Prenatal Dönemde Tanısı Konan İzole Koroid Pleksus Kisti Olan Hastaların 2.Trimester Biokimyasal Belirteçleri ve Gebelik Sonuçları Üzerine Etkisi
Abstract
Amaç: Prenatal ultrasonografide saptanan izole Koroid Pleksus Kistlerinde ikinci trimester yapılan biokimyasal belirteçlerine ve gebelik sonuçları üzerine etkisini araştırmak amaçlanmıştır.
Materyal Metod: Çalışma retrospektif olarak dizayn edilmiş olup 2017-2022 yılları arasında Etlik Zübeyde Hanım Kadın Hastalıkları ve Eğitim Araştırma Hastanesinde yapılmıştır. Gebeliğinde izole koroid pleksus kisti saptanan 32 gebe ve tarama ve ultrasonografisi normal olan 31 gebe kontrol grubu olarak dahil edilmiştir.
Bulgular: Çalışmaya toplam 63 gebe dahil edilmiştir. 32 gebede izole koroid pleksus kisti (KPK) vardı ve 31 gebe normaldi. Gruplar arasında Estriol (E3) MoM KPK olan grupta diğer gruba göre düşüktü ve istatiksel olarak anlamlıydı ama yinede kabul edilen sınır değerler arasındaydı diğer biokimyasal parametreler açısından anlamlı istatiksel fark bulunmadı. Doğum sonuçları arasında fark bulunamadı. Hiçbir yenidoğanda anomali saptanmadı.
Sonuç: 2. Trimestar biokimyasal belirteçleri normal olan ve izole KPK sı olan fetuslarda anomali riski çok düşüktür
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References
- 1. Vintzileos AM, Campbell WA, Rodis JF, Guzman ER, Smulian JC, Knuppel R. The use of second trimester genetic sonogram in guiding clinical management of patients at risk for fetal trisomy 21. Obstet Gynecol 1996;87:948-52. 2. Nicolaides, K.H., Rodeck, C.H., Gosden, C.M. (1986). Rapid karyotyping in non-lethal fetal malformations, Lancet, 283-287 3. Gabrielli S, Reece EA, Pilu G, et al. The clinical sig- nificance of prenatally diagnosed choroid plexus cysts. Am J Obstet Gynecol 1989;160:1207-10. 4. Benacerraf BR, Harlow B, Frigoletto FD Jr. Are choro- id plexus cysts an indication for second-trimester amniocente- sis? Am J Obstet Gynecol 1990;162:1001-6. 5. Bestwick JP, Huttly WJ, Wald NJ. Detection of trisomy 18 and trisomy 13 using first and second trimester Down’s sy- ndrome screening markers. J Med Screen. 2013 Jun;20(2):57- 65. doi: 10.1177/0969141313484904. Epub 2013 May 28. Erra- tum in: J Med Screen. 2015 Mar;22(1):52-4. PMID: 23761419.
The Effect on 2nd Trimester Biochemical Markers and Pregnancy Outcomes of Patients with Isolated Choroid Plexus Cyst Diagnosed in the Prenatal Period
Abstract
Aim: It was aimed to investigate the effects of second trimester biochemical markers and pregnancy outcomes in isolated Choroid Plexus Cysts detected in prenatal ultrasonography.
Material and Method: The study was designed retrospectively and was conducted in Etlik Zübeyde Hanım Gynecology and Training and Research Hospital between 2017-2022. 32 pregnant women with isolated choroid plexus cyst and 31 pregnant women with normal screening and ultrasonography were included as the control group.
Results: A total of 63 pregnant women were included in the study. 32 pregnant women had isolated choroid plexus cyst (CPC) and 31 pregnant women were normal. Estriol (E3) MoM was lower in the group with CPC and statistically significant between the groups, but it was still between the accepted cut-off values, and no statistically significant difference was found in terms of other biochemical parameters. No difference was found between birth outcomes. No anomaly was detected in any newborn.
Conclusion: Anomaly risk is very low in fetuses with normal 2nd trimester biochemical markers and isolated CPC.
References
- 1. Vintzileos AM, Campbell WA, Rodis JF, Guzman ER, Smulian JC, Knuppel R. The use of second trimester genetic sonogram in guiding clinical management of patients at risk for fetal trisomy 21. Obstet Gynecol 1996;87:948-52. 2. Nicolaides, K.H., Rodeck, C.H., Gosden, C.M. (1986). Rapid karyotyping in non-lethal fetal malformations, Lancet, 283-287 3. Gabrielli S, Reece EA, Pilu G, et al. The clinical sig- nificance of prenatally diagnosed choroid plexus cysts. Am J Obstet Gynecol 1989;160:1207-10. 4. Benacerraf BR, Harlow B, Frigoletto FD Jr. Are choro- id plexus cysts an indication for second-trimester amniocente- sis? Am J Obstet Gynecol 1990;162:1001-6. 5. Bestwick JP, Huttly WJ, Wald NJ. Detection of trisomy 18 and trisomy 13 using first and second trimester Down’s sy- ndrome screening markers. J Med Screen. 2013 Jun;20(2):57- 65. doi: 10.1177/0969141313484904. Epub 2013 May 28. Erra- tum in: J Med Screen. 2015 Mar;22(1):52-4. PMID: 23761419.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Obstetrics and Gynaecology, Reproductive Medicine (Other) |
| Journal Section | Research Articles |
| Authors | |
| Publication Date | December 31, 2023 |
| Submission Date | June 3, 2023 |
| Acceptance Date | August 3, 2023 |
| Published in Issue | Year 2023 Volume: 20 Issue: 4 |
