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Evaluation of ultrasonic intravascular thrombectomy system on a rabbit model in the treatment of deep vein thrombosis

Year 2021, Volume: 5 Issue: 9, 921 - 923, 01.09.2021

Ferit Kasimzade Fatih Ada Özhan Karataş

https://doi.org/10.28982/josam.974368

Abstract

Background/Aim: Advanced treatment options are needed in deep venous thrombosis (DVT), which is a special subgroup of venous disease. We examined this subgroup on an animal model and aimed to evaluate the effects of the ultrasonic intravascular thrombectomy system on vascular endothelial damage.
Methods: A total of 24 rabbits in 3 groups were used in the study. DVT was created in the common iliac vein by the administration of intravascular fibrin. One hour passed for DVT formation. The ultrasonic intravascular thrombectomy system and the mechanical thrombectomy system were used separately in the DVT groups. After one hour, samples obtained from the groups were examined histologically.
Results: Significantly less endothelial damage was detected in the ultrasonic intravascular thrombectomy system group compared to the mechanical thrombectomy group (P<0.05).
Conclusions: Ultrasonic intravascular thrombectomy method minimizes the thrombus load and causes minimal endothelial damage. These findings show that the ultrasonic intravascular thrombectomy method can be used successfully in DVT treatment.

Keywords

Deep vein thrombosis Ultrasonic intravascular thrombectomy system Animal model Endothelial injury

References

  • 1. Cay N, Unal O, Kartal MG, Ozdemir M, Tola M. Increased level of red blood cell distribution width is associated with deep venous thrombosis. Blood Coagulation & Fibrinolysis. 2013;24(7):727-31.
  • 2. Ada F, Polat V. Evaluation of platelet indices in acute, subacute and, chronic phases of deep venous thrombosis. Cumhuriyet Medical Journal. 2019;41(3):544-50.
  • 3. Han JS, Park TS, Cho SY, Joh JH, Ahn HJ. Increased mean platelet volume and mean platelet volume/platelet count ratio in Korean patients with deep vein thrombosis. Platelets. 2013;24(8):590-3.
  • 4. Willans DJ, Mill SC, Ranney EK. Common thrombotic disorders defined by CBC platelet parameters. Clinical and Applied Thrombosis/Hemostasis. 1995;1(3):188-201.
  • 5. Itoh K, Ieko M, Hiraguchi E, Kitayama H, Tsukamoto E. In vivo kinetics of 99m Tc labeled recombinant tissue plasminogen activator in rabbits. Annals of Nuclear Medicine. 1994;8(3):193-9.
  • 6. Wiwanitkit V. Plateletcrit, mean platelet volume, platelet distribution width: its expected values and correlation with parallel red blood cell parameters. Clinical and Applied Thrombosis/Hemostasis. 2004;10(2):175-8.
  • 7. Lichtenberg M, de Graaf R, Jalaie H. Acute and chronic venous outflow obstructions–a global burden. Vasa. 2021;50(1):1.
  • 8. Kasirajan K, Gray B, Ouriel K. Percutaneous AngioJet thrombectomy in the management of extensive deep venous thrombosis. Journal of Vascular and Interventional Radiology. 2001;12(2):179-85.
  • 9. Delomez M, Beregi JP, Willoteaux S, Bauchart JJ, d’Othée BJ, Asseman P, et al. Mechanical thrombectomy in patients with deep venous thrombosis. CardioVascular and Interventional Radiology. 2001;24(1):42-8.
  • 10. Biuckians A, Meier III GH. Treatment of symptomatic lower extremity acute deep venous thrombosis: role of mechanical thrombectomy. Vascular. 2007;15(5):297-303.
  • 11. Augustinos P, Ouriel K. Invasive approaches to treatment of venous thromboembolism. Circulation. 2004;110(9_suppl_1), I-27.
  • 12. Chandra V, Dwyer D, Quadri R, Sharma A, Khaja M, Matson J. Initial Experience with Inari Thrombectomy Systems for Single-Session Suction Thrombectomy of Iliocaval Thrombus. Journal of Vascular Surgery: Venous and Lymphatic Disorders. 2021;9(2):540-1.
  • 13. Shi HJ, Huang YH, Shen T, Xu Q. Percutaneous mechanical thrombectomy combined with catheter-directed thrombolysis in the treatment of symptomatic lower extremity deep venous thrombosis. European Journal of Radiology. 2009;71(2):350-5.
  • 14. Murphy KD. Mechanical thrombectomy for DVT. Techniques in Vascular and Interventional Radiology. 2004;7(2):79-85.
  • 15. Vedantham S, Vesely TM, Parti N, Darcy M, Hovsepian DM, Picus D. Lower extremity venous thrombolysis with adjunctive mechanical thrombectomy. Journal of Vascular and Interventional Radiology. 2002;13(10):1001-8.
  • 16. Lin PH, Zhou W, Dardik A, Mussa F, Kougias P, Hedayati N, et al. Catheter-direct thrombolysis versus pharmacomechanical thrombectomy for treatment of symptomatic lower extremity deep venous thrombosis. The American Journal of Surgery. 2006;192(6):782-8.
  • 17. Blackwood S, Dietzek AM. Pharmacomechanical thrombectomy: 2015 update. Expert Review of Cardiovascular Therapy. 2016;14(4):463-75.
  • 18. Kutsukata N, Mashiko K, Matsumoto H, Hara Y, Sakamoto Y, Yokota H, et al. Surgical venous thrombectomy for Japanese patients with acute deep vein thrombosis: a review of 5 years' experience. Journal of Nippon Medical School. 2010;77(3):155-9.
  • 19. Kasirajan K, Milner R, Chaikof EL. Combination therapies for deep venous thrombosis. Seminars in Vascular Surgery. 2006;19(2):116-21.
  • 20. Karthikesalingam A, Young EL, Hinchliffe RJ, Loftus IM, Thompson MM, Holt PJE. A systematic review of percutaneous mechanical thrombectomy in the treatment of deep venous thrombosis. European Journal of Vascular and Endovascular Surgery. 2011;41(4):554-65.
  • 21. Arko FR, Davis CM, Murphy EH, Smith ST, Timaran CH, Modrall JG, et al. Aggressive percutaneous mechanical thrombectomy of deep venous thrombosis: early clinical results. Archives of Surgery. 2007;142(6):513-9.

Year 2021, Volume: 5 Issue: 9, 921 - 923, 01.09.2021

Ferit Kasimzade Fatih Ada Özhan Karataş

https://doi.org/10.28982/josam.974368

Abstract

References

  • 1. Cay N, Unal O, Kartal MG, Ozdemir M, Tola M. Increased level of red blood cell distribution width is associated with deep venous thrombosis. Blood Coagulation & Fibrinolysis. 2013;24(7):727-31.
  • 2. Ada F, Polat V. Evaluation of platelet indices in acute, subacute and, chronic phases of deep venous thrombosis. Cumhuriyet Medical Journal. 2019;41(3):544-50.
  • 3. Han JS, Park TS, Cho SY, Joh JH, Ahn HJ. Increased mean platelet volume and mean platelet volume/platelet count ratio in Korean patients with deep vein thrombosis. Platelets. 2013;24(8):590-3.
  • 4. Willans DJ, Mill SC, Ranney EK. Common thrombotic disorders defined by CBC platelet parameters. Clinical and Applied Thrombosis/Hemostasis. 1995;1(3):188-201.
  • 5. Itoh K, Ieko M, Hiraguchi E, Kitayama H, Tsukamoto E. In vivo kinetics of 99m Tc labeled recombinant tissue plasminogen activator in rabbits. Annals of Nuclear Medicine. 1994;8(3):193-9.
  • 6. Wiwanitkit V. Plateletcrit, mean platelet volume, platelet distribution width: its expected values and correlation with parallel red blood cell parameters. Clinical and Applied Thrombosis/Hemostasis. 2004;10(2):175-8.
  • 7. Lichtenberg M, de Graaf R, Jalaie H. Acute and chronic venous outflow obstructions–a global burden. Vasa. 2021;50(1):1.
  • 8. Kasirajan K, Gray B, Ouriel K. Percutaneous AngioJet thrombectomy in the management of extensive deep venous thrombosis. Journal of Vascular and Interventional Radiology. 2001;12(2):179-85.
  • 9. Delomez M, Beregi JP, Willoteaux S, Bauchart JJ, d’Othée BJ, Asseman P, et al. Mechanical thrombectomy in patients with deep venous thrombosis. CardioVascular and Interventional Radiology. 2001;24(1):42-8.
  • 10. Biuckians A, Meier III GH. Treatment of symptomatic lower extremity acute deep venous thrombosis: role of mechanical thrombectomy. Vascular. 2007;15(5):297-303.
  • 11. Augustinos P, Ouriel K. Invasive approaches to treatment of venous thromboembolism. Circulation. 2004;110(9_suppl_1), I-27.
  • 12. Chandra V, Dwyer D, Quadri R, Sharma A, Khaja M, Matson J. Initial Experience with Inari Thrombectomy Systems for Single-Session Suction Thrombectomy of Iliocaval Thrombus. Journal of Vascular Surgery: Venous and Lymphatic Disorders. 2021;9(2):540-1.
  • 13. Shi HJ, Huang YH, Shen T, Xu Q. Percutaneous mechanical thrombectomy combined with catheter-directed thrombolysis in the treatment of symptomatic lower extremity deep venous thrombosis. European Journal of Radiology. 2009;71(2):350-5.
  • 14. Murphy KD. Mechanical thrombectomy for DVT. Techniques in Vascular and Interventional Radiology. 2004;7(2):79-85.
  • 15. Vedantham S, Vesely TM, Parti N, Darcy M, Hovsepian DM, Picus D. Lower extremity venous thrombolysis with adjunctive mechanical thrombectomy. Journal of Vascular and Interventional Radiology. 2002;13(10):1001-8.
  • 16. Lin PH, Zhou W, Dardik A, Mussa F, Kougias P, Hedayati N, et al. Catheter-direct thrombolysis versus pharmacomechanical thrombectomy for treatment of symptomatic lower extremity deep venous thrombosis. The American Journal of Surgery. 2006;192(6):782-8.
  • 17. Blackwood S, Dietzek AM. Pharmacomechanical thrombectomy: 2015 update. Expert Review of Cardiovascular Therapy. 2016;14(4):463-75.
  • 18. Kutsukata N, Mashiko K, Matsumoto H, Hara Y, Sakamoto Y, Yokota H, et al. Surgical venous thrombectomy for Japanese patients with acute deep vein thrombosis: a review of 5 years' experience. Journal of Nippon Medical School. 2010;77(3):155-9.
  • 19. Kasirajan K, Milner R, Chaikof EL. Combination therapies for deep venous thrombosis. Seminars in Vascular Surgery. 2006;19(2):116-21.
  • 20. Karthikesalingam A, Young EL, Hinchliffe RJ, Loftus IM, Thompson MM, Holt PJE. A systematic review of percutaneous mechanical thrombectomy in the treatment of deep venous thrombosis. European Journal of Vascular and Endovascular Surgery. 2011;41(4):554-65.
  • 21. Arko FR, Davis CM, Murphy EH, Smith ST, Timaran CH, Modrall JG, et al. Aggressive percutaneous mechanical thrombectomy of deep venous thrombosis: early clinical results. Archives of Surgery. 2007;142(6):513-9.
There are 21 citations in total.

Details

Primary Language English
Subjects Surgery
Journal Section Research article
Authors

Ferit Kasimzade 0000-0003-3646-3181

Fatih Ada 0000-0002-6953-5906

Özhan Karataş 0000-0002-2778-8059

Publication Date September 1, 2021
Published in Issue Year 2021 Volume: 5 Issue: 9

Cite

APA Kasimzade, F., Ada, F., & Karataş, Ö. (2021). Evaluation of ultrasonic intravascular thrombectomy system on a rabbit model in the treatment of deep vein thrombosis. Journal of Surgery and Medicine, 5(9), 921-923. https://doi.org/10.28982/josam.974368
AMA Kasimzade F, Ada F, Karataş Ö. Evaluation of ultrasonic intravascular thrombectomy system on a rabbit model in the treatment of deep vein thrombosis. J Surg Med. September 2021;5(9):921-923. doi:10.28982/josam.974368
Chicago Kasimzade, Ferit, Fatih Ada, and Özhan Karataş. “Evaluation of Ultrasonic Intravascular Thrombectomy System on a Rabbit Model in the Treatment of Deep Vein Thrombosis”. Journal of Surgery and Medicine 5, no. 9 (September 2021): 921-23. https://doi.org/10.28982/josam.974368.
EndNote Kasimzade F, Ada F, Karataş Ö (September 1, 2021) Evaluation of ultrasonic intravascular thrombectomy system on a rabbit model in the treatment of deep vein thrombosis. Journal of Surgery and Medicine 5 9 921–923.
IEEE F. Kasimzade, F. Ada, and Ö. Karataş, “Evaluation of ultrasonic intravascular thrombectomy system on a rabbit model in the treatment of deep vein thrombosis”, J Surg Med, vol. 5, no. 9, pp. 921–923, 2021, doi: 10.28982/josam.974368.
ISNAD Kasimzade, Ferit et al. “Evaluation of Ultrasonic Intravascular Thrombectomy System on a Rabbit Model in the Treatment of Deep Vein Thrombosis”. Journal of Surgery and Medicine 5/9 (September 2021), 921-923. https://doi.org/10.28982/josam.974368.
JAMA Kasimzade F, Ada F, Karataş Ö. Evaluation of ultrasonic intravascular thrombectomy system on a rabbit model in the treatment of deep vein thrombosis. J Surg Med. 2021;5:921–923.
MLA Kasimzade, Ferit et al. “Evaluation of Ultrasonic Intravascular Thrombectomy System on a Rabbit Model in the Treatment of Deep Vein Thrombosis”. Journal of Surgery and Medicine, vol. 5, no. 9, 2021, pp. 921-3, doi:10.28982/josam.974368.
Vancouver Kasimzade F, Ada F, Karataş Ö. Evaluation of ultrasonic intravascular thrombectomy system on a rabbit model in the treatment of deep vein thrombosis. J Surg Med. 2021;5(9):921-3.
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