Research Article
Year 2019,
Volume: 5 Issue: 3, 180 - 185, 31.12.2019
Abstract
References
- Adamu MA, Weck MN, Gao L, Brenner H. Incidence of chronic atrophic gastritis: systematic review and meta-analysis of follow-up studies. Eur J Epidemiol. 2010;25:439–448.
- Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY et al. The effect of eradication of Helicobacter pylori on gastric cancer prevention in healthy asymptomatic populations. Helicobacter. 2018;23:e12464
- Carroll MR, Seaman HE, Halloran SP. Tests and investigations for colorectal cancer screening. Clin Biochem. 2014;47:921–939.
- Eusebi LH, Zagari RM, Bazzoli F. Epidemiology of Helicobacter pylori infection. Helicobacter. 2014;19 Suppl 1:1–5.
- Hooi JKY, Lai WY, Ng WK, Suen MMY, Underwood FE, Tanyingoh D et al. Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta Analysis. Gastroenterology. 2017;153(2):420–9. 10.1053/j.gastro.2017.04.022 Ioannou GN, Rockey DC, Bryson CL, Weiss NS. Iron deficiency and gastrointestinal malignancy: a population-based cohort study. Am J Med. 2002;113(4):276–280.
- Joaquín Cubiella , Jayne Digby, Lorena Rodríguez-Alonso, Pablo Vega, María Salve, Marta Díaz-Ondina et al. The fecal hemoglobin concentration, age and sex test score: Development and external validation of a simple prediction tool for colorectal cancer detection in symptomatic patients, Int. J. Cancer:140, 2201–2211 (2017)VC2017 UICC
- Lansdorp-Vogelaar I, van Ballegooijen M, Boer R, Zauber A, Habbema JD. A novel hypothesis on the sensitivity of the fecal occult blood test: Results of a joint analysis of 3 randomized controlled trials. Cancer. 2009;115:2410–2419.
- Lee YC, Chiang TH, Chou CK, Tu YK, Liao WC, Wu MS et al. Association Between Helicobacter pylori Eradication and Gastric Cancer Incidence: A Systematic Review and Meta-analysis. Gastroenterology. 2016;150:1113–1124.e5
- Mandel JS, Church TR, Bond JH, Ederer F, Geisser MS, Mongin SJ, et al. The effect of fecal occult-blood screening on the incidence of colorectal cancer. New Engl J Med. 2000;343(22):1603–1607.
- Marshall B.J., Warren J.R. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984;1:1311–1315. doi: 10.1016/S0140-6736(84)91816-6.
- Qaseem A, Denberg TD, Hopkins RH Jr, Humphrey LL, Levine J, Sweet DE et al. Screening for colorectal cancer: a guidance statement from the American College of Physicians. Ann Int Med. 2012;156(5):378–386.
- Rodríguez-Alonso L, Rodríguez-Moranta F, Ruiz-Cerulla A, Lobatón T, Arajol C, Binefa G et al. An urgent referral strategy for symptomatic patients with suspected colorectal cancer based on a quantitative immunochemical faecal occult blood test. Dig Liver Dis 2015;47:797–804.
- Sabatino SA, White MC, Thompson TD, Klabunde CN; Centers for Disease Control and Prevention (CDC) Cancer screening test use - United States, 2013. MMWR Morb Mortal Wkly Rep. 2015;64:464–468.
- Testoni P.A., Masci E., Marchi R., Guslandi M., Ronchi G., Tittobello A. Gastric cancer in chronic atrophic gastritis. Associated gastric ulcer adds no further risk. J. Clin. Gastroenterol. 1987;9:298–302. doi: 10.1097/00004836-198706000-00011.
- Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65:87–108.
- Uemura N., Okamoto S., Yamamoto S., Matsumura N., Yamaguchi S., Yamakido M. Et al.Helicobacter pylori infection and the development of gastric cancer. N. Engl. J. Med. 2001;345:784–789. doi: 10.1056/NEJMoa001999.
- Vannella L, Lahner E, Bordi C, Pilozzi E, Di Giulio E, Corleto VD et al. Reversal of atrophic body gastritis after H. pylori eradication at long-term follow-up. Dig Liver Dis. 2011;43:295–299.
- Von Karsa L, Patnick J, Segnan N, Atkin W, Halloran S, Lansdorp-Vogelaar I, et al. European Colorectal Cancer Screening Guidelines Working Group, European guidelines for quality assurance in colorectal cancer screening and diagnosis: overview and introduction to the full supplement publication. Endoscopy. 2013;45(1):51–59.
- Williams TGS, Cubiella J, Griffin SJ, Walter FM, Usher-Smith JA. Risk prediction models for colorectal cancer in people with symptoms: a systematic review. BMC Gastroenterol 2016;16:63.
- Zamani M, Ebrahimtabar F, Zamani V, Miller WH, Alizadeh-Navaei R, Shokri-Shirvani J et al. : Systematic review with meta-analysis: the worldwide prevalence of Helicobacter pylori infection. Aliment Pharmacol Ther. 2018;47(7):868–76. 10.1111/apt.14561
Investigation of Hemogram, Endoscopy, Demographic Properties of Patients Applied by Fecal Occult Blood Test Screening
Abstract
Objective: Colorectal cancer (CRC) is one of the most common
cancers in the world. Fecal occult blood test (FOBT) is easy and commonly used
test to its screening. The aim of this study was to investigate the demographic
characteristics, hemogram results and endoscopy and outcome status of the
patients who underwent FOBT on history and clinical suspicion and to contribute
to the literature.
Methods: 400 patients who were admitted to the general
surgery polyclinic between 01/12/2016 and 12/12/2017 in Ordu University Medical
Faculty Training and Research Hospital were evaluated retrospectively. The data
of 349 patients who underwent FOBT was reached. Age and sex, hemoglobin,
hematocrit, ferritin levels, upper and lower gastrointestinal endoscopy results
and pathology results of endoscopic biopsies were recorded.
Results: 38 (10.9%) with FOBT (+) and 311 (89.1%) with FOBT
(-) of 349 patients were detected. There was no statistically significant
difference between the two groups in terms of the average age (p = 0.27) and
gender (p = 0.26). There was a significant difference between the two groups in
terms of the rate of upper gastrointestinal endoscopy (p = 0.03). There was a
significant difference between the two groups in terms of the rate of
colonoscopy (p = 0.001). Malignancy was detected in 22,2% of FOBT (+) and in
1,63% of FOBT (-) group by colonoscopy. There was a statistically significant
difference between the two groups in terms of disease diagnoses (p = 0.001).
There was no statistically significant difference between the two groups in
terms of Helicobacter Pylori (H. pylori) (p = 0.31) and intestinal metaplasia (p = 0.44). There was a statistically
significant difference between the two groups in terms of Hb and Htc value (p=
0.05).
Conclusion: According to the results of FOBT, the application
of endoscopy to the patients who are required, provide to detect the
precancerous lesions as well as the malignancies of the upper and lower
gastrointestinal tract. Good knowledge of the importance of this test will
allow early detection of malignancy.
References
- Adamu MA, Weck MN, Gao L, Brenner H. Incidence of chronic atrophic gastritis: systematic review and meta-analysis of follow-up studies. Eur J Epidemiol. 2010;25:439–448.
- Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY et al. The effect of eradication of Helicobacter pylori on gastric cancer prevention in healthy asymptomatic populations. Helicobacter. 2018;23:e12464
- Carroll MR, Seaman HE, Halloran SP. Tests and investigations for colorectal cancer screening. Clin Biochem. 2014;47:921–939.
- Eusebi LH, Zagari RM, Bazzoli F. Epidemiology of Helicobacter pylori infection. Helicobacter. 2014;19 Suppl 1:1–5.
- Hooi JKY, Lai WY, Ng WK, Suen MMY, Underwood FE, Tanyingoh D et al. Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta Analysis. Gastroenterology. 2017;153(2):420–9. 10.1053/j.gastro.2017.04.022 Ioannou GN, Rockey DC, Bryson CL, Weiss NS. Iron deficiency and gastrointestinal malignancy: a population-based cohort study. Am J Med. 2002;113(4):276–280.
- Joaquín Cubiella , Jayne Digby, Lorena Rodríguez-Alonso, Pablo Vega, María Salve, Marta Díaz-Ondina et al. The fecal hemoglobin concentration, age and sex test score: Development and external validation of a simple prediction tool for colorectal cancer detection in symptomatic patients, Int. J. Cancer:140, 2201–2211 (2017)VC2017 UICC
- Lansdorp-Vogelaar I, van Ballegooijen M, Boer R, Zauber A, Habbema JD. A novel hypothesis on the sensitivity of the fecal occult blood test: Results of a joint analysis of 3 randomized controlled trials. Cancer. 2009;115:2410–2419.
- Lee YC, Chiang TH, Chou CK, Tu YK, Liao WC, Wu MS et al. Association Between Helicobacter pylori Eradication and Gastric Cancer Incidence: A Systematic Review and Meta-analysis. Gastroenterology. 2016;150:1113–1124.e5
- Mandel JS, Church TR, Bond JH, Ederer F, Geisser MS, Mongin SJ, et al. The effect of fecal occult-blood screening on the incidence of colorectal cancer. New Engl J Med. 2000;343(22):1603–1607.
- Marshall B.J., Warren J.R. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984;1:1311–1315. doi: 10.1016/S0140-6736(84)91816-6.
- Qaseem A, Denberg TD, Hopkins RH Jr, Humphrey LL, Levine J, Sweet DE et al. Screening for colorectal cancer: a guidance statement from the American College of Physicians. Ann Int Med. 2012;156(5):378–386.
- Rodríguez-Alonso L, Rodríguez-Moranta F, Ruiz-Cerulla A, Lobatón T, Arajol C, Binefa G et al. An urgent referral strategy for symptomatic patients with suspected colorectal cancer based on a quantitative immunochemical faecal occult blood test. Dig Liver Dis 2015;47:797–804.
- Sabatino SA, White MC, Thompson TD, Klabunde CN; Centers for Disease Control and Prevention (CDC) Cancer screening test use - United States, 2013. MMWR Morb Mortal Wkly Rep. 2015;64:464–468.
- Testoni P.A., Masci E., Marchi R., Guslandi M., Ronchi G., Tittobello A. Gastric cancer in chronic atrophic gastritis. Associated gastric ulcer adds no further risk. J. Clin. Gastroenterol. 1987;9:298–302. doi: 10.1097/00004836-198706000-00011.
- Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65:87–108.
- Uemura N., Okamoto S., Yamamoto S., Matsumura N., Yamaguchi S., Yamakido M. Et al.Helicobacter pylori infection and the development of gastric cancer. N. Engl. J. Med. 2001;345:784–789. doi: 10.1056/NEJMoa001999.
- Vannella L, Lahner E, Bordi C, Pilozzi E, Di Giulio E, Corleto VD et al. Reversal of atrophic body gastritis after H. pylori eradication at long-term follow-up. Dig Liver Dis. 2011;43:295–299.
- Von Karsa L, Patnick J, Segnan N, Atkin W, Halloran S, Lansdorp-Vogelaar I, et al. European Colorectal Cancer Screening Guidelines Working Group, European guidelines for quality assurance in colorectal cancer screening and diagnosis: overview and introduction to the full supplement publication. Endoscopy. 2013;45(1):51–59.
- Williams TGS, Cubiella J, Griffin SJ, Walter FM, Usher-Smith JA. Risk prediction models for colorectal cancer in people with symptoms: a systematic review. BMC Gastroenterol 2016;16:63.
- Zamani M, Ebrahimtabar F, Zamani V, Miller WH, Alizadeh-Navaei R, Shokri-Shirvani J et al. : Systematic review with meta-analysis: the worldwide prevalence of Helicobacter pylori infection. Aliment Pharmacol Ther. 2018;47(7):868–76. 10.1111/apt.14561
There are 20 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Research articles |
| Authors | |
| Publication Date | December 31, 2019 |
| Published in Issue | Year 2019 Volume: 5 Issue: 3 |
e-ISSN 2149-7796