecol 2006;194:1311-1315.
- Larsen TB, Sørensen HT, Gislum M, Johnsen SP. Maternal smoking, obesity, and risk of venous thromboembolism during pregnancy and the puerperium: a population-based nested case-control study. Thromb Res 2007; 120:505-509.
- Pabinger I, Grafenhofer H, Kyrle PA, et al. Temporary increase in the risk for recurrence during pregnancy in women with a history of venous thromboembolism. Blood 2002;100:1060-1062.
- Liu S, Rouleau J, Joseph KS, et al. Epidemiology of pregnancy-associated venous thromboembolism: a population-based study in Canada. J Obstet Gynaecol Can 2009; 31:611-620.
- Lindqvist P, Dahlb¨ack B, Marˆs´al K. Thrombotic risk during pregnancy: a population study. Obstet Gynecol 1999; 94:595-599.
- Jacobsen AF, Skjeldestad FE, Sandset PM. Incidence and risk patterns of venous thromboembolism in pregnancy and puerperium-a register-based case-control study. Am J Obstet Gynecol 2008;198:233. e1-7.
- Kane EV, Calderwood C, Dobbie R, Morris C, Roman E, Greer IA. A population-based study of venous thrombosis in pregnancy in Scotland 1980-2005. Eur J Obstet Gynecol Reprod Biol 2013;169:223-229.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Obstetrics and Gynaecology |
| Journal Section | Research Article |
| Authors | |
| Project Number | 11/05 |
| Publication Date | December 28, 2023 |
| Submission Date | December 8, 2023 |
| Acceptance Date | December 24, 2023 |
| Published in Issue | Year 2023 Volume: 5 Issue: 4 |
