Multiple sequence alignment (MSA) is used to align three or more sequences of DNA, RNA and protein. It is prominent for constructing phylogenetic trees and evolutionary relationships between sequences with regard to similarities and dissimilarities. Variety of multiple sequence alignment tools are available online, each having different methods and parameters to align sequences. In this article three MSA tools; CLUSTALW, SAGA and MAFFT are used for five datasets BALiBASE_R9, DIRMBASE, SABmark and additionally constructed DNABali and ProteinBali for alignment. Result show that for both protein and DNA dataset, MAFFT may be more useful among three of MSA tool used.
Birincil Dil | İngilizce |
---|---|
Konular | Yapısal Biyoloji , Biyokimya ve Hücre Biyolojisi (Diğer) |
Bölüm | Makale |
Yazarlar | |
Yayımlanma Tarihi | 30 Aralık 2021 |
Gönderilme Tarihi | 17 Ağustos 2021 |
Kabul Tarihi | 25 Kasım 2021 |
Yayımlandığı Sayı | Yıl 2021 Cilt: 7 Sayı: 2 |