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Oral Prekanseröz Lezyonların Teşhis ve Tedavisi

Yıl 2021, Cilt: 10 Sayı: 3, 159 - 164, 20.09.2021

Nur Mollaoğlu İlkay Peker Dilek Aynur Uğar Çankal Sibel Elif Gültekin Yeliz Kılınç

Öz

Dünya genelinde sık görülen malignansiler sınıflamasında oral kanser ve beraberinde orofaringeal kanserler 6. en sık görülen malignasiler olarak rapor edilmiş olmaktadırlar. Prognozuna bakıldığında oral kanserlerin beş yıllık hayatta kalma oranı %40 olarak bildirilmekle beraber bu oran erken dönemde teşhis ve tedavinin yapılması ile %80’lere çıkarılabilmiştir. Oral kanser risk faktörlerinin çoğu elimine edilebilen faktörler olduğundan oral kanser çoğunlukla önlenebilir bir hastalık olarak düşünülmektedir. Bu nedenle, rutin dental muayeneler sırasında detaylı olarak oral mukoza muayenesi ve beyaz-kırmızı, premalign lezyon varlığının araştırılması, takiben bu lezyonların düzenli takiplerinin yapılması teşhiste meydana gelebilecek gecikmeleri önlemede ve hastanın yaşam şansını arttırmada oldukça önemli olacaktır.

Anahtar Kelimeler

Oral kanser Prekanser Mukozal lezyonlar

Kaynakça

  • 1. Irani S. Metastasis to head and neck area: A 16 year retrospective study. Am J Otolaryngol 2011;32:24 7.
  • 2. Irani S. Herbal medicine and oral health: A review. J Int Oral Health 2016;8:989 94.
  • 3. Nakashima T, Tomita H, Hirata A, Ishida K, Hisamatsu K, Hatano Y, et al. Promotion of cell proliferation by the proto oncogene DEK enhances oral squamous cell carcinogenesis through field cancerization. Cancer Med 2017;6:2424 39.
  • 4. Irani S. Distant metastasis from oral cancer: A review and molecular biologic aspects. J Int Soc Prev Community Dent 2016;6:265 71.
  • 5. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209-49.
  • 6. Sathiasekar AC, Mathew DG, Jaish Lal MS, Arul Prakash AA, Goma Kumar KU. Oral field cancerization and its clinical implications in the management in potentially malignant disorders. J Pharm Bioallied Sci 2017;9:S23-5.
  • 7. Shield KD, Ferlay J, Jemal A, Sankaranarayanan R, Chaturvedi AK, Bray F, et al. The global incidence of lip, oral cavity, and pharyngeal cancers by subsite in 2012. CA Cancer J Clin 2017;67:51-64.
  • 8. Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 2009;45:309–16.
  • 9. MacMonegle AJ, Nonnemaker J, Duke JC, Farrelly MC, Zhao X, Delahanty JC, et al. Cost-Effectiveness Analysis of The Real Cost Campaign's Effect on Smoking Prevention. Am J Prev Med 2018;55:319–25.
  • 10. Hussein AA, Helder MN, de Visscher JG, Leemans CR, Braakhuis BJ, de Vet HCW, et al. Global incidence of oral and oropharynx cancer in patients younger than 45 years versus older patients: A systematic review. Eur J Cancer 2017;82:115–27.
  • 11. Toporcov TN, Znaor A, Zhang ZF, Yu GP, Winn DM, Wei Q, et al. Risk factors for head and neck cancer in young adults: a pooled analysis in the INHANCE consortium. Int J Epidemiol 2015;44:169–85.
  • 12. Llewellyn CD, Johnson NW, Warnakulasuriya KA. Risk factors for squamous cell carcinoma of the oral cavity in young people–a comprehensive literature review. Oral Oncol 2001;37:401–18.
  • 13. Satgunaseelan L, Allanson BM, Asher R, Reddy R, Low HTH, Veness M, et al. The incidence of squamous cell carcinoma of the oral tongue is rising in young non-smoking women: An international multi-institutional analysis. Oral Oncol 2020;110:104875.
  • 14. Kumar M, Nanavati R, Modi TG, Dobariya C. Oral cancer: Etiology and risk factors: A review. J Cancer Res Ther 2016;12:458-63.
  • 15. Sarode G, Maniyar N, Sarode SC, Jafer M, Patil S, Awan KH. Epidemiologic aspects of oral cancer. Dis Mon 2020;66:100988.
  • 16. Alqahtani WS, Almufareh NA, Al-Johani HA, Alotaibi RK, Juliana CI, Aljarba NH, et al. Oral and Oropharyngeal Cancers and Possible Risk Factors Across Gulf Cooperation Council Countries: A Systematic Review. World J Oncol 2020;11:173-81.
  • 17. Irani S. New Insights into Oral Cancer-Risk Factors and Prevention: A Review of Literature. Int J Prev Med 2020;30;11:202.
  • 18. Martín García E, Arias-Santiago S, Serrano-Ortega S, Buendía-Eisman A. Changes in the Incidence of Skin and Lip Cancer Between 1978 and 2007. Actas Dermosifiliogr 2017;108:335-45.
  • 19. Villa A, Villa C, Abati S. Oral cancer and oral erythroplakia: An update and implication for clinicians. Aust Dent J 2011;56:253-6.
  • 20. Rethman MP, Carpenter W, Cohen EE, Epstein J, Evans CA, Flaitz CM, et al. Evidence-Based Clinical Recommendations Regarding Screening for Oral Squamous Cell Carcinomas. J Am Dent Assoc 2010;141:509-20.
  • 21. Bewley AF, Farwell DG. Oral leukoplakia and oral cavity squamous cell carcinoma. Clin Dermatol 2017;35:461-7. 22. Wetzel SL, Wollenberg J. Oral Potentially Malignant Disorders. Dent Clin N Am 2020;64:25-37.
  • 23. Maymone MB, Greer RO, Kesecker J, Sahitya PC, Burdine LK, Cheng AD, et al. Premalignant and Malignant Mucosal Lesions: Clinical and Pathological Findings Part II. J Am Acad Dermatol 2018;81:59-71.
  • 24. Reichart PA, Philipsen HP. Oral erythroplakia: A review. Oral Oncol 2005;41:551-61.
  • 25. Olson MA, Rogers RS, Bruce AJ. Oral lichen planus. Clin Dermatol 2016;34:495-504.
  • 26. Mollaoglu N. Oral Lichen Planus; a review. Br J Oral Maxillofac Surg 2000;38:370-7.
  • 27. Sharma M, Shetty SS, Radhakrishnan R. Oral Submucous Fibrosis as an Overhealing Wound: Implications in Malignant Transformation. Recent Pat Anticancer Drug Discov. 2018;13:272-91.
  • 28. Warnakulasuriya S. Clinical features and presentation of oral potentially malignant disorders. Oral Surg Oral Med Oral Pathol Oral Radiol 2018;125:582-90.
  • 29. Piemonte ED, Lazos JP, Brunotto M. Relationship between chronic trauma of the oral mucosa, oral potentially malignant disorders and oral cancer. J Oral Pathol Med 2010;39:513-7.
  • 30. Pentenero M, Val M, Rosso S, Gandolfo S. Microbiopsy a first-level diagnostic test to rule out oral dysplasia or carcinoma in general dental practice. Oral Dis 2018;24:109-11.
  • 31. Mollaoglu N, Cowpe JG, Walker R. Quantitative cytological analysis of smears collected from lesions clinically resembling oral lichen planus. Cytopathology 2001;12:274-7.
  • 32. Li YN, Lu R, Zhang J, Zhou G. Inter-and intra-observer agreement on the judgment of toluidine blue staining for screening of oral potentially malignant disorders and oral cancer. Clin Oral Investig 2018;23:1709-14.
  • 33. Gupta P. An update on light-based Technologies and fluorescent imaging in oral cancer detection. Oncobiology and Targets 2017;4:1-5.
  • 34. Al-Maweri SA, Halboub E, Warnakulasuriya S. Impact of COVID-19 on the early detection of oral cancer: A special emphasis on high risk populations. Oral Oncol 2020;106:104760.

Diagnosis and Management of Oral Precancerous Lesions

Yıl 2021, Cilt: 10 Sayı: 3, 159 - 164, 20.09.2021

Nur Mollaoğlu İlkay Peker Dilek Aynur Uğar Çankal Sibel Elif Gültekin Yeliz Kılınç

Öz

Oral cancer and accompanying oropharyngeal cancers are reported as the 6th most common malignancies in the worldwide classification of malignancies. Considering the prognosis, the 5-year survival rate of oral cancers is reported as 40%, but this rate can be increased up to 80% by the aid of early diagnosis and treatment. Since most of the risk factors for oral cancer can be eliminated, oral cancer is often considered a preventable disease. Therefore, detailed examination of the oral mucosa and searching the presence of white-red, premalignant lesions during routine dental examinations, and also regular follow-up of these lesions will be very important in preventing delays in diagnosis and consequently increasing the patient's survival.

Anahtar Kelimeler

Oral cancer Precancer Mucosal lesions

Kaynakça

  • 1. Irani S. Metastasis to head and neck area: A 16 year retrospective study. Am J Otolaryngol 2011;32:24 7.
  • 2. Irani S. Herbal medicine and oral health: A review. J Int Oral Health 2016;8:989 94.
  • 3. Nakashima T, Tomita H, Hirata A, Ishida K, Hisamatsu K, Hatano Y, et al. Promotion of cell proliferation by the proto oncogene DEK enhances oral squamous cell carcinogenesis through field cancerization. Cancer Med 2017;6:2424 39.
  • 4. Irani S. Distant metastasis from oral cancer: A review and molecular biologic aspects. J Int Soc Prev Community Dent 2016;6:265 71.
  • 5. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209-49.
  • 6. Sathiasekar AC, Mathew DG, Jaish Lal MS, Arul Prakash AA, Goma Kumar KU. Oral field cancerization and its clinical implications in the management in potentially malignant disorders. J Pharm Bioallied Sci 2017;9:S23-5.
  • 7. Shield KD, Ferlay J, Jemal A, Sankaranarayanan R, Chaturvedi AK, Bray F, et al. The global incidence of lip, oral cavity, and pharyngeal cancers by subsite in 2012. CA Cancer J Clin 2017;67:51-64.
  • 8. Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 2009;45:309–16.
  • 9. MacMonegle AJ, Nonnemaker J, Duke JC, Farrelly MC, Zhao X, Delahanty JC, et al. Cost-Effectiveness Analysis of The Real Cost Campaign's Effect on Smoking Prevention. Am J Prev Med 2018;55:319–25.
  • 10. Hussein AA, Helder MN, de Visscher JG, Leemans CR, Braakhuis BJ, de Vet HCW, et al. Global incidence of oral and oropharynx cancer in patients younger than 45 years versus older patients: A systematic review. Eur J Cancer 2017;82:115–27.
  • 11. Toporcov TN, Znaor A, Zhang ZF, Yu GP, Winn DM, Wei Q, et al. Risk factors for head and neck cancer in young adults: a pooled analysis in the INHANCE consortium. Int J Epidemiol 2015;44:169–85.
  • 12. Llewellyn CD, Johnson NW, Warnakulasuriya KA. Risk factors for squamous cell carcinoma of the oral cavity in young people–a comprehensive literature review. Oral Oncol 2001;37:401–18.
  • 13. Satgunaseelan L, Allanson BM, Asher R, Reddy R, Low HTH, Veness M, et al. The incidence of squamous cell carcinoma of the oral tongue is rising in young non-smoking women: An international multi-institutional analysis. Oral Oncol 2020;110:104875.
  • 14. Kumar M, Nanavati R, Modi TG, Dobariya C. Oral cancer: Etiology and risk factors: A review. J Cancer Res Ther 2016;12:458-63.
  • 15. Sarode G, Maniyar N, Sarode SC, Jafer M, Patil S, Awan KH. Epidemiologic aspects of oral cancer. Dis Mon 2020;66:100988.
  • 16. Alqahtani WS, Almufareh NA, Al-Johani HA, Alotaibi RK, Juliana CI, Aljarba NH, et al. Oral and Oropharyngeal Cancers and Possible Risk Factors Across Gulf Cooperation Council Countries: A Systematic Review. World J Oncol 2020;11:173-81.
  • 17. Irani S. New Insights into Oral Cancer-Risk Factors and Prevention: A Review of Literature. Int J Prev Med 2020;30;11:202.
  • 18. Martín García E, Arias-Santiago S, Serrano-Ortega S, Buendía-Eisman A. Changes in the Incidence of Skin and Lip Cancer Between 1978 and 2007. Actas Dermosifiliogr 2017;108:335-45.
  • 19. Villa A, Villa C, Abati S. Oral cancer and oral erythroplakia: An update and implication for clinicians. Aust Dent J 2011;56:253-6.
  • 20. Rethman MP, Carpenter W, Cohen EE, Epstein J, Evans CA, Flaitz CM, et al. Evidence-Based Clinical Recommendations Regarding Screening for Oral Squamous Cell Carcinomas. J Am Dent Assoc 2010;141:509-20.
  • 21. Bewley AF, Farwell DG. Oral leukoplakia and oral cavity squamous cell carcinoma. Clin Dermatol 2017;35:461-7. 22. Wetzel SL, Wollenberg J. Oral Potentially Malignant Disorders. Dent Clin N Am 2020;64:25-37.
  • 23. Maymone MB, Greer RO, Kesecker J, Sahitya PC, Burdine LK, Cheng AD, et al. Premalignant and Malignant Mucosal Lesions: Clinical and Pathological Findings Part II. J Am Acad Dermatol 2018;81:59-71.
  • 24. Reichart PA, Philipsen HP. Oral erythroplakia: A review. Oral Oncol 2005;41:551-61.
  • 25. Olson MA, Rogers RS, Bruce AJ. Oral lichen planus. Clin Dermatol 2016;34:495-504.
  • 26. Mollaoglu N. Oral Lichen Planus; a review. Br J Oral Maxillofac Surg 2000;38:370-7.
  • 27. Sharma M, Shetty SS, Radhakrishnan R. Oral Submucous Fibrosis as an Overhealing Wound: Implications in Malignant Transformation. Recent Pat Anticancer Drug Discov. 2018;13:272-91.
  • 28. Warnakulasuriya S. Clinical features and presentation of oral potentially malignant disorders. Oral Surg Oral Med Oral Pathol Oral Radiol 2018;125:582-90.
  • 29. Piemonte ED, Lazos JP, Brunotto M. Relationship between chronic trauma of the oral mucosa, oral potentially malignant disorders and oral cancer. J Oral Pathol Med 2010;39:513-7.
  • 30. Pentenero M, Val M, Rosso S, Gandolfo S. Microbiopsy a first-level diagnostic test to rule out oral dysplasia or carcinoma in general dental practice. Oral Dis 2018;24:109-11.
  • 31. Mollaoglu N, Cowpe JG, Walker R. Quantitative cytological analysis of smears collected from lesions clinically resembling oral lichen planus. Cytopathology 2001;12:274-7.
  • 32. Li YN, Lu R, Zhang J, Zhou G. Inter-and intra-observer agreement on the judgment of toluidine blue staining for screening of oral potentially malignant disorders and oral cancer. Clin Oral Investig 2018;23:1709-14.
  • 33. Gupta P. An update on light-based Technologies and fluorescent imaging in oral cancer detection. Oncobiology and Targets 2017;4:1-5.
  • 34. Al-Maweri SA, Halboub E, Warnakulasuriya S. Impact of COVID-19 on the early detection of oral cancer: A special emphasis on high risk populations. Oral Oncol 2020;106:104760.
Toplam 33 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Diş Hekimliği
Bölüm Editörden
Yazarlar

Nur Mollaoğlu 0000-0003-2686-2955

İlkay Peker 0000-0002-2888-2979

Dilek Aynur Uğar Çankal 0000-0003-0043-9315

Sibel Elif Gültekin 0000-0002-0732-3617

Yeliz Kılınç 0000-0003-2853-7830

Yayımlanma Tarihi 20 Eylül 2021
Gönderilme Tarihi 30 Ağustos 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 10 Sayı: 3

Kaynak Göster

Vancouver Mollaoğlu N, Peker İ, Uğar Çankal DA, Gültekin SE, Kılınç Y. Oral Prekanseröz Lezyonların Teşhis ve Tedavisi. ADO Klinik Bilimler Dergisi. 2021;10(3):159-64.
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