Öz
Amaç: COVID-19 hızla yayılan bir viral hastalık olarak Dünya Sağlık Örgütü tarafından pandemik bir hastalık olarak ilan edildi. Özellikle pnömoni, nekrotizan ensefalopati, sistemik ve pulmoner tromboembolizm, akut solunum sıkıntısı sendromu, sistemik inflamatuar yanıt ve sepsis gibi ciddi sağlık sorunlarına neden olabilmektedir. Çalışmanın amacı, kısa sürede küresel olarak hızla genişleyen koronavirüs hastalığı salgınına bir ilçe hastanesi çerçevesinde genel bir bakış sunmaktadır.
Gereç ve Yöntemler: Mart/2020-Mayıs/2020 tarihleri arasında XX Devlet Hastanesinde, COVID-19 polikliniğine ve acil servise başvuran olası veya kesin COVID-19 erişkin vakalarının, klinik-laboratuvar-görüntüleme verileri, komorbid durumları, hastalık seyri ve medikal tedavileri retrospektif olarak toplandı.
Bulgular: Başvuran 650 hastadan olası/kesin COVİD-19 tanısı olan 471 hasta çalışmaya alındı. Yetmiş üç hasta yatırılarak takip edildi ve yatırılan hastaların sekizi (%1,7) mortal seyretti. Hastalarımızın çoğunluğunun erkek (n=260, %55,2) ve yaş ortancasının da 42 (95%CI: 42.7-45.8) (aralık 18-99 yaş) olarak tespit edildi. Hipertansiyon, diyabet ve kronik obstrüktif akciğer hastalığı en sık üç komorbidite olduğu ve mortal seyreden hastaların en az bir ek hastalığı olduğu görüldü. Tomografide en sık akciğerin <%5'inin ve %5-25'inin tutulumu olduğu görülmektedir.
Sonuç: Küçük bir bölgede ve kısa bir süreçte yapılan çalışmamızın verileri o günün literatür verileriyle benzerlikler içermektedir. Çalışmamızın sonucu olarak hastalığın yaş verileri dahilinde, pandeminin ilk günlerindeki bilgilerden farklı olarak, hastaların çoğunun 65 yaş altı olduğu görülmüştür.
Anahtar Kelimeler
Destekleyen Kurum
yok
Proje Numarası
proje değil
Teşekkür
Özel bir teşekkür bulunmuyor
Kaynakça
- Yan Y, Shin WI, Pang Y.X, et al. The First 75 Days of Novel Coronavirus (SARS-CoV-2) Outbreak: Recent Advances, Prevention, and Treatment. Int J Environ Res Public Health. 2020;17(7):2323.
- Xu Z, Shi L, Wang Y, et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med. 2020;8(4):420-422.
- Yang Y, Islam MS, Wang J, et al. Traditional Chinese Medicine in the Treatment of Patients Infected with 2019-New Coronavirus (SARS-CoV-2): A Review and Perspective. Int J Biol Sci. 2020;16(10):1708-1717.
- WHO [internet]: WHO Director-General's opening remarks at the media briefing on COVID-19-11 March 2020 [Erişim 28.02.2021] Acess link: https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020.
- Wu Z, McGoogan JM. Characteristics of and Important Lessons from the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020;323(13):1239–1242.
- Ai T, Yang Z, Hou H, et al. Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020;296(2):32-40.
- Huang P, Liu T, Huang L, et al. Use of Chest CT in Combination with Negative RT-PCR Assay for the 2019 Novel Coronavirus but High Clinical Suspicion. Radiology. 2020;295(1):22-23.
- Simpson S, Kay FU, Simpson A.S, et al. Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA. J Thorac Imaging. 2020; 2(2): e200152.
- Guan W, Ni Z, Hu Y, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020; 382:1708-1720.
- Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054-1062.
- Salehi S, Abedi A, Balakrishnan S, et al. Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients. AJR Am J Roentgenol. 2020:1-7.
- Prokop M, Van Everdingen W, van Rees Vellinga T, et al. CO-RADS-A categorical CT assessment scheme for patients with suspected COVID-19: definition and evaluation. Radiology. 2020; 296:2, E97-E104.
- Salehi S, Abedi A, Balakrishnan S, et al. Coronavirus disease 2019 (COVID-19) imaging reporting and data system (COVID-RADS) and common lexicon: a proposal based on the imaging data of 37 studies. Eur Radiol. 2020; 30:4930–4942.
- T.C. Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü [internet]: TCSBHSG: COVID-19 (SARS-CoV-2 Enfeksiyonu) Rehberi, Bilim Kurulu Çalışmasi. [Erişim Tarihi:14.04.2020] Erişim linki: https://www.teb.org.tr/versions_latest/1240/13 nisansbrehberi.
- Li K, Fang Y, Li W, et al. CT image visual quantitative evaluation and clinical classification of coronavirus disease (COVID-19). Eur Radiol. 2020; 30(8):4407-4416.
- WHO [internet] WHO: Coronavirus disease (COVID-19) pandemic. [Avaliable 28.02.2021] https://www.who.int/emergencies/diseases/novel-coronavirus 2019?gclid=EAIaIQobChMI-KqN14eN7wIVhfdRCh1UVwcxEAAYASAAEgLMx_D_BwE
- Xu X, Ong YK, Wang DY. Role of adjunctive treatment strategies in COVID-19 and a review of international and national clinical guidelines. Mil Med Res. 2020;7(1):22-22.
- Alsharif W, Qurashi A. Effectiveness of COVID-19 diagnosis and management tools: A review. Radiography (Lond). 2021 May;27(2):682-687. doi: 10.1016/j.radi.2020.09.010.
- Gosch M, Singler K, Kwetkat A, et al. Geriatrics in times of corona. Z Gerontol Geriatr. 2020, 53(3):228-232.
- Fang Y, Zhang H, Xie J, et al: Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR. Radiology. 2020:200432.
- Bernheim A, Mei X, Huang M, et al. Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection. Radiology. 2020;295(3):200463.
- Obadina ET, Torrealba JM, Kanne JP. Acute pulmonary injury: high-resolution CT and histopathological spectrum. Br J Radiol. 2013;86(1027):20120614.
- Chung M, Bernheim A, Mei X, et al. CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV). Radiology 2020;295(1):202-207.
- Guan W.Ni Z.Hu Y.Liang W.Ou C.He J.et al.Clinical characteristics of 2019 novel coronavirus infection in China.medRxiv. 2020;https://doi.org/10.1101/2020.02.06.20020974)
- Li, Lin, Lixin Qin, Zeguo Xu, Youbing Yin, Xin Wang, Bin Kong, Junjie Bai et al. "Artificial intelligence distinguishes COVID-19 from community acquired pneumonia on chest CT." Radiology (2020).
- Bai HX, Hsieh B, Xiong Z, et al. Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT. Radiology 2020:200823.
- Tu Y-F, Chien C-S, Yarmishyn AA, et al. A Review of SARS-CoV-2 and the Ongoing Clinical Trials. Int J Mol Sci. 2020;21(7):2657.
Öz
Aim: COVID-19 was declared a pandemic disease by the World Health Organization as a rapidly spreading viral disease. It can cause serious health problems such as pneumonia, necrotizing encephalopathy, systemic and pulmonary thromboembolism, acute respiratory distress syndrome, systemic inflammatory response, and sepsis. The study aims to provide an overview of the rapidly expanding global coronavirus disease epidemic within the framework of a district hospital.
Material and Methods: The clinical-laboratory-imaging data, comorbid conditions, disease course, and the medical treatments of probable or definite COVID-19 adult cases admitted to the COVID-19 outpatient clinic and emergency service between March/2020-May/2020 were collected retrospectively.
Results: Of the 650 admitted patients, 471 patients with a probable/definite diagnosis of COVID-19 were included in the study. Seventy-three patients were hospitalized, and eight of the hospitalized patients (1.7%) died. The majority of our patients were male (n = 260, 55.2%) and the median age was 42±17.2 years (IQR:24, range 18-99 years). It was determined that hypertension, diabetes, and chronic obstructive pulmonary disease were the three most common comorbidities. Patients with mortality had at least one additional disease. On tomography, the most common lung involvement is <5% and 5-25% of the lung.
Conclusion: The data of our study, which was conducted in a small area and a short period of time, contains similarities with the literature data of that day. As a result of our study, within the age data of the disease, unlike the information in the first days of the pandemic, it was seen that most of the patients were under 65 years old.
Anahtar Kelimeler
Proje Numarası
proje değil
Kaynakça
- Yan Y, Shin WI, Pang Y.X, et al. The First 75 Days of Novel Coronavirus (SARS-CoV-2) Outbreak: Recent Advances, Prevention, and Treatment. Int J Environ Res Public Health. 2020;17(7):2323.
- Xu Z, Shi L, Wang Y, et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med. 2020;8(4):420-422.
- Yang Y, Islam MS, Wang J, et al. Traditional Chinese Medicine in the Treatment of Patients Infected with 2019-New Coronavirus (SARS-CoV-2): A Review and Perspective. Int J Biol Sci. 2020;16(10):1708-1717.
- WHO [internet]: WHO Director-General's opening remarks at the media briefing on COVID-19-11 March 2020 [Erişim 28.02.2021] Acess link: https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020.
- Wu Z, McGoogan JM. Characteristics of and Important Lessons from the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020;323(13):1239–1242.
- Ai T, Yang Z, Hou H, et al. Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020;296(2):32-40.
- Huang P, Liu T, Huang L, et al. Use of Chest CT in Combination with Negative RT-PCR Assay for the 2019 Novel Coronavirus but High Clinical Suspicion. Radiology. 2020;295(1):22-23.
- Simpson S, Kay FU, Simpson A.S, et al. Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA. J Thorac Imaging. 2020; 2(2): e200152.
- Guan W, Ni Z, Hu Y, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020; 382:1708-1720.
- Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054-1062.
- Salehi S, Abedi A, Balakrishnan S, et al. Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients. AJR Am J Roentgenol. 2020:1-7.
- Prokop M, Van Everdingen W, van Rees Vellinga T, et al. CO-RADS-A categorical CT assessment scheme for patients with suspected COVID-19: definition and evaluation. Radiology. 2020; 296:2, E97-E104.
- Salehi S, Abedi A, Balakrishnan S, et al. Coronavirus disease 2019 (COVID-19) imaging reporting and data system (COVID-RADS) and common lexicon: a proposal based on the imaging data of 37 studies. Eur Radiol. 2020; 30:4930–4942.
- T.C. Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü [internet]: TCSBHSG: COVID-19 (SARS-CoV-2 Enfeksiyonu) Rehberi, Bilim Kurulu Çalışmasi. [Erişim Tarihi:14.04.2020] Erişim linki: https://www.teb.org.tr/versions_latest/1240/13 nisansbrehberi.
- Li K, Fang Y, Li W, et al. CT image visual quantitative evaluation and clinical classification of coronavirus disease (COVID-19). Eur Radiol. 2020; 30(8):4407-4416.
- WHO [internet] WHO: Coronavirus disease (COVID-19) pandemic. [Avaliable 28.02.2021] https://www.who.int/emergencies/diseases/novel-coronavirus 2019?gclid=EAIaIQobChMI-KqN14eN7wIVhfdRCh1UVwcxEAAYASAAEgLMx_D_BwE
- Xu X, Ong YK, Wang DY. Role of adjunctive treatment strategies in COVID-19 and a review of international and national clinical guidelines. Mil Med Res. 2020;7(1):22-22.
- Alsharif W, Qurashi A. Effectiveness of COVID-19 diagnosis and management tools: A review. Radiography (Lond). 2021 May;27(2):682-687. doi: 10.1016/j.radi.2020.09.010.
- Gosch M, Singler K, Kwetkat A, et al. Geriatrics in times of corona. Z Gerontol Geriatr. 2020, 53(3):228-232.
- Fang Y, Zhang H, Xie J, et al: Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR. Radiology. 2020:200432.
- Bernheim A, Mei X, Huang M, et al. Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection. Radiology. 2020;295(3):200463.
- Obadina ET, Torrealba JM, Kanne JP. Acute pulmonary injury: high-resolution CT and histopathological spectrum. Br J Radiol. 2013;86(1027):20120614.
- Chung M, Bernheim A, Mei X, et al. CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV). Radiology 2020;295(1):202-207.
- Guan W.Ni Z.Hu Y.Liang W.Ou C.He J.et al.Clinical characteristics of 2019 novel coronavirus infection in China.medRxiv. 2020;https://doi.org/10.1101/2020.02.06.20020974)
- Li, Lin, Lixin Qin, Zeguo Xu, Youbing Yin, Xin Wang, Bin Kong, Junjie Bai et al. "Artificial intelligence distinguishes COVID-19 from community acquired pneumonia on chest CT." Radiology (2020).
- Bai HX, Hsieh B, Xiong Z, et al. Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT. Radiology 2020:200823.
- Tu Y-F, Chien C-S, Yarmishyn AA, et al. A Review of SARS-CoV-2 and the Ongoing Clinical Trials. Int J Mol Sci. 2020;21(7):2657.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Klinik Tıp Bilimleri |
| Bölüm | Orijinal Çalışma |
| Yazarlar | |
| Proje Numarası | proje değil |
| Yayımlanma Tarihi | 30 Haziran 2022 |
| Yayımlandığı Sayı | Yıl 2022 Cilt: 5 Sayı: 2 |
