Kronik B ve C Hepatitli Hastalarda Hepatik Vendeki Doppler Ultrasonografi Bulguları ile Histopatolojik Parametrelerin Karşılaştırılması
Abstract
Bu çalışmada asemptomatik kronik B ve C hepatitli hastalarda hepatik vendeki Doppler ultrasonografi bulgulan ile histopatolojik parametreler karşılaştırarak hastalığın progresyonunun gösterilmesin¬de Doppler Ultrasonografınin başarısı araştırıldı.
Prospektif olarak 43 kronik viral hepatitli ve 25 sağlıklı olguda hepatik vendeki akım formu değerlendirildi. Bulgular sağlıklı ve hepatit gruplan inflamasyon ve fıbrozis açısından derecelere ayrılarak karşılaştırıldı. Hastalar inflamasyon derecesine göre dört gruba (mi¬nimal, hafif, orta ve şiddetli); fıbrozis evrelerine üç gruba (minimal, orta ve şiddetli) ayrıldı.
Hasta grupta hepatik vende trifazik olmayan akım formu sıklı¬ğında anlamlı artış kaydedilmiş, ancak grade ve evre alt gruplarının birbirleri ile karşılaştırılmasında anlamlı farklılık gösterilememiştir.
Hepatik venin Doppler US ile değerlendirilmesi kronik viral hepatitli hastalan saptamada başarılı olmakla birlikte hastalığın progresyonunun gösterilmesinde sınırlı faydaya sahiptir.
Abstract
Wc aimed to compare histopathologic parameters with portal vein and hepatic artery Doppler ultrasonographic (USG) findings to assess progression of disease without need for a biopsy in the asymptomatic hepatitis B and C patients.
This prospectively designed study included 43 chronic hepatitis patients and 25 healthy subjects. Patient group is divided into four subgroups (minimal, mild, modarate and severe) regard to inflammation and three subgroups regarding to fibrosis (mild, moderate and severe). Obtained data from subjects compared between healthy subjects and patient group as well as between subgroups.
Increase in the frequency of non-triphasic flow pattern of hepatic vein were found among patients with chronic hepatitis comparing with the healthy group. However no difference is found between inflammation and fibrosis subgroups about examined indices.
We found that Doppler USG examination of hepatic vein is a sensitive method for identifiying of the chronic viral hepatitis but it has limited value for demostrating disease progression.
References
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- 2.Tekeli E, Balık Î. Viral Hepatit 2003. Viral Hepatitle Savaşım Derneği, 2003: 85-135, 184-199,329-47.
- 3.Patriquin H, Lafortune M, Burns PN, Dazuat M. Duplex Doppler examination in portal hypertension: technique and anatomy. AJR 1987;149:71-6.
- 4.Gill RW. Measurament of blood flow by ultrasound accuracy and sources of error. Ultrasound in Med and Biol 1985; 11:625-41.
- 5.Shapiro RS, Winsberg F, Maldjian C, Pasik AS. Variability of hepatic vein Doppler tracings in normal subjects. J Ultrasound Med 1993; 12:701-3.
- 6.Gorka W, Mulla A, Sebayel M. Qualitative hepatic venous Doppler sonography versus portal flowmetry in predicting the severity of esophageal varices in hepatitis C cirrhosis. AJR 1997 ; 169:511-5
- 7.Hamato N, Moriyasu F, Someda H. Phase shift of the hepatic vein flow velocity waveform in chronic liver disease: experimental and clinical studies. Ultrasound in Med and Biol 1997;23:821-8.
- 8.Bolondi L, Bassi SL, Gaiani S. Liver cirrhosis: Changes of Doppler waveform of hepatic veins. Radiology 1991; 178:513-6.
- 9.Ohta M, Hashizume M, Tamikawa M, Ueno K, Tanoue K, Sugimachi K. Analysis of Hepatic Vein Waveform by Doppler Ultrasonography in 100 patient with portal hypertension. Am J Gastroenterol 1995;80:1853-7.
- 10.Arda K, Ofelli M, Çalikoğlu U, Ölçer T, Cumhur T. Hepatic Vein Doppler Waveform Changes in Early Stage (Child-Pugh A) Chronic Parenchymal Liver Disease. J Clin Ultrasound 1997;25:15-9.
- 11.Colli A, Cocciolo MI, Riva CI, Martinez E. Abnormalities of Doppler waveform of hepatic veins in patients with chronic liver disease. AJR 1994; 162:83 3-7.
Abstract
References
- 1.Dietrich CF, Lee JH, Gottschalk R, Herrmann G. Hepatic and portal vein flow pattern in correlation with intrahepatic fat deposition and liver histology in patients with chronic hepatitis C. AJR 1998; 171:437-43.
- 2.Tekeli E, Balık Î. Viral Hepatit 2003. Viral Hepatitle Savaşım Derneği, 2003: 85-135, 184-199,329-47.
- 3.Patriquin H, Lafortune M, Burns PN, Dazuat M. Duplex Doppler examination in portal hypertension: technique and anatomy. AJR 1987;149:71-6.
- 4.Gill RW. Measurament of blood flow by ultrasound accuracy and sources of error. Ultrasound in Med and Biol 1985; 11:625-41.
- 5.Shapiro RS, Winsberg F, Maldjian C, Pasik AS. Variability of hepatic vein Doppler tracings in normal subjects. J Ultrasound Med 1993; 12:701-3.
- 6.Gorka W, Mulla A, Sebayel M. Qualitative hepatic venous Doppler sonography versus portal flowmetry in predicting the severity of esophageal varices in hepatitis C cirrhosis. AJR 1997 ; 169:511-5
- 7.Hamato N, Moriyasu F, Someda H. Phase shift of the hepatic vein flow velocity waveform in chronic liver disease: experimental and clinical studies. Ultrasound in Med and Biol 1997;23:821-8.
- 8.Bolondi L, Bassi SL, Gaiani S. Liver cirrhosis: Changes of Doppler waveform of hepatic veins. Radiology 1991; 178:513-6.
- 9.Ohta M, Hashizume M, Tamikawa M, Ueno K, Tanoue K, Sugimachi K. Analysis of Hepatic Vein Waveform by Doppler Ultrasonography in 100 patient with portal hypertension. Am J Gastroenterol 1995;80:1853-7.
- 10.Arda K, Ofelli M, Çalikoğlu U, Ölçer T, Cumhur T. Hepatic Vein Doppler Waveform Changes in Early Stage (Child-Pugh A) Chronic Parenchymal Liver Disease. J Clin Ultrasound 1997;25:15-9.
- 11.Colli A, Cocciolo MI, Riva CI, Martinez E. Abnormalities of Doppler waveform of hepatic veins in patients with chronic liver disease. AJR 1994; 162:83 3-7.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Radiology and Organ Imaging |
| Journal Section | Research Article |
| Authors | |
| Publication Date | March 20, 2007 |
| Published in Issue | Year 2007 Volume: 1 Issue: 1 |
