Araştırma Makalesi
Yıl 2020,
Cilt: 29 Sayı: 1, 95 - 104, 30.06.2020
Öz
Kaynakça
- Mohammed, F.S., Sevindik, M., Bal, C. and Z. Selamoglu, Biological Activities of Adiantum capillus-veneris Collected From Duhok Province (Iraq). Communications Faculty of Sciences University of Ankara Series C Biology, 28(2), (2019) 128-142.
- Mohammed, F.S., Karakaş, M., Akgül, H. and M. Sevindik, Medicinal Properties of Allium calocephalum Collected from Gara Mountain (Iraq). Fresen Environ Bull, 28(10), (2019) 7419-7426.
- Sevindik, M., Akgul, H., Pehlivan, M. and Z. Selamoglu, Determination of therapeutic potential of Mentha longifolia ssp. longifolia. Fresen Environ Bull, 26(7), (2017) 4757-4763.
- Ekim, T., Teucrium L. In: Davis PH, editor. Flora of Turkey and the East Aegean Islands, Vol. 7. Edinburgh, UK: Edinburgh University Press, pp. 58. 1982.
- Cantino, P.D., Harley, R.M. and S.J. Wagstaff, Genera of Labiatae: status and classification. In: Harley RM, Reynolds T, editors. Advances in Labiate Science. Kew, UK: Royal Botanic Gardens, pp. 511–522. 1992.
- Navarro, T. and J. El Oualidi, Trichome morphology in Teucrium L. (Labiatae). A taxonomic review. Anales Jardin Botanico De Madrid, 57, (2000) 277–297.
- Lakušić, B., Stevanović, B., Jančić, R. and D. Lakušić, Habitat-related adaptations in morphology and anatomy of Teucrium (Lamiaceae) species from the Balkan peninsula (Serbia and Montenegro). Flora-Morphology, Distribution, Functional Ecology of Plants, 205(10), (2010) 633-646.
- El Atki, Y., Aouam, I., El Kamari, F., Taroq, A., Lyoussi, B., Oumokhtar, B. and A. Abdellaoui, Phytochemistry, antioxidant and antibacterial activities of two Moroccan Teucrium polium L. subspecies: Preventive approach against nosocomial infections. Arabian Journal of Chemistry, (2019) https://doi.org/10.1016/j.arabjc.2019.04.001
- Elmasri, W.A., Hegazy, M.E.F., Mechref, Y. and P.W. Paré, Structure-antioxidant and anti-tumor activity of Teucrium polium phytochemicals. Phytochemistry letters, 15, (2016) 81-87.
- Aksoy Sagirli, P., Ozsoy, N., Ecevit-Genc, G. and G. Melikoglu, In vitro antioxidant activity, cyclooxygenase-2, thioredoxin reductase inhibition and DNA protection properties of Teucrium sandrasicum L. Industrial Crops and Products, 74, (2015) 545-550.
- Yalcin, A., Yumrutas, O., Kuloglu, T., Elibol, E., Parlar, A., Yilmaz, İ., Pehlivan, M., Dogukan, M., Uckardes, F., Aydin, H., Turk, A., Uludag, O., Sahin, İ., Ugur, K. and S. Aydin, Hepatoprotective properties for Salvia cryptantha extract on carbon tetrachloride-induced liver injury. Cellular and molecular biology, 63(12), (2017) 56-62.
- Gaulejac, N.S., Provost, C. and N. Vivas, Comparative study of polyphenol scavenging activities assessed by different methods. Journal of Agricultural and food Chemistry, 47(2), (1999) 425-431.
- Lee, J.C., Kim, H.R., Kim, J. and Y.S. Jang, Antioxidant property of an ethanol extract of the stem of Opuntia ficus-indica var. saboten. Journal of agricultural and food chemistry, 50(22), (2002) 6490-6496.
- Sharififar, F., Dehghn-Nudeh, G. and M. Mirtajaldini, Major flavonoids with antioxidant activity from Teucrium polium L. Food Chemistry, 112(4), (2009) 885-888.
- Çakir, A., Mavi, A., Kazaz, C., Yildirim, A, Küfrevioğlu Öİ. Antioxidant activities of the extracts and components of Teucrium orientale L. var. orientale. Turkish Journal of Chemistry, 30(4), (2006) 483-494.
- von Sonntag, C., The chemical basis of radiation biology: Taylor & Francis London; 1987
- Dilsiz, N., Sahaboglu, A., Yıldız, M.Z. and A. Reichenbach, Protective effects of various antioxidants during ischemia-reperfusion in the rat retina. Graefe's Archive for Clinical and Experimental Ophthalmology, 244(5), (2006) 627-633.
- Pacifico, S., D’Abrosca, B., Scognamiglio, M., D’Angelo, G., Gallicchio, M., Galasso, S., Monaco, P. and A. Fiorentino, NMR-based metabolic profiling and in vitro antioxidant and hepatotoxic assessment of partially purified fractions from Golden germander (Teucrium polium L.) methanolic extract. Food chemistry, 135(3), (2012) 1957-1967.
- Nematollahi-Mahani, S., Rezazadeh-Kermani, M., Mehrabani, M. and N. Nakhaee, Cytotoxic effects of Teucrium polium. On some established cell lines. Pharmaceutical biology, 45(4), (20007) 295-298.
- Polat, T., Özer, H., Öztürk, E., Çakir, A., Kandemir, A. and Y. Demir, Chemical Composition of the Essential Oil of Teucrium multicaule Montbret Et Aucher Ex Bentham from Turkey. Journal of Essential Oil Research, 22(5), (2010) 443-445.
ANTIMUTAGENIC AND ANTIOXIDANT ACTIVITIES OF TEUCRIUM MULTICAULE AND ITS CYTOTOXIC EFFECT ON MURINE LR7 CELL
Öz
In present study, DNA
protection, antioxidant and cytotoxic effects of Teucrium multicaule
Montbret Et Aucher Ex Bentham methanol extract (TME) was investigated.
Cytotoxic effects and antioxidant activities of TME was determined by MTT and
DPPH scavenging and DNA protection methods. As a result, high dose of TME
exhibited a cytotoxic effect on murine L cells. Although, TME also showed a
strong antimutagenic activity in DNA protection test system, it exhibited
modest activity in DPPH test system. Consequently, it may be used as natural
agent for antioxidant and antimutagenic properties.
Anahtar Kelimeler
Cytotoxicity DNA protection Antioxidant Antimutagenic Teucrium multicaule
Kaynakça
- Mohammed, F.S., Sevindik, M., Bal, C. and Z. Selamoglu, Biological Activities of Adiantum capillus-veneris Collected From Duhok Province (Iraq). Communications Faculty of Sciences University of Ankara Series C Biology, 28(2), (2019) 128-142.
- Mohammed, F.S., Karakaş, M., Akgül, H. and M. Sevindik, Medicinal Properties of Allium calocephalum Collected from Gara Mountain (Iraq). Fresen Environ Bull, 28(10), (2019) 7419-7426.
- Sevindik, M., Akgul, H., Pehlivan, M. and Z. Selamoglu, Determination of therapeutic potential of Mentha longifolia ssp. longifolia. Fresen Environ Bull, 26(7), (2017) 4757-4763.
- Ekim, T., Teucrium L. In: Davis PH, editor. Flora of Turkey and the East Aegean Islands, Vol. 7. Edinburgh, UK: Edinburgh University Press, pp. 58. 1982.
- Cantino, P.D., Harley, R.M. and S.J. Wagstaff, Genera of Labiatae: status and classification. In: Harley RM, Reynolds T, editors. Advances in Labiate Science. Kew, UK: Royal Botanic Gardens, pp. 511–522. 1992.
- Navarro, T. and J. El Oualidi, Trichome morphology in Teucrium L. (Labiatae). A taxonomic review. Anales Jardin Botanico De Madrid, 57, (2000) 277–297.
- Lakušić, B., Stevanović, B., Jančić, R. and D. Lakušić, Habitat-related adaptations in morphology and anatomy of Teucrium (Lamiaceae) species from the Balkan peninsula (Serbia and Montenegro). Flora-Morphology, Distribution, Functional Ecology of Plants, 205(10), (2010) 633-646.
- El Atki, Y., Aouam, I., El Kamari, F., Taroq, A., Lyoussi, B., Oumokhtar, B. and A. Abdellaoui, Phytochemistry, antioxidant and antibacterial activities of two Moroccan Teucrium polium L. subspecies: Preventive approach against nosocomial infections. Arabian Journal of Chemistry, (2019) https://doi.org/10.1016/j.arabjc.2019.04.001
- Elmasri, W.A., Hegazy, M.E.F., Mechref, Y. and P.W. Paré, Structure-antioxidant and anti-tumor activity of Teucrium polium phytochemicals. Phytochemistry letters, 15, (2016) 81-87.
- Aksoy Sagirli, P., Ozsoy, N., Ecevit-Genc, G. and G. Melikoglu, In vitro antioxidant activity, cyclooxygenase-2, thioredoxin reductase inhibition and DNA protection properties of Teucrium sandrasicum L. Industrial Crops and Products, 74, (2015) 545-550.
- Yalcin, A., Yumrutas, O., Kuloglu, T., Elibol, E., Parlar, A., Yilmaz, İ., Pehlivan, M., Dogukan, M., Uckardes, F., Aydin, H., Turk, A., Uludag, O., Sahin, İ., Ugur, K. and S. Aydin, Hepatoprotective properties for Salvia cryptantha extract on carbon tetrachloride-induced liver injury. Cellular and molecular biology, 63(12), (2017) 56-62.
- Gaulejac, N.S., Provost, C. and N. Vivas, Comparative study of polyphenol scavenging activities assessed by different methods. Journal of Agricultural and food Chemistry, 47(2), (1999) 425-431.
- Lee, J.C., Kim, H.R., Kim, J. and Y.S. Jang, Antioxidant property of an ethanol extract of the stem of Opuntia ficus-indica var. saboten. Journal of agricultural and food chemistry, 50(22), (2002) 6490-6496.
- Sharififar, F., Dehghn-Nudeh, G. and M. Mirtajaldini, Major flavonoids with antioxidant activity from Teucrium polium L. Food Chemistry, 112(4), (2009) 885-888.
- Çakir, A., Mavi, A., Kazaz, C., Yildirim, A, Küfrevioğlu Öİ. Antioxidant activities of the extracts and components of Teucrium orientale L. var. orientale. Turkish Journal of Chemistry, 30(4), (2006) 483-494.
- von Sonntag, C., The chemical basis of radiation biology: Taylor & Francis London; 1987
- Dilsiz, N., Sahaboglu, A., Yıldız, M.Z. and A. Reichenbach, Protective effects of various antioxidants during ischemia-reperfusion in the rat retina. Graefe's Archive for Clinical and Experimental Ophthalmology, 244(5), (2006) 627-633.
- Pacifico, S., D’Abrosca, B., Scognamiglio, M., D’Angelo, G., Gallicchio, M., Galasso, S., Monaco, P. and A. Fiorentino, NMR-based metabolic profiling and in vitro antioxidant and hepatotoxic assessment of partially purified fractions from Golden germander (Teucrium polium L.) methanolic extract. Food chemistry, 135(3), (2012) 1957-1967.
- Nematollahi-Mahani, S., Rezazadeh-Kermani, M., Mehrabani, M. and N. Nakhaee, Cytotoxic effects of Teucrium polium. On some established cell lines. Pharmaceutical biology, 45(4), (20007) 295-298.
- Polat, T., Özer, H., Öztürk, E., Çakir, A., Kandemir, A. and Y. Demir, Chemical Composition of the Essential Oil of Teucrium multicaule Montbret Et Aucher Ex Bentham from Turkey. Journal of Essential Oil Research, 22(5), (2010) 443-445.
Toplam 20 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Yapısal Biyoloji |
| Bölüm | Research Article |
| Yazarlar | |
| Yayımlanma Tarihi | 30 Haziran 2020 |
| Kabul Tarihi | 10 Mart 2020 |
| Yayımlandığı Sayı | Yıl 2020 Cilt: 29 Sayı: 1 |
Communications Faculty of Sciences University of Ankara Series C-Biology.
This work is licensed under a Creative Commons Attribution 4.0 International License.