Öz
-
Anahtar Kelimeler
Kaynakça
- 1. James JR, Congdon PJ, Truscott J, Horsman A, Arthur R. Osteopenia of prematurity. Arch Dis Child. 1986; 61: 871-876.
- 2. Ardran GM. Bone destruction not demonstrable by radiography. Br J Radiol. 1951; 24: 107-109.
- 3. Szulc P, Seeman E, Delmas PD. Biochemical measurements of bone turnover in children and adolescents. Osteoporos Int. 2000; 11: 281-294.
- 4. Schwartz GJ, Brion LP, Spitzer A. The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents. Pediatr Clin North Am. 1987; 34: 571-590.
- 5. Vesper HW, Audain C, Woolfitt A, et al. Highperformance liquid chromatography method to analyze free and total urinary pyridinoline and deoxypyridinoline. Anal Biochem. 2003; 318: 204-211.
- 6. Frost HM. Perspectives: a proposed general model of the \"mechanostat\" (suggestions from a new skeletalbiologic paradigm). Anat Rec. 1996; 244: 139-147.
- 7. Largo RH, Walli R, Duc G, Fanconi A, Prader A. Evaluation of perinatal growth. Presentation of combined intra- and extrauterine growth standards for weight, length and head circumference. Helv Paediatr Acta. 1980; 35: 419-436.
- 8. Forbes GB. Letter: Calcium accumulation by the human fetus. Pediatrics 1976; 57: 976-977.
- 9. Mora S, Weber G, Bellini A, Bianchi C, Chiumello G. Bone modeling alteration in premature infants. Arch Pediatr Adolesc Med. 1994; 148: 1215-1217.
- 10. Beyers N, Alheit B, Taljaard JF, Hall JM, Hough SF. High turnover osteopenia in preterm babies. Bone 1994; 15: 5-13.
- 11. Crofton PM, Shrivastava A, Wade JC, et al. Bone and collagen markers in preterm infants: relationship with growth and bone mineral content over the first 10 weeks of life. Pediatr Res. 1999; 46: 581-587.
- 12. Seibold-Weiger K, Wollmann HA, Ranke MB, Speer CP. Plasma concentrations of the carboxyterminal propeptide of type I procollagen (PICP) in preterm neonates from birth to term. Pediatr Res. 2000; 48:104- 108.
- 13. Aladangady N, Coen PG, White MP, Rae MD, Beattie TJ. Urinary excretion of calcium and phosphate in preterm infants. Pediatr Nephrol. 2004; 19: 1225-1231.
- 14. Catache M, Leone CR. Role of plasma and urinary calcium and phosphorus measurements in early detection of phosphorus deficiency in very low birthweight infants. Acta Paediatr. 2003; 92: 76-80.
Öz
Amaç: Bu çalışmada prematüre infantlarda kemik döngüsü belirteçlerinin seviyesi ölçülerek büyüme, idrar kalsiyumu ve fosforu ile ilişkisine bakıldı. Yöntem: Enteral beslenmesi yaşamın ilk 5 günü içinde başlanmış 39 prematüre infant ile 20 term infant çalışmaya alındı. Premature infantların doğumda ve 4. haftada boy ve kiloları ölçüldü. Kemik döngüsünün belirteçleri için 4. haftada idrar ve kan örnekleri alındı. Bulgular: Serum ß-CrossLaps, idrar deoxypyridinoline, kalsiyum, tübüler fosfat reabsorbsiyonu (TPR) ve TPR/GFR oranı prematüre infantlarda term infantlara göre istatiksel olarak yüksekti (tüm parametreler için p<0.05). Osteocalcin ile doğum kilosu(r=0.306, P=0.05) ve 4. haftadaki vücut ağırlığı arasında (r=0.307, P=0.047) pozitif korelasyon saptanırken, idrar deoxypyridinoline ile doğum kilosu (r=-0.310, P=0.05), kilo alımı (r=-0.625, P=0.001) ve 4. haftadaki vücut ağırlığı(r=-0.387, P=0.015) arasında negatif korelasyon saptandı. İdrar deoxypyridinoline ile TPR'nin korele olduğu gözlendi (r=0.314, P=0.05). Sonuç: Kilo alımı iyi olmayan prematüre infantların osteopeni yönünden risk altında olduğu düşünüldü. TPR ve idrar kalsiyum atılımın ölçümü prematüre osteopenisini saptamada kullanılabilir. Anahtar Kelimeler: Kemik döngüsü, Büyüme, prematürite, İdrar kalsiyumu
Anahtar Kelimeler
Kaynakça
- 1. James JR, Congdon PJ, Truscott J, Horsman A, Arthur R. Osteopenia of prematurity. Arch Dis Child. 1986; 61: 871-876.
- 2. Ardran GM. Bone destruction not demonstrable by radiography. Br J Radiol. 1951; 24: 107-109.
- 3. Szulc P, Seeman E, Delmas PD. Biochemical measurements of bone turnover in children and adolescents. Osteoporos Int. 2000; 11: 281-294.
- 4. Schwartz GJ, Brion LP, Spitzer A. The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents. Pediatr Clin North Am. 1987; 34: 571-590.
- 5. Vesper HW, Audain C, Woolfitt A, et al. Highperformance liquid chromatography method to analyze free and total urinary pyridinoline and deoxypyridinoline. Anal Biochem. 2003; 318: 204-211.
- 6. Frost HM. Perspectives: a proposed general model of the \"mechanostat\" (suggestions from a new skeletalbiologic paradigm). Anat Rec. 1996; 244: 139-147.
- 7. Largo RH, Walli R, Duc G, Fanconi A, Prader A. Evaluation of perinatal growth. Presentation of combined intra- and extrauterine growth standards for weight, length and head circumference. Helv Paediatr Acta. 1980; 35: 419-436.
- 8. Forbes GB. Letter: Calcium accumulation by the human fetus. Pediatrics 1976; 57: 976-977.
- 9. Mora S, Weber G, Bellini A, Bianchi C, Chiumello G. Bone modeling alteration in premature infants. Arch Pediatr Adolesc Med. 1994; 148: 1215-1217.
- 10. Beyers N, Alheit B, Taljaard JF, Hall JM, Hough SF. High turnover osteopenia in preterm babies. Bone 1994; 15: 5-13.
- 11. Crofton PM, Shrivastava A, Wade JC, et al. Bone and collagen markers in preterm infants: relationship with growth and bone mineral content over the first 10 weeks of life. Pediatr Res. 1999; 46: 581-587.
- 12. Seibold-Weiger K, Wollmann HA, Ranke MB, Speer CP. Plasma concentrations of the carboxyterminal propeptide of type I procollagen (PICP) in preterm neonates from birth to term. Pediatr Res. 2000; 48:104- 108.
- 13. Aladangady N, Coen PG, White MP, Rae MD, Beattie TJ. Urinary excretion of calcium and phosphate in preterm infants. Pediatr Nephrol. 2004; 19: 1225-1231.
- 14. Catache M, Leone CR. Role of plasma and urinary calcium and phosphorus measurements in early detection of phosphorus deficiency in very low birthweight infants. Acta Paediatr. 2003; 92: 76-80.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 24 Haziran 2015 |
| Yayımlandığı Sayı | Yıl 2008 Cilt: 21 Sayı: 2 |