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Prolonged QT with Multiple-Causation and its Succesful Multistage Therapy

Year 2017, Volume: 20 Issue: 3, 265 - 268, 03.12.2017

Abstract

Prolonged
QT (PQT) is a myocardial repolarization disorder characterized by a
prolongation of the QT and a propensity to tachyarrhythmias, which may lead to
torsades de pointes ventricular tachycardia (TdPVT), polymorphic ventricular
tachycardia (PVT), and ventricular fibrillation. There are two forms of the
disorder, including congenital and acquired PQT. There are many drugs and
electrolyte disturbances that may lead to acquired form of PQT. Treatment of
these two types of PQT at acute statement is similar. We report the current
succesful therapies consisting of atrial pacing, lidocaine, and mexiletine for
a PQT patient.

References

  • 1. Schwartz PJ, Moss AJ, Vincent GM. Diagnostic criteria for the long QT syndrome: an update. Circulation 1993;88:782-4.
  • 2. Jorens PG, Van Den Heuvel PA, Ranquin REF, Van Den Branden FA, Parizel GA. Amiodarone induced torsades de pointe: Report of three cases and review of literature. Acta Cardiol 1989;5:411-21.
  • 3. Mattioni TA, Zheutlin TA, Sarmiento JJ, Parker M, Lesch M, Kehoe RF. Amiodarone in patients with previous drug-mediated torsade de pointes: Long-term safety and efficacy. Ann Intern Med 1989;111:574-80
  • 4. Eldar M, Griffin JC, Abbott J, Benditt D, Bhandari A, Herre JM, et al. Permanent cardiac pacing in patients with the long QT syndrome. J Am Coll Cardiol 1987;10:600-7.
  • 5. Rickards AF, Norman J. Relation between QT interval and heart rate. New design of physiologically adaptive cardiac pacemaker. Br Heart J 1981;45:56-61.
  • 6. Yamada S, Kuga K, Yamaguchi I. Torsade de pointes induced by intravenous and long-term oral amiodarone therapy in a patient with dilated cardiomyopathy. Jpn Circ J 2001;65:236-8.
  • 7. Park J, Kim SK, Pak HN. A case of Long QT syndrome type 3 aggravated by beta-blockers and alleviated by mexiletine: the role of epinephrine provocation test: Yonsei Med J 2013;54:529-33.

Çok Sebepli Uzamış QT ve Basamaklı Bir Şekilde Başarılı Tedavisi

Year 2017, Volume: 20 Issue: 3, 265 - 268, 03.12.2017

Abstract

Uzamış
QT (UQT), bir miyokardiyal repolarizasyon bozukluğu olup QT aralığının uzaması
ve taşiaritmilerle karakterizedir. Bu durum; torsades depointes ventriküler
taşikardisi (TdPVT), polimorfik ventriküler taşikardi (PVT) ve ventriküler
fibrilasyona neden olabilir. Konjenital ve edinsel olmak üzere iki formu
mevcuttur. Bu hastalığın edinsel formuna birçok ilaç veya elektrolit
dengesizliği sebep olabilir. Edinsel ve konjenital formlarının akut dönemde
tedavileri benzerdir. Biz olgu sunumumuzda tedaviye dirençli bir UQT hastasına
yapılan; atriyal uyarma, lidokain ve meksiletin gibi güncel tedavi
yöntemlerinin başarılı bir şekilde uygulanışını aktarmaya çalıştık.

References

  • 1. Schwartz PJ, Moss AJ, Vincent GM. Diagnostic criteria for the long QT syndrome: an update. Circulation 1993;88:782-4.
  • 2. Jorens PG, Van Den Heuvel PA, Ranquin REF, Van Den Branden FA, Parizel GA. Amiodarone induced torsades de pointe: Report of three cases and review of literature. Acta Cardiol 1989;5:411-21.
  • 3. Mattioni TA, Zheutlin TA, Sarmiento JJ, Parker M, Lesch M, Kehoe RF. Amiodarone in patients with previous drug-mediated torsade de pointes: Long-term safety and efficacy. Ann Intern Med 1989;111:574-80
  • 4. Eldar M, Griffin JC, Abbott J, Benditt D, Bhandari A, Herre JM, et al. Permanent cardiac pacing in patients with the long QT syndrome. J Am Coll Cardiol 1987;10:600-7.
  • 5. Rickards AF, Norman J. Relation between QT interval and heart rate. New design of physiologically adaptive cardiac pacemaker. Br Heart J 1981;45:56-61.
  • 6. Yamada S, Kuga K, Yamaguchi I. Torsade de pointes induced by intravenous and long-term oral amiodarone therapy in a patient with dilated cardiomyopathy. Jpn Circ J 2001;65:236-8.
  • 7. Park J, Kim SK, Pak HN. A case of Long QT syndrome type 3 aggravated by beta-blockers and alleviated by mexiletine: the role of epinephrine provocation test: Yonsei Med J 2013;54:529-33.
There are 7 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Case Reports
Authors

Muhammed Keskin

Ahmet Taha Alper This is me

Ceyhan Türkkan This is me

Ahmet İlker Tekkeşin This is me

Publication Date December 3, 2017
Published in Issue Year 2017 Volume: 20 Issue: 3

Cite

Vancouver Keskin M, Alper AT, Türkkan C, Tekkeşin Aİ. Çok Sebepli Uzamış QT ve Basamaklı Bir Şekilde Başarılı Tedavisi. Koşuyolu Heart Journal. 2017;20(3):265-8.