Abstract
References
- Çevik MA, Yılmaz GR, Erdinç FŞ, Üçler S, Tülek N. Mortality related factors in neurology intensive care unit and the relationship of nosocomial infection and mortality. Journal of Intensive Care 2001; 1: 47-55.
- Widmer AF.Infection control and prevention strategies in the ICU. Intensivecaremed.1994; 20 (4): S7-11.
- Erturk A, Copur Cicek A, Koksal E, Şenturk Koksal Z, Ozyurt S. Microorganisms, and antibiotic susceptibilities isolated from various clinical samples of patients hospitalized in the intensive care unit. ankemderg .2012; 26 (1): 1-9.
- Yalin AN.An overview of antibiotic use and resistance in the intensive care unit. ankemderg. 2009; 23 (2) 136-42.
- de Oliveira AC, Kovner CT, da Silva RS. Nosocomial infection in an intensive care unit in a Brazilian university hospital. RevLatAmEnfermage .2010; 18 (2): 233-9.
- Rosenthal VD, Maki DG, Graves N. The International Nosocomial Infection Control Am J Infect Control 2008; 36: 1-12
- Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR.Guideline for Prevention of Surgical Site Infection 1999.Centers for Disease and Prevention, (CDC). Hospital Infection Control Practices Advisory Committee. Am J Infect Control 1999; 27 (1): 97-132. Westendorp et al.: Post-stroke infection: A systematic review and meta-analysis. BMC Neurology 2011 11: 110.
- Yılmaz N, Kose Ş, Ağuş N, Ece G, Akkoclu G, Kıraklı C. Microorganisms growing in the blood cultures of patients in the intensive care unit, antibiotic susceptibilities [Sic] and nosocomial bacteremia agents. ankemderg .2010; 24 (1): 12-9.
- Şahin AR, Yıldız BT, Aktemur A, Topal B, Nazik S, Ateş A. Evaluation of infections developing in a neurology intensive care unit of a university hospital. J Contemp Med 2019; 9 (1): 43-47.
- Eren F, Öngün G, Ural O, Öztürk Ş. One-Year Hospital Infection Rates in Neurology Intensive Care Unit: Pathogenic and Clinical Evaluation.Turk J Neurol 2017; 23: 205-210
- Yasser B. Abulhasan, Susan P. Rachel, Marc-Olivier Châtillon-Angle, Najayeb Alabdulraheem, Ian Schiller, Nandini Dendukuri, Mark R. Angle, Charles Frenette. Healthcare-associated infections in the neurological intensive care unit: Results of a 6-year surveillance study at a majortertiary care center. American Journal of Infection Control, 46 (6), 656–662.
- Ovbiagele B, Hills NK, Saver JL, Johnston SC: Frequency and determinants of pneumonia and urinary tract infection during stroke hospitalization. J Stroke Cerebrovasc Dis 2006, 15: 209-213.
- Ray U, Ramasubban S, Chakravarty C, Goswami L, Dutta S. A prospective study of ventilator-associated tracheobronchitis: incidence and etiology in intensive care unit of a tertiary care hospital. Lung India: official organ of Indian Chest Society.2017; 34 (3): 236
- Spencer RC. Epidemiology of infection in ICU's. Intensive Care Med 1994; 20 (4): 2-6.
- Mednick AS, Mayer SA.Critical care management of neurologic catastrophes. Adv Neurol 2002; 90: 87-101.2. Thenayan EA, Bolton C, Jichici D, Savard M, Teitelbaum J, Young B, et al. Neuro critical care in Canada: evolving streams in a new discipline.Can J Neurol Sci 2008; 35: 405-8
- Ropper AH.Neurological intensive care to. Ann Neurol 1992; 32: 564-9.
- Inanc, Y., Gokce, M., Tuncel, D., Inanc, Y., Ozcekic Demirhan, S., Bavli, S. Percutaneous Endoscopic gastrostomy in neurology intensive and care unit. IJSM 2018; 4 (1), 33-5.
- Graves N Harbarth S, Beyersmann J, Barnett A, Halton K, Cooper B, Estimating the Cost of Health Care-Associated Infections: Mind Your p's and q's, Clinical Infectious Diseases, 2010, 50, (7), 1017–1021
- Craig A. Umscheid, Matthew D. Mitchell, Jalpa A. Doshi, R. Agarwal, K. Williams, PJ Brennan Estimating the proportion of healthcare-associated infections that are reasonably preventable and the related mortality and costs. Infect Control Hosp Epidemiol, 2011 32 (2),101-114.
- Çıragil P. Antimicrobial Resistance in Intensive Care Units in Turkey Problem.Turkish Microbiology Cem Derg 2016 46 (3): 97-104.
- Warren JW.Catheter associated urinary tract infections. Int J Antimicrob Agents 2001; 17: 299-303.
The Relationship Between Mortality and Hospital-Acquired Infections in Patients Followed-up with Neurological Complaints in the Third Level Intensive Care Unit
Abstract
Aim: We aimed to evaluate the demographic characteristics of patients with neurological complaints in Level III Intensive Care Unit (ICU) and hospital-acquired infection rate, isolated pathogen factors and regional distribution of them, relationship with invasive device use, and mortality rates.
Material and Methods: 176 patients who were followed up in ICU within 12 months were included in the study. The demographic information, analysis, culture results of the patients, consultation notes of the infection committee doctors, and nurse observation charts were examined and the data of the patients were collected.
Results: 46 of the 176 patients was died included in the present study died. The mortality rate was determined 26.13%. A total of 38 hospital-acquired infections (HAI) attacks were detected in 33 of all patients due to some of the patients have more than one attack. In addition, the rate of HAI was found as 21.59%. Central venous catheter-related bloodstream infections (CRBSI) in 2 patients (6.06%), mechanical ventilator independent pneumonia in 6 patients (18.1%), mechanical ventilator-associated pneumonia (VAP) or ventilator-associated tracheobronchitis (VAT) was detected in 11 patients (33.3%) and urinary tract infection (UTI) was found in 14 patients (42.4%). The most common hospital-acquired pneumonia (HAP) was urinary tract infection (UTI). It was observed that Acinetobacter baumannii was detected as the most common cause of pneumonia, and Escherichia coli was detected as the most common cause of urinary tract infection. Whereas, the mortality rate was found as 60.60% (20 of 33) in patients with HAI attack, this ratio was found as 18.18% (26 of 143) in patients without HAI attack.
Conclusion: In patients who followed up with neurological complaints in the ICU, it was determined that having a HAI, recurrent HAI attacks, and ventilator associated pneumonia (VAP) or ventilator associated tracheobronchitis (VAT) increased mortality. Every physician who follows a patient in the ICU should evaluate the pathogen factors and infection rates in patients in his / her unit, and compare them with national and international data. By knowing infection surveillance data in ICUs, effective empirical treatment can be provided until the exact HAI pathogen is known. Knowing and effectively treating HAI data in ICU affects the prognosis, cost, and mortality rate of primary neurological disease by lowering HAI rates.
References
- Çevik MA, Yılmaz GR, Erdinç FŞ, Üçler S, Tülek N. Mortality related factors in neurology intensive care unit and the relationship of nosocomial infection and mortality. Journal of Intensive Care 2001; 1: 47-55.
- Widmer AF.Infection control and prevention strategies in the ICU. Intensivecaremed.1994; 20 (4): S7-11.
- Erturk A, Copur Cicek A, Koksal E, Şenturk Koksal Z, Ozyurt S. Microorganisms, and antibiotic susceptibilities isolated from various clinical samples of patients hospitalized in the intensive care unit. ankemderg .2012; 26 (1): 1-9.
- Yalin AN.An overview of antibiotic use and resistance in the intensive care unit. ankemderg. 2009; 23 (2) 136-42.
- de Oliveira AC, Kovner CT, da Silva RS. Nosocomial infection in an intensive care unit in a Brazilian university hospital. RevLatAmEnfermage .2010; 18 (2): 233-9.
- Rosenthal VD, Maki DG, Graves N. The International Nosocomial Infection Control Am J Infect Control 2008; 36: 1-12
- Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR.Guideline for Prevention of Surgical Site Infection 1999.Centers for Disease and Prevention, (CDC). Hospital Infection Control Practices Advisory Committee. Am J Infect Control 1999; 27 (1): 97-132. Westendorp et al.: Post-stroke infection: A systematic review and meta-analysis. BMC Neurology 2011 11: 110.
- Yılmaz N, Kose Ş, Ağuş N, Ece G, Akkoclu G, Kıraklı C. Microorganisms growing in the blood cultures of patients in the intensive care unit, antibiotic susceptibilities [Sic] and nosocomial bacteremia agents. ankemderg .2010; 24 (1): 12-9.
- Şahin AR, Yıldız BT, Aktemur A, Topal B, Nazik S, Ateş A. Evaluation of infections developing in a neurology intensive care unit of a university hospital. J Contemp Med 2019; 9 (1): 43-47.
- Eren F, Öngün G, Ural O, Öztürk Ş. One-Year Hospital Infection Rates in Neurology Intensive Care Unit: Pathogenic and Clinical Evaluation.Turk J Neurol 2017; 23: 205-210
- Yasser B. Abulhasan, Susan P. Rachel, Marc-Olivier Châtillon-Angle, Najayeb Alabdulraheem, Ian Schiller, Nandini Dendukuri, Mark R. Angle, Charles Frenette. Healthcare-associated infections in the neurological intensive care unit: Results of a 6-year surveillance study at a majortertiary care center. American Journal of Infection Control, 46 (6), 656–662.
- Ovbiagele B, Hills NK, Saver JL, Johnston SC: Frequency and determinants of pneumonia and urinary tract infection during stroke hospitalization. J Stroke Cerebrovasc Dis 2006, 15: 209-213.
- Ray U, Ramasubban S, Chakravarty C, Goswami L, Dutta S. A prospective study of ventilator-associated tracheobronchitis: incidence and etiology in intensive care unit of a tertiary care hospital. Lung India: official organ of Indian Chest Society.2017; 34 (3): 236
- Spencer RC. Epidemiology of infection in ICU's. Intensive Care Med 1994; 20 (4): 2-6.
- Mednick AS, Mayer SA.Critical care management of neurologic catastrophes. Adv Neurol 2002; 90: 87-101.2. Thenayan EA, Bolton C, Jichici D, Savard M, Teitelbaum J, Young B, et al. Neuro critical care in Canada: evolving streams in a new discipline.Can J Neurol Sci 2008; 35: 405-8
- Ropper AH.Neurological intensive care to. Ann Neurol 1992; 32: 564-9.
- Inanc, Y., Gokce, M., Tuncel, D., Inanc, Y., Ozcekic Demirhan, S., Bavli, S. Percutaneous Endoscopic gastrostomy in neurology intensive and care unit. IJSM 2018; 4 (1), 33-5.
- Graves N Harbarth S, Beyersmann J, Barnett A, Halton K, Cooper B, Estimating the Cost of Health Care-Associated Infections: Mind Your p's and q's, Clinical Infectious Diseases, 2010, 50, (7), 1017–1021
- Craig A. Umscheid, Matthew D. Mitchell, Jalpa A. Doshi, R. Agarwal, K. Williams, PJ Brennan Estimating the proportion of healthcare-associated infections that are reasonably preventable and the related mortality and costs. Infect Control Hosp Epidemiol, 2011 32 (2),101-114.
- Çıragil P. Antimicrobial Resistance in Intensive Care Units in Turkey Problem.Turkish Microbiology Cem Derg 2016 46 (3): 97-104.
- Warren JW.Catheter associated urinary tract infections. Int J Antimicrob Agents 2001; 17: 299-303.
Details
| Primary Language | English |
|---|---|
| Subjects | Clinical Sciences, Infectious Diseases |
| Journal Section | Research Articles |
| Authors | |
| Publication Date | January 25, 2021 |
| Submission Date | November 28, 2020 |
| Published in Issue | Year 2021 Volume: 2 Issue: 1 |
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