Clinical Research
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Gebelikten önce COVID-19 geçirenlerde ilk trimester uterine arter direnci, plasental volüm ve gebelik sonuçlarının incelenmesi

Year 2023, Volume: 20 Issue: 3, 1894 - 1898, 01.10.2023
https://doi.org/10.38136/jgon.1345235

Abstract

Amaç: Gebelikte geçirilen Koronavirüs hastalığı 2019 (COVID-19) vasküler hasar yaratarak ve uterin kanlanmayı etkliyerek gebelik sonuçlarını kötüleştirdiğine dair çalışmalar mevcuttur. Bu çalışmada COVID-19 geçirdikten sonra gebe kalanlarda ilk trimester plasenta gelişimini ve gebelik sonuçlarını değerlendirerek ve COVID-19 etkisinin kalıcılığını araştırdık.
Gereçler ve Yöntem: Bu prospektif çalışma, gebeliğinden bir yıl öncesine kadar COVID-19 maruziyeti olan gebeler ile sağlıklı gebe kontrol grubundaki plasental hacim ve uterin arter Doppler akım ölçümleri arasındaki farklılıkları değerlendirmektedir.
Bulgular: Yaş, doğum oranı ve vücut kitle indeksi gibi demografik özelliklerin, 50 hasta ve 50 kontrol üzerinde yapılan bu çalışmada benzer olduğu görüldü. Oligohidramniyoz, prematürite, preeklampsi ve intrauterin büyüme geriliği gibi çeşitli sonuçlar incelendiğinde; bu verilerde istatistiksel olarak anlamlı olmayan hafif varyasyonlar dikkat çekti. Doğum ağırlığı ve 1. dakika Apgar skoru gibi parametreler iki grup arasında benzerlik gösterirken, plasental hacim ve uterin arter Doppler sonuçlarında anlamlı farklılıklar saptanmadı.
Sonuç: Yapılan çalışmada, gruplar arasında plasental veya Doppler ölçümlerinde herhangi bir farklılık bulunmamıştır. Bugüne kadar yapılan çalışmalar genellikle gebelikte geçirilen COVID-19'un gebelikteki etkisi üzerine gerçekleştirilmiştir. Bu çalışma ise gebelik öncesi geçirilen COVID-19'un gebelikteki etkisinin belirlenmesine yardımcı olmuştur. Evaluation of First Trimester Uterine Artery Resistance, Placental Volume and pregnancy outcomes in Patients Who Had COVID-19 Before Pregnancy

References

  • 1. P, McAuliffe FM. Placental volume, vasculature and calcification in pregnancies complicated by pre-eclampsia and intra-uterine growth restriction. European Journal of Obstetrics and Gyneco- logy and Reproductive Biology. 2015 Dec 1;195:12–7. 2. Nagpal K, Mittal P, Grover SB. Role of Ultrasonographic Placental Thickness in Prediction of Fetal Outcome: A Prospec- tive Indian Study. Journal of Obstetrics and Gynecology of India. 2018 Oct 1;68(5):349–54. 3. Kliman HJ. Placental volume. Vol. 12, BMC Pregnancy and Childbirth. 2012.

Evaluation of First Trimester Uterine Artery Resistance, Placental Volume and pregnancy outcomes in Patients Who Had COVID-19 Before Pregnancy

Year 2023, Volume: 20 Issue: 3, 1894 - 1898, 01.10.2023
https://doi.org/10.38136/jgon.1345235

Abstract

Aim
There are studies showing that acquiring Coronavirus Disease 2019 (COVID-19) while pregnant might cause vascular damage, affect uterine blood circulation, and worsen pregnancy outcomes. In this study, we looked at the first-trimester placental development and pregnancy outcomes in people who conceived after getting better from COVID-19. We also looked into the durability of the COVID-19's effects on pregnancy.
Matherials and Methods
This prospective case-control study investigates placental volume and uterine artery Doppler flow differences in pregnant women with COVID-19 exposure within a year prior to pregnancy versus healthy pregnant controls.
Result
In a study involving 50 patients and 50 controls, it was discovered that demographic traits like age, birth rate, and body mass index were comparable. There were statistically insignificant slight differences in these results when different outcomes, including as oligohydramnios, preterm, preeclampsia, and intrauterine growth retardation, were studied. While birth weight revealed similarity between the two groups, placental volume and uterine artery Doppler results did not reveal any appreciable variations.
Conclusion
No distinction between the groups' placental or Doppler readings was found in the investigation that was completed. This work has helped identify the impacts of COVID-19 contracted prior to pregnancy on gestation, whereas previous study has mainly focused on the impact of COVID-19 infected during pregnancy.

References

  • 1. P, McAuliffe FM. Placental volume, vasculature and calcification in pregnancies complicated by pre-eclampsia and intra-uterine growth restriction. European Journal of Obstetrics and Gyneco- logy and Reproductive Biology. 2015 Dec 1;195:12–7. 2. Nagpal K, Mittal P, Grover SB. Role of Ultrasonographic Placental Thickness in Prediction of Fetal Outcome: A Prospec- tive Indian Study. Journal of Obstetrics and Gynecology of India. 2018 Oct 1;68(5):349–54. 3. Kliman HJ. Placental volume. Vol. 12, BMC Pregnancy and Childbirth. 2012.
There are 1 citations in total.

Details

Primary Language English
Subjects Obstetrics and Gynaecology
Journal Section Research Articles
Authors

Mehmet Özer 0000-0003-0683-0710

Pınar Tuğçe Özer 0000-0002-3571-8894

Alper İleri 0000-0002-4713-5805

Sercan Kantarcı 0000-0001-5608-060X

Halil Gürsoy Pala 0000-0003-1569-4474

Publication Date October 1, 2023
Submission Date August 17, 2023
Acceptance Date August 20, 2023
Published in Issue Year 2023 Volume: 20 Issue: 3

Cite

Vancouver Özer M, Özer PT, İleri A, Kantarcı S, Pala HG. Evaluation of First Trimester Uterine Artery Resistance, Placental Volume and pregnancy outcomes in Patients Who Had COVID-19 Before Pregnancy. JGON. 2023;20(3):1894-8.