Araştırma Makalesi
BibTex RIS Kaynak Göster

The importance of clinical and pathological features in bladder cancer and its effects on disease course

Yıl 2019, Cilt: 46 Sayı: 4, 821 - 829, 15.12.2019
https://doi.org/10.5798/dicletip.661400

Öz

Objective: Bladder cancer (BC) is the most common malignancy of the urinary system and the incidence of BC varies
regionally. Bladder cancer is more common in men than in women. Tumor stage and grade are the most important
prognostic factors of BC. We aimed to describe the patterns of BC presentation and to examine the differences in the
distribution of prognostic factors by gender, age, tumor size, and involvement region.
Method: The patients diagnosed with BC (non-muscle invasive or muscle-invasive BC) were included. Intravesical
treatment, tumor diameter, pathological grade, tumor involved area and tumor stage were recorded as variables. The
survival rates of the patients were calculated for diverse clinical and pathological findings.
Results:In a total of 124 patients, 23 (18.5%) of patients were female and 101(81.5%) of patients were male, the
median age of all patients was 64 (IQR: 21-92). There were 36 % (41) patients in early-stage (stage 0 or stage insitu),
50.9 % (58) patients in stage 1, 7% (8) patients in stage 2, 4.4 %(5) patients in stage 3 and 1.8% (2) patients were in
stage 4. There were significantly different OS rates of patients with BC in different stages (p<0.001). Tumor diameter
in 36 of patients was < 2.5cm (group 1) and tumor diameter in 28 patients was>2.5cm (group 2). There was a
significant difference between the overall survival rates of group 1 and group 2(p=0.02). There were 55 patients with
low-grade BC and 38 of patients with high-grade BC, and the difference between their survival rates was statistically
significant (p=0.001).
Conclusions: Tumor stage, tumor diameter, and grade were demonstrated and confirmed as the crucial prognostic
factors of bladder cancer. Additionally, lateral walls of bladder constitute the most commonly involved area, but their
roles in the disease course still remain unclear.

Kaynakça

  • 1. Ploeg M, Aben KK, KiemeneyLA.The present and future burden of urinary bladder cancer in the world. World J Urol. 2009;27:289-293.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Original Articles
Yazarlar

Sahin Lacin Bu kişi benim 0000-0002-1160-0437

Nilgun Sogutcu 0000-0002-2455-2964

Yayımlanma Tarihi 15 Aralık 2019
Gönderilme Tarihi 7 Ekim 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 46 Sayı: 4

Kaynak Göster

APA Lacin, S., & Sogutcu, N. (2019). The importance of clinical and pathological features in bladder cancer and its effects on disease course. Dicle Tıp Dergisi, 46(4), 821-829. https://doi.org/10.5798/dicletip.661400
AMA Lacin S, Sogutcu N. The importance of clinical and pathological features in bladder cancer and its effects on disease course. diclemedj. Aralık 2019;46(4):821-829. doi:10.5798/dicletip.661400
Chicago Lacin, Sahin, ve Nilgun Sogutcu. “The Importance of Clinical and Pathological Features in Bladder Cancer and Its Effects on Disease Course”. Dicle Tıp Dergisi 46, sy. 4 (Aralık 2019): 821-29. https://doi.org/10.5798/dicletip.661400.
EndNote Lacin S, Sogutcu N (01 Aralık 2019) The importance of clinical and pathological features in bladder cancer and its effects on disease course. Dicle Tıp Dergisi 46 4 821–829.
IEEE S. Lacin ve N. Sogutcu, “The importance of clinical and pathological features in bladder cancer and its effects on disease course”, diclemedj, c. 46, sy. 4, ss. 821–829, 2019, doi: 10.5798/dicletip.661400.
ISNAD Lacin, Sahin - Sogutcu, Nilgun. “The Importance of Clinical and Pathological Features in Bladder Cancer and Its Effects on Disease Course”. Dicle Tıp Dergisi 46/4 (Aralık 2019), 821-829. https://doi.org/10.5798/dicletip.661400.
JAMA Lacin S, Sogutcu N. The importance of clinical and pathological features in bladder cancer and its effects on disease course. diclemedj. 2019;46:821–829.
MLA Lacin, Sahin ve Nilgun Sogutcu. “The Importance of Clinical and Pathological Features in Bladder Cancer and Its Effects on Disease Course”. Dicle Tıp Dergisi, c. 46, sy. 4, 2019, ss. 821-9, doi:10.5798/dicletip.661400.
Vancouver Lacin S, Sogutcu N. The importance of clinical and pathological features in bladder cancer and its effects on disease course. diclemedj. 2019;46(4):821-9.