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A Rare Cause of Breast Mass: Granular Cell Tumor

Yıl 2019, Cilt: 21 Sayı: 2, 142 - 144, 30.08.2019
https://doi.org/10.18678/dtfd.538404

Öz

Granular cell tumor is a rare type of soft tissue tumor originated from Schwann cells and often affecting head and neck region. Granular cell tumor, which may have many different organ involvements in the body, can rarely observed in breast tissue. A 57-year-old postmenopausal woman underwent excisional biopsy in another health facility due to a palpable rapidly growing painless mass on her left breast. Re-excision with wide surgical margins was performed to the patient whose biopsy was reported as granular cell tumor of breast with positive surgical margin. Postoperative follow-up was uneventful, and the patient was discharged without complication. Wide local excision should be performed to prevent local recurrence in the surgical treatment of granular cell breast tumor, which is similar to breast carcinoma in both radiological and clinic appearance. In this case report, we aimed to present diagnosis and treatment of granular cell tumor with current literature knowledge.

Kaynakça

  • Abrikossoff AI. Weitere untersuchungen über myoblastenmyome [Further investigations on myoblastomas]. Virchows Arch Pathol Anat Physiol Klin Med. 1931;280(3):723-40.
  • Ordóñez NG, Mackay B. Granular cell tumor: a review of the pathology and histogenesis. Ultrastruct Pathol. 1999;23(4):207-22.
  • Fujiwara K, Maeda I, Mimura H. Granular cell tumor of the breast mimicking malignancy: a case report with a literature review. Acta Radiol Open. 2018;7(12):2058460118816537.
  • Pergel A, Yucel AF, Karaca AS, Aydin I, Sahin DA, Demirbag N. A therapeutic and diagnostic dilemma: granular cell tumor of the breast. Case Rep Med. 2011;2011:972168.
  • Castillo Lara M, Martínez Herrera A, Torrejón Cardoso R, Lubián López DM. Granular cell tumor in breast: a case report. Breast Cancer (Dove Med Press). 2017;9:245-8.
  • Hoess C, Freitag K, Kolben M, Allgayer B, Laemmer-Skarke I, Nathrath WB, et al. FDG PET evaluation of granular cell tumor of the breast. J Nucl Med. 1998;39(8):1398-401.
  • Jiménez-Herrero E, Hervás-Marín D, Vera-Sempere FJ. Expresión de calretinina en el tumor de células granulares: análisis del gradiente de intensidad en la inmunotinción con correlación clínico-patológica [Calretinin expression in the granular cell tumor: an analysis of the immunostaining intensity gradient and its clinicopathological correlation]. Rev Esp Patol. 2014;47(3):149-155.
  • Kondi-Pafiti A, Kairi-Vassilatou E, Liapis A, Bakalianou K, Iavazzo Ch, Hasiakos D. Granular cell tumor of the female genital system: clinical and pathologic characteristics of five cases and literature review. Eur J Gynaecol Oncol. 2010;31(2): 222-4.
  • Nasser H, Ahmed Y, Szpunar SM, Kowalski PJ. Malignant granular cell tumor: a look into the diagnostic criteria. Pathol Res Pract. 2011;207(3):164-8.
  • Brown AC, Audisio RA, Regitnig P. Granular cell tumour of the breast. Surg Oncol. 2011;20(2):97-105.

Memede Kitlenin Nadir Bir Nedeni: Granüler Hücreli Tümör

Yıl 2019, Cilt: 21 Sayı: 2, 142 - 144, 30.08.2019
https://doi.org/10.18678/dtfd.538404

Öz

Granüler hücreli tümör sıklıkla baş ve boyun bölgesini etkileyen, Schwann hücrelerinden kaynaklanan, nadir bir yumuşak doku tümörü tipidir. Vücutta pek çok farklı organ tutulumu olabilen granüler hücreli tümör, nadir de olsa memede de gözlenebilmektedir. Elli yedi yaşında postmenopozal kadın hastaya sol memede hızlı büyüyen ele gelen ağrısız palpabl kitle nedeniyle dış merkezde eksizyonel biyopsi uygulanmıştı. Biyopsisi memenin granüler hücreli tümörü olarak raporlanan ve cerrahi sınır pozitifliği olan hastaya, geniş sağlam cerrahi sınırlarla reeksizyon yapıldı. Postoperatif takiplerinde bir problem yaşanmayan hasta sorunsuz bir şekilde taburcu edildi. Klinik ve radyolojik olarak meme karsinomuna benzerlik gösteren granüler hücreli meme tümörünün cerrahi tedavisinde lokal nüksü engellemek amacıyla geniş lokal eksizyon yapılmalıdır. Bu olgu sunumunda, granüler hücreli tümörün tanı ve tedavisini güncel literatür bilgisi eşliğinde sunmayı amaçladık.

Kaynakça

  • Abrikossoff AI. Weitere untersuchungen über myoblastenmyome [Further investigations on myoblastomas]. Virchows Arch Pathol Anat Physiol Klin Med. 1931;280(3):723-40.
  • Ordóñez NG, Mackay B. Granular cell tumor: a review of the pathology and histogenesis. Ultrastruct Pathol. 1999;23(4):207-22.
  • Fujiwara K, Maeda I, Mimura H. Granular cell tumor of the breast mimicking malignancy: a case report with a literature review. Acta Radiol Open. 2018;7(12):2058460118816537.
  • Pergel A, Yucel AF, Karaca AS, Aydin I, Sahin DA, Demirbag N. A therapeutic and diagnostic dilemma: granular cell tumor of the breast. Case Rep Med. 2011;2011:972168.
  • Castillo Lara M, Martínez Herrera A, Torrejón Cardoso R, Lubián López DM. Granular cell tumor in breast: a case report. Breast Cancer (Dove Med Press). 2017;9:245-8.
  • Hoess C, Freitag K, Kolben M, Allgayer B, Laemmer-Skarke I, Nathrath WB, et al. FDG PET evaluation of granular cell tumor of the breast. J Nucl Med. 1998;39(8):1398-401.
  • Jiménez-Herrero E, Hervás-Marín D, Vera-Sempere FJ. Expresión de calretinina en el tumor de células granulares: análisis del gradiente de intensidad en la inmunotinción con correlación clínico-patológica [Calretinin expression in the granular cell tumor: an analysis of the immunostaining intensity gradient and its clinicopathological correlation]. Rev Esp Patol. 2014;47(3):149-155.
  • Kondi-Pafiti A, Kairi-Vassilatou E, Liapis A, Bakalianou K, Iavazzo Ch, Hasiakos D. Granular cell tumor of the female genital system: clinical and pathologic characteristics of five cases and literature review. Eur J Gynaecol Oncol. 2010;31(2): 222-4.
  • Nasser H, Ahmed Y, Szpunar SM, Kowalski PJ. Malignant granular cell tumor: a look into the diagnostic criteria. Pathol Res Pract. 2011;207(3):164-8.
  • Brown AC, Audisio RA, Regitnig P. Granular cell tumour of the breast. Surg Oncol. 2011;20(2):97-105.
Toplam 10 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Olgu Sunumu
Yazarlar

Semra Demirli Atıcı 0000-0002-8287-067X

Semra Salimoğlu Bu kişi benim 0000-0002-9849-244X

Buğra Sağlam Bu kişi benim 0000-0002-6025-9570

Gülen Gül 0000-0001-5750-0098

Cengiz Aydın 0000-0003-4713-2871

Yayımlanma Tarihi 30 Ağustos 2019
Gönderilme Tarihi 11 Mart 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 21 Sayı: 2

Kaynak Göster

APA Demirli Atıcı, S., Salimoğlu, S., Sağlam, B., Gül, G., vd. (2019). A Rare Cause of Breast Mass: Granular Cell Tumor. Duzce Medical Journal, 21(2), 142-144. https://doi.org/10.18678/dtfd.538404
AMA Demirli Atıcı S, Salimoğlu S, Sağlam B, Gül G, Aydın C. A Rare Cause of Breast Mass: Granular Cell Tumor. Duzce Med J. Ağustos 2019;21(2):142-144. doi:10.18678/dtfd.538404
Chicago Demirli Atıcı, Semra, Semra Salimoğlu, Buğra Sağlam, Gülen Gül, ve Cengiz Aydın. “A Rare Cause of Breast Mass: Granular Cell Tumor”. Duzce Medical Journal 21, sy. 2 (Ağustos 2019): 142-44. https://doi.org/10.18678/dtfd.538404.
EndNote Demirli Atıcı S, Salimoğlu S, Sağlam B, Gül G, Aydın C (01 Ağustos 2019) A Rare Cause of Breast Mass: Granular Cell Tumor. Duzce Medical Journal 21 2 142–144.
IEEE S. Demirli Atıcı, S. Salimoğlu, B. Sağlam, G. Gül, ve C. Aydın, “A Rare Cause of Breast Mass: Granular Cell Tumor”, Duzce Med J, c. 21, sy. 2, ss. 142–144, 2019, doi: 10.18678/dtfd.538404.
ISNAD Demirli Atıcı, Semra vd. “A Rare Cause of Breast Mass: Granular Cell Tumor”. Duzce Medical Journal 21/2 (Ağustos 2019), 142-144. https://doi.org/10.18678/dtfd.538404.
JAMA Demirli Atıcı S, Salimoğlu S, Sağlam B, Gül G, Aydın C. A Rare Cause of Breast Mass: Granular Cell Tumor. Duzce Med J. 2019;21:142–144.
MLA Demirli Atıcı, Semra vd. “A Rare Cause of Breast Mass: Granular Cell Tumor”. Duzce Medical Journal, c. 21, sy. 2, 2019, ss. 142-4, doi:10.18678/dtfd.538404.
Vancouver Demirli Atıcı S, Salimoğlu S, Sağlam B, Gül G, Aydın C. A Rare Cause of Breast Mass: Granular Cell Tumor. Duzce Med J. 2019;21(2):142-4.
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