Research Article
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Year 2023, Volume: 5 Issue: 1, 1 - 5, 30.06.2023

Abstract

Supporting Institution

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Project Number

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References

  • Bakris GL. (1995). Pathogenesis of hypertension in diabetes. Diabetes Reviews, 3:460-76.
  • Beşirbellioğlu BA. (2007). SARS kuşkulu ve damlacık çekirdeği ile bulaşan infeksiyonlarda DAS yönetimi. 5. Ulusal Sterilizasyon Dezenfeksiyon Kongresi. 4-8 Nisan 2007. 502-504. 8.
  • Brufsky A. (2020). Hyperglycemia, hydroxychloroquine, and the COVID- 19 pandemic. J. Med. Virol, 92(7):770–775.
  • Cascella M, Rajnik M, Aleem A, Dulebohn SC, Di Napoli R. (2023). Features, Evaluation, and Treatment of Coronavirus (COVID-19). 2023 Jan 9. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 32150360.
  • Çelik D, Köse Ş. (2020). Erişkinlerde COVID-19: Klinik bulgular. Tepecik Eğit. ve Araşt. Hast. Dergisi, 30 (Ek sayı):43-48.
  • De Fronzo RA, Goldberg M, Agus ZS. (1976). The effects of glucose and insulin on renal electrolyte transport. J Clin Invest., 58(1):83-90. https://doi.org/10.1172/JCI108463
  • Despres JP, Lamarche B, Mauriege P, et al. (1996). Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med, 334(15):952-7. https://doi.org/10.1056/ NEJM199604113341504
  • Fu L, Wang B, Yuan T. (2020). Clinical characteristics of coronavirus disease 2019 (COVID 19) In China: A systematic review and meta-analysis. J Infect, 80(6):656-665. doi:10.1016/j.jinf.2020.03.041
  • Guo W, Li M, Dong Y, et al. (2020). Diabetes is a risk factor for theprogression and prognosis of COVID-19. Diabetes Metab Res Rev, 31;36(7):e3319. doi: 10.1002/dmrr.3319.
  • Gupta R, Ghosh A, Singh AK, Misra A. (2020). Clinical considerations for diabetes in times of COVID-19 epidemic. Diabetes Metab Syndr, 14(3):211-212. doi: 10.1016/j.dsx.2020.03.002.
  • Hill MA, Mantzoros C, Sowers JR. (2020). Commentary: COVID-19 in patients with diabetes. Metabolism, 107:154217. doi: 10.1016/j.metabol.2020.154217.
  • Kutlutürk F. (2020). COVID-19 Pandemisi ve Diabetes Mellitus. Türk Diyab Obez, 2:130-137.
  • Sheu WH, Jeng CY, Young MS, et al. (2000). Coronary artery disease risk predicted by insulin resistance, plasma lipids, and hypertension in people without diabetes. Am J Med Sci, 319(2):84-8. https://doi.org/10.1097/00000441- 200002000-00003
  • Reaven GM. (1988). Role of insulin resistance in human disease. Diabetes, 37:1595-607. https://doi.org/10.2337/diab.37.12.1595.
  • Scott M, Grundy MD, James I, et al.(2005). Diagnosis and management of the metabolic syndrome. Circulation, 112(17):2735-52.
  • Soliman AT, Al-Amri M, Alleethy K, Alaaraj N, Hamed N, De Sanctis V. (2020). Newly-onset type 1 diabetes mellitus precipitated by COVID- 19 in an 8-month-old infant. Acta Biomed, 91(3):ahead of print. doi: 10.23750/abm.v91i3.10074.
  • Yazar H, Kayacan Y, Özdin M. (2021). Investigation of C-reactive Protein and D-dimer Findings in Patients with COVID-19. Bezmialem Science, 9(Supplement 1):4-8.
  • Zhu L, She ZG, Cheng X, Qin JJ, Zhang XJ, Cai J, et al. (2020). Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes. Cell Metab, 31(6):1068-1077.

Comparison of HOMA-IR Values in Covid-19 Negative and Positive Patients

Year 2023, Volume: 5 Issue: 1, 1 - 5, 30.06.2023

Abstract

Objective:
This study compared the HOMA-IR values of COVID-19 patients with COVID-19-negative patients.
Method:
A total of 2116 COVID-19 + patients, 1186 men and 850 women, and 1127 COVID-19 - patients, 313 men and 814 women, were included in the study. The study was conducted on patients with definite COVID-19 + and - between June 1, 2020 and July 31, 2020. The patients' data were obtained retrospectively from the hospital information management system. The diagnosis of COVID-19 in the included patients was made by a real-time polymerase chain reaction and computed tomography lung scanning. The relationship between the HOMA IR values of COVID-19 + and - patients was compared.
Results:
The HOMA IR value of patients who were positive without gender discrimination was found to be significantly higher in patients with COVİD-19 + patients. No significant gender differences were detected in HOMA IR values in COVİD-19 + patients. The HOMA IR values of men were found to be significantly higher in patients with COVID-19 – patients in differences according to gender. A positive correlation was found between age and HOMA IR in COVID-19 patients. No significant relationship was found between age and HOMA IR in COVİD-19 + patients.
Conclusion:
It was determined that there was no significant difference in HOMA-IR values in COVID-19 + patients according to gender, and the HOMA-IR values of patients with COVID-19 + were found to be significantly higher without gender discrimination.

Project Number

-

References

  • Bakris GL. (1995). Pathogenesis of hypertension in diabetes. Diabetes Reviews, 3:460-76.
  • Beşirbellioğlu BA. (2007). SARS kuşkulu ve damlacık çekirdeği ile bulaşan infeksiyonlarda DAS yönetimi. 5. Ulusal Sterilizasyon Dezenfeksiyon Kongresi. 4-8 Nisan 2007. 502-504. 8.
  • Brufsky A. (2020). Hyperglycemia, hydroxychloroquine, and the COVID- 19 pandemic. J. Med. Virol, 92(7):770–775.
  • Cascella M, Rajnik M, Aleem A, Dulebohn SC, Di Napoli R. (2023). Features, Evaluation, and Treatment of Coronavirus (COVID-19). 2023 Jan 9. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 32150360.
  • Çelik D, Köse Ş. (2020). Erişkinlerde COVID-19: Klinik bulgular. Tepecik Eğit. ve Araşt. Hast. Dergisi, 30 (Ek sayı):43-48.
  • De Fronzo RA, Goldberg M, Agus ZS. (1976). The effects of glucose and insulin on renal electrolyte transport. J Clin Invest., 58(1):83-90. https://doi.org/10.1172/JCI108463
  • Despres JP, Lamarche B, Mauriege P, et al. (1996). Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med, 334(15):952-7. https://doi.org/10.1056/ NEJM199604113341504
  • Fu L, Wang B, Yuan T. (2020). Clinical characteristics of coronavirus disease 2019 (COVID 19) In China: A systematic review and meta-analysis. J Infect, 80(6):656-665. doi:10.1016/j.jinf.2020.03.041
  • Guo W, Li M, Dong Y, et al. (2020). Diabetes is a risk factor for theprogression and prognosis of COVID-19. Diabetes Metab Res Rev, 31;36(7):e3319. doi: 10.1002/dmrr.3319.
  • Gupta R, Ghosh A, Singh AK, Misra A. (2020). Clinical considerations for diabetes in times of COVID-19 epidemic. Diabetes Metab Syndr, 14(3):211-212. doi: 10.1016/j.dsx.2020.03.002.
  • Hill MA, Mantzoros C, Sowers JR. (2020). Commentary: COVID-19 in patients with diabetes. Metabolism, 107:154217. doi: 10.1016/j.metabol.2020.154217.
  • Kutlutürk F. (2020). COVID-19 Pandemisi ve Diabetes Mellitus. Türk Diyab Obez, 2:130-137.
  • Sheu WH, Jeng CY, Young MS, et al. (2000). Coronary artery disease risk predicted by insulin resistance, plasma lipids, and hypertension in people without diabetes. Am J Med Sci, 319(2):84-8. https://doi.org/10.1097/00000441- 200002000-00003
  • Reaven GM. (1988). Role of insulin resistance in human disease. Diabetes, 37:1595-607. https://doi.org/10.2337/diab.37.12.1595.
  • Scott M, Grundy MD, James I, et al.(2005). Diagnosis and management of the metabolic syndrome. Circulation, 112(17):2735-52.
  • Soliman AT, Al-Amri M, Alleethy K, Alaaraj N, Hamed N, De Sanctis V. (2020). Newly-onset type 1 diabetes mellitus precipitated by COVID- 19 in an 8-month-old infant. Acta Biomed, 91(3):ahead of print. doi: 10.23750/abm.v91i3.10074.
  • Yazar H, Kayacan Y, Özdin M. (2021). Investigation of C-reactive Protein and D-dimer Findings in Patients with COVID-19. Bezmialem Science, 9(Supplement 1):4-8.
  • Zhu L, She ZG, Cheng X, Qin JJ, Zhang XJ, Cai J, et al. (2020). Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes. Cell Metab, 31(6):1068-1077.
There are 18 citations in total.

Details

Primary Language English
Subjects Public Health, Environmental Health
Journal Section Research Articles
Authors

Mehmet Özdin 0000-0003-3077-7171

Project Number -
Early Pub Date June 29, 2023
Publication Date June 30, 2023
Submission Date May 24, 2023
Published in Issue Year 2023 Volume: 5 Issue: 1

Cite

APA Özdin, M. (2023). Comparison of HOMA-IR Values in Covid-19 Negative and Positive Patients. Doğal Yaşam Tıbbı Dergisi, 5(1), 1-5.
AMA Özdin M. Comparison of HOMA-IR Values in Covid-19 Negative and Positive Patients. JNLM. June 2023;5(1):1-5.
Chicago Özdin, Mehmet. “Comparison of HOMA-IR Values in Covid-19 Negative and Positive Patients”. Doğal Yaşam Tıbbı Dergisi 5, no. 1 (June 2023): 1-5.
EndNote Özdin M (June 1, 2023) Comparison of HOMA-IR Values in Covid-19 Negative and Positive Patients. Doğal Yaşam Tıbbı Dergisi 5 1 1–5.
IEEE M. Özdin, “Comparison of HOMA-IR Values in Covid-19 Negative and Positive Patients”, JNLM, vol. 5, no. 1, pp. 1–5, 2023.
ISNAD Özdin, Mehmet. “Comparison of HOMA-IR Values in Covid-19 Negative and Positive Patients”. Doğal Yaşam Tıbbı Dergisi 5/1 (June 2023), 1-5.
JAMA Özdin M. Comparison of HOMA-IR Values in Covid-19 Negative and Positive Patients. JNLM. 2023;5:1–5.
MLA Özdin, Mehmet. “Comparison of HOMA-IR Values in Covid-19 Negative and Positive Patients”. Doğal Yaşam Tıbbı Dergisi, vol. 5, no. 1, 2023, pp. 1-5.
Vancouver Özdin M. Comparison of HOMA-IR Values in Covid-19 Negative and Positive Patients. JNLM. 2023;5(1):1-5.