Research Article
Year 2020,
Volume: 6 Issue: 3, 352 - 357, 31.12.2020
Abstract
Supporting Institution
Kırşehir Ahi Evran Üniversitesi
Project Number
TIP.A4.19.002
References
- Arguelles, S., Garcia, S., Maldonado, M., Machado, A., & Ayala, A. (2004). Do the serum oxidative stress biomarkers provide a reasonable index of the general oxidative stress status? Biochimica et Biophysica Acta, 1674(3), 251-259. doi:10.1016/j.bbagen.2004.06.023 Arsalani-Zadeh, R., Ullah, S., Khan, S., & MacFie, J. (2011). Oxidative stress in laparoscopic versus open abdominal surgery: a systematic review. Journal of Surgical Research, 169(1), e59-68. doi:10.1016/j.jss.2011.01.038
- Bellieni, C. V., Iantorno, L., Perrone, S., Rodriguez, A., Longini, M., Capitani, S., & Buonocore, G. (2009). Even routine painful procedures can be harmful for the newborn. Pain, 147(1-3), 128-131. doi:10.1016/j.pain.2009.08.025
- Bhardwaj, P., Garg, P. K., Maulik, S. K., Saraya, A., Tandon, R. K., & Acharya, S. K. (2009). A randomized controlled trial of antioxidant supplementation for pain relief in patients with chronic pancreatitis. Gastroenterology, 136(1), 149-159 e142. doi:10.1053/j.gastro.2008.09.028
- Dogru, A., Balkarli, A., Cetin, G. Y., Neselioglu, S., Erel, O., Tunc, S. E., & Sahin, M. (2016). Thiol/disulfide homeostasis in patients with ankylosing spondylitis. Bosnian Journal of Basic Medical Sciences. Udruzenje Basicnih Mediciniskih Znanosti, 16(3), 187-192. doi:10.17305/bjbms.2016.1001
- Erel, O. (2005). A new automated colorimetric method for measuring total oxidant status. Clinical Biochemistry, 38(12), 1103-1111. doi:10.1016/j.clinbiochem.2005.08.008
- Erel, O., & Neselioglu, S. (2014). A novel and automated assay for thiol/disulphide homeostasis. Clinical Biochemistry, 47(18), 326-332. doi:10.1016/j.clinbiochem.2014.09.026
- Ergonenc, T., & Beyaz, S. G. (2019). T Long-term Effects of Ultrasound-guided Genicular Nerve Pulsed Radiofrequency on Pain and Knee Functions in Patients with Gonarthrosis. . J Sakarya Tıp Dergis, 9(1), 52-58. doi:10.31832/smj.506472
- Grune, T., & Berger, M. M. (2007). Markers of oxidative stress in ICU clinical settings: present and future. Current Opinion in Clinical Nutrition and Metabolic Care, 10(6), 712-717. doi:10.1097/MCO.0b013e3282f0c97c
- Inanır, A., Sogut, E., Ayan, M., & Inanır, S. ( 2013). Evaluation of Pain Intensity and Oxidative Stress Levels in Patients with Inflammatory and Non-Inflammatory Back Pain. Eur J Gen Med., 10(4), 185-190. doi:doi.org/10.29333/ejgm/82205
- Karcioglu, O., Topacoglu, H., Dikme, O., & Dikme, O. (2018). A systematic review of the pain scales in adults: Which to use? American Journal of Emergency Medicine, 36(4), 707-714. doi:10.1016/j.ajem.2018.01.008 Kerkweg, U., Pamp, K., Fieker, J., Petrat, F., Hider, R. C., & de Groot, H. (2010). Release of redox-active iron by muscle crush trauma: no liberation into the circulation. Shock, 33(5), 513-518. doi:10.1097/SHK.0b013e3181c4f56e
- Nar, R., & Calıs, A. G. (2018). Assessment of dynamic thiol/disulfide homeostasis in patients with asthma. Journal of Laboratory Medicine, 42(3), 99. doi:https://doi.org/10.1515/labmed-2017-0144
- Nashed, M. G., Balenko, M. D., & Singh, G. (2014). Cancer-induced oxidative stress and pain. Curr Pain Headache Rep, 18(1), 384. doi:10.1007/s11916-013-0384-1
- Perrone, S., Bellieni, C. V., Negro, S., Longini, M., Santacroce, A., Tataranno, M. L., . . . Buonocore, G. (2017). Oxidative Stress as a Physiological Pain Response in Full-Term Newborns. Oxidative Medicine and Cellular Longevity, 2017, 3759287. doi:10.1155/2017/3759287
- Tuzcu, A., Baykara, R. A., Alisik, M., Omma, A., Acet, G. K., Dogan, E., . . . Erel, O. (2019). Alteration of Thiol-Disulfide Homeostasis in Fibromyalgia Syndrome. Acta Medica (Hradec Kralove), 62(1), 12-18. doi:10.14712/18059694.2019.40
- Ziskoven, C., Jager, M., Zilkens, C., Bloch, W., Brixius, K., & Krauspe, R. (2010). Oxidative stress in secondary osteoarthritis: from cartilage destruction to clinical presentation? Orthopedic Reviews, 2(2), e23. doi:10.4081/or.2010.e23
Investigation of a Possible Association Between Dynamic Thiol/Disulfide Homeostasis and Pain in Knee Arthroplasty Patients
Abstract
Objective: Dynamic thiol/disulfide homeostasis plays a pivotal role in many physiologic mechanisms. In the present study, we aimed to elucidate the relationship between postoperative pain and thiol/disulfide homeostasis in patients who underwent primary total knee arthroplasty for primary knee osteoarthritis.
Methods: This prospective uncontrolled study included 28 patients (10 male, 18 female) with a diagnosis of primary gonarthrosis who underwent primary total knee arthroplasty and met the study inclusion criteria. Venous blood samples were taken from the patients and pain values were recorded simultaneously using the visual analog scale (VAS) preoperatively and at the 4th postoperative week. Thiol/disulfide hemostasis levels were measured using a new fully-automated and spectrophotometric method developed by Erel and Neselioglu.
Results: The average age of the patients participating in the study was 66.25 ± 8.29 years and 18 (64.3%) of the patients were female. B values for preoperative native/total thiol (+7,652), preoperative disulfide/native thiol (+10,550), and postoperative total thiol (+128), positively affected the difference in VAS values. B values for preoperative disulfide (-219), postoperative disulfide (-1,297), postoperative native/total thiol (-4,238), and postoperative disulfide/native thiol (-3,316) negatively affected the difference in VAS values.
Conclusion: The disulfide level, an oxidized form in thiol/disulfide homeostasis, appears to be a valuable marker for evaluating the effect of oxidative stress on postoperative pain.
Project Number
TIP.A4.19.002
References
- Arguelles, S., Garcia, S., Maldonado, M., Machado, A., & Ayala, A. (2004). Do the serum oxidative stress biomarkers provide a reasonable index of the general oxidative stress status? Biochimica et Biophysica Acta, 1674(3), 251-259. doi:10.1016/j.bbagen.2004.06.023 Arsalani-Zadeh, R., Ullah, S., Khan, S., & MacFie, J. (2011). Oxidative stress in laparoscopic versus open abdominal surgery: a systematic review. Journal of Surgical Research, 169(1), e59-68. doi:10.1016/j.jss.2011.01.038
- Bellieni, C. V., Iantorno, L., Perrone, S., Rodriguez, A., Longini, M., Capitani, S., & Buonocore, G. (2009). Even routine painful procedures can be harmful for the newborn. Pain, 147(1-3), 128-131. doi:10.1016/j.pain.2009.08.025
- Bhardwaj, P., Garg, P. K., Maulik, S. K., Saraya, A., Tandon, R. K., & Acharya, S. K. (2009). A randomized controlled trial of antioxidant supplementation for pain relief in patients with chronic pancreatitis. Gastroenterology, 136(1), 149-159 e142. doi:10.1053/j.gastro.2008.09.028
- Dogru, A., Balkarli, A., Cetin, G. Y., Neselioglu, S., Erel, O., Tunc, S. E., & Sahin, M. (2016). Thiol/disulfide homeostasis in patients with ankylosing spondylitis. Bosnian Journal of Basic Medical Sciences. Udruzenje Basicnih Mediciniskih Znanosti, 16(3), 187-192. doi:10.17305/bjbms.2016.1001
- Erel, O. (2005). A new automated colorimetric method for measuring total oxidant status. Clinical Biochemistry, 38(12), 1103-1111. doi:10.1016/j.clinbiochem.2005.08.008
- Erel, O., & Neselioglu, S. (2014). A novel and automated assay for thiol/disulphide homeostasis. Clinical Biochemistry, 47(18), 326-332. doi:10.1016/j.clinbiochem.2014.09.026
- Ergonenc, T., & Beyaz, S. G. (2019). T Long-term Effects of Ultrasound-guided Genicular Nerve Pulsed Radiofrequency on Pain and Knee Functions in Patients with Gonarthrosis. . J Sakarya Tıp Dergis, 9(1), 52-58. doi:10.31832/smj.506472
- Grune, T., & Berger, M. M. (2007). Markers of oxidative stress in ICU clinical settings: present and future. Current Opinion in Clinical Nutrition and Metabolic Care, 10(6), 712-717. doi:10.1097/MCO.0b013e3282f0c97c
- Inanır, A., Sogut, E., Ayan, M., & Inanır, S. ( 2013). Evaluation of Pain Intensity and Oxidative Stress Levels in Patients with Inflammatory and Non-Inflammatory Back Pain. Eur J Gen Med., 10(4), 185-190. doi:doi.org/10.29333/ejgm/82205
- Karcioglu, O., Topacoglu, H., Dikme, O., & Dikme, O. (2018). A systematic review of the pain scales in adults: Which to use? American Journal of Emergency Medicine, 36(4), 707-714. doi:10.1016/j.ajem.2018.01.008 Kerkweg, U., Pamp, K., Fieker, J., Petrat, F., Hider, R. C., & de Groot, H. (2010). Release of redox-active iron by muscle crush trauma: no liberation into the circulation. Shock, 33(5), 513-518. doi:10.1097/SHK.0b013e3181c4f56e
- Nar, R., & Calıs, A. G. (2018). Assessment of dynamic thiol/disulfide homeostasis in patients with asthma. Journal of Laboratory Medicine, 42(3), 99. doi:https://doi.org/10.1515/labmed-2017-0144
- Nashed, M. G., Balenko, M. D., & Singh, G. (2014). Cancer-induced oxidative stress and pain. Curr Pain Headache Rep, 18(1), 384. doi:10.1007/s11916-013-0384-1
- Perrone, S., Bellieni, C. V., Negro, S., Longini, M., Santacroce, A., Tataranno, M. L., . . . Buonocore, G. (2017). Oxidative Stress as a Physiological Pain Response in Full-Term Newborns. Oxidative Medicine and Cellular Longevity, 2017, 3759287. doi:10.1155/2017/3759287
- Tuzcu, A., Baykara, R. A., Alisik, M., Omma, A., Acet, G. K., Dogan, E., . . . Erel, O. (2019). Alteration of Thiol-Disulfide Homeostasis in Fibromyalgia Syndrome. Acta Medica (Hradec Kralove), 62(1), 12-18. doi:10.14712/18059694.2019.40
- Ziskoven, C., Jager, M., Zilkens, C., Bloch, W., Brixius, K., & Krauspe, R. (2010). Oxidative stress in secondary osteoarthritis: from cartilage destruction to clinical presentation? Orthopedic Reviews, 2(2), e23. doi:10.4081/or.2010.e23
There are 15 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Research articles |
| Authors | |
| Project Number | TIP.A4.19.002 |
| Publication Date | December 31, 2020 |
| Published in Issue | Year 2020 Volume: 6 Issue: 3 |
e-ISSN 2149-7796