Abstract
References
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- 6. Niki K, Okamoto Y, Matano Y, et al. Validation of a Short-Term, Objective, Prognostic Predictive Method for Terminal Cancer Patients in a Palliative Care Unit Using a Combination of Six Laboratory Test Items. J Palliat Med. 2019;22(6):685-690.
- 7. Forrest LM, McMillan DC, McArdle CS, et al. Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer. Br J Cancer. 2003;89(6):1028-1030.
- 8. Morita T, Tsunoda J, Inoue S, et al. The Palliative Prognostic Index: a scoring system for survival prediction of terminally ill cancer patients. Support Care Cancer. 1999;7(3):128-133.
- 9. Lyons O, Whelan B, Bennett K, et al. Serum albumin as an outcome predictor in hospital emergency medical admissions. Eur J Intern Med. 2010;21(1):17-20.
- 10. Tal S, Guller V, Shavit Y, et al. Mortality predictors in hospitalized elderly patients. QJM. 2011;104(11):933-938.
- 11. Haller C. Hypoalbuminemia in renal failure: pathogenesis and therapeutic considerations. Kidney Blood Press Res. 2005;28(5-6):307-310.
- 12. Aung A, Alqudihy S, Rybicki L, et al. Does serum albumin and creatinine predict survival of inpatient palliative care patients?. Am J Hosp Palliat Care. 2014;31(8):862-866.
- 13. Elsayem A, Mori M, Parsons HA, et al. Predictors of inpatient mortality in an acute palliative care unit at a comprehensive cancer center. Support Care Cancer. 2010;18(1):67-76.
- 14. Kripp M, Willer A, Schmidt C, et al. Patients with malignant hematological disorders treated on a palliative care unit: prognostic impact of clinical factors. Ann Hematol. 2014;93(2):317-325.
- 15. Yürüyen M, Özbaş Tevetoğlu I, Tekmen Y, et al. Prognostic Factors and Clinical Features in Palliative Care Patients. Konuralp Tıp Dergisi. 2018;10(1):74-80.
Comparison of the Laboratory Values at Admission to Palliative Care Unit: Geriatric vs Non-Geriatric Patients
Abstract
Aim: The aim of the present study is to compare the laboratory findings during the palliative care unit (PCU) admission of non-geriatric and geriatric patients and to evaluate the effects of these findings.
Methods: In the present study medical records of the patients hospitalized in PCU between 18.10.2018-18.10.2020 were reviewed. The patients were evaluated in 2 groups: Group I; 65 years and older and Group II; 18-64 years old. Demographic data and laboratory values of the patients (C-reactive protein, glucose, urea, creatinine, sodium, potassium, albumin, mean platelet volume and platelet, lymphocyte, neutrophil counts) were recorded. From these values, CRP/albumin, neutrophil/lymphocyte ratio, and platelet/lymphocyte ratio were calculated. Length of stay and mortality were also recorded.
Results: A total of 454 patients (Group I: 249 and Group II: 205) were included in the study. Blood glucose, urea, creatinine and sodium values were found to be statistically higher in Group I (p=0.027, p<0.001, p<0.001 and p=0.032, respectively). Albumin values were 2.70 g/dL (2.30–3.00 g/dL) in Group I and statistically lower than Group II (p<0.001). Albumin < 2.5 g/dL [odds ratio (OR) 2.75, 95% confidence interval (CI): 1.52–4.96, p < 0.001] was determined as an independent risk factor for mortality in Group I. While the sensitivity was determined as 79% for the albumin cut-off value of 2.5 g/dL, the specificity was determined as 66%.
Conclusions: Among the laboratory values at the time of admission of geriatric patients admitted to the PCU, only albumin has a prognostic value in poor sensitivity and specificity.
Keywords
References
- 1. Dalgaard KM, Bergenholtz H, Nielsen ME, et al. Early integration of palliative care in hospitals: A systematic review on methods, barriers, and outcome. Palliat Support Care. 2014;12(6):495-513.
- 2. Bureau of the Census. Projections of the population by age and sex for the United States: 2010 to 2050. 2008. Available at: http://www.census.gov/prod/2010pubs/ p25-1138.pdf. Accessed February 20, 2015.
- 3. Centers for Disease Control and Prevention (CDC). The state of aging and health in America—2013. 2013.
- 4. Higginson IJ, Davies E. Better Palliative Care for Older People. World Health Organization, Copenhagen, Denmark, 2004.
- 5. Corkum M, Viola R, Veenema C, et al. Prognosticating in palliative care: a survey of Canadian palliative care physicians. J Palliat Care. 2011;27(2):89-97.
- 6. Niki K, Okamoto Y, Matano Y, et al. Validation of a Short-Term, Objective, Prognostic Predictive Method for Terminal Cancer Patients in a Palliative Care Unit Using a Combination of Six Laboratory Test Items. J Palliat Med. 2019;22(6):685-690.
- 7. Forrest LM, McMillan DC, McArdle CS, et al. Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer. Br J Cancer. 2003;89(6):1028-1030.
- 8. Morita T, Tsunoda J, Inoue S, et al. The Palliative Prognostic Index: a scoring system for survival prediction of terminally ill cancer patients. Support Care Cancer. 1999;7(3):128-133.
- 9. Lyons O, Whelan B, Bennett K, et al. Serum albumin as an outcome predictor in hospital emergency medical admissions. Eur J Intern Med. 2010;21(1):17-20.
- 10. Tal S, Guller V, Shavit Y, et al. Mortality predictors in hospitalized elderly patients. QJM. 2011;104(11):933-938.
- 11. Haller C. Hypoalbuminemia in renal failure: pathogenesis and therapeutic considerations. Kidney Blood Press Res. 2005;28(5-6):307-310.
- 12. Aung A, Alqudihy S, Rybicki L, et al. Does serum albumin and creatinine predict survival of inpatient palliative care patients?. Am J Hosp Palliat Care. 2014;31(8):862-866.
- 13. Elsayem A, Mori M, Parsons HA, et al. Predictors of inpatient mortality in an acute palliative care unit at a comprehensive cancer center. Support Care Cancer. 2010;18(1):67-76.
- 14. Kripp M, Willer A, Schmidt C, et al. Patients with malignant hematological disorders treated on a palliative care unit: prognostic impact of clinical factors. Ann Hematol. 2014;93(2):317-325.
- 15. Yürüyen M, Özbaş Tevetoğlu I, Tekmen Y, et al. Prognostic Factors and Clinical Features in Palliative Care Patients. Konuralp Tıp Dergisi. 2018;10(1):74-80.
Details
| Primary Language | English |
|---|---|
| Subjects | Geriatrics and Gerontology |
| Journal Section | Articles |
| Authors | |
| Publication Date | December 31, 2023 |
| Acceptance Date | August 22, 2023 |
| Published in Issue | Year 2023 Volume: 6 Issue: 3 |
