Abstract
Celiac disease is a systemic autoimmune disease that frequently presents with clinical manifestations such as malnutrition, abdominal distension and diarrhea in childhood. With the increase in the incidence of celiac disease in recent years, differences in findings in patients at the time of diagnosis have been observed. While classical symptoms are common in younger age groups, differences in symptoms are more commonly observed in the adolescent age group. These findings often include abdominal pain, treatment-resistant iron deficiency anemia, elevated transaminase levels and diarrhea. Celiac disease should be considered in the differential diagnosis, even when malnutrition is not evident in such patients. In this case report, we present a case of an obese patient diagnosed with celiac disease, who experienced intermittent abdominal pain.
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References
- Husby S, Koletzko S, Korponay-Szabó I, Kurppa K, Mearin ML, Ribes-Koninckx C, et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease 2020. J Pediatr Gastroenterol Nutr. 2020;70(1):141-56.
- Venkatasubramani N, Telega G, Werlin SL. Obesity in pediatric celiac disease. J Pediatr Gastroenterol Nutr. 2010;51(3):295-7.
- Güven B, Sağ E, Çakır M, Is clinical spectrum of celiac disease changing in children? Türkiye Klinikleri J Pediatr. 2020;29(3):133-8
- Drosdak A, Satyavada S, Ismail M, Shah R, Cooper G. Obesity prevalence in celiac disease in the United States from 2014 to 2018. Int J Obes (Lond). 2022;46(2):441-3.
- Diamanti A, Capriati T, Basso MS, Panetta F, Laurora Vmdc, Bellucci F, et al. Celiac disease and overweight in children: An update. Nutrients. 2014;6(1):207-20.
- Semeraro LA, Barwick KW, Gryboski JD. Obesity in Celiac sprue. J Clin Gastroenterol. 1986;8(2):177- 80.
- Telega G, Bennet TR, Werlin S. Emerging new clinical patterns in the presentation of celiac disease. Arch Pediatr Adolesc Med. 2008;162(2):164-8.
- Llorente-Alonso M, Fernandez-Acenero MJ, Sebastian M. Gluten intolerance: Gender and age- related features. Can J Gastroenterol. 2006;20(11):719-22.
- Pals M, Myleus A, Norström F, Hammarroth S, Högberg L, Rosen A, et al. Body mass index is not a reliable tool in predicting celiac disease in children. BMC Pediatrics. 2014;14:165.
- Valletta E, Fornaro M, Cipolli M, Conte S, Bissolo F, Danchielli C. Celiac disease and obesity: Need for nutritional follow-up after diagnosis. European Journal of Clinical Nutrition. 2010;64(11):1371-2.
- Capriati T, Francavilla R, Ferretti F, Castellaneta S, Ancinelli M, Diamanti A. The overweight: A rare presentation of celiac disease. European Journal of Clinical Nutrition. 2016;70(2):282-4.
- Franzese A, Lannucci MP, Valerio G, Cincimarra E, Spaziano M, Mandato C, et al. Atypical celiac disease presenting as obesity-related liver dysfunction. J Pediatr Gastroenterol Nutr. 2001;33(3):329-32.
Abstract
Çölyak hastalığı, çocukluk çağında sıklıkla malnütrisyon bulguları, karında şişlik, ishal gibi klinik tablolar ile başvuruya sebep olan sistemik bir otoimmun hastalıktır. Son yıllarda çölyak hastalığının insidansının artmasıyla birlikte tanı anında hastalarda saptanan bulgulardaki farklılıklar dikkat çekmektedir. Küçük yaşlarda bu klasik semptomlarla başvuru daha sık olurken, özellikle adölesan yaş grubunda bu bulgulardaki farklılıkların daha çok olduğu izlenmektedir. Bu bulguların sıklıkla karın ağrısı, tedaviye dirençli demir eksikliği anemisi, transaminaz yüksekliği veya ishal olduğu belirtilmiştir. Böyle hastalarda malnutrisyon bulunmasa da çölyak hastalığının ayırıcı tanılar arasında bulunması gerekmektedir. Bu olgu sunumunda aralıklı olarak karın ağrısı şikayeti olan, çölyak hastalığı tanısı alan obez hasta sunulmuş ve literatür bilgileriyle tartışılmıştır.
Keywords
Project Number
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References
- Husby S, Koletzko S, Korponay-Szabó I, Kurppa K, Mearin ML, Ribes-Koninckx C, et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease 2020. J Pediatr Gastroenterol Nutr. 2020;70(1):141-56.
- Venkatasubramani N, Telega G, Werlin SL. Obesity in pediatric celiac disease. J Pediatr Gastroenterol Nutr. 2010;51(3):295-7.
- Güven B, Sağ E, Çakır M, Is clinical spectrum of celiac disease changing in children? Türkiye Klinikleri J Pediatr. 2020;29(3):133-8
- Drosdak A, Satyavada S, Ismail M, Shah R, Cooper G. Obesity prevalence in celiac disease in the United States from 2014 to 2018. Int J Obes (Lond). 2022;46(2):441-3.
- Diamanti A, Capriati T, Basso MS, Panetta F, Laurora Vmdc, Bellucci F, et al. Celiac disease and overweight in children: An update. Nutrients. 2014;6(1):207-20.
- Semeraro LA, Barwick KW, Gryboski JD. Obesity in Celiac sprue. J Clin Gastroenterol. 1986;8(2):177- 80.
- Telega G, Bennet TR, Werlin S. Emerging new clinical patterns in the presentation of celiac disease. Arch Pediatr Adolesc Med. 2008;162(2):164-8.
- Llorente-Alonso M, Fernandez-Acenero MJ, Sebastian M. Gluten intolerance: Gender and age- related features. Can J Gastroenterol. 2006;20(11):719-22.
- Pals M, Myleus A, Norström F, Hammarroth S, Högberg L, Rosen A, et al. Body mass index is not a reliable tool in predicting celiac disease in children. BMC Pediatrics. 2014;14:165.
- Valletta E, Fornaro M, Cipolli M, Conte S, Bissolo F, Danchielli C. Celiac disease and obesity: Need for nutritional follow-up after diagnosis. European Journal of Clinical Nutrition. 2010;64(11):1371-2.
- Capriati T, Francavilla R, Ferretti F, Castellaneta S, Ancinelli M, Diamanti A. The overweight: A rare presentation of celiac disease. European Journal of Clinical Nutrition. 2016;70(2):282-4.
- Franzese A, Lannucci MP, Valerio G, Cincimarra E, Spaziano M, Mandato C, et al. Atypical celiac disease presenting as obesity-related liver dysfunction. J Pediatr Gastroenterol Nutr. 2001;33(3):329-32.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Services and Systems (Other) |
| Journal Section | Case Reports |
| Authors | |
| Project Number | - |
| Publication Date | December 26, 2023 |
| Submission Date | August 9, 2023 |
| Published in Issue | Year 2023 Volume: 25 Issue: 3 |
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Bu Dergi, Kırıkkale Üniversitesi Tıp Fakültesi Yayınıdır.