Case Report
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ACUTE FACIAL PARALYSIS DUE TO EBV INFECTION

Year 2020, Volume: 8 Issue: 1, 79 - 83, 20.04.2020
https://doi.org/10.37696/nkmj.569544

Abstract

Ebstein Barr virus (EBV) is a member
of Herpes-viridae. Altough elevations of liver enzymes and upper respiratory tract infection
findings is commonly seen during the EBV infection, acute facial paralysis is
rare complication. Here, we report acute facial paralysis associated with EBV
infection in an eight years old girl. With symptomatic treatment, the patient
recovered without cure with corticosteroids and antiviral therapy and no
complications developed.
Physicians
should keep in mind that neurological complications, such as facial paralysis, other
than upper respiratory tract infections, may develop during infectious
mononucleosis due to EBV and that patients should be followed closely.

References

  • Gershon AA, Hotez PJ, Katz SL. Epstein-Barr virus infections. Krugman's infectious diseases of children. 11th. edit. London: Mosby, 2003: 98-115.
  • Fidan I, Yüksel S, İmir T. Değişik yaş gruplarında Epstein-Barr virus antikorlarının araştırılması. J Infect 2005; 19: 453-456.
  • Vouloumanou EK, Rafailidis PI, Falagas ME. Current diagnosis and management of infectious mononucleosis. Curr opin Hematol 2012; 19: 14-20
  • Coddington CT, Isaacs JD, Siddiqui AQ, Andrews TC. Neurological picture. Bilateral facial nerve palsy associated with Epstein-Barr virus infection. JNeurol Neurosurg Psychiatr. 2010; 81: 1155–1156.
  • Diedler J, Rieger S, Koch A, Parthe-Peterhans S, Schwaninger M. Bilateral facial palsy: Epstein-Barr virus, not Lyme disease. Eur JNeurol. 2006; 13: 1029–1030.Ha¨usler M, Ramaekers VT, Doenges M, et al. Neurological complications of acute and persistent Epstein–Barr virus infection in paediatric patients. J Med Virol 2002;68: 253–63.
  • Lennon P, Saunders J, Fenton JE. A longer stay for fort he kissing disease: epidemiology of bacterial tonsillitis and infectious mononucleosis over a 20 year period. J Laryngol Otol 2013; 7: 1-5.
  • González Saldaña N, Monroy Colín VA, Piña Ruiz G, Juárez Olguín H. Clinical and laboratory characteristics of infectious mononucleosis by Epstein-Barr virus in Mexican children. BMC Res Notes. 2012; 6: 361.
  • Medović R, Igrutinović Z, Radojević-Marjanović R, Marković S, Rasković Z, Simović A, Tanasković-Nestorović J, Radovanović M, VuIetić B. Clinical and laboratory differences between Epstein-Barr and cytomegalovirus infectious mononucleosis in children. Srp Arh Celok Lek. 2016; 1-2: 56-62.
  • 10.Chan CW, Chiang AK, Chan KH, Lau AS. Ebstein-Barr virus associated infectious mononucleosis in Chinese children. Pediatr Infect Dis J 2003; 22: 974-978.Sumaya CV, Ench Y. Epstein-Barr virus infectious mononucleosis in children. Pediatrics 1985; 75: 1003-10.
  • Yanagihara N, Hinohira Y, Honda N. Pathogenesis of facial nerve paralysis associated with infectious mononucleosis: rationale based on a review of 2 cases. Facial N Res Jpn 2000; 20:61-63.
  • Stahl N, Ferit T. Recurrent bilateral peripheral facial palsy J Laryngol Otol 1989; 103: 117-119.
  • Terada K, Niizuma T, Kosaka Y, Inoue M, Ogita S, Kataoka N. Bilateral facial nerve palsy associated with Epstein-Barr virus infection with a review of the literature. Scand J Infect Dis. 2004; 36(1): 75-77.
  • De Paschale M, Clerici P. Serological diagnosis of Epstein-Barr virus infection: Problems and solutions. World JVirol. 2012; 1: 31–43.
  • Luderer R, Kok M, Niesters HGM, Schuurman R, deWeerdt O, Thijsen SFT. Real-time Epstein-Barr virus PCR for the diagnosis of primary EBV infections and EBV reactivation.MolDiagn. 2005; 9: 195–200.
  • Yabuki S, Kazahaya Y, Kubonishi I. Epstein-Barr virus antibodies in neurological diseases. FoliaPsychiatrNeurol Jpn. 1985; 39: 85–93.
  • Cengiz AB, Cultu Kantaroğlu O, Secmeer G, Ceyhan M, Kara A, Gurgey A. Infectious mononucleosis in Turkish children. Turk J Pediatr 2010; 52: 245-254.
  • Wilson C, Grant CC. Picture of the month. Facial nevre palsy secondary to Epstein-Barr virus infection. Arch Pediatr Adolesc Med. 1997; 151: 739–740.
  • Grose C, Henle W, Henle G, Feorino PM. Primary Epstein–Barr-Virus Infections in Acute Neurologic Diseases. NEnglJMed. 1975; 292: 392–395.
  • Andersson J, SternerG. A 16-month-old boy with infectious mononucleosis, parotitis and Bell’s palsy. Acta Paediatr Scand. 1985; 74: 629–632.
  • Vogelnik K, Matos A. Facial nerve palsy secondary to Epstein-Barr virus infection of the middle ear in pediatric population may be more common than we think. Wien Klin Wochenschr. 2017; 9: 18.

EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU

Year 2020, Volume: 8 Issue: 1, 79 - 83, 20.04.2020
https://doi.org/10.37696/nkmj.569544

Abstract

Ebstein Barr virüs (EBV)
Herpes-viridae ailesinin bir üyesidir. EBV enfeksiyonu seyrinde üst solunum
yolu enfeksiyonu bulguları ile birlikte asemptomatik karaciğer enzimlerinde
yükselme sıklıkla izlenmekle birlikte akut fasiyal paralizi oldukça nadir
görülmektedir. Burada sekiz yaşında EBV enfeksiyonuna bağlı akut fasiyal
paralizi olgusu sunulmuştur. Semptomatik tedavi ile birlikte hasta
kortikosteroid ve antiviral tedavi ile sekelsiz iyileşmiş ve herhangi bir
komplikasyon gelişmemiştir. Hekimler EBV’ye bağlı gelişen enfeksiyöz
mononükleoz seyri sırasında üst solunum yolu enfeksiyonları dışında fasiyal
paralizi gibi nörolojik komplikasyonların da gelişebileceğini ve hastaların
yakından takip edilmesi gerektiğini akılda bulundurmalıdır.

References

  • Gershon AA, Hotez PJ, Katz SL. Epstein-Barr virus infections. Krugman's infectious diseases of children. 11th. edit. London: Mosby, 2003: 98-115.
  • Fidan I, Yüksel S, İmir T. Değişik yaş gruplarında Epstein-Barr virus antikorlarının araştırılması. J Infect 2005; 19: 453-456.
  • Vouloumanou EK, Rafailidis PI, Falagas ME. Current diagnosis and management of infectious mononucleosis. Curr opin Hematol 2012; 19: 14-20
  • Coddington CT, Isaacs JD, Siddiqui AQ, Andrews TC. Neurological picture. Bilateral facial nerve palsy associated with Epstein-Barr virus infection. JNeurol Neurosurg Psychiatr. 2010; 81: 1155–1156.
  • Diedler J, Rieger S, Koch A, Parthe-Peterhans S, Schwaninger M. Bilateral facial palsy: Epstein-Barr virus, not Lyme disease. Eur JNeurol. 2006; 13: 1029–1030.Ha¨usler M, Ramaekers VT, Doenges M, et al. Neurological complications of acute and persistent Epstein–Barr virus infection in paediatric patients. J Med Virol 2002;68: 253–63.
  • Lennon P, Saunders J, Fenton JE. A longer stay for fort he kissing disease: epidemiology of bacterial tonsillitis and infectious mononucleosis over a 20 year period. J Laryngol Otol 2013; 7: 1-5.
  • González Saldaña N, Monroy Colín VA, Piña Ruiz G, Juárez Olguín H. Clinical and laboratory characteristics of infectious mononucleosis by Epstein-Barr virus in Mexican children. BMC Res Notes. 2012; 6: 361.
  • Medović R, Igrutinović Z, Radojević-Marjanović R, Marković S, Rasković Z, Simović A, Tanasković-Nestorović J, Radovanović M, VuIetić B. Clinical and laboratory differences between Epstein-Barr and cytomegalovirus infectious mononucleosis in children. Srp Arh Celok Lek. 2016; 1-2: 56-62.
  • 10.Chan CW, Chiang AK, Chan KH, Lau AS. Ebstein-Barr virus associated infectious mononucleosis in Chinese children. Pediatr Infect Dis J 2003; 22: 974-978.Sumaya CV, Ench Y. Epstein-Barr virus infectious mononucleosis in children. Pediatrics 1985; 75: 1003-10.
  • Yanagihara N, Hinohira Y, Honda N. Pathogenesis of facial nerve paralysis associated with infectious mononucleosis: rationale based on a review of 2 cases. Facial N Res Jpn 2000; 20:61-63.
  • Stahl N, Ferit T. Recurrent bilateral peripheral facial palsy J Laryngol Otol 1989; 103: 117-119.
  • Terada K, Niizuma T, Kosaka Y, Inoue M, Ogita S, Kataoka N. Bilateral facial nerve palsy associated with Epstein-Barr virus infection with a review of the literature. Scand J Infect Dis. 2004; 36(1): 75-77.
  • De Paschale M, Clerici P. Serological diagnosis of Epstein-Barr virus infection: Problems and solutions. World JVirol. 2012; 1: 31–43.
  • Luderer R, Kok M, Niesters HGM, Schuurman R, deWeerdt O, Thijsen SFT. Real-time Epstein-Barr virus PCR for the diagnosis of primary EBV infections and EBV reactivation.MolDiagn. 2005; 9: 195–200.
  • Yabuki S, Kazahaya Y, Kubonishi I. Epstein-Barr virus antibodies in neurological diseases. FoliaPsychiatrNeurol Jpn. 1985; 39: 85–93.
  • Cengiz AB, Cultu Kantaroğlu O, Secmeer G, Ceyhan M, Kara A, Gurgey A. Infectious mononucleosis in Turkish children. Turk J Pediatr 2010; 52: 245-254.
  • Wilson C, Grant CC. Picture of the month. Facial nevre palsy secondary to Epstein-Barr virus infection. Arch Pediatr Adolesc Med. 1997; 151: 739–740.
  • Grose C, Henle W, Henle G, Feorino PM. Primary Epstein–Barr-Virus Infections in Acute Neurologic Diseases. NEnglJMed. 1975; 292: 392–395.
  • Andersson J, SternerG. A 16-month-old boy with infectious mononucleosis, parotitis and Bell’s palsy. Acta Paediatr Scand. 1985; 74: 629–632.
  • Vogelnik K, Matos A. Facial nerve palsy secondary to Epstein-Barr virus infection of the middle ear in pediatric population may be more common than we think. Wien Klin Wochenschr. 2017; 9: 18.
There are 20 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Case Report
Authors

Hülya Baykız This is me

Ayşin Nalbantoğlu This is me 0000-0002-5757-4051

Burçin Nalbantoğlu

Nedim Samancı This is me

Şule Güler Kaçmaz

Publication Date April 20, 2020
Published in Issue Year 2020 Volume: 8 Issue: 1

Cite

APA Baykız, H., Nalbantoğlu, A., Nalbantoğlu, B., Samancı, N., et al. (2020). EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU. Namık Kemal Tıp Dergisi, 8(1), 79-83. https://doi.org/10.37696/nkmj.569544
AMA Baykız H, Nalbantoğlu A, Nalbantoğlu B, Samancı N, Kaçmaz ŞG. EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU. NKMJ. April 2020;8(1):79-83. doi:10.37696/nkmj.569544
Chicago Baykız, Hülya, Ayşin Nalbantoğlu, Burçin Nalbantoğlu, Nedim Samancı, and Şule Güler Kaçmaz. “EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU”. Namık Kemal Tıp Dergisi 8, no. 1 (April 2020): 79-83. https://doi.org/10.37696/nkmj.569544.
EndNote Baykız H, Nalbantoğlu A, Nalbantoğlu B, Samancı N, Kaçmaz ŞG (April 1, 2020) EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU. Namık Kemal Tıp Dergisi 8 1 79–83.
IEEE H. Baykız, A. Nalbantoğlu, B. Nalbantoğlu, N. Samancı, and Ş. G. Kaçmaz, “EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU”, NKMJ, vol. 8, no. 1, pp. 79–83, 2020, doi: 10.37696/nkmj.569544.
ISNAD Baykız, Hülya et al. “EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU”. Namık Kemal Tıp Dergisi 8/1 (April 2020), 79-83. https://doi.org/10.37696/nkmj.569544.
JAMA Baykız H, Nalbantoğlu A, Nalbantoğlu B, Samancı N, Kaçmaz ŞG. EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU. NKMJ. 2020;8:79–83.
MLA Baykız, Hülya et al. “EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU”. Namık Kemal Tıp Dergisi, vol. 8, no. 1, 2020, pp. 79-83, doi:10.37696/nkmj.569544.
Vancouver Baykız H, Nalbantoğlu A, Nalbantoğlu B, Samancı N, Kaçmaz ŞG. EBV ENFEKSİYONUNA BAĞLI GELİŞEN AKUT FASİYAL PARALİZİ OLGUSU. NKMJ. 2020;8(1):79-83.