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Could Hemogram Parameters Be Useful Biomarkers for The Diagnosis of Impaired Glucose Tolerance ?

Year 2022, Volume: 14 Issue: 1, 9 - 12, 14.03.2022
https://doi.org/10.18521/ktd.843666

Abstract

Objective: Elevated blood glucose may be affect complete blood count parameters. In this study, we compared the hemogram parameters of healthy individuals and cases with impaired glucose tolerance.
Method: We examineted 134 patients with impaired glucose tolerance and 30 healthy cases. Patients files were evaluated retrospectively and the levels of hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, red blood cell, red cell distribution wide, mean platelet volume, platelet distribution wide, leukocycte, neutrophil, lymphocycte, platelet, and hemoglobin A1c were recorded. Control and patient groups were compared in terms of these parameters with student T test. In addition, the relationship between hemoglobin A1c value and complete blood count parameters were determined in patients with impaired glucose tolerance.
Results: There was no significantly difference between study and control groups in terms of hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, red blood cell count, red cell distrubition wide, leukocycte, neutrophil, lymphocycte, platelet levels. The mean platelet volume and platelet distribution wide values were significantly higher in the patient group than the control group (p value: 0.002, p value: 0.04 respectively).
Conclusion: Complete blood count is an easy, inexpensive test that can be performed in most hospitals. If our study results are supported by other studies, some hemogram parameters may be used to diagnose of impaired glucose tolerance.

References

  • Referans1. Zuberi BF, Akhtar N, Afsar S. Comparison of mean platelet volume in patients with diabetes mellitus, impaired fasting glucose and non‐diabetic subjects. Singapore Med J. 2008;49:114–116. Referans2. Chen LK, Ming-Hsien L, Zhi-Jun C, Shinn-Jang H, Chiou ST. Association of insulin resistance and hematologic parameters: study of a middle-aged and elderly Chinese population in Taiwan. Chin Med Assoc. 2006;69(6):248–253.

Bozulmuş Glukoz Toleransının Tanısında Hemogram Parametreleri Biyobelirteç Olarak Kullanılabilir mi?

Year 2022, Volume: 14 Issue: 1, 9 - 12, 14.03.2022
https://doi.org/10.18521/ktd.843666

Abstract

Amaç: Yüksek kan şekeri, tam kan sayımı parametrelerini etkileyebilir. Biz bu çalışmada sağlıklı bireylerin ve bozulmuş glukoz toleranslı olguların hemogram parametrelerini karşılaştırdık.
Gereç ve Yöntem: Biz bozulmuş glukoz toleranslı 134 hasta ve 30 sağlıklı bireyi inceledik. Hasta dosyaları retrospektif olarak değerlendirildi ve hemoglobin, hematokrit, ortalama eritrosit hacmi, ortalama eritrosit hemoglobini, kırmızı kan hücresi, eritrosit dağılım genişliği, ortalama trombosit hacmi, trombosit dağılım genişliği, lökosit, nötrofil, lenfosit, trombosit ve hemoglobin A1c düzeyleri kaydedildi . Kontrol ve hasta grupları bu parametreler açısından student T testi ile karşılaştırıldı.
Bulgular: Çalışma ve kontrol grupları arasında hemoglobin, hematokrit, ortalama eritrosit hacmi, ortalama eritrosit hemoglobini, kırmızı kan hücresi sayısı, eritrosit dağılım genişliği, lökosit, nötrofil, lenfosit, trombosit düzeyleri açısından anlamlı fark yoktu. Hasta grubunda ortalama trombosit hacmi ve trombosit dağılım genişliği değerleri kontrol grubuna göre anlamlı olarak yüksekti (sırasıyla p değeri: 0.002, p değeri: 0.04).
Sonuç: Tam kan sayımı, çoğu hastanede yapılabilen kolay ve ucuz bir testtir. Çalışma sonuçlarımız başka çalışmalarla desteklenirse, bozulmuş glukoz toleransını teşhis etmek için bazı hemogram parametreleri kullanılabilir.

References

  • Referans1. Zuberi BF, Akhtar N, Afsar S. Comparison of mean platelet volume in patients with diabetes mellitus, impaired fasting glucose and non‐diabetic subjects. Singapore Med J. 2008;49:114–116. Referans2. Chen LK, Ming-Hsien L, Zhi-Jun C, Shinn-Jang H, Chiou ST. Association of insulin resistance and hematologic parameters: study of a middle-aged and elderly Chinese population in Taiwan. Chin Med Assoc. 2006;69(6):248–253.
There are 1 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Articles
Authors

Gülden Sincan 0000-0002-7671-7628

İlyas Öztürk 0000-0003-3742-0503

Suat Sincan 0000-0003-3170-2753

Fuat Erdem 0000-0002-0377-7291

Ahmet Veli Şanibaş 0000-0002-7824-6284

Publication Date March 14, 2022
Acceptance Date November 18, 2021
Published in Issue Year 2022 Volume: 14 Issue: 1

Cite

APA Sincan, G., Öztürk, İ., Sincan, S., Erdem, F., et al. (2022). Could Hemogram Parameters Be Useful Biomarkers for The Diagnosis of Impaired Glucose Tolerance ?. Konuralp Medical Journal, 14(1), 9-12. https://doi.org/10.18521/ktd.843666
AMA Sincan G, Öztürk İ, Sincan S, Erdem F, Şanibaş AV. Could Hemogram Parameters Be Useful Biomarkers for The Diagnosis of Impaired Glucose Tolerance ?. Konuralp Medical Journal. March 2022;14(1):9-12. doi:10.18521/ktd.843666
Chicago Sincan, Gülden, İlyas Öztürk, Suat Sincan, Fuat Erdem, and Ahmet Veli Şanibaş. “Could Hemogram Parameters Be Useful Biomarkers for The Diagnosis of Impaired Glucose Tolerance ?”. Konuralp Medical Journal 14, no. 1 (March 2022): 9-12. https://doi.org/10.18521/ktd.843666.
EndNote Sincan G, Öztürk İ, Sincan S, Erdem F, Şanibaş AV (March 1, 2022) Could Hemogram Parameters Be Useful Biomarkers for The Diagnosis of Impaired Glucose Tolerance ?. Konuralp Medical Journal 14 1 9–12.
IEEE G. Sincan, İ. Öztürk, S. Sincan, F. Erdem, and A. V. Şanibaş, “Could Hemogram Parameters Be Useful Biomarkers for The Diagnosis of Impaired Glucose Tolerance ?”, Konuralp Medical Journal, vol. 14, no. 1, pp. 9–12, 2022, doi: 10.18521/ktd.843666.
ISNAD Sincan, Gülden et al. “Could Hemogram Parameters Be Useful Biomarkers for The Diagnosis of Impaired Glucose Tolerance ?”. Konuralp Medical Journal 14/1 (March 2022), 9-12. https://doi.org/10.18521/ktd.843666.
JAMA Sincan G, Öztürk İ, Sincan S, Erdem F, Şanibaş AV. Could Hemogram Parameters Be Useful Biomarkers for The Diagnosis of Impaired Glucose Tolerance ?. Konuralp Medical Journal. 2022;14:9–12.
MLA Sincan, Gülden et al. “Could Hemogram Parameters Be Useful Biomarkers for The Diagnosis of Impaired Glucose Tolerance ?”. Konuralp Medical Journal, vol. 14, no. 1, 2022, pp. 9-12, doi:10.18521/ktd.843666.
Vancouver Sincan G, Öztürk İ, Sincan S, Erdem F, Şanibaş AV. Could Hemogram Parameters Be Useful Biomarkers for The Diagnosis of Impaired Glucose Tolerance ?. Konuralp Medical Journal. 2022;14(1):9-12.