Abstract
Vulvanın meme benzeri karsinomlarının ektopik meme dokusundan kaynaklandığı veya meme karsinomu metastazı olduğu düşünülmüştür. Ancak, şu anda, vulvada meme-benzeri bezler olduğu için, memede görülen herhangi bir patolojinin bu bezlerde görülebileceği kabul edilmektedir. Vulvanın adenokarsinomu nadir olup, meme-benzeri adenokarsinomları literatürde olgu sunumları şeklinde yer almaktadır. Vulvar kitle ve kanama şikayetiyle başvuran 70 yaşındaki hastada tanımladığımız vulvanın primer meme benzeri karsinomu olgusunu sunuyoruz. İnsizyonel biyopsi vulvar adenokarsinom olarak raporlandı. İntraoperatif sentinal lenf düğümü incelemesi adenokarsinom metastazı olan hastaya hemivulvektomi ve bilateral inguinal lenfadenektomi uygulandı. Vulvanın adenokarsinomları nadir olup, prognoz ve tedavi primer meme kanseri ile benzerlik gösterdiği için bu olgularda meme benzeri karsinom akılda tutulmalıdır.
Keywords
References
- Kazakov DV, Spagnolo DV, Kacerovska D, Michal M. Lesions of anogenital mammary-like glands: An update. Adv Anat Pathol 2011; 18: 1-28.
- Cho D, Buscema J, Rosenshein NB, Woodruff JD. Primary breast cancer of the vulva. Obstet Gynecol 1985; 66: 79-81.
- Di Bonito L, Patriarca S, Falconieri G. Aggressive “breastlike” adenocarcinoma of vulva. Pathol Res Pract 1992; 188: 211-4.
- Ohira S, Itoh K, Osada K, Oka K, Suzuki A, Osada R. Vulvar Paget’s disease with underlying adenocarcinoma simulating breast carcinoma: Case report and review of the literature. Int J Gynecol Cancer 2004; 14: 1012-7. van der Putte SC. Anogenital “sweat” glands. Histology and pathology of a gland that may mimic mammary glands. Am J Dermatopathol 1991; 13: 557-67. van der Putte SC. Mammary-like glands of the vulva and their disorders. Int J Gynecol Pathol 1994; 13: 150-60.
- Tseung J, Russell P. “Breast-like” lesions in the vulva: histology, origin and significance. Pathology 2008; 40: 321-6.
- Bailey CL, Sankey HZ, Donovan JT. Primary breast cancer of the vulva. Gynecol Oncol 1993; 50: 379-83.
- Fracchioli S, Puopolo M, De La Longrais IA, Scozzafava M, Bogliatto F, Arisio R. Primary “breast-like” cancer of the vulva: A case report and critical review of the literature. Int J Gynecol Cancer. 2006; 16: 423-8.
- Tanaka H, Umekawa T, Nagao K, Ishihara A, Toyoda N. Adenocarcinoma of mammary-like glands in the vulva successfully treated by weekly paclitaxel. Int J Gynecol Cancer 2005; 15: 568-71.
- Martinez-Palones JM, Perez-Benavente A, Diaz-Feijoo B, Gil-Moreno A, Roca I, García-Jimenez A. Sentinel lymph node identification in a primary ductal carcinoma arising in the vulva. Int J Gynecol Cancer 2007; 17: 471-7.
- Lopes G, DeCesare T, Ghurani G. Primary ectopic breast cancer presenting as a vulvar mass. Clin Breast Cancer 2006; 7: 278-9.
- Wilkinson EJ. Premalignant and Malignant tumors of the vulva. In Kurman RJ, Zaino RJ, Norris HJ. Blaustein’s Pathology of The Female Genital Tract 6th edition. New York, Springer-Verlag 2010; 89.
- Irvin WP, Cathro HP, Grosh WW, Rice LW, Andersen WA. Primary breast carcinoma of the vulva: A case report and literature review. Gynecol Oncol 1999; 73: 155-9.
- Levin M, Pakarakas RM, Chang HA, Maiman M, Goldberg SL. Primary breast carcinoma of the vulva: A case report and review of the literature. Gynecol Oncol 1995; 56: 448-51.
- Abbott JJ, Ahmed I. Adenocarcinoma of mammary-like glands of the vulva: Report of a case and review of the literature. Am J Dermatopathol 2006; 28: 127 van der Putte SC, van Gorp LH. Adenocarcinoma of the mammary-like glands of the vulva: A concept unifying sweat gland carcinoma of the vulva, carcinoma of super numerary mammary glands and extra mammary Paget’s disease. Cutan Pathol 1994; 21: 157-63.
Invasive ductal carcinoma of the mammary like glands of vulva-with sentinel lymph node identification
Abstract
Abstract
Breast like carcinomas of the vulva was thought to be originated from ectopic breast tissue or metastasis from breast. It is now accepted that, as mammary-like glands are present in the vulva, any pathology that is found in the breast can be seen at these glands. Adenocarcinoma of the vulva is rare and the breast-like adenocarcinomas are presented as case reports in the literature. We present a primary breast-like carcinoma of the vulva in a 70 year old patient, who had complaint of vulvar mass and bleeding from it. The incisional biopsy was reported as vulvar adenocarcinoma. The intraoperative diagnosis of sentinel lymph node was adenocarcinoma metastasis and hemivulvectomy together with bilateral inguinal lymphadenectomy was carried out. Adenocarcinomas of vulva are very rare and breast like carcinoma must be kept in mind in these cases, as the prognosis and treatment is similar to primary breast carcinomas.
Keywords: Vulva, vulvar neoplasms, breast, carcinoma, ductal
Özet
Vulvanın meme benzeri karsinomlarının ektopik meme dokusundan kaynaklandığı veya meme karsinomu metastazı olduğu düşünülmüştür. Ancak, şu anda, vulvada meme-benzeri bezler olduğu için, memede görülen herhangi bir patolojinin bu bezlerde görülebileceği kabul edilmektedir. Vulvanın adenokarsinomu nadir olup, meme-benzeri adenokarsinomları literatürde olgu sunumları şeklinde yer almaktadır. Vulvar kitle ve kanama şikayetiyle başvuran 70 yaşındaki hastada tanımladığımız vulvanın primer meme benzeri karsinomu olgusunu sunuyoruz. İnsizyonel biyopsi vulvar adenokarsinom olarak raporlandı. İntraoperatif sentinal lenf düğümü incelemesi adenokarsinom metastazı olan hastaya hemivulvektomi ve bilateral inguinal lenfadenektomi uygulandı. Vulvanın adenokarsinomları nadir olup, prognoz ve tedavi primer meme kanseri ile benzerlik gösterdiği için bu olgularda meme benzeri karsinom akılda tutulmalıdır.
Anahtar sözcükler: Vulva, vulvar tümörler, meme, karsinoma, duktalKeywords
References
- Kazakov DV, Spagnolo DV, Kacerovska D, Michal M. Lesions of anogenital mammary-like glands: An update. Adv Anat Pathol 2011; 18: 1-28.
- Cho D, Buscema J, Rosenshein NB, Woodruff JD. Primary breast cancer of the vulva. Obstet Gynecol 1985; 66: 79-81.
- Di Bonito L, Patriarca S, Falconieri G. Aggressive “breastlike” adenocarcinoma of vulva. Pathol Res Pract 1992; 188: 211-4.
- Ohira S, Itoh K, Osada K, Oka K, Suzuki A, Osada R. Vulvar Paget’s disease with underlying adenocarcinoma simulating breast carcinoma: Case report and review of the literature. Int J Gynecol Cancer 2004; 14: 1012-7. van der Putte SC. Anogenital “sweat” glands. Histology and pathology of a gland that may mimic mammary glands. Am J Dermatopathol 1991; 13: 557-67. van der Putte SC. Mammary-like glands of the vulva and their disorders. Int J Gynecol Pathol 1994; 13: 150-60.
- Tseung J, Russell P. “Breast-like” lesions in the vulva: histology, origin and significance. Pathology 2008; 40: 321-6.
- Bailey CL, Sankey HZ, Donovan JT. Primary breast cancer of the vulva. Gynecol Oncol 1993; 50: 379-83.
- Fracchioli S, Puopolo M, De La Longrais IA, Scozzafava M, Bogliatto F, Arisio R. Primary “breast-like” cancer of the vulva: A case report and critical review of the literature. Int J Gynecol Cancer. 2006; 16: 423-8.
- Tanaka H, Umekawa T, Nagao K, Ishihara A, Toyoda N. Adenocarcinoma of mammary-like glands in the vulva successfully treated by weekly paclitaxel. Int J Gynecol Cancer 2005; 15: 568-71.
- Martinez-Palones JM, Perez-Benavente A, Diaz-Feijoo B, Gil-Moreno A, Roca I, García-Jimenez A. Sentinel lymph node identification in a primary ductal carcinoma arising in the vulva. Int J Gynecol Cancer 2007; 17: 471-7.
- Lopes G, DeCesare T, Ghurani G. Primary ectopic breast cancer presenting as a vulvar mass. Clin Breast Cancer 2006; 7: 278-9.
- Wilkinson EJ. Premalignant and Malignant tumors of the vulva. In Kurman RJ, Zaino RJ, Norris HJ. Blaustein’s Pathology of The Female Genital Tract 6th edition. New York, Springer-Verlag 2010; 89.
- Irvin WP, Cathro HP, Grosh WW, Rice LW, Andersen WA. Primary breast carcinoma of the vulva: A case report and literature review. Gynecol Oncol 1999; 73: 155-9.
- Levin M, Pakarakas RM, Chang HA, Maiman M, Goldberg SL. Primary breast carcinoma of the vulva: A case report and review of the literature. Gynecol Oncol 1995; 56: 448-51.
- Abbott JJ, Ahmed I. Adenocarcinoma of mammary-like glands of the vulva: Report of a case and review of the literature. Am J Dermatopathol 2006; 28: 127 van der Putte SC, van Gorp LH. Adenocarcinoma of the mammary-like glands of the vulva: A concept unifying sweat gland carcinoma of the vulva, carcinoma of super numerary mammary glands and extra mammary Paget’s disease. Cutan Pathol 1994; 21: 157-63.
Details
| Primary Language | English |
|---|---|
| Journal Section | Case Reports |
| Authors | |
| Publication Date | February 14, 2014 |
| Published in Issue | Year 2013Volume 35, Issue 4 (2013): Supplement |