Year 2016,
Volume: 6 Issue: 1, 67 - 69, 19.10.2016
Abstract
Etilenglikol, dihidrik alkoller grubundan, renksiz, kokusuz, tatlı ve suda çözünen bir maddedir. Etilenglikol içeren maddelerin kaza ya da intihar amaçlı alınması sonucu ağır
metabolik asidoz, santral sinir sistemi depresyonu ve oligürik akut böbrek yetmezliği meydana gelir. Erken tanı ve tedavi ile mortalite anlamlı bir düzeyde azalabilmektedir. Biz kaza ile antifriz içtikten sonra etilenglikol zehirlenmesine bağlı olarak ağır metabolik asidoz, koma ve akut böbrek yetmezliği tablosu gelişmiş bir vakayı sunduk.
References
- Jacobsen D and McMartin KE, Antidotes for methanol and ethylene glycol poisoning. J Toxicol Clin Toxicol, 1997. 35(2): p. 127-43.
- Jacobsen D and McMartin KE, Methanol and ethylene glycol poisonings. Mechanism of toxicity, clinical cour- se, diagnosis and treatment. Med Toxicol, 1986. 1(5): p. 309-34.
- Roscher AA, A new histochemical method for the de- monstration of calcium oxalate in tissues following ethylene glycol poisoning. Am J Clin Pathol, 1971. 55(1): p. 99-104.
- Brent J, Current management of ethylene glycol poiso- ning. Drugs, 2001. 61(7): p. 979-88.
- Caravati EM, Erdman AR, Christianson G, et al., Eth- ylene glycol exposure: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol (Phila), 2005. 43(5): p. 327-45.
- Barceloux DG, Krenzelok EP, Olson K, et al., American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc Committee. J Toxicol Clin Toxicol, 1999. 37(5): p. 537- 60.
- Brent J, McMartin K, Phillips S, et al., Fomepizole for the treatment of ethylene glycol poisoning. Methyl- pyrazole for Toxic Alcohols Study Group. N Engl J Med, 1999. 340(11): p. 832-8.
Year 2016,
Volume: 6 Issue: 1, 67 - 69, 19.10.2016
Abstract
Ethylene glycol is a colorless, odorless, sweet, water-soluble substance from the group of dihydric alcohols. As a result of taking ethylene-containing material for suicide purpose or as an accident, serious metabolic acidosis, central nervous system depression and oliguric acute renal failure occur. Early diagnosis and treatment can reduce mortality at a significant level. We present a case with severe metabolic acidosis, coma and acute renal failure due to ethylene glycol intoxication after drinking antifreeze accidentally.
References
- Jacobsen D and McMartin KE, Antidotes for methanol and ethylene glycol poisoning. J Toxicol Clin Toxicol, 1997. 35(2): p. 127-43.
- Jacobsen D and McMartin KE, Methanol and ethylene glycol poisonings. Mechanism of toxicity, clinical cour- se, diagnosis and treatment. Med Toxicol, 1986. 1(5): p. 309-34.
- Roscher AA, A new histochemical method for the de- monstration of calcium oxalate in tissues following ethylene glycol poisoning. Am J Clin Pathol, 1971. 55(1): p. 99-104.
- Brent J, Current management of ethylene glycol poiso- ning. Drugs, 2001. 61(7): p. 979-88.
- Caravati EM, Erdman AR, Christianson G, et al., Eth- ylene glycol exposure: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol (Phila), 2005. 43(5): p. 327-45.
- Barceloux DG, Krenzelok EP, Olson K, et al., American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc Committee. J Toxicol Clin Toxicol, 1999. 37(5): p. 537- 60.
- Brent J, McMartin K, Phillips S, et al., Fomepizole for the treatment of ethylene glycol poisoning. Methyl- pyrazole for Toxic Alcohols Study Group. N Engl J Med, 1999. 340(11): p. 832-8.
There are 7 citations in total.
Details
| Subjects | Health Care Administration |
|---|---|
| Journal Section | Letter to the Editor |
| Authors | |
| Publication Date | October 19, 2016 |
| Published in Issue | Year 2016 Volume: 6 Issue: 1 |