The factors that effect in vitro fertilization success in women of critical ages: “38-40 years”

Ziya Kalem; Coşkun Şimşir; Turgut Var

doi:10.7197/223.vi.532805

EN

The factors that effect in vitro fertilization success in women of critical ages: “38-40 years”

Abstract

Objective: The aim of this study is to assess the factors that affect IVF success in women of critical ages of “38-40 years”.

Method: 468 women aged 38-40 years who were admitted for IVF between January 2013 to December 2017 were enrolled in the study. Ovarian stimulation characteristics, number of oocytes retrieved, number of embryos transferred and pregnancy rates ,cancellation rate ,live birth rate were analyzed.

Results: The overall clinical pregnancy rate was 17.9% . Cancellation rate was 22.4%. The miscarriage rate was 25% (21/84).The live birth rate was 13.4% (63/468).Comparing the patients who did and did not achieve conception, we found statistically meaningful differences in terms of antral follicular count, retrieved oocyte count, number of embryos obtained, embryo count that was transferred,. Logistic regression analysis showed that the following factors were significantly related to higher pregnancy rates: number of embryos transferred, HMG usage in the stimulation protocol, basal FSH and blastocyst transfer.

Conclusions: The most important parameters which predict pregnancy in 38-40 year-old women are the transfer of a high number of embryos, HMG usage in the stimulation protocol, low basal FSH level and blastocyst transfer.

Keywords

Women’s age,IVF outcome,pregnancy rate

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Ziya Kalem ^*
0000-0002-5435-2074
Türkiye

Coşkun Şimşir
0000-0003-1825-6584
Türkiye

Turgut Var
0000-0002-4479-1399
Türkiye

Publication Date

March 28, 2019

Submission Date

February 27, 2019

Acceptance Date

March 26, 2019

Published in Issue

Year 1970 Volume: 41 Number: 1

DOI

https://doi.org/10.7197/223.vi.532805

IZ

https://izlik.org/JA84JG92MS

Cite

RIS / Bibtex

AMA

1.Kalem Z, Şimşir C, Var T. The factors that effect in vitro fertilization success in women of critical ages: “38-40 years.” CMJ. 2019;41(1):223-229. doi:10.7197/223.vi.532805

Öz

The factors that effect in vitro fertilization success in women of critical ages: “38-40 years”

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite