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Yıl 2012, Cilt: 29 Sayı: 1, 42 - 45, 17.04.2012

Güray Sarp Ramazan Amanvermez Cafer Polat Kenan Erzurumlu Erol Kılıç M. Yavuz Gülbahar

https://doi.org/10.5835/jecm.omu.29.01.011

Öz

Kaynakça

  • Adaş, G., Arikan, S., Kemik, O., Oner, A., Sahip, N., Karatepe, O., 2009. Use of albendazole sulfoxide, albendazole sulfone, and combined solu- tions as scolicidal agents on hydatid cysts (in vitro study).World J. Gastroenterol. 15, 112-116.
  • Aggarwal, A.R., Garg, R.L., 1983. Formalin toxicity in hydatid liver disease. Anaesthesia. 38, 662-665.
  • Bilghiti, J., Benhamou, J.P., Houry, S., 1986.Caustic sclerosing cholangitis. Arch. Surg. 121, 1162-1165.
  • Çaglar, R., Yuzbasıoglu, M.F., Bulbuloglu, E., Gul, M., Ezberci, F., Kale, I.T., 2008. In vitro effectiveness of different chemical agents on scolices of hydatid cysts. J. Invest. Surg. 21, 71-75.
  • Eckert, J., Gemmel, M.A., Soulsby, E.J.I., Matya, Z., 1982. Echinococcosis/hydatidosis, surveillance, prevention and control: fao/unep/who guidelines.Food and agriculture organization of the United Nations.
  • Erzurumlu, K., Tezelman, S., Çevikbaş, U., Eldegez, U., 1990. Sklerozan kolanjit etiyolojisinde Skolosidal solüsyonların etkileri. Ulusal Cerrahi Dergisi. 6, 22-26.
  • Erzurumlu, K., Hokelek, M., Baris, S., Sahin, M., Birinci, A., Amanvermez, R., Tac, K., 1998. Effect of albendazole sulfoxide solution on the scolices and the hepatobiliary system. Eur. Surg. Res. 30, 433-438.
  • Eyüpoğlu, B., Doğanay, M., Reis, E., Yüksel, Y.N., Kulaçoğlu, S., Aydın, K.N., 1999. The effects of scolicidal agents on hepatopancreaticobil- iary system “An experimental study”. Turkish J. Gastroenterol. 10, 280-286.
  • Karavias, D.D., Vagianas, C.E., Kakkos, S.K., Panaqopoulis, C.M., 1996. Peritoneal echinococcosis. World J. Surg. 20, 337-340.
  • Kariv, R., Konikoff, F.M., 2002. Sclerosing cholangitis – primary, secondary and more. I.M.A.J. 4, 1141-1142.
  • Khuroo, M.S., Wani, N.A., Javid, G., Khan, B.A., Yattoo, G.N., Shah, A.H., Jeelani, S.G., 1997. Percutaneus drainage compared with surgery for hepatic hydatid cysts. N. Engl. J. Med. 337, 881-887.
  • Kozak, O., Atak, M., Gülec, B., 2000. The effects of scolicidal solutions to liver and biliar tract. Gülhane Medical Journal. 42, 269-275.
  • Montera, J.V.M., Garcia, J.A., Lafuenta, J.P., 1996. Fat-fluid level in hepatic hydatid cysts: A new sign of rupture into the biliary tree? A.J.R. 167, 91-94.
  • Paksoy, Y., Odev, K., Sahin, M., Arslan, A., Koc, O., 2005. Percutaneous treatment of liver hydatid cysts: Comparision of direct injection of albendazole and hypertonic saline solution. A.J.R. 185, 727-733.
  • Sezer, A., Hatipoglu, A.R., Usta, U., Altun, G., Sut, N., 2010. Effects of intraperitoneal melatonin on caustic sclerosing cholangitis due to scoli- cidal solution in a rat model. Curr. Ther. Res. 71, 118-128.
  • Şahin, M., Eryilmaz, R., Bulbuloglu, E., 2004. The effect of scolicidal agents on liver and biliary tree (experimental study). J. Invest. Surg. 17, 323-326.
  • Taranto, D., Beneduce, F., Vitale, L.M., Loguercio, C., Del Vecchio Blanco, C., 1995. Chemical sclerosing cholangitis after injection of scolicidal solution.Ital. J. Gastroenterol. 27, 78-79.
  • Yetim, I., Erzurumlu, K., Hokelek, M., Barıs, S., Dervisoglu, A., Polat, C., Belet, U., Buyukkarabacak, Y., Guvenli, A., 2005. Results of alcohol and albendazole injections in hepatic hydatidosis: Experimental study. J. Gastroenterol. Hepatol. 20, 1442-1447.

The effects of albendazole-alcohol solution on the hepatobiliary system

Yıl 2012, Cilt: 29 Sayı: 1, 42 - 45, 17.04.2012

Güray Sarp Ramazan Amanvermez Cafer Polat Kenan Erzurumlu Erol Kılıç M. Yavuz Gülbahar

https://doi.org/10.5835/jecm.omu.29.01.011

Öz

Most of the scolicidal agents have some toxic effects on the hepatobiliary system included albendazole. The effects of albendazole in alcohol solution on the hepatobiliary system have been investigated in a rat model. The study was performed with 40 rats divided into four groups (n=10/group), Group I: Alcohol-isotonic saline, Group II: Albendazole-isotonic saline, Group III: Albendazole-alcohol-isotonic saline, Group IV: Isotonic saline. After the application of these solutions to the hepatic duct, blood was taken from all of the rats preoperatively and on the 30th postoperative day. The liver and biliary ducts were resected for histopathological examination. No statistically significant difference was obtained for any of the biochemical parameters studied in preoperative and postoperative period among the groups. The histopathological evaluation of the liver revealed that there were no differences among the groups for portal inflammation, hydropic changes, abscess formation, hemorrhage, and fibrosis (p>0.05). According to findings of the bile duct, mild mucosal hyperplasia was observed in groups I and II, but no significant difference was found among the groups (p>0.05). Albendazole in 2% alcohol solution did not cause more hepatobiliary damage than albendazole alone in isotonic saline application on the 30th day.

Anahtar Kelimeler

Hydatid cyst Albendazole Sclerosing cholangitis Scolicidal agent

Kaynakça

  • Adaş, G., Arikan, S., Kemik, O., Oner, A., Sahip, N., Karatepe, O., 2009. Use of albendazole sulfoxide, albendazole sulfone, and combined solu- tions as scolicidal agents on hydatid cysts (in vitro study).World J. Gastroenterol. 15, 112-116.
  • Aggarwal, A.R., Garg, R.L., 1983. Formalin toxicity in hydatid liver disease. Anaesthesia. 38, 662-665.
  • Bilghiti, J., Benhamou, J.P., Houry, S., 1986.Caustic sclerosing cholangitis. Arch. Surg. 121, 1162-1165.
  • Çaglar, R., Yuzbasıoglu, M.F., Bulbuloglu, E., Gul, M., Ezberci, F., Kale, I.T., 2008. In vitro effectiveness of different chemical agents on scolices of hydatid cysts. J. Invest. Surg. 21, 71-75.
  • Eckert, J., Gemmel, M.A., Soulsby, E.J.I., Matya, Z., 1982. Echinococcosis/hydatidosis, surveillance, prevention and control: fao/unep/who guidelines.Food and agriculture organization of the United Nations.
  • Erzurumlu, K., Tezelman, S., Çevikbaş, U., Eldegez, U., 1990. Sklerozan kolanjit etiyolojisinde Skolosidal solüsyonların etkileri. Ulusal Cerrahi Dergisi. 6, 22-26.
  • Erzurumlu, K., Hokelek, M., Baris, S., Sahin, M., Birinci, A., Amanvermez, R., Tac, K., 1998. Effect of albendazole sulfoxide solution on the scolices and the hepatobiliary system. Eur. Surg. Res. 30, 433-438.
  • Eyüpoğlu, B., Doğanay, M., Reis, E., Yüksel, Y.N., Kulaçoğlu, S., Aydın, K.N., 1999. The effects of scolicidal agents on hepatopancreaticobil- iary system “An experimental study”. Turkish J. Gastroenterol. 10, 280-286.
  • Karavias, D.D., Vagianas, C.E., Kakkos, S.K., Panaqopoulis, C.M., 1996. Peritoneal echinococcosis. World J. Surg. 20, 337-340.
  • Kariv, R., Konikoff, F.M., 2002. Sclerosing cholangitis – primary, secondary and more. I.M.A.J. 4, 1141-1142.
  • Khuroo, M.S., Wani, N.A., Javid, G., Khan, B.A., Yattoo, G.N., Shah, A.H., Jeelani, S.G., 1997. Percutaneus drainage compared with surgery for hepatic hydatid cysts. N. Engl. J. Med. 337, 881-887.
  • Kozak, O., Atak, M., Gülec, B., 2000. The effects of scolicidal solutions to liver and biliar tract. Gülhane Medical Journal. 42, 269-275.
  • Montera, J.V.M., Garcia, J.A., Lafuenta, J.P., 1996. Fat-fluid level in hepatic hydatid cysts: A new sign of rupture into the biliary tree? A.J.R. 167, 91-94.
  • Paksoy, Y., Odev, K., Sahin, M., Arslan, A., Koc, O., 2005. Percutaneous treatment of liver hydatid cysts: Comparision of direct injection of albendazole and hypertonic saline solution. A.J.R. 185, 727-733.
  • Sezer, A., Hatipoglu, A.R., Usta, U., Altun, G., Sut, N., 2010. Effects of intraperitoneal melatonin on caustic sclerosing cholangitis due to scoli- cidal solution in a rat model. Curr. Ther. Res. 71, 118-128.
  • Şahin, M., Eryilmaz, R., Bulbuloglu, E., 2004. The effect of scolicidal agents on liver and biliary tree (experimental study). J. Invest. Surg. 17, 323-326.
  • Taranto, D., Beneduce, F., Vitale, L.M., Loguercio, C., Del Vecchio Blanco, C., 1995. Chemical sclerosing cholangitis after injection of scolicidal solution.Ital. J. Gastroenterol. 27, 78-79.
  • Yetim, I., Erzurumlu, K., Hokelek, M., Barıs, S., Dervisoglu, A., Polat, C., Belet, U., Buyukkarabacak, Y., Guvenli, A., 2005. Results of alcohol and albendazole injections in hepatic hydatidosis: Experimental study. J. Gastroenterol. Hepatol. 20, 1442-1447.
Toplam 18 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Surgery Medical Sciences
Yazarlar

Güray Sarp Bu kişi benim

Ramazan Amanvermez

Cafer Polat

Kenan Erzurumlu

Erol Kılıç

M. Yavuz Gülbahar Bu kişi benim

Yayımlanma Tarihi 17 Nisan 2012
Gönderilme Tarihi 12 Ekim 2011
Yayımlandığı Sayı Yıl 2012 Cilt: 29 Sayı: 1

Kaynak Göster

APA Sarp, G., Amanvermez, R., Polat, C., Erzurumlu, K., vd. (2012). The effects of albendazole-alcohol solution on the hepatobiliary system. Journal of Experimental and Clinical Medicine, 29(1), 42-45. https://doi.org/10.5835/jecm.omu.29.01.011
AMA Sarp G, Amanvermez R, Polat C, Erzurumlu K, Kılıç E, Gülbahar MY. The effects of albendazole-alcohol solution on the hepatobiliary system. J. Exp. Clin. Med. Haziran 2012;29(1):42-45. doi:10.5835/jecm.omu.29.01.011
Chicago Sarp, Güray, Ramazan Amanvermez, Cafer Polat, Kenan Erzurumlu, Erol Kılıç, ve M. Yavuz Gülbahar. “The Effects of Albendazole-Alcohol Solution on the Hepatobiliary System”. Journal of Experimental and Clinical Medicine 29, sy. 1 (Haziran 2012): 42-45. https://doi.org/10.5835/jecm.omu.29.01.011.
EndNote Sarp G, Amanvermez R, Polat C, Erzurumlu K, Kılıç E, Gülbahar MY (01 Haziran 2012) The effects of albendazole-alcohol solution on the hepatobiliary system. Journal of Experimental and Clinical Medicine 29 1 42–45.
IEEE G. Sarp, R. Amanvermez, C. Polat, K. Erzurumlu, E. Kılıç, ve M. Y. Gülbahar, “The effects of albendazole-alcohol solution on the hepatobiliary system”, J. Exp. Clin. Med., c. 29, sy. 1, ss. 42–45, 2012, doi: 10.5835/jecm.omu.29.01.011.
ISNAD Sarp, Güray vd. “The Effects of Albendazole-Alcohol Solution on the Hepatobiliary System”. Journal of Experimental and Clinical Medicine 29/1 (Haziran 2012), 42-45. https://doi.org/10.5835/jecm.omu.29.01.011.
JAMA Sarp G, Amanvermez R, Polat C, Erzurumlu K, Kılıç E, Gülbahar MY. The effects of albendazole-alcohol solution on the hepatobiliary system. J. Exp. Clin. Med. 2012;29:42–45.
MLA Sarp, Güray vd. “The Effects of Albendazole-Alcohol Solution on the Hepatobiliary System”. Journal of Experimental and Clinical Medicine, c. 29, sy. 1, 2012, ss. 42-45, doi:10.5835/jecm.omu.29.01.011.
Vancouver Sarp G, Amanvermez R, Polat C, Erzurumlu K, Kılıç E, Gülbahar MY. The effects of albendazole-alcohol solution on the hepatobiliary system. J. Exp. Clin. Med. 2012;29(1):42-5.
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