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The Effect of Ocular and Systemic Factors on Ocular Pulse Amplitude

Year 2012, Volume: 17 Issue: 4, 215 - 218, 01.08.2012

İrfan Uzun

Abstract

Objective: To assess the effect of ocular and systemic factors on ocular pulse amplitude in patients with primary open angle glaucoma. Materials and Methods: Fifty eyes of 50 primary open angle glaucoma patients were included in this study. Patients underwent routine ophthalmologic examination with intraocular pressure and ocular pulse amplitude measurement by Pascal dynamic contour tonometry and perimetry by Octopus automatic perimeter. The factors related to ocular pulse amplitude were statistically evaluated. Results: The mean age of the patients was 63±9,76 years. Of 50 patients, 29(58%) were female and 21(42%) were male. The mean ocular pulse amplitude, intraocular pressure, age, duration of glaucoma, MD(mean deviasyon) and sLV(loss variance) of perimetry measurement were as follows; 2,87±0,86 mmHg, 17,01±2,59 mmHg, 63±9,76 year, 32,7±46,92 month, 6,06±3,7, 4,23±1,55. There was no correlation between ocular pulse amplitude and age, gender, systemic disease, visual acuity, duration of glaucoma, glaucoma drugs, MD and sLV(p>0.05). Ocular pulse amplitude showed statistically significant positive correlation with intraocular pressure (p=0,003). Conclusion: Ocular pulse amplitude was demonstrated to have significant association with intraocular pressure.

Keywords

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References

  • 1. Stewart JA, Kampman O, Huuhka M, et al. ACE polymorphism and response to electroconvulsive therapy in major depression. Neurosci Lett 2009; 458: 122-5.
  • 2. Grieshaber MC, Katamay R, Gugleta K, Kochkorov A, Flammer J, Orgul S. Relationship between ocular pulse amplitude and systemic blood pressure measurements. Acta Ophthalmol 2009; 87: 329-34.
  • 3. Villas-Boas FS, Doi LM, Sousa AK, Melo LA Jr. Correlation between diurnal variation of intraocular pressure, ocular pulse amplitude and corneal structural properties. Arq Bras Oftalmol 2009; 72: 296-301.
  • 4. Kanngiesser HE, Kniestedt C, Robert YC. Dynamic contour tonometry: presentation of a new tonometer. J Glaucoma 2005; 14: 344-50.
  • 5. Kynigopoulos M, Tzamalis A, Ntampos K, Schlote T. Decreased ocular pulse amplitude associated with functional and structural damage in open-angle glaucoma. Eur J Ophthalmol 2012; 22: 111-6.
  • 6. Vulsteke C, Stalmans I, Fieuws S, Zeyen T. Correlation between ocular pulse amplitude measured by dynamic contour tonometer and visual field defects. Graefes Arch Clin Exp Ophthalmol 2008; 246: 559-65
  • 7. Alimgil ML, Benian O, Esgin H, Erda S. Ocular pulse amplitude in patients with Graves' disease: a preliminary study. Acta Ophthalmol Scand 1999; 77: 694-6.
  • 8. Schmidt KG, Pillunat LE, Kohler K, Flammer J. Ocular pulse amplitude is reduced in patients with advanced retinitis pigmentosa. Br J Ophthalmol 2001; 85: 678-82.
  • 9. Kaufmann C, Bachmann LM, Robert YC, Thiel MA. Ocular pulse amplitude in healthy subjects as measured by dynamic contour tonometry. Arch Ophthalmol 2006; 124: 1104-8.
  • 10. Ito K, Tawara A, Kubota T, Harada Y. IOP measured by dynamic contour tonometry correlates with IOP measured by Goldmann applanation tonometry and non-contact tonometry in Japanese individuals. J Glaucoma 2012; 21: 35-40.
  • 11. Francis BA, Hsieh A, Lai MY et al. Effects of corneal thickness, corneal curvature, and intraocular pressure level on Goldmann applanation tonometry and dynamic contour tonometry. Ophthalmology 2007; 114: 20-6.
  • 12. Saenz-Frances F, Garcia-Catalan R, Jerez-Fidalgo M et al. [Comparison of Goldmann applanation and dynamic contour tonometry measurements: effects of corneal morphometry]. Arch Soc Esp Oftalmol 2011; 86: 287-91.
  • 13. Tabuchi H, Kiuchi Y, Ohsugi H, Nakakura S, Han Z. Effects of corneal thickness and axial length on intraocular pressure and ocular pulse amplitude before and after cataract surgery. Can J Ophthalmol 2011; 46: 242-6.
  • 14. Von Schulthess SR, Kaufmann C, Bachmann LM, Yanar A, Thiel MA. Ocular pulse amplitude after trabeculectomy. Graefes Arch Clin Exp Ophthalmol 2006; 244: 46-51.
  • 15. Ocakoğlu Ö, Uçar D. Pascal dinamik kontür tonometresi kullanarak glokomlu ve oküler hipertansif hastalarda oküler nabız genliği ölçümleri. Turk J Ophthalmol 2008; 38: 198- 203.
  • 16. Dastiridou AI, Ginis HS, De Brouwere D, Tsilimbaris MK, Pallikaris IG. Ocular rigidity, ocular pulse amplitude, and pulsatile ocular blood flow: the effect of intraocular pressure. Invest Ophthalmol Vis Sci 2009; 50: 5718-22.
  • 17. Punjabi OS, Ho HK, Kniestedt C, Bostrom AG, Stamper RL, Lin SC. Intraocular pressure and ocular pulse amplitude comparisons in different types of glaucoma using dynamic contour tonometry. Curr Eye Res 2006; 31: 851-62.
  • 18. Breusegem C, Fieuws S, Zeyen T, Stalmans I. The effect of trabeculectomy on ocular pulse amplitude. Invest Ophthalmol Vis Sci 2010; 51: 231-5.
  • 19. Plange N, Rennings C, Herr A et al. Ocular pulse amplitude before and after cataract surgery. Curr Eye Res 2012; 37: 115- 9.
  • 20. Knecht PB, Bosch MM, Michels S et al. The ocular pulse amplitude at different intraocular pressure: a prospective study. Acta Ophthalmol 2011; 89: 466-71.
  • 21. Jordao ML, Lupinacci AP, Ferreira EL, Enomoto IJ, Costa VP. Influence of age, central corneal thickness, and quality score on dynamic contour tonometry. Eye (Lond) 2009; 23: 1364-9.
  • 22. Pourjavan S, Boelle PY, Detry-Morel M, De Potter P. Physiological diurnal variability and characteristics of the ocular pulse amplitude (OPA) with the dynamic contour tonometer (DCT-Pascal). Int Ophthalmol 2007; 27: 357-60.
  • 23. Kotecha A, White ET, Shewry JM, Garway-Heath DF. The relative effects of corneal thickness and age on Goldmann applanation tonometry and dynamic contour tonometry. Br J Ophthalmol 2005; 89: 1572-5.
  • 24. Karadağ R, Kanbay M. Tedavi ile kontrol altında olan sistemik hipertansiyonun göz içi basıncı ve oküler puls amplitüde etkisi. Glo-Kat 2008; 3: 255-7.
  • 25. Schmidt KG, Dick B, von Rückmann A, Pillunat LE. Ocular pulse amplitude and local carbonic anhydrase inhibition. Ophthalmologe 1997; 94: 659-64.
  • 26. Bayerle-Eder M, Kolodjaschna J, Wolzt M , Polska E, Gasic S, Schmetterer L. Effect of a nifedipine induced reduction in blood pressure on the association between ocular pulse amplitude and ocular fundus pulsation amplitude in systemic hypertension. Br J Ophthalmol 2005; 89: 704-8.
  • 27. Yorgun MA, Yülek F, Toklu Y, Altıntaş AGK, Şimşek Ş. İntravitreal bevacizumab enjeksiyonu sonrası göz içi basıncı ve oküler pulse amplitudü değişiminin incelenmesi. Glo-Kat 2008; 3: 258-60.

Oküler ve Sistemik Faktörlerin Oküler Nabız Genliği Üzerine Olan Etkisi

Year 2012, Volume: 17 Issue: 4, 215 - 218, 01.08.2012

İrfan Uzun

Abstract

Amaç: Primer açık açılı glokomu olan hastalarda oküler ve sistemik faktörlerin oküler nabız genliği üzerine olan etkisini araştırmak. Gereç ve Yöntem: Primer açık açılı glokomu olan 50 hastanın 50 gözü çalışmaya alındı. Hastaların rutin oftalmolojik muayeneleri, Pascal tonometresi ile göz içi basıncı ve oküler nabız genliği ölçümü, Octopus otomatik perimetresi ile görme alanı ölçümü yapıldı. Oküler nabız genliği ile ilişkili faktörler istatistiksel olarak değerlendirildi. Bulgular: Hastaların yaş ortalaması 63±9,76 yıl idi. Hastaların 29'u (%58) kadın, 21'i (%42) erkek idi. Hastaların oküler nabız genliği, göz içi basıncı, yaş, glokomun süresi ve görme alanı ölçümleriyle elde edilen MD(mean deviasyon) ve sLV(loss variance) ortalama değerleri sırasıyla 2,87±0,86 mmHg, 17,01±2,59 mmHg, 63±9,76 yıl, 32,7±46,92 ay, 6,06±3,7, 4,23±1,55 olarak saptandı. Yaş, cinsiyet, sistemik hastalıklar, görme keskinliği, glokumun süresi, glokom ilaçları, MD ve sLV değerlerinin oküler nabız genliğini etkilemedikleri bulundu (p>0.05). Göz içi basıncı ile oküler nabız genliği arasında ise istatistiksel olarak anlamlı derecede pozitif korelasyon olduğu bulundu( p=0,003). Sonuç: Oküler nabız genliği ile göz içi basıncı arasında anlamlı bir ilişki olduğu gösterildi.

Keywords

Primer açık açılı glokom Oküler nabız genliği Göz içi basıncı

References

  • 1. Stewart JA, Kampman O, Huuhka M, et al. ACE polymorphism and response to electroconvulsive therapy in major depression. Neurosci Lett 2009; 458: 122-5.
  • 2. Grieshaber MC, Katamay R, Gugleta K, Kochkorov A, Flammer J, Orgul S. Relationship between ocular pulse amplitude and systemic blood pressure measurements. Acta Ophthalmol 2009; 87: 329-34.
  • 3. Villas-Boas FS, Doi LM, Sousa AK, Melo LA Jr. Correlation between diurnal variation of intraocular pressure, ocular pulse amplitude and corneal structural properties. Arq Bras Oftalmol 2009; 72: 296-301.
  • 4. Kanngiesser HE, Kniestedt C, Robert YC. Dynamic contour tonometry: presentation of a new tonometer. J Glaucoma 2005; 14: 344-50.
  • 5. Kynigopoulos M, Tzamalis A, Ntampos K, Schlote T. Decreased ocular pulse amplitude associated with functional and structural damage in open-angle glaucoma. Eur J Ophthalmol 2012; 22: 111-6.
  • 6. Vulsteke C, Stalmans I, Fieuws S, Zeyen T. Correlation between ocular pulse amplitude measured by dynamic contour tonometer and visual field defects. Graefes Arch Clin Exp Ophthalmol 2008; 246: 559-65
  • 7. Alimgil ML, Benian O, Esgin H, Erda S. Ocular pulse amplitude in patients with Graves' disease: a preliminary study. Acta Ophthalmol Scand 1999; 77: 694-6.
  • 8. Schmidt KG, Pillunat LE, Kohler K, Flammer J. Ocular pulse amplitude is reduced in patients with advanced retinitis pigmentosa. Br J Ophthalmol 2001; 85: 678-82.
  • 9. Kaufmann C, Bachmann LM, Robert YC, Thiel MA. Ocular pulse amplitude in healthy subjects as measured by dynamic contour tonometry. Arch Ophthalmol 2006; 124: 1104-8.
  • 10. Ito K, Tawara A, Kubota T, Harada Y. IOP measured by dynamic contour tonometry correlates with IOP measured by Goldmann applanation tonometry and non-contact tonometry in Japanese individuals. J Glaucoma 2012; 21: 35-40.
  • 11. Francis BA, Hsieh A, Lai MY et al. Effects of corneal thickness, corneal curvature, and intraocular pressure level on Goldmann applanation tonometry and dynamic contour tonometry. Ophthalmology 2007; 114: 20-6.
  • 12. Saenz-Frances F, Garcia-Catalan R, Jerez-Fidalgo M et al. [Comparison of Goldmann applanation and dynamic contour tonometry measurements: effects of corneal morphometry]. Arch Soc Esp Oftalmol 2011; 86: 287-91.
  • 13. Tabuchi H, Kiuchi Y, Ohsugi H, Nakakura S, Han Z. Effects of corneal thickness and axial length on intraocular pressure and ocular pulse amplitude before and after cataract surgery. Can J Ophthalmol 2011; 46: 242-6.
  • 14. Von Schulthess SR, Kaufmann C, Bachmann LM, Yanar A, Thiel MA. Ocular pulse amplitude after trabeculectomy. Graefes Arch Clin Exp Ophthalmol 2006; 244: 46-51.
  • 15. Ocakoğlu Ö, Uçar D. Pascal dinamik kontür tonometresi kullanarak glokomlu ve oküler hipertansif hastalarda oküler nabız genliği ölçümleri. Turk J Ophthalmol 2008; 38: 198- 203.
  • 16. Dastiridou AI, Ginis HS, De Brouwere D, Tsilimbaris MK, Pallikaris IG. Ocular rigidity, ocular pulse amplitude, and pulsatile ocular blood flow: the effect of intraocular pressure. Invest Ophthalmol Vis Sci 2009; 50: 5718-22.
  • 17. Punjabi OS, Ho HK, Kniestedt C, Bostrom AG, Stamper RL, Lin SC. Intraocular pressure and ocular pulse amplitude comparisons in different types of glaucoma using dynamic contour tonometry. Curr Eye Res 2006; 31: 851-62.
  • 18. Breusegem C, Fieuws S, Zeyen T, Stalmans I. The effect of trabeculectomy on ocular pulse amplitude. Invest Ophthalmol Vis Sci 2010; 51: 231-5.
  • 19. Plange N, Rennings C, Herr A et al. Ocular pulse amplitude before and after cataract surgery. Curr Eye Res 2012; 37: 115- 9.
  • 20. Knecht PB, Bosch MM, Michels S et al. The ocular pulse amplitude at different intraocular pressure: a prospective study. Acta Ophthalmol 2011; 89: 466-71.
  • 21. Jordao ML, Lupinacci AP, Ferreira EL, Enomoto IJ, Costa VP. Influence of age, central corneal thickness, and quality score on dynamic contour tonometry. Eye (Lond) 2009; 23: 1364-9.
  • 22. Pourjavan S, Boelle PY, Detry-Morel M, De Potter P. Physiological diurnal variability and characteristics of the ocular pulse amplitude (OPA) with the dynamic contour tonometer (DCT-Pascal). Int Ophthalmol 2007; 27: 357-60.
  • 23. Kotecha A, White ET, Shewry JM, Garway-Heath DF. The relative effects of corneal thickness and age on Goldmann applanation tonometry and dynamic contour tonometry. Br J Ophthalmol 2005; 89: 1572-5.
  • 24. Karadağ R, Kanbay M. Tedavi ile kontrol altında olan sistemik hipertansiyonun göz içi basıncı ve oküler puls amplitüde etkisi. Glo-Kat 2008; 3: 255-7.
  • 25. Schmidt KG, Dick B, von Rückmann A, Pillunat LE. Ocular pulse amplitude and local carbonic anhydrase inhibition. Ophthalmologe 1997; 94: 659-64.
  • 26. Bayerle-Eder M, Kolodjaschna J, Wolzt M , Polska E, Gasic S, Schmetterer L. Effect of a nifedipine induced reduction in blood pressure on the association between ocular pulse amplitude and ocular fundus pulsation amplitude in systemic hypertension. Br J Ophthalmol 2005; 89: 704-8.
  • 27. Yorgun MA, Yülek F, Toklu Y, Altıntaş AGK, Şimşek Ş. İntravitreal bevacizumab enjeksiyonu sonrası göz içi basıncı ve oküler pulse amplitudü değişiminin incelenmesi. Glo-Kat 2008; 3: 258-60.
There are 27 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

İrfan Uzun

Publication Date August 1, 2012
Published in Issue Year 2012 Volume: 17 Issue: 4

Cite

APA Uzun, İ. (2012). Oküler ve Sistemik Faktörlerin Oküler Nabız Genliği Üzerine Olan Etkisi. Fırat Tıp Dergisi, 17(4), 215-218.
AMA Uzun İ. Oküler ve Sistemik Faktörlerin Oküler Nabız Genliği Üzerine Olan Etkisi. Fırat Tıp Dergisi. August 2012;17(4):215-218.
Chicago Uzun, İrfan. “Oküler Ve Sistemik Faktörlerin Oküler Nabız Genliği Üzerine Olan Etkisi”. Fırat Tıp Dergisi 17, no. 4 (August 2012): 215-18.
EndNote Uzun İ (August 1, 2012) Oküler ve Sistemik Faktörlerin Oküler Nabız Genliği Üzerine Olan Etkisi. Fırat Tıp Dergisi 17 4 215–218.
IEEE İ. Uzun, “Oküler ve Sistemik Faktörlerin Oküler Nabız Genliği Üzerine Olan Etkisi”, Fırat Tıp Dergisi, vol. 17, no. 4, pp. 215–218, 2012.
ISNAD Uzun, İrfan. “Oküler Ve Sistemik Faktörlerin Oküler Nabız Genliği Üzerine Olan Etkisi”. Fırat Tıp Dergisi 17/4 (August 2012), 215-218.
JAMA Uzun İ. Oküler ve Sistemik Faktörlerin Oküler Nabız Genliği Üzerine Olan Etkisi. Fırat Tıp Dergisi. 2012;17:215–218.
MLA Uzun, İrfan. “Oküler Ve Sistemik Faktörlerin Oküler Nabız Genliği Üzerine Olan Etkisi”. Fırat Tıp Dergisi, vol. 17, no. 4, 2012, pp. 215-8.
Vancouver Uzun İ. Oküler ve Sistemik Faktörlerin Oküler Nabız Genliği Üzerine Olan Etkisi. Fırat Tıp Dergisi. 2012;17(4):215-8.