Olgu Sunumu
Yıl 2017,
Cilt: 31 Sayı: 3, 177 - 180, 17.12.2017
Öz
Liken skleroz, kadınlarda daha sık
görülen, otoimmun bozuklukların ve dermal değişikliklerin eşlik ettiği, kronik
enflamatuar, progressif bir hastalıktır.
Liken sklerozlu hastalarının % 85-98’in de anogenital tutulum
izlenir. Genital tutulumlu liken skleroz
uygun şekilde tedavi edilmez ise, özellikle premenarş ve postmenopozal dönemde
vulvada fonksiyonel ve yapısal bozukluklara neden olabilir. Bu makalede, 94
yaşında idrar yapmada güçlük, idrar yapamama yakınmalarıyla başvuran kadın hastada,
liken sklerozun vulvar tutulumuna bağlı gelişen, bir vulvar fimozis olgusunun
başarılı tıbbi tedavisi literatür eşliğinde sunuldu
Anahtar Kelimeler
Kaynakça
- Referans1 Mc Pherson T, Cooper S. Vulval lichen sclerosus and lichen planus. Dermatol Ther 2010;23:523.
- Referans2 Fistarol SK, Itin PH. Diagnosis and treatment of lichen sclerosus: an update. Am J Clin Dermatol 2013;14:27-47.
- Referans3 Tong LX, Sun GS, Teng JM. Pediatric Lichen Sclerosus: A Review of the Epidemiology and Treatment Options. Pediatr Dermatol 2015;32:593-9. doi: 10. 1111/pde.12615.
- Referans4 Virgili A, Borghi A, Giulia B, Toni G, Minghetti S, Corazza M. Prospective Clinical and Epidemiologic study of Vulvar Lichen Sclerosus: Analysis of Prevalence and Severity of Clinical Features, together with Historical and Demographic Associations. Dermatology 2014;228:145-151. doi: 10.1159/000356163.
- Referans5 Karadağ AS, Kavala M, Ozlu E, Zindancı İ, Özkanlı S, Türkoğlu Z, Zemheri E. The co-occurence of lichen sclerosus et atrophicus and celaic disease. Indian Dermatol Online J 2014;5:106-8.
- Referans6 Chan I, Liu L, Hamada T, Sethuraman G, Mc Grath JA. The molecular basis of lipoid proteinosis: mutations in extracellular matrix protein 1.Exp Dermatol 2007;16:881-90.
- Referans7 Higgins CA, Cruickshank ME. Apopulation-based case-control study of aetiological factors associated with vulval lichen sclerosus. J Obstet Gynaecol 2012;32:271.
- Referans8 Chi CC, Kirtschig G, Baldo M, et all. Systemic review and meta-analysis of randomized controlled trials on topical interventions for genital lichen sclerosus. J Am Acad Dermatol 2012;67:305.
- Referans9 Borghi A, Corazza M, Minghetti S, Toni G, Virgili A Continuous vs. tapering application of the potent topical corticosteroid mometasone furoate in the treatment of vulvar lichen sclerosus: results of a randomized trial. Br J Dermatol 2015;173:1381.
- Referans10 Kauppila S, Kotila V, Knuuti E, et al. The effect of topical pimecrolimus on inflammatory infiltrate in vulvar lichen sclerosus. Am J Obstet Gynecol 2010;202:181.e1.
- Referans11 Sotiriou E, Panagiotidou D, Ioannidis D. An open trial of 5-aminolevulinic acid photodynamic therapy for vulvar lichen sclerosus. Eur J Obstet Gynecol Reprod Biol 2008;141:187.
- Referans12 Bülbül BE, Turan H, Tunalı S, et al. Open-label trial of cyclosporine for vulvar lichen sclerosus. J Am Acad Dermatol 2007;57:276.
- Referans13 Nayeemuddin F, Yates VM. Lichen sclerosus et atrophicus responding to methotrexate. Clin Exp Dermatol 2008;33:651.
- Referans14 Rouzier R, Haddad B, Deyrolle C, Pelisse M, Moyal-Barracco M, Paniel BJ. Perinoplasty fort he teratment of introital stenosis related to vulvar lichen sclerosus. Am J Obstet Gynecol 2002;186:49-52.
- Referans15 Flynn AN, King M, RieffM, Krapf J, Goldstein AT. Patient Satisfaction of Surgical Treatment of Clitoral Phimosis and Labial Adhesions Caused by Lichen Sclerosus. Sex Med 2015;3:251-255.
- Referans16 Lee A, Bradford J, Fischer G. Long-term Management of Adult Vulvar Lichen Sclerosus: A prospective Cohort Study of 507 Women. JAMA Dermatol 2015;151:1061.
- Referans17 Rotondo JC, Borghi A, Selvatici R, et al. Hypermethylation-Induced Inactivation of the IRF6 Gene as a Possible Early Event in Progression of Vulvar Squamous Cell Carcinoma Associated With Lichen Sclerosus. JAMA Dermatol 2016;152:928.
Toplam 17 adet kaynakça vardır.
Ayrıntılar
| Bölüm | Makaleler |
|---|---|
| Yazarlar | |
| Yayımlanma Tarihi | 17 Aralık 2017 |
| Gönderilme Tarihi | 20 Şubat 2017 |
| Yayımlandığı Sayı | Yıl 2017 Cilt: 31 Sayı: 3 |
