Objective: Mitral valve
prolapse (MVP) is one of the most frequently seen cardiac disorders. The basic
pathophysiologic mechanism is deterioration in the connective tissue leading to
increased elasticity of mitral leaflets. Elasticity of the aorta which is a
well established predictor of adverse cardiovascular outcomes may also differ
in these patients when alteration in the connective tissue is taken into
account. The aim of this study is to investigate the elastic properties of the
aorta in patients with MVP.
Method: Thirty seven patients with MVP and 38 healthy controls were evaluated in
terms of aortic elastic properties using aortic strain, aortic stiffness index
and aortic distensibility.
Results: Median value for aortic strain was 0.07 (0.0338-0.231) in MVP group and
0.079 (0.0345-0.28) in the control group (p=0.359). Aortic stiffness was
calculated on the basis of aortic strain. The mean value for stiffness index
was 6.87 ± 3.59 and 6.21 ± 2.83 in the MVP and control groups respectively
(p=0.388). Distensibility of the aorta was quantified with a median value of
3286 (1229-12700) in patients with MVP and 3400 (1087-13790) in healthy
subjects (p=0.346). Eventually, when the aortic elastic parameters were
compared (aortic strain, stiffness index and distensibility), no difference was
found between MVP and control groups.
Conclusions: The elastic properties of the aorta do not differ in patients with MVP
when compared to healthy individuals. It will not be accurate to predict long
term cardiovascular outcomes based on elastic properties of the aorta in
patients with MVP.
Birincil Dil | İngilizce |
---|---|
Konular | Sağlık Kurumları Yönetimi |
Bölüm | Medical Science Research Makaleler |
Yazarlar | |
Yayımlanma Tarihi | 30 Haziran 2019 |
Kabul Tarihi | 7 Mayıs 2019 |
Yayımlandığı Sayı | Yıl 2019Cilt: 41 Sayı: 2 |