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Prospects for the search for new biologically active compounds among the derivatives of the heterocyclic system of 1,2,4-triazole

Year 2022, Volume: 42 Issue: 3, 175 - 186, 01.09.2022

Yurii Sameliuk Andrii Kaplaushenko Natalia Nedorezanıuk Liusine Ostretsova Feodosiia Diakova Bogdan Gutyj

https://doi.org/10.52794/hujpharm.1019625
Cited By: 5

Abstract

The purpose of this literature review was to systematize data from studies of the biological activity of 1,2,4-triazole derivatives with substituents in positions 4 and 5. The authors set the task of forming an idea of current directions in the selection of substitutions for 1,2,4-triazole based on research.
As a result of the study, 75 literature sources were analyzed. This made it possible to form a further vector in terms of searching for biologically active structures among 1,2,4-triazole derivatives. The review develops a modern approach to the search for biologically active substances among 1,2,4-triazole derivatives. Sys- tematized data on the nature of substituents in the core of 1,2,4-triazole, which affect a specific type of activity.
The search material was selected over the past decade with the highest number of citations at the time of literature analysis.

Keywords

Biological activity bibliosemantic method organic synthesis 1 2 4-triazole

Supporting Institution

Zaporizhzhia State Medical University, Faculty of Pharmacy, Department of physical and colloidal chemistry, Zaporizhzhia, Ukraine

Project Number

2

Thanks

thanks to Hacettepe University Journal of Faculty of Pharmacy

References

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Prospects for the search for new biologically active compounds among the derivatives of the heterocyclic system of 1,2,4-triazole

Year 2022, Volume: 42 Issue: 3, 175 - 186, 01.09.2022

Yurii Sameliuk Andrii Kaplaushenko Natalia Nedorezanıuk Liusine Ostretsova Feodosiia Diakova Bogdan Gutyj

https://doi.org/10.52794/hujpharm.1019625
Cited By: 5

Abstract

The purpose of this literature review was to systematize data from studies of the biological activity of 1,2,4-triazole derivatives with substituents in positions 4 and 5. The authors set the task of forming an idea of current directions in the selection of substitutions for 1,2,4-triazole based on research.
As a result of the study, 75 literature sources were analyzed. This made it possible to form a further vector in terms of searching for biologically active structures among 1,2,4-triazole derivatives. The review develops a modern approach to the search for biologically active substances among 1,2,4-triazole derivatives. Sys- tematized data on the nature of substituents in the core of 1,2,4-triazole, which affect a specific type of activity.
The search material was selected over the past decade with the highest number of citations at the time of literature analysis.

Project Number

2

References

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There are 75 citations in total.

Details

Primary Language English
Subjects Pharmacology and Pharmaceutical Sciences
Journal Section Review Articles
Authors

Yurii Sameliuk

Andrii Kaplaushenko 0000-0001-8675-5081

Natalia Nedorezanıuk

Liusine Ostretsova

Feodosiia Diakova 0000-0003-3132-3497

Bogdan Gutyj 0000-0002-5971-8776

Project Number 2
Publication Date September 1, 2022
Acceptance Date March 30, 2022
Published in Issue Year 2022 Volume: 42 Issue: 3

Cite

Vancouver Sameliuk Y, Kaplaushenko A, Nedorezanıuk N, Ostretsova L, Diakova F, Gutyj B. Prospects for the search for new biologically active compounds among the derivatives of the heterocyclic system of 1,2,4-triazole. HUJPHARM. 2022;42(3):175-86.

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