Research Article
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Year 2018, Volume: 5 Issue: 1, 110 - 115, 31.01.2018
https://doi.org/10.17546/msd.379191

Abstract

References

  • 1. Kossard S: Postmenopausal frontal fibrosing alopecia scarring alopecia in a pattern distribution.Arch Dermatol 1994;130: 770-4.
  • 2. Martínez-Pérez M. Churruca-Grijelmo M:Frontal fibrosing alopecia:an updateon epidemiology and treatment. Actas Dermosifiliograficas 2015;106:757-8.
  • 3. Esteban -Lucia L, Molina -Ruiz AM, Requena L: Update on frontal fibrosing alopecia. Actas Dermosifiliograficas 2017;108:293-304.
  • 4. Holmes SM: Frontal fibrosing alopecia: Pigmentary Disorders 2017 ; 4:257. doi:10.4172/2376-0427.1000257
  • 5. Poblet E, Jiménez F, Pascual A, et al: Frontal fibrosing alopecia versus lichen planopilaris: a clinicopathological study. Int J Dermatol 2006;45:375-80.
  • 6. Moreno-Ramirez D, Martinez FC: Frontal fibrosing alopecia: a survey in 16 patients. J Eur Acad Dermatol Venereol 2005;19:700-5.
  • 7. Tan KT, Messenger AG: Frontal fibrosing alopecia: clinical presentations and prognosis. Br J Dermatol 2009;160:75-9
  • 8. Navarro-Belmonte MR, Navarro-López V, Ramírez-Boscà A, et al: Case series of familial frontal fibrosing alopecia and a review of the literature. J Cosmet Dermatol 2015;14:64-9. doi: 10.1111/jocd.12125.
  • 9. Tziotzios C, Stefanato CM, Fenton DA,et al: Frontalfibrosing alopecia: reflections and hypotheses on aetiology and pathogenesis. ExpDermatol 2016 Nov;25:847-852. doi: 10.1111/exd.13071.
  • 10. Faulkner CF, Wilson NJ, Jones SK: Frontal fibrosing alopecia associated with cutaneous lichen planus in a premenopausal woman. Australas J Dermatol 2002; 43: 65–7.
  • 11. Samrao A, Chew AL, Price V: Frontal fibrosing alopecia: a clinical review of 36 patients. Br J Dermatol 2010;163:1296-1300.
  • 12. Ladizinski B, Bazakas A, Selim MA,et al: Frontal fibrosing alopecia: a retrospective review of 19 patients seen at Duke University. J Am Acad Dermatol 2013;68:749-55. doi: 10.1016/j.jaad.2012.09.043.
  • 13. MacDonald A, Clark C, Holmes S: Frontal fibrosing alopecia: a review of 60 cases. J Am Acad Dermatol 2012;67:955-61.
  • 14. Vano-Galvan S, Molina-Ruiz AM, Serrano-Falcon C, et al: Frontal fibrosing alopecia: a multi center review of 355 patients. J Am Acad Dermatol 2014;70:670-8.
  • 15. Banka N, Mubki T, Bunagan MJ, et al: Frontal fibrosing alopecia: A retrospective clinical review of 62 patients with treatment outcome and long-term follow-up. Int J Dermatol 2014;53: 1324-30.
  • 16. Kumbasar E, Gokdemir G, Koşlu A: Postmenopozal frontal fibrozan alopesi: olgu sunumu. Turkderm 2006; 40 (Ozel Ek B): 29-30.
  • 17. Takçı Z,Baş Y,Arıcı,A : Frontal fibrozan alopesi. J Am Acad Dermatol 2009; 61: 157-8.
  • 18. Aksoy B, Balcı M, Ustun H, Şahin S: Frontal fibrozan alopesi. Genel Tıp Derg 2011; 21: 25-8
  • 19. Özcan D, Seçkin D, GüleçT,et al. Lichen planopilaris: demographic, clinical and histopathological characteristics and treatment outcomes of 25 cases Turkderm 2015; 49: 246-252 | DOI: 10.4274/turkderm.32767
  • 20. Kossard S, Lee M-S, Wilkinson B: Postmenopausal frontal fibrosing alopecia: a frontal variant of lichen planopilaris. J Am Acad Dermatol 1997;36:59-66.
  • 21. Stockmeier M, Kunte C, Sander CA,et al: Kossard frontal fibrosing alopecia in a man. (German ) Hautarzt 2002;53:409–11.
  • 22. Ramaswamy P, Mendese G, Goldberg LJ. Scarring alopecia of the sideburns: a unique presentation of frontal fibrosing alopecia in men. Arch Dermatol 2012; 148: 1095-96
  • 23. Tosti A, Piraccini BM, Iorozzo M,et al:Frontal fibrosing alopecia in post-menopausal women. J Am Acad Dermatol 2005; 52: 55-60.
  • 24. Harries MJ, Trueb RM, Tosti A, et al: How not to get scar(r)ed: pointers to the correct diagnosis in patients with suspected primary cicatricial alopecia. Br J Dermatol 2009 ;160:482-501. doi: 10.1111/j.1365-2133.2008.09008.x
  • 25. Mirmirani P, Willey A, Headington JT,et al: Primary cicatricial alopecia: histopathologic findings do not distinguish clinical variants. J Am Acad Dermatol 2005;52:637-43.
  • 26. Rácz E, Gho C, Moorman PW, et al: Treatment of frontal fibrosing alopecia and lichen planopilaris: a systematic review. J Eur Acad Dermatol Venereol 2013; 27: 1461-70.
  • 27. Filbrandt R , Rufaut N , Jones L,et al: Primary cicatricial alopecia: diagnosis and treatment. CMAJ 2013 ;185: 1579–85.
  • 28. Georgala S, Katoulis AC, Befon A, et al: Treatment of postmenopausal frontal fibrosing alopecia with oral dutasteride. J Am Acad Dermatol 2009;61:157-8

Examination of Clinical and Demographic Characteristics of 14 Cases with Frontal Fibrosing Alopecia

Year 2018, Volume: 5 Issue: 1, 110 - 115, 31.01.2018
https://doi.org/10.17546/msd.379191

Abstract





Objective: Frontal
fibrosing alopecia (FFA) is a rare type of cicatricial alopecia seen in
postmenopausal women characterized with band-type frontal/frontotemporal hair
traction and/or significant or complete loss of the eyebrows. We aimed to
present the demographic, clinical and laboratory characteristics of female
patients diagnosed and followed-up with FFA in our clinic by comparing these
with the literature data.


Method: A
total of 14 patients who admitted to our outpatient clinic with alopecia on
the frontotemporal/frontal hairline and were clinically and/or
histopathologically diagnosed with FFA between 2011 and 2016 were evaluated
in a retrospective manner. The patients were reviewed in terms of the age of
lesion onset, localization, accompanying symptom or disease, and treatment
options.


Results: The
ages of the patients who were followed-up in our outpatient clinic with FFA
were between 52 and 73 (mean 2 years). Eight patients (57%) had total eyebrow
loss,. Laboratory tests were in normal limits or negative. Comorbidities
included thyroid disease, hypertension and coronary artery disease diabetes
mellitus. For treatment, all patients were given systemic, intralesional and
topical steroid, and topical minoxidil at various times. Four patients
received hydroxychloroquine, 2 patients acitretin, 2 patients Vitamin E, 1
patient itraconazole, and 1 patient topical tacrolimus.


Conclusion:
FFA should be considered in middle aged and elderly postmenopausal women
presenting with hair loss complaints and were detected to have frontal
hairline traction and cicatricial alopecia, and the diagnosis should be
supported by biopsy. Thereby, the disease progression may be prevented or
delayed with early diagnosis and proper treatment..


References

  • 1. Kossard S: Postmenopausal frontal fibrosing alopecia scarring alopecia in a pattern distribution.Arch Dermatol 1994;130: 770-4.
  • 2. Martínez-Pérez M. Churruca-Grijelmo M:Frontal fibrosing alopecia:an updateon epidemiology and treatment. Actas Dermosifiliograficas 2015;106:757-8.
  • 3. Esteban -Lucia L, Molina -Ruiz AM, Requena L: Update on frontal fibrosing alopecia. Actas Dermosifiliograficas 2017;108:293-304.
  • 4. Holmes SM: Frontal fibrosing alopecia: Pigmentary Disorders 2017 ; 4:257. doi:10.4172/2376-0427.1000257
  • 5. Poblet E, Jiménez F, Pascual A, et al: Frontal fibrosing alopecia versus lichen planopilaris: a clinicopathological study. Int J Dermatol 2006;45:375-80.
  • 6. Moreno-Ramirez D, Martinez FC: Frontal fibrosing alopecia: a survey in 16 patients. J Eur Acad Dermatol Venereol 2005;19:700-5.
  • 7. Tan KT, Messenger AG: Frontal fibrosing alopecia: clinical presentations and prognosis. Br J Dermatol 2009;160:75-9
  • 8. Navarro-Belmonte MR, Navarro-López V, Ramírez-Boscà A, et al: Case series of familial frontal fibrosing alopecia and a review of the literature. J Cosmet Dermatol 2015;14:64-9. doi: 10.1111/jocd.12125.
  • 9. Tziotzios C, Stefanato CM, Fenton DA,et al: Frontalfibrosing alopecia: reflections and hypotheses on aetiology and pathogenesis. ExpDermatol 2016 Nov;25:847-852. doi: 10.1111/exd.13071.
  • 10. Faulkner CF, Wilson NJ, Jones SK: Frontal fibrosing alopecia associated with cutaneous lichen planus in a premenopausal woman. Australas J Dermatol 2002; 43: 65–7.
  • 11. Samrao A, Chew AL, Price V: Frontal fibrosing alopecia: a clinical review of 36 patients. Br J Dermatol 2010;163:1296-1300.
  • 12. Ladizinski B, Bazakas A, Selim MA,et al: Frontal fibrosing alopecia: a retrospective review of 19 patients seen at Duke University. J Am Acad Dermatol 2013;68:749-55. doi: 10.1016/j.jaad.2012.09.043.
  • 13. MacDonald A, Clark C, Holmes S: Frontal fibrosing alopecia: a review of 60 cases. J Am Acad Dermatol 2012;67:955-61.
  • 14. Vano-Galvan S, Molina-Ruiz AM, Serrano-Falcon C, et al: Frontal fibrosing alopecia: a multi center review of 355 patients. J Am Acad Dermatol 2014;70:670-8.
  • 15. Banka N, Mubki T, Bunagan MJ, et al: Frontal fibrosing alopecia: A retrospective clinical review of 62 patients with treatment outcome and long-term follow-up. Int J Dermatol 2014;53: 1324-30.
  • 16. Kumbasar E, Gokdemir G, Koşlu A: Postmenopozal frontal fibrozan alopesi: olgu sunumu. Turkderm 2006; 40 (Ozel Ek B): 29-30.
  • 17. Takçı Z,Baş Y,Arıcı,A : Frontal fibrozan alopesi. J Am Acad Dermatol 2009; 61: 157-8.
  • 18. Aksoy B, Balcı M, Ustun H, Şahin S: Frontal fibrozan alopesi. Genel Tıp Derg 2011; 21: 25-8
  • 19. Özcan D, Seçkin D, GüleçT,et al. Lichen planopilaris: demographic, clinical and histopathological characteristics and treatment outcomes of 25 cases Turkderm 2015; 49: 246-252 | DOI: 10.4274/turkderm.32767
  • 20. Kossard S, Lee M-S, Wilkinson B: Postmenopausal frontal fibrosing alopecia: a frontal variant of lichen planopilaris. J Am Acad Dermatol 1997;36:59-66.
  • 21. Stockmeier M, Kunte C, Sander CA,et al: Kossard frontal fibrosing alopecia in a man. (German ) Hautarzt 2002;53:409–11.
  • 22. Ramaswamy P, Mendese G, Goldberg LJ. Scarring alopecia of the sideburns: a unique presentation of frontal fibrosing alopecia in men. Arch Dermatol 2012; 148: 1095-96
  • 23. Tosti A, Piraccini BM, Iorozzo M,et al:Frontal fibrosing alopecia in post-menopausal women. J Am Acad Dermatol 2005; 52: 55-60.
  • 24. Harries MJ, Trueb RM, Tosti A, et al: How not to get scar(r)ed: pointers to the correct diagnosis in patients with suspected primary cicatricial alopecia. Br J Dermatol 2009 ;160:482-501. doi: 10.1111/j.1365-2133.2008.09008.x
  • 25. Mirmirani P, Willey A, Headington JT,et al: Primary cicatricial alopecia: histopathologic findings do not distinguish clinical variants. J Am Acad Dermatol 2005;52:637-43.
  • 26. Rácz E, Gho C, Moorman PW, et al: Treatment of frontal fibrosing alopecia and lichen planopilaris: a systematic review. J Eur Acad Dermatol Venereol 2013; 27: 1461-70.
  • 27. Filbrandt R , Rufaut N , Jones L,et al: Primary cicatricial alopecia: diagnosis and treatment. CMAJ 2013 ;185: 1579–85.
  • 28. Georgala S, Katoulis AC, Befon A, et al: Treatment of postmenopausal frontal fibrosing alopecia with oral dutasteride. J Am Acad Dermatol 2009;61:157-8
There are 28 citations in total.

Details

Subjects Health Care Administration
Journal Section Research Article
Authors

Ayse Akbas 0000-0002-1626-1796

Fadime Kılınç

Publication Date January 31, 2018
Published in Issue Year 2018 Volume: 5 Issue: 1

Cite

APA Akbas, A., & Kılınç, F. (2018). Examination of Clinical and Demographic Characteristics of 14 Cases with Frontal Fibrosing Alopecia. Medical Science and Discovery, 5(1), 110-115. https://doi.org/10.17546/msd.379191
AMA Akbas A, Kılınç F. Examination of Clinical and Demographic Characteristics of 14 Cases with Frontal Fibrosing Alopecia. Med Sci Discov. January 2018;5(1):110-115. doi:10.17546/msd.379191
Chicago Akbas, Ayse, and Fadime Kılınç. “Examination of Clinical and Demographic Characteristics of 14 Cases With Frontal Fibrosing Alopecia”. Medical Science and Discovery 5, no. 1 (January 2018): 110-15. https://doi.org/10.17546/msd.379191.
EndNote Akbas A, Kılınç F (January 1, 2018) Examination of Clinical and Demographic Characteristics of 14 Cases with Frontal Fibrosing Alopecia. Medical Science and Discovery 5 1 110–115.
IEEE A. Akbas and F. Kılınç, “Examination of Clinical and Demographic Characteristics of 14 Cases with Frontal Fibrosing Alopecia”, Med Sci Discov, vol. 5, no. 1, pp. 110–115, 2018, doi: 10.17546/msd.379191.
ISNAD Akbas, Ayse - Kılınç, Fadime. “Examination of Clinical and Demographic Characteristics of 14 Cases With Frontal Fibrosing Alopecia”. Medical Science and Discovery 5/1 (January 2018), 110-115. https://doi.org/10.17546/msd.379191.
JAMA Akbas A, Kılınç F. Examination of Clinical and Demographic Characteristics of 14 Cases with Frontal Fibrosing Alopecia. Med Sci Discov. 2018;5:110–115.
MLA Akbas, Ayse and Fadime Kılınç. “Examination of Clinical and Demographic Characteristics of 14 Cases With Frontal Fibrosing Alopecia”. Medical Science and Discovery, vol. 5, no. 1, 2018, pp. 110-5, doi:10.17546/msd.379191.
Vancouver Akbas A, Kılınç F. Examination of Clinical and Demographic Characteristics of 14 Cases with Frontal Fibrosing Alopecia. Med Sci Discov. 2018;5(1):110-5.