Research Article
Year 2023,
Volume: 9 Issue: 2, 76 - 100, 31.08.2023
Abstract
Amaç: Bu çalışma, radyofrekans disk nükleoplastisinin (RFN), intervertebral disk dejenerasyonu ve disk herniasyonu üzerindeki etkilerini araştırmayı amaçlamaktadır.
Materyal ve Yöntemler: Çalışma, 27 adet erkek Yeni Zelanda Beyaz Tavşanı üzerinde gerçekleştirilmiştir. Hayvanlar farklı gruplara ayrılmış ve RFN uygulanmıştır. İşlem sırasında sıcaklık, enerji (joule), motor fonksiyonlar ve patolojik değişiklikler kaydedilmiştir.
Bulgular: Joule-Zaman İlişkisi: Saniyeler arttıkça uygulanan gücün arttığı gözlendi.
Sıcaklık-Zaman İlişkisi: Gruplar arasında sıcaklık ölçümleri değerlerinde anlamlı bir fark bulunmadı.
Joule-Sıcaklık İlişkisi: Uygulanan joule değerleri ile sıcaklık değerleri arasında anlamlı bir ilişki saptanmadı.
Motor-Zaman İlişkisi: Bazı gruplarda motor yanıt ortalama değerlerinde anlamlı farklar bulundu. Özellikle 2. cepçik uygulanan gruplarda uygulanan joule'un artığı ve sonuç olarak motor skor değerinin azaldığı gözlendi.
Patolojik Bulgular: Bazı gruplarda belirgin disk dejenerasyonu ve hafif-orta nöral kayıp gözlendi. Uygulanan joule değerleri ile patoloji skoru arasında anlamlı bir ilişki bulundu.
Sıcaklık-Patolojik Skor İlişkisi: Sıcaklık değerleri ile patoloji skoru arasında anlamlı bir ilişki saptanmadı.
Sonuç:Radyofrekans disk nükleoplastisinin intervertebral disk dokusuna etkileri detaylı bir şekilde incelenmiştir. Bu yöntem, bel ağrısının tedavisinde etkili bir araç olabileceğini göstermektedir, ancak daha kapsamlı araştırmaya ihtiyaç duyulmaktadır. Sonuç, uygulanan joule değerinin patolojik değişikliklerle ilişkili olduğunu, ancak sıcaklıkla doğrudan ilişkili olmadığını vurgulamaktadır.
Keywords
Radyofrekans Disk Nükleoplastisi İntervertebral Disk Dejenerasyonu Disk Herniasyonu Minimal İnvaziv Tedavi
References
- 1.Adams MA, Hutton WC. Prolapsed intervertebral disc: A hyperflexion injury. Spine 1982; 7: 184-191
- 2.Andersson GB, Brown MD, Dvorak J, et al. Consensus summary of the diagnosis and treatment of lumbar disc herniation. Spine 1996;21(24 suppl):75S–8.
- 3.Antoniou J, Steffen T, Nelson F. The human lumbar intervertebral disc- Evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing and degeneration. Journal of Clinical Investigation 1996; 98(4): 996-1003.
- 4.Bernick S, Walker JM, Paule WJ, et al: Age changes on the anulus fibrosus in human intervertebral discs. Spine 16: 520-524, 1991.
- 5.Buckwalter JA, Roughley PJ, Rosenberg LC. Age-related changes in cartilage proteoglicans-quantitative electron microscopic studies. Microscopy Research and Technique 1994; 28(5): 398-408. Chelberg MK, Banks GM, Geiger DF. Identification of heterogeneous cell-populations in normal human intervertebral disc. Journal of Anatomy 1995; 186: 43-53
- 6.Chen Y C, Lee S H and Chen D: Intradiscal pressure study of percutaneous disc decompression with nucleoplasty in human cadavers Spine 28 661–5, 2003.
- 7.Chen YC, Lee S, Saenz Y, Lehman NL: Histologic findings of disc, end plate and neural elements after coblation of nucleus pulposus: an experimental nucleoplasty study. The Spine Journal 3: 466–470, 2003.
- 8.Cohen SP, Larkin T, Abdi S, et al. Risk factors for failure and complica-tions of intradiscal electrothermal therapy: A pilot study. Spine 28: 1142-7, 2003.
- 9.Collins DH. The Pathology of Articular and Spinal Disease. Edward Arnold&Co. London 1949;256
- 10.Devor M: Pain arising from the nevre root and the dorsal root ganglion. In: Weinstein JN, Gordon SL: Low back pain. AAOS, Rosemont, 1996, pp 187-208.
- 11.Drummond JC, Moore SS: The influence of dextrose administration on neurlogic outcome after temporary spinal cord ischemia in the rabbit. Anesthesiology 70:64-70, 1989.
- 12.Goupille P, Jayson MI, Valat JP, et al: Matrix metalloproteinases: The clue to intervertebral disc degeneration? Spine 23: 612-626, 1998.
- 13.Grignon B, Grignon Y, Mainard D. The structure of the cartilaginous end-plates in elder people. Surgical and Radiologic Anatomy 2000; 22(1): 13-19
- 14.Gruber HE, Fisher EC, Desai B. Human intervertebral disc cells from the annulus: Three-dimensional culture in Experimental Cell Research 1997; 235(1): 13-21.
- 15.Iwatsuki K, Yoshimine T, Sasaki M, Yasuda K, Akiyama C, Nakahira R: The effect of laser irradiation for nucleus pulposus: an experimental study. Neurol Res. 27(3):319-23, 2005
- 16.Kambin P, Brager MD. Percutaneous posterolateral discectomy: anatomy and mechanism. Clin Orthop 1987;Oct(223):145–54.
- 17.Karasek M, Bogduk N. Twelve-month follow-up of a controlled trial of intradiscal thermal annuloplasty for back pain due to internal disc disruption. Spine 25: 2601-7, 2000.
- 18.Kleinstueck FS, Diederich CJ, Nau WH, et al. Temperature and thermal dose distributions during intradiscal electrothermal therapy in the cadaveric lumbar spine. Spine 28: 1700, 2003.
- 19.Lee J, Lutz GE, Campbell D. Stability of the lumbar spine after intradiscal elektrothermal therapy. Arch Phys Med Rehabil 82; 120-3, 2001.
- 20.Nau WN, Diederich CJ: Evaluation of temperature distributions in cadaveric lumbar spine during nucleoplasty. Phys. Med. Biol. 49: 1583–1594, 2004.
- 21.Nerubay J, Caspi I, Levinkopf M, Tadmor A and Bubis J J: Percutaneous laser nucleolysis of the intervertebral lumbar disc. An experimental study Clin. Orthop. 337: 42–4, 1997.
- 22.Nerubay J, Caspi I, Levinkopf M, Tadmor A, Bubis JJ. Percutaneous laser nucleolysis of the intervertebral lumbar disc: an experimental study. Clin Orthop Rel Res 1997;Apr(337):42–4.
- 23.Ohshima H, Urban JP: The effect of lactat and PH on proteoglycan and protein synthesis rates in the intervertebral disc. Spine 17: 1079-1082, 1992.
- 24.Pauza KJ, Howell S, Dreyfuss P, et al. A randomized, placebo-controlled trial of intradiscal electrothermal therapy for the treatment of discogenic low back pain. Spine J 4: 27-35, 2004.
- 25.Saal JA, Saal JS. Intradiscal electrothermal treatment (IDET) for chronic discogenic low back pain. A prospective outcome study with minimum one year follow-up. Spine 25: 2622-7, 2000.
- 26.Saal JA, Saal JS. Intradiscal electrothermal treatment for chronic dis-cogenic low back pain. Prospective outcome study with a minimum 2- year follow-up. Spine 27: 966-74, 2002.
- 27.Sasaki M, Takahashi T, Miyahara K, Hirose T. Effects of chondroitinase ABC on intradiscal pressure in sheep: an in vivo study. Spine 2001;26(5):463–8.
- 28.Schwartzer AC, Aprill CN, Derby R, et al. The prevelance and clinical features of internal disc disruption in patients with chronic low back pain. Spine 20: 1878-83, 1995.
- 29.Sharps LS, Isaac Z. Percutaneous disc decompression using nucleo-plasty. Pain Physician. 5: 121-6, 2002.
- 30.Singh V, Piryani C, Liao K, Niesculz S. Percutaneous disc decompresiion using coblation (nucleoplasty) in the treatment of chronic discogenic pain. Pain Physician 5: 250-9, 2002.
- 31.Wilberger JE, Bost JW, Maroon JC. Ambulatory surgery is safe and effective in radicular disc disease. Spine 1995;20(7):861–2.
Year 2023,
Volume: 9 Issue: 2, 76 - 100, 31.08.2023
Abstract
References
- 1.Adams MA, Hutton WC. Prolapsed intervertebral disc: A hyperflexion injury. Spine 1982; 7: 184-191
- 2.Andersson GB, Brown MD, Dvorak J, et al. Consensus summary of the diagnosis and treatment of lumbar disc herniation. Spine 1996;21(24 suppl):75S–8.
- 3.Antoniou J, Steffen T, Nelson F. The human lumbar intervertebral disc- Evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing and degeneration. Journal of Clinical Investigation 1996; 98(4): 996-1003.
- 4.Bernick S, Walker JM, Paule WJ, et al: Age changes on the anulus fibrosus in human intervertebral discs. Spine 16: 520-524, 1991.
- 5.Buckwalter JA, Roughley PJ, Rosenberg LC. Age-related changes in cartilage proteoglicans-quantitative electron microscopic studies. Microscopy Research and Technique 1994; 28(5): 398-408. Chelberg MK, Banks GM, Geiger DF. Identification of heterogeneous cell-populations in normal human intervertebral disc. Journal of Anatomy 1995; 186: 43-53
- 6.Chen Y C, Lee S H and Chen D: Intradiscal pressure study of percutaneous disc decompression with nucleoplasty in human cadavers Spine 28 661–5, 2003.
- 7.Chen YC, Lee S, Saenz Y, Lehman NL: Histologic findings of disc, end plate and neural elements after coblation of nucleus pulposus: an experimental nucleoplasty study. The Spine Journal 3: 466–470, 2003.
- 8.Cohen SP, Larkin T, Abdi S, et al. Risk factors for failure and complica-tions of intradiscal electrothermal therapy: A pilot study. Spine 28: 1142-7, 2003.
- 9.Collins DH. The Pathology of Articular and Spinal Disease. Edward Arnold&Co. London 1949;256
- 10.Devor M: Pain arising from the nevre root and the dorsal root ganglion. In: Weinstein JN, Gordon SL: Low back pain. AAOS, Rosemont, 1996, pp 187-208.
- 11.Drummond JC, Moore SS: The influence of dextrose administration on neurlogic outcome after temporary spinal cord ischemia in the rabbit. Anesthesiology 70:64-70, 1989.
- 12.Goupille P, Jayson MI, Valat JP, et al: Matrix metalloproteinases: The clue to intervertebral disc degeneration? Spine 23: 612-626, 1998.
- 13.Grignon B, Grignon Y, Mainard D. The structure of the cartilaginous end-plates in elder people. Surgical and Radiologic Anatomy 2000; 22(1): 13-19
- 14.Gruber HE, Fisher EC, Desai B. Human intervertebral disc cells from the annulus: Three-dimensional culture in Experimental Cell Research 1997; 235(1): 13-21.
- 15.Iwatsuki K, Yoshimine T, Sasaki M, Yasuda K, Akiyama C, Nakahira R: The effect of laser irradiation for nucleus pulposus: an experimental study. Neurol Res. 27(3):319-23, 2005
- 16.Kambin P, Brager MD. Percutaneous posterolateral discectomy: anatomy and mechanism. Clin Orthop 1987;Oct(223):145–54.
- 17.Karasek M, Bogduk N. Twelve-month follow-up of a controlled trial of intradiscal thermal annuloplasty for back pain due to internal disc disruption. Spine 25: 2601-7, 2000.
- 18.Kleinstueck FS, Diederich CJ, Nau WH, et al. Temperature and thermal dose distributions during intradiscal electrothermal therapy in the cadaveric lumbar spine. Spine 28: 1700, 2003.
- 19.Lee J, Lutz GE, Campbell D. Stability of the lumbar spine after intradiscal elektrothermal therapy. Arch Phys Med Rehabil 82; 120-3, 2001.
- 20.Nau WN, Diederich CJ: Evaluation of temperature distributions in cadaveric lumbar spine during nucleoplasty. Phys. Med. Biol. 49: 1583–1594, 2004.
- 21.Nerubay J, Caspi I, Levinkopf M, Tadmor A and Bubis J J: Percutaneous laser nucleolysis of the intervertebral lumbar disc. An experimental study Clin. Orthop. 337: 42–4, 1997.
- 22.Nerubay J, Caspi I, Levinkopf M, Tadmor A, Bubis JJ. Percutaneous laser nucleolysis of the intervertebral lumbar disc: an experimental study. Clin Orthop Rel Res 1997;Apr(337):42–4.
- 23.Ohshima H, Urban JP: The effect of lactat and PH on proteoglycan and protein synthesis rates in the intervertebral disc. Spine 17: 1079-1082, 1992.
- 24.Pauza KJ, Howell S, Dreyfuss P, et al. A randomized, placebo-controlled trial of intradiscal electrothermal therapy for the treatment of discogenic low back pain. Spine J 4: 27-35, 2004.
- 25.Saal JA, Saal JS. Intradiscal electrothermal treatment (IDET) for chronic discogenic low back pain. A prospective outcome study with minimum one year follow-up. Spine 25: 2622-7, 2000.
- 26.Saal JA, Saal JS. Intradiscal electrothermal treatment for chronic dis-cogenic low back pain. Prospective outcome study with a minimum 2- year follow-up. Spine 27: 966-74, 2002.
- 27.Sasaki M, Takahashi T, Miyahara K, Hirose T. Effects of chondroitinase ABC on intradiscal pressure in sheep: an in vivo study. Spine 2001;26(5):463–8.
- 28.Schwartzer AC, Aprill CN, Derby R, et al. The prevelance and clinical features of internal disc disruption in patients with chronic low back pain. Spine 20: 1878-83, 1995.
- 29.Sharps LS, Isaac Z. Percutaneous disc decompression using nucleo-plasty. Pain Physician. 5: 121-6, 2002.
- 30.Singh V, Piryani C, Liao K, Niesculz S. Percutaneous disc decompresiion using coblation (nucleoplasty) in the treatment of chronic discogenic pain. Pain Physician 5: 250-9, 2002.
- 31.Wilberger JE, Bost JW, Maroon JC. Ambulatory surgery is safe and effective in radicular disc disease. Spine 1995;20(7):861–2.
There are 31 citations in total.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Brain and Nerve Surgery (Neurosurgery) |
| Journal Section | Research Article |
| Authors | |
| Publication Date | August 31, 2023 |
| Published in Issue | Year 2023 Volume: 9 Issue: 2 |
International Anatolia Academic Online Journal Health Sciences