Abstract
Objective: Even though the colorectal cancer is less common in young patients, it has a worse prognosis. The incidence of colorectal cancer in this age group is increasing in recent years. In this study we investigated young patients with colorectal cancer, whose follow-ups and treatments were performed in our clinic, according to the literature. Method: In our clinic the records of 39 patients under 40 years of age were examined between January 2005 and September 2013 retrospectively. Age and gender of the patients, tumor localizations, the shape of the operation and the tumor pathological features were recorded. Results: 19 patients (48.7%) were female, 20 (51.3%) were male and mean age was 32.6 years. 34 patients (87.2%) operated electively and 5 patients (12.8%) had emergency surgery. The localization of the tumor was mostly in the rectum (41.0%, n = 16). For 13 (33.3%) patients, who have the tumor localized in the right column, right hemicolectomy was performed. For patients, who have the tumor localized in the rectum, mostly low anterior resection was performed and totally for 7 patients, a stoma was opened. Pathological investigation revealed mucinous adenocarcinoma in 17 (43.6%) patients. Conclusion: Rectal cancer is more common in young patients with colorectal cancer and is often diagnosed at an advanced stage. Therefore in this patient group, complaints, which cause suspicion of colorectal cancer, should be examined carefully and advanced inspection methods should be performed
Keywords
References
- Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ. Cancer statistics. CA Cancer J Clin 2008; 58: 71-96.
- O’Connell JB, Maggard MA, Liu JH, Etzioni DA, Livingston EH, Ko CY. Do young colon cancer patients has worse outcomes? World J Surg 2004; 28: 558-62.
- Keswani SG, Boyle MJ, Maxwell JP 4th, Mains L, Wilks SM, Hunt JP, O'Leary JP. Colorectal cancer in patients younger than 40 years of age. Am Surg 2002; 68: 871-6.
- Umpleby HC, Williamson RC. Carcinoma of the large bowel in the first four decades. Br J Surg 1984; 71: 272-7.
- Chung YF, Eu KW, Machin D, Ho JM, Nyam DC, Leong AF, Ho YH, Seow-Choen F. Young age is not a poor colorectal cancer. Br J Surg 1998; 85: 1255-9. marker in
- Adloff M, Arnaud JP, Schloegel M, Thibaud D, Bergamaschi R. Colorectal cancer in patients under 40 years of age. Dis Colon Rectum 1986; 29: 322-5.
- O'Connell JB, Maggard MA, Liu JH, Etzioni DA, Livingston EH, Ko CY. Rates of colon and rectal cancers are increasing in young adults. Am Surg 2003; 69: 866-72.
- O'Connell JB, Maggard MA, Livingston EH, Yo CK. Colorectal cancer in the young. Am J Surg 2004; 187: 343-8.
- Shemesh-Bar L, Idelevich E, Sulkes J, Sulkes A, Brenner B. Colorectal cancer in young patients in Israel: A distinct clinicopathological entity? World J Surg 2010; 34: 2701-9. Y,
- Berut M, Mik M, Kędzia-Berut R, Kujawski R, Trzciński R, Dziki Ł, Dziki A. Colorectal cancer in young and elderly patients. Pol Przegl Chir 2013; 85: 446-51.
- Ben-Ishay O, Brauner E, Peled Z, Othman A, Person B, Kluger Y. Diagnosis of colon cancer differs in younger versus older patients despite similar complaints. Isr Med Assoc J 2013; 15: 284-7.
- Minardi AJ Jr, Sittiq KM, Zibari GB, McDonald JC. Colorectal cancer in the young patient. Am Surg 1998; 64: 849-53.
- Leff DR, Chen A, Roberts D, Grant K, Western C, Windsor AC, Cohen CR. Colorectal Cancer in the Young Patient. Am Surg 2007; 73: 42-7.
- D'Onofrio GM, Tan EG. Is colorectal carcinoma in the young a more deadly disease? Aust N Z J Surg 1985; 55: 537-40.
- Zbuk K, Sidebotham EL, Bleyer A, La Quaglia MP: Colorectal cancer in young adults. Semin Oncol 200936: 439-50.
Abstract
SUMMARY
Objective: Even though the colorectal cancer is less common in young patients, it has a worse prognosis. The incidence of colorectal cancer in this age group is increasing in recent years. In this study we investigated young patients with colorectal cancer, whose follow-ups and treatments were performed in our clinic, according to the literature. Method: In our clinic the records of 39 patients under 40 years of age were examined between January 2005 and September 2013 retrospectively. Age and gender of the patients, tumor localizations, the shape of the operation and the tumor pathological features were recorded. Results: 19 patients (48.7%) were female, 20 (51.3%) were male and mean age was 32.6 (19-39) years. 34 patients (87.2%) operated electively and 5 patients (12.8%) had emergency surgery. The localization of the tumor was mostly in the rectum (41.0%, n = 16). For 13 (33.3%) patients, who have the tumor localized in the right column, right hemicolectomy was performed. For patients, who have the tumor localized in the rectum, mostly low anterior resection was performed and totally for 7 patients, a stoma was opened. Pathological investigation revealed mucinous adenocarcinoma in 17 (43.6%) patients. Conclusion: Rectal cancer is more common in young patients with colorectal cancer and is often diagnosed at an advanced stage. Therefore in this patient group, complaints, which cause suspicion of colorectal cancer, should be examined carefully and advanced inspection methods should be performed.
Keywords: Colorectal cancer, young patient
ÖZET
Amaç: Genç hastalarda kolorektal kanserler genel popülasyona göre daha az görülmesine rağmen daha kötü prognoza sahiptir. Son yıllar içerisinde bu yaş grubunda kolorektal kanserlerin görülme sıklığı artmaktadır. Biz bu çalışmada kliniğimizde takip ve tedavisi yapılan genç kolorektal kanserli hastaların özelliklerini ve sonuçlarımızı literatür ışığında nceledik. Yöntem: Kliniğimizde Ocak 2005-Eylül 2013 tarihleri arasında 40 yaş altındaki 39 hastanın kayıtları retrospektif olarak incelendi. Bu hastaların yaşı, cinsiyeti, tümörün yerleşim yeri, operasyonun şekli ve tümörün patolojik özellikleri kaydedildi. Bulgular: Hastaların 19’u (%48,7) kadın, 20’si (%51,3) erkek ve ortalama yaş 32,6 (19-39) idi. Otuzdördü (%87,2) elektif, 5’i (%12,8) acil opere edilmişti. Tümör en fazla rektumda yerleşik idi (%41,0; n=16). Tümörün sağ kolonda olduğu 13 (%33,3) hastanın tamamına sağ hemikolektomi, rektumda yerleşen tümörlere de en fazla low anterior rezeksiyon uygulanmış, toplam 7 hastaya stoma açılmıştı. Patolojik inceleme sonucunda 17 (%43,6) hastada müsinöz adenokarsinom görüldü. Sonuç: Genç kolorektal kanserli hastalarda rektum kanserleri daha sık görülmekte ve genellikle ileri evrede tanı konulmaktadır. Bu nedenle bu hasta grubunda kolorektal kanser şüphesi uyandıran şikayetler titizlikle irdelenmeli ve ileri tetkik yöntemlerine başvurulmalıdır.
Anahtar sözcükler: Genç hasta, kolorektal kanser
Keywords
References
- Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ. Cancer statistics. CA Cancer J Clin 2008; 58: 71-96.
- O’Connell JB, Maggard MA, Liu JH, Etzioni DA, Livingston EH, Ko CY. Do young colon cancer patients has worse outcomes? World J Surg 2004; 28: 558-62.
- Keswani SG, Boyle MJ, Maxwell JP 4th, Mains L, Wilks SM, Hunt JP, O'Leary JP. Colorectal cancer in patients younger than 40 years of age. Am Surg 2002; 68: 871-6.
- Umpleby HC, Williamson RC. Carcinoma of the large bowel in the first four decades. Br J Surg 1984; 71: 272-7.
- Chung YF, Eu KW, Machin D, Ho JM, Nyam DC, Leong AF, Ho YH, Seow-Choen F. Young age is not a poor colorectal cancer. Br J Surg 1998; 85: 1255-9. marker in
- Adloff M, Arnaud JP, Schloegel M, Thibaud D, Bergamaschi R. Colorectal cancer in patients under 40 years of age. Dis Colon Rectum 1986; 29: 322-5.
- O'Connell JB, Maggard MA, Liu JH, Etzioni DA, Livingston EH, Ko CY. Rates of colon and rectal cancers are increasing in young adults. Am Surg 2003; 69: 866-72.
- O'Connell JB, Maggard MA, Livingston EH, Yo CK. Colorectal cancer in the young. Am J Surg 2004; 187: 343-8.
- Shemesh-Bar L, Idelevich E, Sulkes J, Sulkes A, Brenner B. Colorectal cancer in young patients in Israel: A distinct clinicopathological entity? World J Surg 2010; 34: 2701-9. Y,
- Berut M, Mik M, Kędzia-Berut R, Kujawski R, Trzciński R, Dziki Ł, Dziki A. Colorectal cancer in young and elderly patients. Pol Przegl Chir 2013; 85: 446-51.
- Ben-Ishay O, Brauner E, Peled Z, Othman A, Person B, Kluger Y. Diagnosis of colon cancer differs in younger versus older patients despite similar complaints. Isr Med Assoc J 2013; 15: 284-7.
- Minardi AJ Jr, Sittiq KM, Zibari GB, McDonald JC. Colorectal cancer in the young patient. Am Surg 1998; 64: 849-53.
- Leff DR, Chen A, Roberts D, Grant K, Western C, Windsor AC, Cohen CR. Colorectal Cancer in the Young Patient. Am Surg 2007; 73: 42-7.
- D'Onofrio GM, Tan EG. Is colorectal carcinoma in the young a more deadly disease? Aust N Z J Surg 1985; 55: 537-40.
- Zbuk K, Sidebotham EL, Bleyer A, La Quaglia MP: Colorectal cancer in young adults. Semin Oncol 200936: 439-50.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Surgical Science Research Articles |
| Authors | |
| Publication Date | March 27, 2015 |
| Published in Issue | Year 2015Volume: 37 Issue: 1 |