Utilization avenues for induced pluripotent stem cells in autism
Abstract
Objective: Autism spectrum disorder (ASD) is a neurodevelopmental difference with increasing global prevalence. Yet, the etiology of ASD is still not unraveled. Individuals with ASD experience difficulties with social skills and communication, and exhibit repetitive and restrictive interests and behaviors.
Method: There is yet no comprehensive model of autism that can explain all aspects of autism. Similarly, there exists no known treatment for it. Induced pluripotent stem cell (iPSC), which has been widely used in the regenerative treatment of many diseases in recent years, is promising for a better understanding of the causes of autism.
Results: Autism modelling with iPSCs provides several opportunities for understanding the mechanisms underlying autism and developing personalized treatments.
Conclusions: This review examines the use of iPSCs in ASD to date, their advantages, and the findings obtained via iPSC modeling of autism.
Keywords
References
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Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Review
Publication Date
March 28, 2019
Submission Date
March 22, 2019
Acceptance Date
March 27, 2019
Published in Issue
Year 1970 Volume: 41 Number: 1