Abstract
Thanks
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References
- Drouin G, JR Godin, B Pagé, The genetics of vitamin C loss in vertebrates. Curr Genomics 2011; 12: 371-8.
- Carr AC, Maggini S. Vitamin C and immune function. Nutrients 2017; 9: 1211.
- Maggini S, Wintergerst ES, Beveridge S, Hornig DH. Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. Br J Nutr 2007; 98: 29-35.
- German Nutrition Society (DGE). New reference values for vitamin C intake. Ann Nutr Metab 2015; 67: 13-20.
- Holford P, Carr AC, Jovic TH, et al. Vitamin C-an adjunctive therapy for respiratory infection, sepsis and COVID-19. Nutrients 2020; 12: 3760.
- Naserghandi A, Allameh SF, Saffarpour R. All about COVID-19 in brief. New Microbes New Infect 2020; 35: 100678.
- Hemilä H. Vitamin C and infections. Nutrients 2017; 9: 339.
- Hume R, Weyers E. Changes in leucocyte ascorbic acid during the common cold. Scott Med J 1973; 18: 3-7.
- Carr AC, Rowe S. The emerging role of vitamin C in the prevention and treatment of COVID-19. Nutrients 2020; 12: 3286.
- Johnston CS, Cox SK. Plasma-saturating intakes of vitamin C confer maximal antioxidant protection to plasma. J Am Coll Nutr 2001; 20: 623-7.
- Ministry of Health, Press Release '' Fahrettin Koca announced the number for the first time: 29,865 healthcare workers are infected....”. Medimagazin 2020; Available from: https://www.medimagazin.com.tr/guncel/genel/tr-fahrettin-koca-ilk-kez-sayi-verdi-29-bin865-saglik-calisani-enfekte-11-681-91089.html.
- Stoecklin SB, Rolland P, Silue Y, et al., First cases of coronavirus disease 2019 (COVID-19) in France: surveillance, investigations and control measures, January 2020. Euro Surveill 2020; 25: 2000094
- Lu R, Zhao X, Li J, et al., Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020; 395: 565-74.
- Erbay A. Long COVID: a new definition. Bozok Tıp Derg 2020; 10: 111-4.
- Mousavi S, Bereswil S, Heimesaat MM. Immunomodulatory and antimicrobial effects of vitamin C. Eur J Microbiol Immunol (Bp) 2019; 9: 73-9.
- Liu F, Zhu Y, Zhang J, Li Y, Peng Z. Intravenous high-dose vitamin C for the treatment of severe COVID-19: study protocol for a multicentre randomised controlled trial. BMJ Open 2020; 10: 039519.
- Hemilä H, Louhiala P. Vitamin C for preventing and treating pneumonia. Cochrane Database Syst Rev 2013; 8: 005532.
- Feyaerts AF, Luyten W. Vitamin C as prophylaxis and adjunctive medical treatment for COVID-19? Nutrition 2020; 79: 110948.
Abstract
Aim: In vitamin C deficiency, the immune system deteriorates and the body becomes more susceptible to infections. Since vitamin C levels will decrease significantly in infectious conditions due to increased metabolic requirements, the daily need for vitamin C increases. In our study, it was aimed to investigate the effects of 500 mg and more vitamin C intake on COVID-19 infection during the pandemic process.
Material and Method: A group consisting of 100 participants who received vitamin C supplements at a daily dose of at least 500 mg daily for a minimum of 1-3 months in their diet and a control group of 100 people who did not receive vitamin supplements were included in the study. While determining the amount of Vitamin C intake of the participants; The amount of Vitamin C in oral food supplements or foods containing vitamin C in their diets (orange, tangerine, grapefruit, kiwi, pineapple, strawberry, lemon, red and green peppers, tomatoes, arugula, parsley, greens such as lettuce, fresh rosehip, broccoli, cabbage, spinach) The vitamin level was calculated according to the amount of vegetables (such as vegetables). None of the participants had side effects suggestive of vitamin C toxicity. Besides the height, weight, gender, age, known illness and other demographic data of all participants; COVID-19 disease status, contact with COVID-19 patients, and whether or not they had a COVID infection after contact were examined. In addition, data on the presence of symptoms, severity and duration of the disease were noted in patients with COVID-19 infection, and both groups were compared statistically in terms of results.
Results: In the group receiving less than 500 mg daily; COVID-19 infection symptoms, respiratory distress, disease severity were found to be higher, and the symptoms were found to be more aggressive. While total contact and high-risk contact at all levels was higher in the group that received more than 500 mg of vitamin C daily, the rate of being COVID was lower compared to the other groups.
Conclusion: One of the most effective precautions to be taken to increase body resistance against COVID-19 is adequate vitamin C intake. In the study, it has been shown that adequate vitamin C taken with both food and nutritional supplements reduce the risk of getting COVID-19, reduce the risk of severe respiratory distress on COVID-19, as well as reduce both symptoms and symptom duration.
References
- Drouin G, JR Godin, B Pagé, The genetics of vitamin C loss in vertebrates. Curr Genomics 2011; 12: 371-8.
- Carr AC, Maggini S. Vitamin C and immune function. Nutrients 2017; 9: 1211.
- Maggini S, Wintergerst ES, Beveridge S, Hornig DH. Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. Br J Nutr 2007; 98: 29-35.
- German Nutrition Society (DGE). New reference values for vitamin C intake. Ann Nutr Metab 2015; 67: 13-20.
- Holford P, Carr AC, Jovic TH, et al. Vitamin C-an adjunctive therapy for respiratory infection, sepsis and COVID-19. Nutrients 2020; 12: 3760.
- Naserghandi A, Allameh SF, Saffarpour R. All about COVID-19 in brief. New Microbes New Infect 2020; 35: 100678.
- Hemilä H. Vitamin C and infections. Nutrients 2017; 9: 339.
- Hume R, Weyers E. Changes in leucocyte ascorbic acid during the common cold. Scott Med J 1973; 18: 3-7.
- Carr AC, Rowe S. The emerging role of vitamin C in the prevention and treatment of COVID-19. Nutrients 2020; 12: 3286.
- Johnston CS, Cox SK. Plasma-saturating intakes of vitamin C confer maximal antioxidant protection to plasma. J Am Coll Nutr 2001; 20: 623-7.
- Ministry of Health, Press Release '' Fahrettin Koca announced the number for the first time: 29,865 healthcare workers are infected....”. Medimagazin 2020; Available from: https://www.medimagazin.com.tr/guncel/genel/tr-fahrettin-koca-ilk-kez-sayi-verdi-29-bin865-saglik-calisani-enfekte-11-681-91089.html.
- Stoecklin SB, Rolland P, Silue Y, et al., First cases of coronavirus disease 2019 (COVID-19) in France: surveillance, investigations and control measures, January 2020. Euro Surveill 2020; 25: 2000094
- Lu R, Zhao X, Li J, et al., Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020; 395: 565-74.
- Erbay A. Long COVID: a new definition. Bozok Tıp Derg 2020; 10: 111-4.
- Mousavi S, Bereswil S, Heimesaat MM. Immunomodulatory and antimicrobial effects of vitamin C. Eur J Microbiol Immunol (Bp) 2019; 9: 73-9.
- Liu F, Zhu Y, Zhang J, Li Y, Peng Z. Intravenous high-dose vitamin C for the treatment of severe COVID-19: study protocol for a multicentre randomised controlled trial. BMJ Open 2020; 10: 039519.
- Hemilä H, Louhiala P. Vitamin C for preventing and treating pneumonia. Cochrane Database Syst Rev 2013; 8: 005532.
- Feyaerts AF, Luyten W. Vitamin C as prophylaxis and adjunctive medical treatment for COVID-19? Nutrition 2020; 79: 110948.
Details
| Primary Language | English |
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| Subjects | Health Care Administration |
| Journal Section | Original Article |
| Authors | |
| Publication Date | January 17, 2022 |
| Published in Issue | Year 2022 Volume: 5 Issue: 1 |
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