The Impact of Vitamin D and Acute Phase Proteins in the Diagnosis of Hyperemesis Gravidarum

Dilay Karademir; Nazan Yurtçu

doi:10.7197/cmj.1347700

EN

The Impact of Vitamin D and Acute Phase Proteins in the Diagnosis of Hyperemesis Gravidarum

Abstract

Objective: Hyperemesis gravidarum (HG) has severe and dramatic consequences, and the cause of this severe disease has not yet been determined clearly. It is known that hormonal, metabolic, immunological, and inflammatory agents may be effective in their etiology. Our study aimed to investigate the possible role of vitamin D, Lactate Dehydrogenase (LDH), Procalcitonin (PCT), and C- reactive Protein (CRP) in the etiology of HG. Method: In this retrospective study, between June 1, 2021, and January 1, 2022, 110 pregnant women between the ages of 18 and 35 were admitted to the Obstetrics and Gynecology Polyclinic of the Sivas Cumhuriyet University Faculty of Medicine. Fifty-five patients diagnosed with HG were taken as a study group, and fifty-five healthy pregnant women not diagnosed with HG were taken as a control group. Obstetric data and serum vitamin D, LDH, PCT, and CRP values of pregnant women were detected retrospectively. Results: When the groups with and without HG were compared, although the CRP and LDH levels were high in the HG group, they were not statistically significant (p = 0.084, p = 0.546). Vitamin D and PCT were significantly higher in the HG group than in the control group (p = 0.001, p = 0.047). Conclusion: Our study found that vitamin D and PCT levels were high in pregnant women with HG. Further studies with more participants are needed before these inflammatory markers can be used to diagnose HG.

Keywords

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Sistemleri

Bölüm

Araştırma Makalesi

Yazarlar

Dilay Karademir ^*
0000-0002-9813-4255
Türkiye

Nazan Yurtçu
0000-0003-4725-043X
Türkiye

Yayımlanma Tarihi

30 Eylül 2023

Gönderilme Tarihi

22 Ağustos 2023

Kabul Tarihi

11 Eylül 2023

Yayımlandığı Sayı

Yıl 2023 Cilt: 45 Sayı: 3

DOI

https://doi.org/10.7197/cmj.1347700

IZ

https://izlik.org/JA62HX47ZE

Kaynak Göster

RIS / Bibtex

AMA

1.Karademir D, Yurtçu N. The Impact of Vitamin D and Acute Phase Proteins in the Diagnosis of Hyperemesis Gravidarum. CMJ. 2023;45(3):79-84. doi:10.7197/cmj.1347700

The Impact of Vitamin D and Acute Phase Proteins in the Diagnosis of Hyperemesis Gravidarum

Abstract

Keywords

Öz

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster