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Antibiotic Susceptibilities of Group B Streptococci

Year 2011, Volume: 28 Issue: 1, 1 - 3, 15.02.2012

Aziz Dilek Hasan Kesbiç Nursel Dilek

Abstract

Streptococcus agalactiae is a frequent cause of serious infections in newborn babies. It has increasingly been recognized as a pathogen in nonpregnant adults. Penicillin and ampicillin are the drugs of choice for treatment of group B streptococcus (GBS) infections. Widespread use of these antibiotics has potentated the emergence of antibiotic resistance. Total 56 isolates included in the study were recovered from vaginal swabs and ürine samples. Isolates were tested for antimicrobial susceptibility by Kirby-Bauer disk diffusion susceptibility testing method. All of the 56 clinical isolates tested were fully susceptible to penicillin, ampicillin and cephalothin. Only 8 (14.2%) and 6 (10.7%) were resistant to erythromycin and clindamycin, respectively. All of the 56 clinical isolates were not susceptible to tetracycline.

Keywords

Streptococcus agalactiae group B streptococcus penicilin erythromycin tetracycline ciprofloxacin

References

  • Al-Sweih, N., Jamal, M., Kurdia, M., Abduljabar, R., Rotimi, V. 2005. Antibiotic susceptibility profile of group B streptococcus (streptococ- cusagalactiae ) at the Maternity Hospital, Kuwait. Med. Princ. Pract.14, 260–263.
  • Betriu, C., Culebras, E., Gomez, M., Rodríguez-Avial, I., Sanchez, B.A., Agreda, M.C., Picazo, J.J. 2003. Erythromycin and clindamycin resistance and telithromycin susceptibility in streptococcus agalactiae. Antimicrob. Agents Ch. 47, 1112–1114.
  • De Mouy, D., Cavallo, J.D., Leclercq, R., Fabre, R. The Aforcopı-Bıo Network. 2001. Antibiotic susceptibility and mechanisms of erythromycin resistance in clinical ısolates of streptococcus agalactiae: french multicenter study. Antimicrob. Agents Ch. 45, 2400–2402.
  • Elbaradie, S.M.Y., Mahmoud, M., Farid, M. 2009. Maternal and neonatal screening for group B streptococci by SCPB gene based PCR: a pre liminary study. Indian J. Med. Microbi. 27, 17-21.
  • Figueira-Coelho, J., Ramirez, M., Salgado, M.J., Melo-Cristino, J. 2004. Streptococcus agalactiae in a large portuguese teaching hospital: anti- microbial susceptibility, serotype distribution, and clonal analysis of macrolide-resistant ısolates. Microb. Drug Resist. 10, 31-36.
  • Fluegge, K., Supper, S., Siedler, A., Berner, R. 2004. Antibiotic susceptibility in neonatal invasive isolates of streptococcus agalactiae in a 2-year nationwide surveillance study in Germany. Antimicrob. Agents Ch. 48, 4444–4446.
  • Karakus, M., Karaca, D.Y., Günçiner, Ş. 2007. Colonization and antimicrobial resistance patern of group B streptococcus in pregnant women. Ege J. Med. 46, 151 -154.
  • Kawamura, Y., Fujiwara, H., Mishima, N., Tanaka, Y., Tanimoto, A., Ikawa, S., Itoh Y., Ezaki, T. 2003. First streptococcus agalactiae isolates highly resistant to quinolones, with point mutations in gyrA and parC. Antimicrob. Agents Ch. 47, 3605-3609
  • Kraśnianin, E., Skret-Magierło, J., Witalis, J., Barnaś, E., Kluz, T., Kozieł, A., Skret, A. 2009. The incidence of streptococcus group b in 100 parturient women and the transmission of pathogens to the newborn. Ginekol. Pol. 80, 285-289.
  • Kulkarni, A.A., Pawar, S.G., Dharmadhikari, C.A., Kulkarni, R.D. 2001. Colonization of pregnant women and their newborn infants with group-B streptococci. Indian J. Med. Microbi. 19, 1-4.
  • Money, D.M., Dobson, S. 2004. The prevention of early-onset neonatal group B streptococcal disease. J. Obstet. Gynaecol. Can. 26, 826–832.
  • Monique, T.S., Jan, K., Louis, K., Bakkers, J., Melchers, W., Spanjaard, L., Wannet, W.J., Hoogkamp-Korstanje, M.A. 2006. Serotypes, geno types and antibiotic susceptibility profiles of group B streptococci causing neonatal sepsis and meningitisbefore and after introduction of antibiotic prophylaxis. Pediatr. Infect. Dis. J. 25, 945-948.
  • Moyo, S.R., Maeland, J.A., Bergh, K. 2002. Typing of human isolates of streptococcus agalactiae (group B streptococcus, gbs) strains from Zimbabwe. J. Med. Microbiol. 51, 595–600.
  • Ölçü, M., Eşel, D. 2007. Antibiotic susceptibilities of clinical streptococcus agalactiae isolates. J. Health Sci. 16, 23-27. 3 Dilek et al.
  • Schrag, S.J., Phil, D., Zywicki, S. Farley, M.M., Reingold, A.L., Harrison, L.H., Lefkowitz, L.B., Hadler, J.L., Danila, R., Cieslak, P.R., Schuchat, A. 2000. Group B streptococcal disease in the era of intrapartum antibiotic prophylaxis. N. Engl. J. Med. 342, 15-20.
  • Topkaya, A., Küçükercan, M., Oğuzoğlu, N., Ünal, N., Narin, K. 2003. Antibiotic susceptibilities of group B streptococci isolated from vaginal and rectal colonization in pregnant women. J. Turk. Microbi. Society. 33, 242-245.
  • Tünger, A., Çavuşoğlu, C., Korkmaz, M. 2005. Group B streptococcus. Asya Microbi. 94-96.
  • Quiroga, M., Pegels, E., Oviedo, P., Pereyra, E., Vergara, M. 2008. Antibiotic susceptibility patterns and prevalence of group B streptococcus isolated from pregnant women in misiones, Argentina. Brazilian J. Microbi. 39, 245-25.

Year 2011, Volume: 28 Issue: 1, 1 - 3, 15.02.2012

Aziz Dilek Hasan Kesbiç Nursel Dilek

Abstract

References

  • Al-Sweih, N., Jamal, M., Kurdia, M., Abduljabar, R., Rotimi, V. 2005. Antibiotic susceptibility profile of group B streptococcus (streptococ- cusagalactiae ) at the Maternity Hospital, Kuwait. Med. Princ. Pract.14, 260–263.
  • Betriu, C., Culebras, E., Gomez, M., Rodríguez-Avial, I., Sanchez, B.A., Agreda, M.C., Picazo, J.J. 2003. Erythromycin and clindamycin resistance and telithromycin susceptibility in streptococcus agalactiae. Antimicrob. Agents Ch. 47, 1112–1114.
  • De Mouy, D., Cavallo, J.D., Leclercq, R., Fabre, R. The Aforcopı-Bıo Network. 2001. Antibiotic susceptibility and mechanisms of erythromycin resistance in clinical ısolates of streptococcus agalactiae: french multicenter study. Antimicrob. Agents Ch. 45, 2400–2402.
  • Elbaradie, S.M.Y., Mahmoud, M., Farid, M. 2009. Maternal and neonatal screening for group B streptococci by SCPB gene based PCR: a pre liminary study. Indian J. Med. Microbi. 27, 17-21.
  • Figueira-Coelho, J., Ramirez, M., Salgado, M.J., Melo-Cristino, J. 2004. Streptococcus agalactiae in a large portuguese teaching hospital: anti- microbial susceptibility, serotype distribution, and clonal analysis of macrolide-resistant ısolates. Microb. Drug Resist. 10, 31-36.
  • Fluegge, K., Supper, S., Siedler, A., Berner, R. 2004. Antibiotic susceptibility in neonatal invasive isolates of streptococcus agalactiae in a 2-year nationwide surveillance study in Germany. Antimicrob. Agents Ch. 48, 4444–4446.
  • Karakus, M., Karaca, D.Y., Günçiner, Ş. 2007. Colonization and antimicrobial resistance patern of group B streptococcus in pregnant women. Ege J. Med. 46, 151 -154.
  • Kawamura, Y., Fujiwara, H., Mishima, N., Tanaka, Y., Tanimoto, A., Ikawa, S., Itoh Y., Ezaki, T. 2003. First streptococcus agalactiae isolates highly resistant to quinolones, with point mutations in gyrA and parC. Antimicrob. Agents Ch. 47, 3605-3609
  • Kraśnianin, E., Skret-Magierło, J., Witalis, J., Barnaś, E., Kluz, T., Kozieł, A., Skret, A. 2009. The incidence of streptococcus group b in 100 parturient women and the transmission of pathogens to the newborn. Ginekol. Pol. 80, 285-289.
  • Kulkarni, A.A., Pawar, S.G., Dharmadhikari, C.A., Kulkarni, R.D. 2001. Colonization of pregnant women and their newborn infants with group-B streptococci. Indian J. Med. Microbi. 19, 1-4.
  • Money, D.M., Dobson, S. 2004. The prevention of early-onset neonatal group B streptococcal disease. J. Obstet. Gynaecol. Can. 26, 826–832.
  • Monique, T.S., Jan, K., Louis, K., Bakkers, J., Melchers, W., Spanjaard, L., Wannet, W.J., Hoogkamp-Korstanje, M.A. 2006. Serotypes, geno types and antibiotic susceptibility profiles of group B streptococci causing neonatal sepsis and meningitisbefore and after introduction of antibiotic prophylaxis. Pediatr. Infect. Dis. J. 25, 945-948.
  • Moyo, S.R., Maeland, J.A., Bergh, K. 2002. Typing of human isolates of streptococcus agalactiae (group B streptococcus, gbs) strains from Zimbabwe. J. Med. Microbiol. 51, 595–600.
  • Ölçü, M., Eşel, D. 2007. Antibiotic susceptibilities of clinical streptococcus agalactiae isolates. J. Health Sci. 16, 23-27. 3 Dilek et al.
  • Schrag, S.J., Phil, D., Zywicki, S. Farley, M.M., Reingold, A.L., Harrison, L.H., Lefkowitz, L.B., Hadler, J.L., Danila, R., Cieslak, P.R., Schuchat, A. 2000. Group B streptococcal disease in the era of intrapartum antibiotic prophylaxis. N. Engl. J. Med. 342, 15-20.
  • Topkaya, A., Küçükercan, M., Oğuzoğlu, N., Ünal, N., Narin, K. 2003. Antibiotic susceptibilities of group B streptococci isolated from vaginal and rectal colonization in pregnant women. J. Turk. Microbi. Society. 33, 242-245.
  • Tünger, A., Çavuşoğlu, C., Korkmaz, M. 2005. Group B streptococcus. Asya Microbi. 94-96.
  • Quiroga, M., Pegels, E., Oviedo, P., Pereyra, E., Vergara, M. 2008. Antibiotic susceptibility patterns and prevalence of group B streptococcus isolated from pregnant women in misiones, Argentina. Brazilian J. Microbi. 39, 245-25.
There are 18 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Basic Medical Sciences
Authors

Aziz Dilek

Hasan Kesbiç This is me

Nursel Dilek

Publication Date February 15, 2012
Submission Date December 22, 2010
Published in Issue Year 2011 Volume: 28 Issue: 1

Cite

APA Dilek, A., Kesbiç, H., & Dilek, N. (2012). Antibiotic Susceptibilities of Group B Streptococci. Journal of Experimental and Clinical Medicine, 28(1), 1-3.
AMA Dilek A, Kesbiç H, Dilek N. Antibiotic Susceptibilities of Group B Streptococci. J. Exp. Clin. Med. February 2012;28(1):1-3.
Chicago Dilek, Aziz, Hasan Kesbiç, and Nursel Dilek. “Antibiotic Susceptibilities of Group B Streptococci”. Journal of Experimental and Clinical Medicine 28, no. 1 (February 2012): 1-3.
EndNote Dilek A, Kesbiç H, Dilek N (February 1, 2012) Antibiotic Susceptibilities of Group B Streptococci. Journal of Experimental and Clinical Medicine 28 1 1–3.
IEEE A. Dilek, H. Kesbiç, and N. Dilek, “Antibiotic Susceptibilities of Group B Streptococci”, J. Exp. Clin. Med., vol. 28, no. 1, pp. 1–3, 2012.
ISNAD Dilek, Aziz et al. “Antibiotic Susceptibilities of Group B Streptococci”. Journal of Experimental and Clinical Medicine 28/1 (February 2012), 1-3.
JAMA Dilek A, Kesbiç H, Dilek N. Antibiotic Susceptibilities of Group B Streptococci. J. Exp. Clin. Med. 2012;28:1–3.
MLA Dilek, Aziz et al. “Antibiotic Susceptibilities of Group B Streptococci”. Journal of Experimental and Clinical Medicine, vol. 28, no. 1, 2012, pp. 1-3.
Vancouver Dilek A, Kesbiç H, Dilek N. Antibiotic Susceptibilities of Group B Streptococci. J. Exp. Clin. Med. 2012;28(1):1-3.
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