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SPLENİK ANJİOSARKOMANIN TANISI, TEDAVİSİ, RADYOLOJİK VE PATOLOJİK BULGULARI:OLGU SUNUMU

Year 2009, Volume: 22 Issue: 1, 56 - 58, 04.05.2015

Özgür Ekinci Özlem Okur Fikret Aksoy Gökhan Demiral Taner Evcimik Haydar Yalman Rafet Yiğitbaşı

Abstract

ÖZET Primer splenik anjiosarkomalar dalağın hematopoetik sistemle ilişkili olmayan en sık malign tümörleri olmasına karşın oldukça nadir görülmekte ve prognozu son derece kötüdür. Bu tümörlerin seyri oldukça agresif ve ölümcül olup yaygın metastazlar veya dalak rüptürü ile karşımıza çıkarlar. Kesin tanı ve tedavi cerrahi ile olur ve rüptür öncesi uygulanan splenektomi yaşam süresini anlamlı şekilde uzatır. Primer splenik anjiosarkomalı bir hastanın tanı, radyolojik patolojik bulgular ve tedavisini sunuyoruz.

Anahtar Kelimeler: Anjiosarkoma, Dalak, İmmünhistokimya, Görüntüleme

Keywords

Anjiosarkoma Dalak İmmünhistokimya Görüntüleme

References

  • Wick MR, Scheithaver BW, Smith SI. Primary
  • nonlymphoreticular malignant neoplasms of spleen.
  • Am J Surg Pathol 1982; 6:229-242.
  • Rosai J. Spleen. In: Rosai J. Ed. Rosai and
  • Ackerman’s Surgical Pathology. Volume 2. 9th ed.
  • Philadelphia: Mosby, 2004;:2036-2042.
  • Cotran RS, Kumar V, Robbins S Pathologic basis of
  • disease.5th ed. Philadelphia: W.B.Saunders, 1994:
  • -516.
  • Falk S, Krishan J, Meis JM. Primary angiosarcoma of
  • spleen: A clinicopathologic study of 40 cases. Am J
  • Surg Pathol 1993; 17:959-970.
  • Autry JR, Weitzner S. Hemangiosarcoma of spleen
  • with spontaneous rupture. Cancer 1975; 35:534-539.
  • Smith VC, Usaf MC, Eisenberg BL, et al. Primary
  • splenic angiosarcoma. Cancer 1985; 55:1625-1627.
  • Karakas HM, Demir M, Ozyılmaz F, Cakır B.
  • Primary angiosarcoma of spleen: in vivo and in vitro
  • MRI findings. Clin Imaging 2001; 25:192-196.
  • Wafula JM. Ultrasound and CT demonstration of
  • primary angiosarcoma of spleen. Br J Radiol 1985;
  • :903-907.
  • Karakaş HM., Tunçbilek N, Ökten ÖÖ. Splenic
  • abnormalities; an overview on sectional images.
  • Diagn Intervent Radiol 2005; 11:152-58.
  • Neuhauser TS, Derringer CA, Thompson LD, et.al.
  • Splenic angiosarcoma: A clinicopathologic and
  • immunophenotypic study of 28 cases. Mod Pathol
  • ; 13:978-987.

DIAGNOSIS, TREATMENT, RADIOLOGIC AND PATHOLOGIC FINDINGS OF SPLENIC ANGIOSARCOMA

Year 2009, Volume: 22 Issue: 1, 56 - 58, 04.05.2015

Özgür Ekinci Özlem Okur Fikret Aksoy Gökhan Demiral Taner Evcimik Haydar Yalman Rafet Yiğitbaşı

Abstract

Although primary splenic angiosarcomas are the most common malignant nonhematopoietic tumors of the spleen ,they are extremely rare tumors with very poor prognosis. These tumors are highly aggressive and lethal, present with widespread metastasis or splenic rupture. Definitive diagnosis and treatment is surgical and survival is significantly improved when splenectomy is performed prior to rupture. Diagnosis, radiologic and pathologic findings and treatment of a patient with primary splenic angiosarcoma are presented.

Keywords

Angiosarcoma Spleen Immunohistochemistry Imaging

References

  • Wick MR, Scheithaver BW, Smith SI. Primary
  • nonlymphoreticular malignant neoplasms of spleen.
  • Am J Surg Pathol 1982; 6:229-242.
  • Rosai J. Spleen. In: Rosai J. Ed. Rosai and
  • Ackerman’s Surgical Pathology. Volume 2. 9th ed.
  • Philadelphia: Mosby, 2004;:2036-2042.
  • Cotran RS, Kumar V, Robbins S Pathologic basis of
  • disease.5th ed. Philadelphia: W.B.Saunders, 1994:
  • -516.
  • Falk S, Krishan J, Meis JM. Primary angiosarcoma of
  • spleen: A clinicopathologic study of 40 cases. Am J
  • Surg Pathol 1993; 17:959-970.
  • Autry JR, Weitzner S. Hemangiosarcoma of spleen
  • with spontaneous rupture. Cancer 1975; 35:534-539.
  • Smith VC, Usaf MC, Eisenberg BL, et al. Primary
  • splenic angiosarcoma. Cancer 1985; 55:1625-1627.
  • Karakas HM, Demir M, Ozyılmaz F, Cakır B.
  • Primary angiosarcoma of spleen: in vivo and in vitro
  • MRI findings. Clin Imaging 2001; 25:192-196.
  • Wafula JM. Ultrasound and CT demonstration of
  • primary angiosarcoma of spleen. Br J Radiol 1985;
  • :903-907.
  • Karakaş HM., Tunçbilek N, Ökten ÖÖ. Splenic
  • abnormalities; an overview on sectional images.
  • Diagn Intervent Radiol 2005; 11:152-58.
  • Neuhauser TS, Derringer CA, Thompson LD, et.al.
  • Splenic angiosarcoma: A clinicopathologic and
  • immunophenotypic study of 28 cases. Mod Pathol
  • ; 13:978-987.
There are 29 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Case Reports
Authors

Özgür Ekinci This is me

Özlem Okur This is me

Fikret Aksoy This is me

Gökhan Demiral

Taner Evcimik This is me

Haydar Yalman This is me

Rafet Yiğitbaşı This is me

Publication Date May 4, 2015
Published in Issue Year 2009 Volume: 22 Issue: 1

Cite

APA Ekinci, Ö., Okur, Ö., Aksoy, F., Demiral, G., et al. (2015). DIAGNOSIS, TREATMENT, RADIOLOGIC AND PATHOLOGIC FINDINGS OF SPLENIC ANGIOSARCOMA. Marmara Medical Journal, 22(1), 56-58.
AMA Ekinci Ö, Okur Ö, Aksoy F, Demiral G, Evcimik T, Yalman H, Yiğitbaşı R. DIAGNOSIS, TREATMENT, RADIOLOGIC AND PATHOLOGIC FINDINGS OF SPLENIC ANGIOSARCOMA. Marmara Med J. August 2015;22(1):56-58.
Chicago Ekinci, Özgür, Özlem Okur, Fikret Aksoy, Gökhan Demiral, Taner Evcimik, Haydar Yalman, and Rafet Yiğitbaşı. “DIAGNOSIS, TREATMENT, RADIOLOGIC AND PATHOLOGIC FINDINGS OF SPLENIC ANGIOSARCOMA”. Marmara Medical Journal 22, no. 1 (August 2015): 56-58.
EndNote Ekinci Ö, Okur Ö, Aksoy F, Demiral G, Evcimik T, Yalman H, Yiğitbaşı R (August 1, 2015) DIAGNOSIS, TREATMENT, RADIOLOGIC AND PATHOLOGIC FINDINGS OF SPLENIC ANGIOSARCOMA. Marmara Medical Journal 22 1 56–58.
IEEE Ö. Ekinci, “DIAGNOSIS, TREATMENT, RADIOLOGIC AND PATHOLOGIC FINDINGS OF SPLENIC ANGIOSARCOMA”, Marmara Med J, vol. 22, no. 1, pp. 56–58, 2015.
ISNAD Ekinci, Özgür et al. “DIAGNOSIS, TREATMENT, RADIOLOGIC AND PATHOLOGIC FINDINGS OF SPLENIC ANGIOSARCOMA”. Marmara Medical Journal 22/1 (August 2015), 56-58.
JAMA Ekinci Ö, Okur Ö, Aksoy F, Demiral G, Evcimik T, Yalman H, Yiğitbaşı R. DIAGNOSIS, TREATMENT, RADIOLOGIC AND PATHOLOGIC FINDINGS OF SPLENIC ANGIOSARCOMA. Marmara Med J. 2015;22:56–58.
MLA Ekinci, Özgür et al. “DIAGNOSIS, TREATMENT, RADIOLOGIC AND PATHOLOGIC FINDINGS OF SPLENIC ANGIOSARCOMA”. Marmara Medical Journal, vol. 22, no. 1, 2015, pp. 56-58.
Vancouver Ekinci Ö, Okur Ö, Aksoy F, Demiral G, Evcimik T, Yalman H, Yiğitbaşı R. DIAGNOSIS, TREATMENT, RADIOLOGIC AND PATHOLOGIC FINDINGS OF SPLENIC ANGIOSARCOMA. Marmara Med J. 2015;22(1):56-8.