Derleme
Yıl 2020,
Cilt: 29 Sayı: 3, 209 - 217, 30.09.2020
Öz
Inflammation
is the response of immune system cells to tissue damage. Infection is caused by
the presence of microorganisms. Acute and chronic osteomyelitis,
spondylodiscitis and orthopedic implant infections are a heterogeneous group of
infectious diseases. Common feature of these diseases is diagnosis and treatment
of them is made by clinicians, radiologists and nuclear medicine physicians.
Early diagnosis and localization of the infection is important to perform
appropriate and early treatment. Pathological processes in ttissue after
infection is shown with radiological methods. However nuclear medicine methods
have great importance for the determination of the infection focus in cases
with the infection is at the cellular level. Radiopharmaceuticals such as Gallium-67
citrate, Technetium-99m (Tc-99m) nanocolloid and Tc-99m diphosphonate
derivatives are commonly used for infection imaging. This article aims to underline
importance of molecular imaging methods for diagnosis of orthopedics infections
and guidance for clinicians in clinical practice.
Anahtar Kelimeler
Proje Numarası
Yok
Kaynakça
- 1. Ziessman H, O'Malley J, Thrall J. Nuclear Medicine: The Reguisities. 4th ed. Philadelphia, Elseiver, 2014.
- 2. Alazraki NP. Diagnosing prosthetic joint infection. J Nucl Med. 1990;31(12):1955-7.
- 3. van der Bruggen W, Bleeker-Rovers CP, Boerman OC, Gotthardt M, Oyen WJ. PET and SPECT in osteomyelitis and prosthetic bone and joint infections: a systematic review. Semin Nucl Med. 2010;40(1):3-15.
- 4. Elgazzar AH. The pathophysiologic basic of nuclear medicine. 2nd. ed. New York, Springer, 2006.
- 5. Cook GJR, Maisey MN, Britton KE, Chengazi V. Clinical Nuclear Medicine. 4th ed. London, 2006.
- 6. Gemmel F, Dumarey N, Welling M. Future diagnostic agents. Semin Nucl Med. 2009;39(1):11-26.
- 7. Sharp PF, Gemmell HG, Murray AD. Practical Nuclear Medicine.3rd ed. London, Springer, 2005.
- 8. De Winter F, Gemmel F, Van Laere K, De Winter O, Poffijn B, Dierckx RA et al. 99mTc-ciprofloxacin planar and tomographic imaging for the diagnosis of infection in the postoperative spine: experience in 48 patients. Eur J Nucl Med Mol Imaging. 2004;31(2):233-9.
- 9. Palestro CJ. Radionuclide imaging of osteomyelitis. Semin Nucl. Med. 2015;45:32-46.
- 10. Wukich DK, Abreu SH, Callaghan JJ, Van Nostrand D, Savory CG, Eggli DF et al. Diagnosis of infection by preoperative scintigraphy with indium-labeled white blood cells. J Bone Joint Surg Am. 1987;69(9):1353-60.
- 11. Palestro CJ, Love C, Tronco GG, Tomas MB, Rini JN. Combined labeled leukocyte and technetium99m sulfur colloid bone marrow imaging for diagnosing musculoskeletal infection. Radiographics;2006;26(3):859-70.
- 12. Palestro CJ. Nuclear medicine, the painful prosthetic joint, and orthopedic infection. J Nucl Med. 2003;44(6):927-9.
- 13. Zhuang H, Duarte PS, Pourdehnad M, Maes A, Van Acker F, Shnier D et al. The promising role of 18F-FDG PET in detecting infected lower limb prosthesis implants, J Nucl Med. 2001;42(1):44-48.
- 14. Reinartz P, Mumme T, Hermanns B, Cremerius U, Wirtz DC, Schaefer WM et al. Radionuclide imaging of the painful hip arthroplasty: positron-emission tomography versus triple-phase bone scanning. J Bone Joint Surg Br. 2005;87(4):465-70.
- 15. Volpe L, Indellı PF, Latella L, Poli P, Yakupoglu J, Marcucci M. Periprosthetic joint infections: a clinical practice algorithm. Joints. 2015;2(4):169-74.
- 16. Love C, Marwin SE, Palestro CJ. Nuclear medicine and the infected joint replacement. Semin Nucl Med. 2009;39(1):66-78.
- 17. Merkel KD, Brown ML, Fitzgerald RH Jr. Sequential technetium-99m HMDP-gallium-67 citrate imaging for the evaluation of infection in the painful prosthesis. J Nucl Med. 1986;27(9):1413-7.
- 18. Kraemer WJ, Saplys R, Waddell JP, Morton J. Bone scan, gallium scan, and hip aspiration in the diagnosis of infected total hip arthroplasty. J Arthroplasty. 1993;8(6):611-6.
- 19. Lieberman JR, Huo MH, Schneider R, Salvati EA, Rodi S. Evaluation of painful hip arthroplasties. Are technetium bone scans necessary? J Bone Joint Surg Br. 1993;75(3): 475-8.
- 20. Rushton N, Coakley AJ, Tudor J, Wraight EP. The value of technetium and gallium scanning in assessing pain after total hip replacement. J Bone Joint Surg Br. 1982;64(3):313-8.
- 21. Palestro CJ. Nuclear medicine and the failed joint replacement: Past, present, and future. World J Radiol. 2014;28;6(7):446-58.
- 22. Love C, Marwin SE, Tomas MB, Krauss ES, Tronco GG, Bhargava KK et al. Diagnosing infection in the failed joint replacement: a comparison of coincidence detection 18F-FDG and 111In-labeled leukocyte/99Tc-sulfur colloid marrow imaging. J Nucl Med. 2004;45(11):1864-71.
- 23. Johnson JA, Christie MJ, Sandler MP, Parks PF Jr, Homra L, Kaye JJ. Detection of occult infection following total joint artroplasty using sequential technetium-99m HDP bone scintigraphy and indium-111 WBC imaging. J Nucl Med. 1998;29(8):1347-53.
- 24. Pelosi E, Baiocco C, Pennone M, Migliaretti G, Varetto T, Maiello A et al. 99mTc-HMPAO-leukocyte scintigraphy in patients with symptomatic total hip or knee arthroplasty: improved diagnostic accuracy by means of semiquantitative evaluation. J Nucl Med. 2004;45(3):438-44.
- 25. Love C, Tomas MB, Marwin SE, Pugliese PV, Palestro CJ. Role of nuclear medicine in diagnosis of the infected joint replacement. Radiographics. 2001;21(5):1229-38.
- 26. Rosenthall L, Lepanto L, Raymond F. Radiophosphate uptake in asymptomatic knee artroplasty. J Nucl Med. 1987;28(10):1546-9.
- 27. Yue B, Tang T. The use of nuclear imaging for the diagnosis of periprosthetic infection after knee and hip arthroplasties. Nucl Med Commun. 2015;36(4):305-11.
- 28. Pring DJ, Henderson RG, Keshavarzian A, Rivett AG, Krausz T, Coombs RR et al. Indium-granulocyte scanning in the painful prosthetic joint, AJR Am J Roentgenol. 1986;147(1):167-72.
- 29. Palestro CJ, Love C. Role of Nuclear Medicine for Diagnosing Infection of Recently Implanted Lower Extremity Arthroplasties. Semin Nucl Med. 2017;47(6):630-638.
- 30. Palestro CJ, Kim CK, Swyer AJ, Capozzi JD, Solomon RW, Goldsmith SJ. Total-hip arthroplasty: periprosthetic indium-111-labeled leukocyte activity and complementary technetium-99m-sulfur colloid imaging in suspected infection. J Nucl Med. 1990;31(12):1950-5.
- 31. De Winter F, Van de Wiele C, Dumont F, Van Durme J, Solanki K, Britton K et al. Biodistribution and dosimetry of 99mTc-ciprofloxacin, a promising agent for the diagnosis of bacterial infection. Eur J Nucl Med. 2001;28(5):570-4.
Yıl 2020,
Cilt: 29 Sayı: 3, 209 - 217, 30.09.2020
Öz
İnflamasyon, immun sistem hücrelerinin doku hasarına karşı
yanıtıdır. Enfeksiyon, mikroorganizmaların varlığı ile meydana gelir. Akut ve
kronik osteomiyelit, spondilodiskit ve ortopedik implant enfeksiyonları
enfeksiyöz hastalıkların heterojen grubudur. Bu hastalıkların ortak yönü
klinisyen, radyolog ve nükleer tıp hekimleri tarafından tanı ve tedavisinin yapılmasıdır. Enfeksiyonun erken tanısı ve
lokalizasyonu, tedavinin uygun ve erken
zamanda yapılabilmesi için önem
taşımaktadır. Enfeksiyon sonrası dokuda oluşan patoloji radyolojik yöntemlerle
gösterilmektedir. Fakat enfeksiyonun hücresel düzeyde olduğu durumlarda
enfeksiyon odağının belirlenmesi açısından nükleer tıp yöntemlerinin önemi
büyüktür. Galyum-67 sitrat, Teknesyum-99m (Tc-99m) nanokolloid ve Tc-99m difosfonat türevleri gibi
radyofarmasötikler enfeksiyon görüntülemede sık kullanılmaktadır. Bu makalede ortopedik
enfeksiyonların tanısında moleküler görüntüleme yöntemlerinin öneminin
vurgulanması ve klinik pratikte klinisyenlere yol gösterici olması amaçlanmıştır.
Anahtar Kelimeler
Destekleyen Kurum
Yok
Proje Numarası
Yok
Teşekkür
Yok
Kaynakça
- 1. Ziessman H, O'Malley J, Thrall J. Nuclear Medicine: The Reguisities. 4th ed. Philadelphia, Elseiver, 2014.
- 2. Alazraki NP. Diagnosing prosthetic joint infection. J Nucl Med. 1990;31(12):1955-7.
- 3. van der Bruggen W, Bleeker-Rovers CP, Boerman OC, Gotthardt M, Oyen WJ. PET and SPECT in osteomyelitis and prosthetic bone and joint infections: a systematic review. Semin Nucl Med. 2010;40(1):3-15.
- 4. Elgazzar AH. The pathophysiologic basic of nuclear medicine. 2nd. ed. New York, Springer, 2006.
- 5. Cook GJR, Maisey MN, Britton KE, Chengazi V. Clinical Nuclear Medicine. 4th ed. London, 2006.
- 6. Gemmel F, Dumarey N, Welling M. Future diagnostic agents. Semin Nucl Med. 2009;39(1):11-26.
- 7. Sharp PF, Gemmell HG, Murray AD. Practical Nuclear Medicine.3rd ed. London, Springer, 2005.
- 8. De Winter F, Gemmel F, Van Laere K, De Winter O, Poffijn B, Dierckx RA et al. 99mTc-ciprofloxacin planar and tomographic imaging for the diagnosis of infection in the postoperative spine: experience in 48 patients. Eur J Nucl Med Mol Imaging. 2004;31(2):233-9.
- 9. Palestro CJ. Radionuclide imaging of osteomyelitis. Semin Nucl. Med. 2015;45:32-46.
- 10. Wukich DK, Abreu SH, Callaghan JJ, Van Nostrand D, Savory CG, Eggli DF et al. Diagnosis of infection by preoperative scintigraphy with indium-labeled white blood cells. J Bone Joint Surg Am. 1987;69(9):1353-60.
- 11. Palestro CJ, Love C, Tronco GG, Tomas MB, Rini JN. Combined labeled leukocyte and technetium99m sulfur colloid bone marrow imaging for diagnosing musculoskeletal infection. Radiographics;2006;26(3):859-70.
- 12. Palestro CJ. Nuclear medicine, the painful prosthetic joint, and orthopedic infection. J Nucl Med. 2003;44(6):927-9.
- 13. Zhuang H, Duarte PS, Pourdehnad M, Maes A, Van Acker F, Shnier D et al. The promising role of 18F-FDG PET in detecting infected lower limb prosthesis implants, J Nucl Med. 2001;42(1):44-48.
- 14. Reinartz P, Mumme T, Hermanns B, Cremerius U, Wirtz DC, Schaefer WM et al. Radionuclide imaging of the painful hip arthroplasty: positron-emission tomography versus triple-phase bone scanning. J Bone Joint Surg Br. 2005;87(4):465-70.
- 15. Volpe L, Indellı PF, Latella L, Poli P, Yakupoglu J, Marcucci M. Periprosthetic joint infections: a clinical practice algorithm. Joints. 2015;2(4):169-74.
- 16. Love C, Marwin SE, Palestro CJ. Nuclear medicine and the infected joint replacement. Semin Nucl Med. 2009;39(1):66-78.
- 17. Merkel KD, Brown ML, Fitzgerald RH Jr. Sequential technetium-99m HMDP-gallium-67 citrate imaging for the evaluation of infection in the painful prosthesis. J Nucl Med. 1986;27(9):1413-7.
- 18. Kraemer WJ, Saplys R, Waddell JP, Morton J. Bone scan, gallium scan, and hip aspiration in the diagnosis of infected total hip arthroplasty. J Arthroplasty. 1993;8(6):611-6.
- 19. Lieberman JR, Huo MH, Schneider R, Salvati EA, Rodi S. Evaluation of painful hip arthroplasties. Are technetium bone scans necessary? J Bone Joint Surg Br. 1993;75(3): 475-8.
- 20. Rushton N, Coakley AJ, Tudor J, Wraight EP. The value of technetium and gallium scanning in assessing pain after total hip replacement. J Bone Joint Surg Br. 1982;64(3):313-8.
- 21. Palestro CJ. Nuclear medicine and the failed joint replacement: Past, present, and future. World J Radiol. 2014;28;6(7):446-58.
- 22. Love C, Marwin SE, Tomas MB, Krauss ES, Tronco GG, Bhargava KK et al. Diagnosing infection in the failed joint replacement: a comparison of coincidence detection 18F-FDG and 111In-labeled leukocyte/99Tc-sulfur colloid marrow imaging. J Nucl Med. 2004;45(11):1864-71.
- 23. Johnson JA, Christie MJ, Sandler MP, Parks PF Jr, Homra L, Kaye JJ. Detection of occult infection following total joint artroplasty using sequential technetium-99m HDP bone scintigraphy and indium-111 WBC imaging. J Nucl Med. 1998;29(8):1347-53.
- 24. Pelosi E, Baiocco C, Pennone M, Migliaretti G, Varetto T, Maiello A et al. 99mTc-HMPAO-leukocyte scintigraphy in patients with symptomatic total hip or knee arthroplasty: improved diagnostic accuracy by means of semiquantitative evaluation. J Nucl Med. 2004;45(3):438-44.
- 25. Love C, Tomas MB, Marwin SE, Pugliese PV, Palestro CJ. Role of nuclear medicine in diagnosis of the infected joint replacement. Radiographics. 2001;21(5):1229-38.
- 26. Rosenthall L, Lepanto L, Raymond F. Radiophosphate uptake in asymptomatic knee artroplasty. J Nucl Med. 1987;28(10):1546-9.
- 27. Yue B, Tang T. The use of nuclear imaging for the diagnosis of periprosthetic infection after knee and hip arthroplasties. Nucl Med Commun. 2015;36(4):305-11.
- 28. Pring DJ, Henderson RG, Keshavarzian A, Rivett AG, Krausz T, Coombs RR et al. Indium-granulocyte scanning in the painful prosthetic joint, AJR Am J Roentgenol. 1986;147(1):167-72.
- 29. Palestro CJ, Love C. Role of Nuclear Medicine for Diagnosing Infection of Recently Implanted Lower Extremity Arthroplasties. Semin Nucl Med. 2017;47(6):630-638.
- 30. Palestro CJ, Kim CK, Swyer AJ, Capozzi JD, Solomon RW, Goldsmith SJ. Total-hip arthroplasty: periprosthetic indium-111-labeled leukocyte activity and complementary technetium-99m-sulfur colloid imaging in suspected infection. J Nucl Med. 1990;31(12):1950-5.
- 31. De Winter F, Van de Wiele C, Dumont F, Van Durme J, Solanki K, Britton K et al. Biodistribution and dosimetry of 99mTc-ciprofloxacin, a promising agent for the diagnosis of bacterial infection. Eur J Nucl Med. 2001;28(5):570-4.
Toplam 31 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Derleme |
| Yazarlar | |
| Proje Numarası | Yok |
| Yayımlanma Tarihi | 30 Eylül 2020 |
| Kabul Tarihi | 11 Nisan 2020 |
| Yayımlandığı Sayı | Yıl 2020 Cilt: 29 Sayı: 3 |
