Case Report
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Year 2019, Volume: 6 Issue: 3, 59 - 62, 30.03.2019
https://doi.org/10.17546/msd.500996

Abstract

References

  • 1. Wenig BM. Laryngeal mucosal malignant melanoma: a clinicopathologic,immunohistochemical, and ultrastructural study of four patients and a review of the literature. Cancer. 1995;75:1568-1577
  • 2. Cojocaru O, Aşchie M, Mocanu L, Baltatescu GI. Laryngeal primary malignant melanoma: a case report.Rom J MorpholEmbryol 2015, 56(4):1513-1516
  • 3. Amin HH, Petruzzeli GJ, Huain AN, Nickoloff BJ. Primary malignant melanoma of the larynx. Arch Pathol Lab Med,2001,125:271-273.
  • 4. El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. World Health Organization Classification of Head and Neck Tumours. 4th ed. Lyon: IARC; 2017. pp. 60–61. 126-127.
  • 5. Terada T, Saeki N, Toh K, Uwa N, Sagawa K, Mouri T, Sakagami M. Primary malignantmelanoma of the larynx:a case report and litareture review. AurisNasus Larynx, 2007, 34(1):105-110.
  • 6. Zaghi S, Pouldar D, Lai C, Chettri DK. Subglottic presentation of a rare tumor:primary or metastatic? Primary mucosal melanoma of the subglottic larynx. JAMA Otolaryngol Head Neck Surg,2013,139(7):739-740.
  • 7. Lohia S, Boersma I, Lentsch E. Primary malignant melanoma of the larynx- A case report. Otolaryngology Case Reports 4 (2017) 15-17.

A case of primary malignant melanoma of the larynx

Year 2019, Volume: 6 Issue: 3, 59 - 62, 30.03.2019
https://doi.org/10.17546/msd.500996

Abstract





Objective:
 Malignant melanoma of the larynx is an
uncommon tumor type that can be seen as a primary tumor or as a metastasis
from a cutaneous primary lesion.  Morphological appearances of this tumor are
readily confused with the other types of laryngeal cancers.  A new case of primary laryngeal malignant
melanoma has been presented in this case report .


Case:
The patient was a 54-year-old man without any clinical evidence of other
cutaneous malignant melanocytic lesions. Microscopically,
polygonal-epithelioid tumor cells containing cytoplasmic and nuclear melanin
were located under the mucosal squamous epithelial cells. Atypical mitotic
figures were also present. Ulceration and disruption of the epithelium
weren’t observed. Immunohistochemical studies were positive for S100, HMB-45,
Melan-A and vimentin while it was negative for cytokeratin. Based on findings
this diagnosis was established.


References

  • 1. Wenig BM. Laryngeal mucosal malignant melanoma: a clinicopathologic,immunohistochemical, and ultrastructural study of four patients and a review of the literature. Cancer. 1995;75:1568-1577
  • 2. Cojocaru O, Aşchie M, Mocanu L, Baltatescu GI. Laryngeal primary malignant melanoma: a case report.Rom J MorpholEmbryol 2015, 56(4):1513-1516
  • 3. Amin HH, Petruzzeli GJ, Huain AN, Nickoloff BJ. Primary malignant melanoma of the larynx. Arch Pathol Lab Med,2001,125:271-273.
  • 4. El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. World Health Organization Classification of Head and Neck Tumours. 4th ed. Lyon: IARC; 2017. pp. 60–61. 126-127.
  • 5. Terada T, Saeki N, Toh K, Uwa N, Sagawa K, Mouri T, Sakagami M. Primary malignantmelanoma of the larynx:a case report and litareture review. AurisNasus Larynx, 2007, 34(1):105-110.
  • 6. Zaghi S, Pouldar D, Lai C, Chettri DK. Subglottic presentation of a rare tumor:primary or metastatic? Primary mucosal melanoma of the subglottic larynx. JAMA Otolaryngol Head Neck Surg,2013,139(7):739-740.
  • 7. Lohia S, Boersma I, Lentsch E. Primary malignant melanoma of the larynx- A case report. Otolaryngology Case Reports 4 (2017) 15-17.
There are 7 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Reports
Authors

Özge Kaya 0000-0001-6887-0553

Dudu Solakoğlu Kahraman 0000-0002-4126-5326

Gülden Diniz 0000-0003-1512-7584

Gönül Demir This is me 0000-0002-2927-8052

Publication Date March 30, 2019
Published in Issue Year 2019 Volume: 6 Issue: 3

Cite

APA Kaya, Ö., Solakoğlu Kahraman, D., Diniz, G., Demir, G. (2019). A case of primary malignant melanoma of the larynx. Medical Science and Discovery, 6(3), 59-62. https://doi.org/10.17546/msd.500996
AMA Kaya Ö, Solakoğlu Kahraman D, Diniz G, Demir G. A case of primary malignant melanoma of the larynx. Med Sci Discov. March 2019;6(3):59-62. doi:10.17546/msd.500996
Chicago Kaya, Özge, Dudu Solakoğlu Kahraman, Gülden Diniz, and Gönül Demir. “A Case of Primary Malignant Melanoma of the Larynx”. Medical Science and Discovery 6, no. 3 (March 2019): 59-62. https://doi.org/10.17546/msd.500996.
EndNote Kaya Ö, Solakoğlu Kahraman D, Diniz G, Demir G (March 1, 2019) A case of primary malignant melanoma of the larynx. Medical Science and Discovery 6 3 59–62.
IEEE Ö. Kaya, D. Solakoğlu Kahraman, G. Diniz, and G. Demir, “A case of primary malignant melanoma of the larynx”, Med Sci Discov, vol. 6, no. 3, pp. 59–62, 2019, doi: 10.17546/msd.500996.
ISNAD Kaya, Özge et al. “A Case of Primary Malignant Melanoma of the Larynx”. Medical Science and Discovery 6/3 (March 2019), 59-62. https://doi.org/10.17546/msd.500996.
JAMA Kaya Ö, Solakoğlu Kahraman D, Diniz G, Demir G. A case of primary malignant melanoma of the larynx. Med Sci Discov. 2019;6:59–62.
MLA Kaya, Özge et al. “A Case of Primary Malignant Melanoma of the Larynx”. Medical Science and Discovery, vol. 6, no. 3, 2019, pp. 59-62, doi:10.17546/msd.500996.
Vancouver Kaya Ö, Solakoğlu Kahraman D, Diniz G, Demir G. A case of primary malignant melanoma of the larynx. Med Sci Discov. 2019;6(3):59-62.