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Evaluation of Echocardiographic Right Ventricular Deformation Parameters in Patients with Chronic Obstructive Pulmonary Disease

Year 2018, Volume: 21 Issue: 2, 163 - 168, 19.08.2018

Abstract

Introduction: This study
aimed to evaluate patients with chronic obstructive pulmonary disease (COPD)
who did not have clinical signs of right ventricular (RV) failure using
two-dimensional speckle-tracking of RV geometry and functions at rest in
comparison to healthy subjects.

Patients and Methods:
The
study population comprised 28 patients with COPD and 24 healthy subjects with
similar demographic characteristics who were followed up at the Department of
Chest Diseases of Kafkas University in 2014.

Results:
Conventional echocardiographic parameters, except for mean pulmonary artery
pressure, RV free wall thickness, and RV free wall strain parameters, were
similar between the groups. RV free wall strain parameters in the COPD group,
including RV free wall basal, mid, and apical strain values, were significantly
lower than those in the control group (p< 0.05 for each comparison). A
statistically significant negative correlation was observed between the mean
pulmonary artery pressure and the RV free wall basal, mid, and apical strain
values.







Conclusion: We concluded that RV strain
parameters may be superior to conventional echocardiographic methods for
assessing RV dysfunction prior to clinically evident RV failure.

References

  • 1. Almagro P, Barreiro B, de Echagüen AO, Quintana S, Carballeira MR, Heredia JL, et al. Risk factors for hospital readmission in patients with chronic obstructive pulmonary disease. Respiration 2006;73:311-7.
  • 2. Peinado VI, Barberà JA, Abate P, Ramírez J, Roca J, Santos S, et al. Inflammatory reaction in pulmonary muscular arteries of patients with mild chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;159:1605-11.
  • 3. Peinado VI, Barberà JA, Ramírez J, Gómez FP, Roca J, Jover L, et al. Endothelial dysfunction in pulmonary arteries of patients with mild COPD. Am J Physiol 1998;274:L908-13.
  • 4. Cuttica MJ, Shah SJ, Rosenberg SR, Orr R, Beussink L, Dematte JE, et al. Right heart structural changes are independently associated with exercise capacity in non-severe COPD. PLoS One 2011;6:e29069.
  • 5. Burgess MI, Mogulkoc N, Bright-Thomas RJ, Bishop P, Egan JJ, Ray SG. Comparison of echocardiographic markers of right ventricular function in determining prognosis in chronic pulmonary disease. J Am Soc Echocardiogr 2002;15:633-9.
  • 6. Gómez FP, Rodriguez-Roisin R. Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines for chronic obstructive pulmonary disease. Curr Opin Pulm Med 2002;8:81-6.
  • 7. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 2005;18:1440-63.
  • 8. Sabit R, Bolton CE, Fraser AG, Edwards JM, Edwards PH, Ionescu AA, et al. Sub-clinical left and right ventricular dysfunction in patients with COPD. Respir Med 2010;104:1171-8.
  • 9. Tayyareci Y, Tayyareci G, Tastan CP, Bayazit P, Nisanci Y. Early diagnosis of right ventricular systolic dysfunction by tissue Doppler derived isovolumic myocardial acceleration in patients with chronic obstructive pulmonary disease. Echocardiography 2009;26:1026-35.
  • 10. Hardegree EL, Sachdev A, Villarraga HR, Frantz RP, McGoon MD, Kushwaha SS, et al. Role of serial quantitative assessment of right ventricular function by strain in pulmonary arterial hypertension. Am J Cardiol 2013;111:143-8.
  • 11. Fukuda Y, Tanaka H, Sugiyama D, Ryo K, Onishi T, Fukuya H, et al. Utility of right ventricular free wall speckle-tracking strain for evaluation of right ventricular performance in patients with pulmonary hypertension. J Am Soc Echocardiogr 2011;24:1101-8.
  • 12. Vitarelli A, Conde Y, Cimino E, Stellato S, D’orazio S, D’angeli I, et al. Assessment of right ventricular function by strain rate imaging in chronic obstructive pulmonary disease. Eur Respir J 2006;27:268-75.
  • 13. Weitzenblum E, Chaouat A, Kessler R. Pulmonary hypertension in chronic obstructive pulmonary disease. Pneumonol Alergol Pol 2013;81:390-8.
  • 14. Fishman AP. Hypoxia on the pulmonary circulation. How and where it acts. Circ Res 1976;38:221-31.

Kronik Obstrüktif Akciğer Hastalığı Olan Hastalarda Ekokardiyografik Sağ Ventrikül Deformasyon Parametrelerinin Değerlendirilmesi

Year 2018, Volume: 21 Issue: 2, 163 - 168, 19.08.2018

Abstract

Giriş: Çalışmamızda klinik sağ ventrikül (SV) yetersizlik
bulguları olmayan kronik obstrüktif akciğer hastalığı (KOAH)’na sahip hastaları
sağlıklı bireylerle karşılaştırarak istirahatte SV geometrisi ve fonksiyolarını
iki boyutlu speckle-tracking kullanarak değerlendirmeyi amaçladık.



Hastalar ve Yöntem: Çalışma popülasyonunu, Kafkas
Üniversitesi Gögüs Hastalıkları Kliniğinde 2014 yılında ayaktan takip edilen
daha öncesinde KOAH tanısı olup klinik SV yetmezliği bulgusu olmayan 28 hasta
ve  benzer demografik özellikler taşıyan
24 sağlıklı birey oluşturmuştur.



Bulgular: Konvansiyonel ekokardiyografik özelliklerinden ortalama
pulmoner arter basıncı, SV serbest duvar kalınlığı ve SV serbest duvar strain
parametreleri haricindeki parametreler gruplar arasında benzerdi. KOAH grubunda
SV serbest duvar strain parametrelerinden; SV serbest duvar bazal, mid ve
apikal strain değerleri  kontrol grubuna
kıyasla daha düşük saptandı (her karşılaştırma için p< 0.05 idi). Ortalama
pulmoner arter basıncı  ve sırası ile
SV  serbest duvar bazal, mid ve apikal
strain değerleri arasında  istatistiksel
olarak anlamlı negatif korelasyon izlendi.



Sonuç: Çalışmamızın sonucuna göre
KOAH hastalarında olan SV disfonksiyonunu SV strain parametrelerinin
konvansiyonel ekokardiyografik yöntemlerden daha erken tespit ettiğini
saptadık.

References

  • 1. Almagro P, Barreiro B, de Echagüen AO, Quintana S, Carballeira MR, Heredia JL, et al. Risk factors for hospital readmission in patients with chronic obstructive pulmonary disease. Respiration 2006;73:311-7.
  • 2. Peinado VI, Barberà JA, Abate P, Ramírez J, Roca J, Santos S, et al. Inflammatory reaction in pulmonary muscular arteries of patients with mild chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;159:1605-11.
  • 3. Peinado VI, Barberà JA, Ramírez J, Gómez FP, Roca J, Jover L, et al. Endothelial dysfunction in pulmonary arteries of patients with mild COPD. Am J Physiol 1998;274:L908-13.
  • 4. Cuttica MJ, Shah SJ, Rosenberg SR, Orr R, Beussink L, Dematte JE, et al. Right heart structural changes are independently associated with exercise capacity in non-severe COPD. PLoS One 2011;6:e29069.
  • 5. Burgess MI, Mogulkoc N, Bright-Thomas RJ, Bishop P, Egan JJ, Ray SG. Comparison of echocardiographic markers of right ventricular function in determining prognosis in chronic pulmonary disease. J Am Soc Echocardiogr 2002;15:633-9.
  • 6. Gómez FP, Rodriguez-Roisin R. Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines for chronic obstructive pulmonary disease. Curr Opin Pulm Med 2002;8:81-6.
  • 7. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 2005;18:1440-63.
  • 8. Sabit R, Bolton CE, Fraser AG, Edwards JM, Edwards PH, Ionescu AA, et al. Sub-clinical left and right ventricular dysfunction in patients with COPD. Respir Med 2010;104:1171-8.
  • 9. Tayyareci Y, Tayyareci G, Tastan CP, Bayazit P, Nisanci Y. Early diagnosis of right ventricular systolic dysfunction by tissue Doppler derived isovolumic myocardial acceleration in patients with chronic obstructive pulmonary disease. Echocardiography 2009;26:1026-35.
  • 10. Hardegree EL, Sachdev A, Villarraga HR, Frantz RP, McGoon MD, Kushwaha SS, et al. Role of serial quantitative assessment of right ventricular function by strain in pulmonary arterial hypertension. Am J Cardiol 2013;111:143-8.
  • 11. Fukuda Y, Tanaka H, Sugiyama D, Ryo K, Onishi T, Fukuya H, et al. Utility of right ventricular free wall speckle-tracking strain for evaluation of right ventricular performance in patients with pulmonary hypertension. J Am Soc Echocardiogr 2011;24:1101-8.
  • 12. Vitarelli A, Conde Y, Cimino E, Stellato S, D’orazio S, D’angeli I, et al. Assessment of right ventricular function by strain rate imaging in chronic obstructive pulmonary disease. Eur Respir J 2006;27:268-75.
  • 13. Weitzenblum E, Chaouat A, Kessler R. Pulmonary hypertension in chronic obstructive pulmonary disease. Pneumonol Alergol Pol 2013;81:390-8.
  • 14. Fishman AP. Hypoxia on the pulmonary circulation. How and where it acts. Circ Res 1976;38:221-31.
There are 14 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Original Investigations
Authors

Yavuz Karabağ

Bahattin Balcı This is me

Yüksel Kaya This is me

Publication Date August 19, 2018
Published in Issue Year 2018 Volume: 21 Issue: 2

Cite

Vancouver Karabağ Y, Balcı B, Kaya Y. Kronik Obstrüktif Akciğer Hastalığı Olan Hastalarda Ekokardiyografik Sağ Ventrikül Deformasyon Parametrelerinin Değerlendirilmesi. Koşuyolu Heart Journal. 2018;21(2):163-8.