Öz
"Burned-out testicular tumour" is extremely
rare. Burned-out phenomenon describes partially or completely regressed germ
cell tumours of the testes diagnosed after metastases in several parts of the
body; including the mediastinum, cervical and axillary lymph nodes,
retroperitoneal lymph nodes, and the retroperitoneal region. Physical
examination of the testicles reveals non-specific findings. A 31-year-old male
presented with abdominal and back pain. The physical examination findings were unremarkable.
Imaging with computerized tomography showed a retroperitoneal mass. Excision of
the retroperitoneal mass and the paraaortic, paracaval, and retroperitoneal
lymph nodes was performed. The postoperative period was uneventfuland he was
discharged on the postoperative 5thday. The postoperative
pathological examination of the specimen reported a metastatic seminoma. Investigation
of the underlying cause of a retroperitoneal mass in young adults requires
including metastasis of burned-out germ cell tumours in the differential
diagnosis. Further case reports on this rare type of tumour are required so
that all potential risk factors will be defined and treatment protocols will be
updated to optimize the management of the patients with burned-out germ cell
tumours.
Anahtar Kelimeler
burned-out retroperitoneal mass lymph node dissection orchiectomy
Kaynakça
- 1. Albany C, Einhorn LH. Extragonadal germ cell tumors: clinical presentation and management.
- CurrOpin Oncol 2013;25:261-265
- 2. Tasu JP, Faye N, Eschwege P, Rocher L, BléryM.,Imaging of burned-out testis tumor: five new cases and review of the literature. J Ultrasound Med 2003;22:515-521.
- 3. Lehmann D, Muller H. Analysis of the autoimmune response in an ‘in situ’ carcinoma of the testis. Int J Androl 1987;10:163-168.
- 4. Curigliano G, Magni E, Renne G, De Cobelli O, Rescigno M, Torrisi R, et al. “Burned out” phenomenon of the testis in retroperitoneal seminoma. Acta Oncol 2006;45:335-336
- 5. Ojea Calvo A, Rodríguez Alonso A, Pérez García D, Domínguez Freire F, Alonso Rodrigo A, Rodríguez Iglesias B, et al. Tumor extragonadal de célulasgerminales con fénomeno“burned-out” entestí- culo. ActasUrolEsp, 1999; 23(10):880-884.
- 6. Setchell BP. The functional significance of the blood-testis barrier. J Androl 1980;1:3-11
- 7. Scholz M, Zehender M, Thalmann GN, Borner M, Thoni H, Studer UE., Extragonadal retroperitoneal germ cell tumor: evidence of origin in the testis. Ann Oncol 2002;13:121-124
- 8. Simmonds PD, Mead GM, Lee AH, Theaker JM, Dewbury K, Smart CJ , Orchiectomy after chemotherapy in patients with metastatic testicular cancer. Is it indicated? Cancer 1995;75:1018-1024.
- 9. Fuchs E, Hatch T, Seifert A. Extragonadal germ cell tumor: the preoperative urological evaluation. J Urol 1987;137:993-995.
- 10. Medini E, Levitt SH, Jones TK, Y. Rao, The management of extratesticularseminoma without gonadal involvement. Cancer 1979;44:2032-2038
Öz
"Burned-out testis tümörü" nadir görülen bir
tümör türüdür. Burned out fenomeni, testisteki germ hücreli tümörün parsiyel ya
da tamamen regrese olup, mediastinel, servikal, aksiller, retroperitoneal lenf
nodları veya retroperitonal bölgeye metastaz ile bulgu vermesi olarak
tanımlanır. Yapılan fizik muayenede testis muayenesi olağandır. 31 yaşında
erkek hasta sırt ve karın ağrısı yakınması ile başvurdu. Yapılan fizik
muayenesinde patolojik bulguya rastlanılmadı. Çekilen abdomen tomografide
retroperitoneal kitle saptandı. Retroperitonela kitle eksizyonu, paraaortik,
parakaval ve retroperitoneal lenf nodu diseksiyonu uygulandı. Hastanın
postoperatif dönemi komplikasyonsuz olup, postoperatif beşinci gün taburcu edilmiştir.
Patoloji sonucu, seminom metastazı olarak raporlanmıştır. Retroperitoneal
kitle ile karşımıza çıkan genç hastalarda burned out tümörlerin metastazları
olabileceği akılda tutulmalıdır.
Burned-out tümörlerin tedavi seçenekleri zamanla
değişebilir. Farklı risk faktörlerini tanımlamak ve tedavinin optimize
edilmesine yardımcı olabilmek için daha geniş olgu serileri yayınlanmalıdır.
Anahtar Kelimeler
burned-out retroperitoneal kitle lenf nodu diseksiyonu orşiektomi
Kaynakça
- 1. Albany C, Einhorn LH. Extragonadal germ cell tumors: clinical presentation and management.
- CurrOpin Oncol 2013;25:261-265
- 2. Tasu JP, Faye N, Eschwege P, Rocher L, BléryM.,Imaging of burned-out testis tumor: five new cases and review of the literature. J Ultrasound Med 2003;22:515-521.
- 3. Lehmann D, Muller H. Analysis of the autoimmune response in an ‘in situ’ carcinoma of the testis. Int J Androl 1987;10:163-168.
- 4. Curigliano G, Magni E, Renne G, De Cobelli O, Rescigno M, Torrisi R, et al. “Burned out” phenomenon of the testis in retroperitoneal seminoma. Acta Oncol 2006;45:335-336
- 5. Ojea Calvo A, Rodríguez Alonso A, Pérez García D, Domínguez Freire F, Alonso Rodrigo A, Rodríguez Iglesias B, et al. Tumor extragonadal de célulasgerminales con fénomeno“burned-out” entestí- culo. ActasUrolEsp, 1999; 23(10):880-884.
- 6. Setchell BP. The functional significance of the blood-testis barrier. J Androl 1980;1:3-11
- 7. Scholz M, Zehender M, Thalmann GN, Borner M, Thoni H, Studer UE., Extragonadal retroperitoneal germ cell tumor: evidence of origin in the testis. Ann Oncol 2002;13:121-124
- 8. Simmonds PD, Mead GM, Lee AH, Theaker JM, Dewbury K, Smart CJ , Orchiectomy after chemotherapy in patients with metastatic testicular cancer. Is it indicated? Cancer 1995;75:1018-1024.
- 9. Fuchs E, Hatch T, Seifert A. Extragonadal germ cell tumor: the preoperative urological evaluation. J Urol 1987;137:993-995.
- 10. Medini E, Levitt SH, Jones TK, Y. Rao, The management of extratesticularseminoma without gonadal involvement. Cancer 1979;44:2032-2038
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Cerrahi |
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 3 Ağustos 2019 |
| Kabul Tarihi | 23 Nisan 2019 |
| Yayımlandığı Sayı | Yıl 2019 Cilt: 2 Sayı: 2 |
