Araştırma Makalesi
Yıl 2022,
Cilt: 8 Sayı: 5, 636 - 641, 04.09.2022
Öz
Kaynakça
- 1. Say L, Chou D, Gemmill A, Tunçalp Ö, Moller AB, Daniels J, et al. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health 2014;2:e323-33.
- 2. Tranquilli AL, Dekker G, Magee L, Roberts J, Sibai SM, Steyn W, et al. The classification, diagnosis and management of the hypertensive disorders of pregnancy: a revised statement from the ISSHP. Pregnancy Hypertens 2014;4:97-104.
- 3. Roberts JM, Hubel CA. The two stage model of preeclampsia: variations on the theme. Placenta 2009;30(Suppl A):S32-7.
- 4. Azpurua H, Dulay AT, Buhimschi IA, Bahtiyar MO, Funai E, Abdel-Razeq SS, et al. Fetal renal artery impedance as assessed by Doppler ultrasound in pregnancies complicated by intraam- niotic inflammation and preterm birth. Am J Obstet Gynecol 2009;200:203.e1-11.
- 5. Bellamy L, Casas JP, Hingorani AD, Williams DJ. Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ 2007;335:974.
- 6. Vikse BE. Pre-eclampsia and the risk of kidney disease. Lancet 2013;382:104-6.
- 7. Walton SL, Bielefeldt-Ohmann H, Singh RR, Li J, Paravicini TM, Little MH, et al. Prenatal hypoxia leads to hypertension, renal renin-angiotensin system activation and exacerbates salt-induced pathology in a sex-specific manner. Sci Rep 2017;7:8241.
- 8. Stojanovska V, Scherjon SA, Plösch T. Preeclampsia as modulator of offspring health. Biol Reprod 2016;94:53.
- 9. Ahmadi M, Ganji J, Zamanfar D, Ghobadi Golafshani P. Investigation of the relationship between exposure to preeclampsia and overweight/obesity in 2-7 year old children. Int J Womens Health Reprod Sci 2020;8:290-6.
- 10. Paauw ND, van Rijn BB, Lely AT, Joles JA. Pregnancy as a critical window for blood pressure regulation in mother and child: programming and reprogramming. Acta Physiol 2017;219:241-59.
- 11. Tang J, Zhu Z, Xia S, Li N, Chen N, Gao Q, et al. Chronic hypoxia in pregnancy affected vascular tone of renal interlobar arteries in the offspring. Sci Rep 2015;5:9723.
- 12. Nicolaides K, Giuseppe R, Hecher K, Ximenes R. Doppler in Obstetrics. ISUOG Educational Series, The Fetal Medicine Foundation, 2022.
- 13. Sulemanji M, Vakili K. Neonatal renal physiology. Semin Pediatr Surg 2013;22:195-8.
- 14. Boubred F, Grandvuillemin I, Simeoni U. Pathophysiology of fetal and neonatal kidneys. In: Buonocore G, Bracci R, Weindling M, eds. Neonatology: A Practical Approach to Neonatal Diseases. Milano: Springer; 2012:pp.1018-26.
- 15. Brosens I, Pijnenborg R, Vercruysse L, Romero R. The “Great Obstetrical Syndromes” are associated with disorders of deep placentation. Am J Obstet Gynecol 2011;204:193-201.
- 16. Ness RB, Sibai BM. Shared and disparate components of the pathophysiologies of fetal growth restriction and preeclampsia. Am J Obstet Gynecol 2006;195:40-9.
- 17. Sohn C, Fendel H. [The renal artery and uterine circulation in normal and toxemic pregnancies]. Z Geburtshilfe Perinatol 1988;192:43-8. [Article in German]
- 18. Yura T, Yuasa S, Sumikura T, Takahashi N, Aono M, Kunimune Y, et al. Doppler sonographic measurement of phasic renal artery blood flow velocity in patients with chronic glomerulonephritis. J Ultrasound Med 1993;4:215-9.
- 19. Kaya S, Kaya B: Evaluation of fetal renal artery Doppler indices in pregnancies complicated with preeclampsia. Gynecol Obstet Invest 2021;86:502-8.
- 20. Afsari E, Abbasalizadeh F, Fardiazar Z, Shahali S, Ahmadi YS. Is there a relationship between the severity of preeclampsia and fetal renal Doppler indices. Int J Women's Health Reprod Sci 2021;9:263-7.
- 21. Ma’ayeh M, Krishnan V, Gee SE, Russo J, Shellhaas C, Rood KM. Fetal renal artery impedance in pregnancies affected by preeclampsia. J Perinat Med 2020;48:313-6.
- 22. Ding H, Ding Z, Zaho M, Ji B, Lei J, Chen J, et al. Correlation of amniotic fluid index and placental aquaporin 1 levels in terms of preeclampsia. Placenta 2022;117:169-78.
- 23. Arduini D, Rizzo G. Normal values of pulsatility index from fetal vessels: a cross-sectional study on 1556 healthy fetuses. J Perinat Med 1990;18:165-72.
- 24. Vyas S, Nicolaides KH, Campbell S. Renal artery flow-velocity waveforms in normal and hypoxemic fetuses. Am J Obstet Gynecol 1989;161:168-72.
- 25. Platt JF, Ellis JH, Rubin JM, DiPietro MA, Sedman AB. Intrarenal arterial Doppler sonography in patients with nonobstructive renal disease: correlation of resistive index with biopsy findings. Am J Roentgen 1990;154:1223-7.
Yıl 2022,
Cilt: 8 Sayı: 5, 636 - 641, 04.09.2022
Öz
Objectives: Preeclampsia (PE), which affecting multi-organ systems, is one of the most common causes of feto-maternal morbidity and mortality. The fetal kidney is one of the vulnerable organs in PE caused by sustained vasospasm of the renal arteries. In this study, it was aimed to reveal the changes in the renal vascular bed with renal artery Doppler examinations in fetuses of pregnant women with PE.
Methods: Fifty-five pregnant women with PE and 60 healthy pregnant women were included in this prospective study. Multiple pregnancies, those who did not want to participate in the study, and those with other co-morbidities were excluded from the study. Fetal renal artery Doppler studies included renal artery systolic/diastolic (S/D) ratio, pulsatility index (PI) and resistance index (RI) of the control and PE groups, and findings such as week of birth and birth weight were recorded and analyzed statistically.
Results: Fetal renal artery PI values were found to be higher in pregnant women with PE compared to the control group (2.93 in the patient group, 2.28 in the control group, p < 0.001). There was no significant difference between RI values and S/D ratios between the two groups. In the preeclampsia group, gestational week and baby weight at birth were significantly lower.
Conclusions: Due to preeclampsia, hypoxia occurs in peripheral tissues and organs at the maternal level. Fetal organs are also affected by these hypoxic conditions. Doppler is an extremely useful examination tool in the evaluation of the status of peripheral organs such as the kidney. This study suggests that PE increases the resistance of renal arteries in fetuses of mothers with PE compared to fetuses of mothers without PE, which may contribute critically to kidney disease later in life.
Anahtar Kelimeler
Kaynakça
- 1. Say L, Chou D, Gemmill A, Tunçalp Ö, Moller AB, Daniels J, et al. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health 2014;2:e323-33.
- 2. Tranquilli AL, Dekker G, Magee L, Roberts J, Sibai SM, Steyn W, et al. The classification, diagnosis and management of the hypertensive disorders of pregnancy: a revised statement from the ISSHP. Pregnancy Hypertens 2014;4:97-104.
- 3. Roberts JM, Hubel CA. The two stage model of preeclampsia: variations on the theme. Placenta 2009;30(Suppl A):S32-7.
- 4. Azpurua H, Dulay AT, Buhimschi IA, Bahtiyar MO, Funai E, Abdel-Razeq SS, et al. Fetal renal artery impedance as assessed by Doppler ultrasound in pregnancies complicated by intraam- niotic inflammation and preterm birth. Am J Obstet Gynecol 2009;200:203.e1-11.
- 5. Bellamy L, Casas JP, Hingorani AD, Williams DJ. Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ 2007;335:974.
- 6. Vikse BE. Pre-eclampsia and the risk of kidney disease. Lancet 2013;382:104-6.
- 7. Walton SL, Bielefeldt-Ohmann H, Singh RR, Li J, Paravicini TM, Little MH, et al. Prenatal hypoxia leads to hypertension, renal renin-angiotensin system activation and exacerbates salt-induced pathology in a sex-specific manner. Sci Rep 2017;7:8241.
- 8. Stojanovska V, Scherjon SA, Plösch T. Preeclampsia as modulator of offspring health. Biol Reprod 2016;94:53.
- 9. Ahmadi M, Ganji J, Zamanfar D, Ghobadi Golafshani P. Investigation of the relationship between exposure to preeclampsia and overweight/obesity in 2-7 year old children. Int J Womens Health Reprod Sci 2020;8:290-6.
- 10. Paauw ND, van Rijn BB, Lely AT, Joles JA. Pregnancy as a critical window for blood pressure regulation in mother and child: programming and reprogramming. Acta Physiol 2017;219:241-59.
- 11. Tang J, Zhu Z, Xia S, Li N, Chen N, Gao Q, et al. Chronic hypoxia in pregnancy affected vascular tone of renal interlobar arteries in the offspring. Sci Rep 2015;5:9723.
- 12. Nicolaides K, Giuseppe R, Hecher K, Ximenes R. Doppler in Obstetrics. ISUOG Educational Series, The Fetal Medicine Foundation, 2022.
- 13. Sulemanji M, Vakili K. Neonatal renal physiology. Semin Pediatr Surg 2013;22:195-8.
- 14. Boubred F, Grandvuillemin I, Simeoni U. Pathophysiology of fetal and neonatal kidneys. In: Buonocore G, Bracci R, Weindling M, eds. Neonatology: A Practical Approach to Neonatal Diseases. Milano: Springer; 2012:pp.1018-26.
- 15. Brosens I, Pijnenborg R, Vercruysse L, Romero R. The “Great Obstetrical Syndromes” are associated with disorders of deep placentation. Am J Obstet Gynecol 2011;204:193-201.
- 16. Ness RB, Sibai BM. Shared and disparate components of the pathophysiologies of fetal growth restriction and preeclampsia. Am J Obstet Gynecol 2006;195:40-9.
- 17. Sohn C, Fendel H. [The renal artery and uterine circulation in normal and toxemic pregnancies]. Z Geburtshilfe Perinatol 1988;192:43-8. [Article in German]
- 18. Yura T, Yuasa S, Sumikura T, Takahashi N, Aono M, Kunimune Y, et al. Doppler sonographic measurement of phasic renal artery blood flow velocity in patients with chronic glomerulonephritis. J Ultrasound Med 1993;4:215-9.
- 19. Kaya S, Kaya B: Evaluation of fetal renal artery Doppler indices in pregnancies complicated with preeclampsia. Gynecol Obstet Invest 2021;86:502-8.
- 20. Afsari E, Abbasalizadeh F, Fardiazar Z, Shahali S, Ahmadi YS. Is there a relationship between the severity of preeclampsia and fetal renal Doppler indices. Int J Women's Health Reprod Sci 2021;9:263-7.
- 21. Ma’ayeh M, Krishnan V, Gee SE, Russo J, Shellhaas C, Rood KM. Fetal renal artery impedance in pregnancies affected by preeclampsia. J Perinat Med 2020;48:313-6.
- 22. Ding H, Ding Z, Zaho M, Ji B, Lei J, Chen J, et al. Correlation of amniotic fluid index and placental aquaporin 1 levels in terms of preeclampsia. Placenta 2022;117:169-78.
- 23. Arduini D, Rizzo G. Normal values of pulsatility index from fetal vessels: a cross-sectional study on 1556 healthy fetuses. J Perinat Med 1990;18:165-72.
- 24. Vyas S, Nicolaides KH, Campbell S. Renal artery flow-velocity waveforms in normal and hypoxemic fetuses. Am J Obstet Gynecol 1989;161:168-72.
- 25. Platt JF, Ellis JH, Rubin JM, DiPietro MA, Sedman AB. Intrarenal arterial Doppler sonography in patients with nonobstructive renal disease: correlation of resistive index with biopsy findings. Am J Roentgen 1990;154:1223-7.
Toplam 25 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Kadın Hastalıkları ve Doğum |
| Bölüm | Original Article |
| Yazarlar | |
| Yayımlanma Tarihi | 4 Eylül 2022 |
| Gönderilme Tarihi | 11 Mart 2022 |
| Kabul Tarihi | 21 Haziran 2022 |
| Yayımlandığı Sayı | Yıl 2022 Cilt: 8 Sayı: 5 |
e-ISSN: 2149-3189
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