Gebelik ve Göz: Gebelik Döneminde Göz Hastalıkları Görülme Sıklığı

Aylin Önder Dirican; Emrah Dirican

Klinik Araştırma

Gebelik ve Göz: Gebelik Döneminde Göz Hastalıkları Görülme Sıklığı

Yıl 2024, Cilt: 10 Sayı: 1, 225 - 236

Öz

Amaç: Konya Şehir Hastanesi Göz Kliniğinde muayene edilen gebe hastaların tanı sıklıklarını her üç trimester açısından değerlendirmek.
Yöntem ve Gereçler: Ocak 2022- Ekim 2023 tarihleri arasında Konya Şehir Hastanesi Göz Kliniğinde muayene edilen tüm hastalar sistem üzerinden tarandı. Bu hastalardan 15-45 yaş aralığında olan, eş zamanlı gebelik tanıları olanlar tespit edildi. Hastaların gebelik trimesterleri, göz polikliniğinde aldıkları tanılar ve muayene takvim ayları incelendi.
Bulgular: Belirtilen tarihler arasında KŞGHK muayene olan hasta sayısı 241.512 idi. Bu hastalardan 550 tanesi göz polikliniğinde muayene olduklarında gebeydi ve bu sayı toplam hastaların %0.23’ünü oluşturuyordu. Hastaların %25’i 1. trimester, %38’i 2. trimester ve %36’sı 3. trimesterda idi. Poliklinik başvurularında en sık görülen tanı %41 ile Kuru Göz Hastalığı (KGH), ikinci sırada %36 sıklıkta Refraksiyon Kusuru ve üçüncü sırada %13 ile Konjonktivit vardı. Tüm trimesterlerde en sık görülen tanı olan KGH’nın görülme oranları 1., 2. ve 3. trimesterler için sırası ile %48, %39 ve %37 idi.
Sonuç: Çalışmamızda elde ettiğimiz veriler ışığında gebelikte en sık görülen göz poliklinik başvuru sebebi KGH’dır. Çalışmamızı retrospektif planlandığımız için KGH subtipleri ile ilgili bir araştırma yapılmamıştır. Bundan sonra yapılacak çalışmalarla KGH gibi diğer hastalıkların da ülkemiz için insidansı ve sıkça görülen diğer hastalıklar daha iyi değerlendirilebilecek. Bu hastalıklar için tanı ve tedavi protokolleri oluşturulabilecektir.

Anahtar Kelimeler

gebelik, göz hastalıkları, Kuru göz hastalığı

Etik Beyan

Etik Kurul onayı alınmıştır.

Destekleyen Kurum

Yok

Kaynakça

1. https://www.who.int/standards/classifications/classification-of-diseases
2. Soma-Pillay, P.; Nelson-Piercy, C.; Tolppanen, H.; Mebazaa, A. Physiological changes in pregnancy. Cardiovasc. J. Afr. 2016, 27, 89–94.
3. Kalogeropoulos, D.; Sung, V.C.; Paschopoulos, M.; Moschos, M.M.; Panidis, P.; Kalogeropoulos, C. The physiologic and pathologic effects of pregnancy on the human visual system. J. Obstet. Gynaecol. 2019, 39, 1037–1048.
4. Naderan M. Ocular changes during pregnancy. J Curr Ophthalmol. 2018 Jan 3;30(3):202-210.
5. Bolanca I, Bolanca Z, Kuna K, Vuković A, Tuckar N, Herman R, Grubisić G. Chloasma--the mask of pregnancy. Coll Antropol. 2008 Oct;32 Suppl 2:139-41. PMID: 19140277.
6. Nebbioso M, Regno PD, Gharbiya M, Sacchetti M, Plateroti R, Lambiase A. Analysis of the pathogenic factors and management of Dry eye in ocular surface disorders. Int J Mol Sci 2017;18:1764. 7. Craig JP, Nichols KK, Akpek EK, Caffery B, Dua HS, Joo CK, Liu Z, Nelson JD, Nichols JJ, Tsubota K, Stapleton F. TFOS DEWS II Definition and Classification Report. Ocul Surf. 2017 Jul;15(3):276-283.
8. Asiedu K, Kyei S, Adanusa M, Ephraim RKD, Animful S, Ali-Baya SK, Akorsah B, Sekyere MA. Dry eye, its clinical subtypes and associated factors in healthy pregnancy: A cross-sectional study. PLoS One. 2021 Oct 7;16(10):e0258233
9. Ibraheem WA, Ibraheem AB, Tijani AM, Oladejo S, Adepoju S, Folohunso B. Tear film functions and intraocular pressure changes in pregnancy. Afr J Reprod Health 2015;19(4):118.
10. SchechterJE, PidgeonM, ChangD, FongYC, TrousdaleMD, ChangN. Potentialrole of disrupted lacrimal acinar cells in dry eye during pregnancy. Adv Exp Med Biol 2002; 506:153 –7
11. Nkiru Z N, Stella O, Udeh N, Polycarp U A, Daniel C N, Ifeoma R E. Dry eye disease: A longitudinal study among pregnant women in Enugu, south east, Nigeria. Ocul Surf. 2019 Jul;17(3):458-463.
12. Piekorz, R.P.; Gingras, S.; Hoffmeyer, A.; Ihle, J.N.; Weinstein, Y. Regulation of Progesterone Levels during Pregnancy and Parturition by Signal Transducer and Activator of Transcription 5 and 20α-Hydroxysteroid Dehydrogenase. Mol. Endocrinol. 2005, 19, 431–440
13.Efe YK, Ugurbas SC, Alpay A, Ugurbas SH. The course of corneal and intraocular pressure changes during pregnancy. Can J Ophthalmol J Can d'ophtalmologie. 2012;47(2):150e154.
14. Bilgihan K, Hondur A, Sul S, Ozturk S. Pregnancy-induced progression of keratoconus. Cornea. 2011;30(9):991e994.
15. Mehdizadehkashi K, Chaichian S, Mehdizadehkashi A, et al. Visual acuity changes during pregnancy and postpartum: a cross-sectional study in Iran. J Pregnancy. 2014;2014, 675792
16. Karakucuk Y, Altinkaynak H, Karakuçuk S, Beyoglu A, Çömez A, Demir M. Density of crystalline lens and cornea in different trimesters of pregnancy. Cont Lens Anterior Eye. 2019 Jun;42(3):283-288.
17. Razeghinejad MR. Glaucoma medications in pregnancy. Oman J Ophthalmol. 2018 Sep-Dec;11(3):195-199.
18. Chandrasekaran PR, Madanagopalan VG, Narayanan R. Diabetic retinopathy in pregnancy - A review. Indian J Ophthalmol. 2021 Nov;69(11):3015-3025.
19. Martins TGDS, Schor P, Mendes LGA, Anschütz A, Silva R. Eye diseases during pregnancy: a study with the medical data warehouse in the eye clinic of the Ludwig-Maximilians-Universität München in Munich in Germany. Einstein (Sao Paulo). 2022 May 6;20:eAO6613.
20. https://data.tuik.gov.tr/Bulten/Index?p=Dogum-Istatistikleri-2022-49673
21. Base de Dados Portugal Contemporâneo (PORTADA). Retrato de Portugal: indicadores 2011. Paris: PORDATA [citado 2019 Dez 30]. Disponível em:https://www.pordata.pt/Europa/Idade+m%c3%a9dia+da+m%c3%a3e+a o+nascimento+de+um+filho-2408.
22. Anantharaman D, Radhakrishnan A, Anantharaman V. Subjective Dry Eye Symptoms in Pregnant Women-A SPEED Survey. J Pregnancy. 2023 Jan 4;2023:3421269.
23.Duran M, Güngör İ. The effect of pregnancy on tear osmolarity. Cont Lens Anterior Eye. 2019 Apr;42(2):196-199.
24. Pizzarello LD. Refractive changes in pregnancy. Graefes Arch Clin Exp Ophthalmol. 2003 Jun;241(6):484-8.
25. Mirzajani A, Narooie-Noori F, Amini Vishteh R, Mirsharif SZ, Azampour S, Medhat H, Motahar SS. Changes in Refractive and Optometric Findings During Pregnancy. Med J Islam Repub Iran. 2022 Sep 5;36:102.
26. Wu F, Schallhorn JM, Lowry EA. Refractive status during pregnancy in the United States: results from NH ANES 2005-2008. Graefes Arch Clin Exp Ophthalmol. 2020 Mar;258(3):663-667.
27. Morrison JL, Hodgson LA, Lim LL, Al-Qureshi S. Diabetic retinopathy in pregnancy: a review. Clin Exp Ophthalmol. 2016 May;44(4):321-34.

Pregnancy and The Eye: Frequency of Eye Diseases During Pregnancy

Yıl 2024, Cilt: 10 Sayı: 1, 225 - 236

Aylin Önder Dirican Emrah Dirican

Öz

Aim: To determine the diagnosis frequency of pregnant patients examined at Konya City Hospital Ophthalmology Clinic.
Methods: All patients examined between January 2022 and October 2023 were scanned through the system. Among these patients, those who were between the ages of 15-45 and had simultaneous pregnancy diagnoses were identified. Pregnancy trimesters of the patients, diagnoses they received at the ophthalmology clinic, and examination calendar months were examined.
Results: The number of patients examined at Konya City Hospital Eye Clinic between the specified dates was 241,512. A total of 550 of these patients examined in the ophthalmology clinic were pregnant, and this number constituted 0.23% of all patients. According to trimesters, 25% of patients were in the 1st trimester, 38% were in the 2nd trimester, and 36% were in the 3rd trimester. The most common diagnosis in pregnant women at polyclinic admissions was Dry Eye Disease (DED) with 41%, the second was Refractive Error with 36%, and the third was Conjunctivitis with 13%.
Conclusion: In light of the data obtained in our study, the most common reason for admission to the ophthalmology clinic during pregnancy is DED. Since we planned our study retrospectively, no research was conducted on DED subtypes. With future studies, the incidence of other diseases such as DED and other common diseases in our country will be better evaluated. Diagnostic and treatment protocols can be created for these diseases.

Anahtar Kelimeler

Pregnancy, Eye Diseases, Dry Eye Diseases

Kaynakça

1. https://www.who.int/standards/classifications/classification-of-diseases
2. Soma-Pillay, P.; Nelson-Piercy, C.; Tolppanen, H.; Mebazaa, A. Physiological changes in pregnancy. Cardiovasc. J. Afr. 2016, 27, 89–94.
3. Kalogeropoulos, D.; Sung, V.C.; Paschopoulos, M.; Moschos, M.M.; Panidis, P.; Kalogeropoulos, C. The physiologic and pathologic effects of pregnancy on the human visual system. J. Obstet. Gynaecol. 2019, 39, 1037–1048.
4. Naderan M. Ocular changes during pregnancy. J Curr Ophthalmol. 2018 Jan 3;30(3):202-210.
5. Bolanca I, Bolanca Z, Kuna K, Vuković A, Tuckar N, Herman R, Grubisić G. Chloasma--the mask of pregnancy. Coll Antropol. 2008 Oct;32 Suppl 2:139-41. PMID: 19140277.
6. Nebbioso M, Regno PD, Gharbiya M, Sacchetti M, Plateroti R, Lambiase A. Analysis of the pathogenic factors and management of Dry eye in ocular surface disorders. Int J Mol Sci 2017;18:1764. 7. Craig JP, Nichols KK, Akpek EK, Caffery B, Dua HS, Joo CK, Liu Z, Nelson JD, Nichols JJ, Tsubota K, Stapleton F. TFOS DEWS II Definition and Classification Report. Ocul Surf. 2017 Jul;15(3):276-283.
8. Asiedu K, Kyei S, Adanusa M, Ephraim RKD, Animful S, Ali-Baya SK, Akorsah B, Sekyere MA. Dry eye, its clinical subtypes and associated factors in healthy pregnancy: A cross-sectional study. PLoS One. 2021 Oct 7;16(10):e0258233
9. Ibraheem WA, Ibraheem AB, Tijani AM, Oladejo S, Adepoju S, Folohunso B. Tear film functions and intraocular pressure changes in pregnancy. Afr J Reprod Health 2015;19(4):118.
10. SchechterJE, PidgeonM, ChangD, FongYC, TrousdaleMD, ChangN. Potentialrole of disrupted lacrimal acinar cells in dry eye during pregnancy. Adv Exp Med Biol 2002; 506:153 –7
11. Nkiru Z N, Stella O, Udeh N, Polycarp U A, Daniel C N, Ifeoma R E. Dry eye disease: A longitudinal study among pregnant women in Enugu, south east, Nigeria. Ocul Surf. 2019 Jul;17(3):458-463.
12. Piekorz, R.P.; Gingras, S.; Hoffmeyer, A.; Ihle, J.N.; Weinstein, Y. Regulation of Progesterone Levels during Pregnancy and Parturition by Signal Transducer and Activator of Transcription 5 and 20α-Hydroxysteroid Dehydrogenase. Mol. Endocrinol. 2005, 19, 431–440
13.Efe YK, Ugurbas SC, Alpay A, Ugurbas SH. The course of corneal and intraocular pressure changes during pregnancy. Can J Ophthalmol J Can d'ophtalmologie. 2012;47(2):150e154.
14. Bilgihan K, Hondur A, Sul S, Ozturk S. Pregnancy-induced progression of keratoconus. Cornea. 2011;30(9):991e994.
15. Mehdizadehkashi K, Chaichian S, Mehdizadehkashi A, et al. Visual acuity changes during pregnancy and postpartum: a cross-sectional study in Iran. J Pregnancy. 2014;2014, 675792
16. Karakucuk Y, Altinkaynak H, Karakuçuk S, Beyoglu A, Çömez A, Demir M. Density of crystalline lens and cornea in different trimesters of pregnancy. Cont Lens Anterior Eye. 2019 Jun;42(3):283-288.
17. Razeghinejad MR. Glaucoma medications in pregnancy. Oman J Ophthalmol. 2018 Sep-Dec;11(3):195-199.
18. Chandrasekaran PR, Madanagopalan VG, Narayanan R. Diabetic retinopathy in pregnancy - A review. Indian J Ophthalmol. 2021 Nov;69(11):3015-3025.
19. Martins TGDS, Schor P, Mendes LGA, Anschütz A, Silva R. Eye diseases during pregnancy: a study with the medical data warehouse in the eye clinic of the Ludwig-Maximilians-Universität München in Munich in Germany. Einstein (Sao Paulo). 2022 May 6;20:eAO6613.
20. https://data.tuik.gov.tr/Bulten/Index?p=Dogum-Istatistikleri-2022-49673
21. Base de Dados Portugal Contemporâneo (PORTADA). Retrato de Portugal: indicadores 2011. Paris: PORDATA [citado 2019 Dez 30]. Disponível em:https://www.pordata.pt/Europa/Idade+m%c3%a9dia+da+m%c3%a3e+a o+nascimento+de+um+filho-2408.
22. Anantharaman D, Radhakrishnan A, Anantharaman V. Subjective Dry Eye Symptoms in Pregnant Women-A SPEED Survey. J Pregnancy. 2023 Jan 4;2023:3421269.
23.Duran M, Güngör İ. The effect of pregnancy on tear osmolarity. Cont Lens Anterior Eye. 2019 Apr;42(2):196-199.
24. Pizzarello LD. Refractive changes in pregnancy. Graefes Arch Clin Exp Ophthalmol. 2003 Jun;241(6):484-8.
25. Mirzajani A, Narooie-Noori F, Amini Vishteh R, Mirsharif SZ, Azampour S, Medhat H, Motahar SS. Changes in Refractive and Optometric Findings During Pregnancy. Med J Islam Repub Iran. 2022 Sep 5;36:102.
26. Wu F, Schallhorn JM, Lowry EA. Refractive status during pregnancy in the United States: results from NH ANES 2005-2008. Graefes Arch Clin Exp Ophthalmol. 2020 Mar;258(3):663-667.
27. Morrison JL, Hodgson LA, Lim LL, Al-Qureshi S. Diabetic retinopathy in pregnancy: a review. Clin Exp Ophthalmol. 2016 May;44(4):321-34.

Toplam 26 adet kaynakça vardır.

Ayrıntılar

Birincil Dil	Türkçe
Konular	Göz Hastalıkları, Kadın Hastalıkları ve Doğum
Bölüm	Araştırma Makalesi
Yazarlar	Aylin Önder Dirican Emrah Dirican 0000-0003-1501-7975
Erken Görünüm Tarihi	28 Mart 2024
Yayımlanma Tarihi
Gönderilme Tarihi	25 Mart 2024
Kabul Tarihi	27 Mart 2024
Yayımlandığı Sayı	Yıl 2024 Cilt: 10 Sayı: 1

Kaynak Göster

APA	Önder Dirican, A., & Dirican, E. (2024). Gebelik ve Göz: Gebelik Döneminde Göz Hastalıkları Görülme Sıklığı. International Anatolia Academic Online Journal Health Sciences, 10(1), 225-236.