Traditional uses, phytochemistry, and toxic potential of Teucrium polium L.: A comprehensive review

Arzuhan Sıhoglu Tepe; Mehmet Ozaslan; Ibrahım Halil Kılıc; Sibel Bayıl Oguzkan

Review Article

Year 2021, Volume: 1 Issue: 1, 1 - 41, 15.12.2021

Arzuhan Sıhoglu Tepe Mehmet Ozaslan Ibrahım Halil Kılıc Sibel Bayıl Oguzkan

Abstract

References

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Traditional uses, phytochemistry, and toxic potential of Teucrium polium L.: A comprehensive review

Year 2021, Volume: 1 Issue: 1, 1 - 41, 15.12.2021

Arzuhan Sıhoglu Tepe Mehmet Ozaslan Ibrahım Halil Kılıc Sibel Bayıl Oguzkan

Abstract

The aim of this study was to present information about the traditional use and phytochemistry of T. polium, to discuss contradictory views about chemotaxonomy and its toxic effect on liver and kidneys, and to make suggestions about controversial areas and gaps in the literature. Literature data showed that T. polium has toxic effect on kidney tissue. Moreover, in some of the studies on the liver and in all clinical reports, T. polium has also been proven to have toxic effect on the liver. The components responsible for toxicity are thought to be neo-clerodane diterpenoids. However, it has been reported that flavonoids and some polyphenols in the plant also show antioxidant and anti-inflammatory effects. It has been concluded that more attention should be paid to the use of this plant. More clinical studies are needed to better understand the effects of T. polium on the liver. The effects of the plant on blood serum parameters and histological changes on the liver tissue should be documented in more detail. It was also concluded that that regular consumption of T. polium should be avoided for long periods of time.

Keywords

Teucrium polium, Ethnopharmacology, Phytochemistry, Toxicity, Kidney, Liver

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Primary Language	English
Subjects	Pharmacology and Pharmaceutical Sciences
Journal Section	Reviews
Authors	Arzuhan Sıhoglu Tepe 0000-0001-8290-9880 Mehmet Ozaslan This is me 0000-0001-9380-4902 Ibrahım Halil Kılıc This is me 0000-0002-0272-5131 Sibel Bayıl Oguzkan This is me 0000-0003-0254-6915
Publication Date	December 15, 2021
Submission Date	June 24, 2021
Published in Issue	Year 2021 Volume: 1 Issue: 1

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APA	Sıhoglu Tepe, A., Ozaslan, M., Kılıc, I. H., Bayıl Oguzkan, S. (2021). Traditional uses, phytochemistry, and toxic potential of Teucrium polium L.: A comprehensive review. International Journal of Plant Based Pharmaceuticals, 1(1), 1-41.
AMA	Sıhoglu Tepe A, Ozaslan M, Kılıc IH, Bayıl Oguzkan S. Traditional uses, phytochemistry, and toxic potential of Teucrium polium L.: A comprehensive review. Int. J. Plant Bas. Pharm. December 2021;1(1):1-41.
Chicago	Sıhoglu Tepe, Arzuhan, Mehmet Ozaslan, Ibrahım Halil Kılıc, and Sibel Bayıl Oguzkan. “Traditional Uses, Phytochemistry, and Toxic Potential of Teucrium Polium L.: A Comprehensive Review”. International Journal of Plant Based Pharmaceuticals 1, no. 1 (December 2021): 1-41.
EndNote	Sıhoglu Tepe A, Ozaslan M, Kılıc IH, Bayıl Oguzkan S (December 1, 2021) Traditional uses, phytochemistry, and toxic potential of Teucrium polium L.: A comprehensive review. International Journal of Plant Based Pharmaceuticals 1 1 1–41.
IEEE	A. Sıhoglu Tepe, M. Ozaslan, I. H. Kılıc, and S. Bayıl Oguzkan, “Traditional uses, phytochemistry, and toxic potential of Teucrium polium L.: A comprehensive review”, Int. J. Plant Bas. Pharm., vol. 1, no. 1, pp. 1–41, 2021.
ISNAD	Sıhoglu Tepe, Arzuhan et al. “Traditional Uses, Phytochemistry, and Toxic Potential of Teucrium Polium L.: A Comprehensive Review”. International Journal of Plant Based Pharmaceuticals 1/1 (December 2021), 1-41.
JAMA	Sıhoglu Tepe A, Ozaslan M, Kılıc IH, Bayıl Oguzkan S. Traditional uses, phytochemistry, and toxic potential of Teucrium polium L.: A comprehensive review. Int. J. Plant Bas. Pharm. 2021;1:1–41.
MLA	Sıhoglu Tepe, Arzuhan et al. “Traditional Uses, Phytochemistry, and Toxic Potential of Teucrium Polium L.: A Comprehensive Review”. International Journal of Plant Based Pharmaceuticals, vol. 1, no. 1, 2021, pp. 1-41.
Vancouver	Sıhoglu Tepe A, Ozaslan M, Kılıc IH, Bayıl Oguzkan S. Traditional uses, phytochemistry, and toxic potential of Teucrium polium L.: A comprehensive review. Int. J. Plant Bas. Pharm. 2021;1(1):1-41.

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