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Yıl 2013, Cilt: 30 Sayı: 4, 291 - 294, 04.02.2014

Erçin Çelikel Sefa Kurt Emrah Töz Azra Arıcı Yurtkul Tutku Gürbüz Abdullah Taşyurt

https://doi.org/10.5835/jecm.omu.30.04.002

Öz

Kaynakça

  • Bath, P.M., Butterworth, R.J., 1996. Platelet size: Measurement, physiology and vascular disease.Blood Coagul. Fibrin. 7, 157-161.
  • Crowther, C.A., Hiller, J.E., Moss, J.R., McPhee, A.J., Jeffries, W.S., Robinson, J.S., 2005. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N. Engl. J. Med. 352, 2477-2486.
  • Demirtunç, R., Duman, D., Basar, M., Bilgin, M., Garip, T., 2009.The relation between glycemic control and trombosit activity in type 2 diabetes mellitus.J Diabetes Sci. 23, 89-94.
  • Dundar, O., Yoruk, P., Tutuncu, L., Erikci, A.A., Muhcu, M., Ergur A.R., Atay, V., Mungen, E., 2008. Longitudinal study of platelet size changes in gestation and predictive power of elevated MPV in development of pre-eclampsi Prenat Diagn. 28, 1052-1056.
  • Çoban, E., Bostan, F., Özdoğan, M., 2006. The mean platelet volume in subjects with impaired fasting glucose. Plateletes. 17, 67-69.
  • Erikçi, A.A., Muhçu, M., Dündar, O., Öztürk, A., 2008. Could mean platelet volume be a predictive marker for gestational diabetes mellitus? Hematology. 131, 46-48.
  • Harris, S.B., Caulfield, L.E., Sugamori, M.E., Whalen, E.A., Henning, B., 1997.The epidemiology of diabetes in pregnant Native Canadians. A risk profile. Diabetes Care. 20, 422-1425.
  • Hekimsoy, Z., Payzin, B., Örnek, T., Kandoğan, G., 2004. Mean trombosit volume in Type 2 Diabetic patients. J. Diabetes Complications. 18, 173-176.
  • Jagroop, I.A., Mikhailidis, D.P., 2001. Doxazosin, an alpha1-adrenoceptor antagonist, inhibits serotonin-induced shape change in human trom- bosits. J. Hum. Hypertens. 15, 203-207.
  • Jirapinyo, M., Puavilai, G., Chanprasertyotin, S., Tangtrakul, S., 1993. Predictive value of 1 hour 50 g oral glucose load screening test for ges- tational diabetes mellitus compared pregnant women. Asia Oceania J. Obstet. Gynaecol. 19, 7-12.
  • Mazze, R.S., Krogh, C.L., 1992. Gestational diabetes mellitus: Now is the time for detection and treatment. Mayo. Clin. Proc. 67, 995-1002.
  • Papanas, N., Symeonidis, G., Maltezos, E., Mavridis, G., Karavageli, E.,Vosnakidis, T., Lakasas, G., 2004.Mean trombosit volume in patients with type 2 diabetes mellitus . Trombosits. 15, 475-478.
  • Park, Y., Schoene, N., Haris, W., 2002. Mean trombosit volume as an indicator of trombosit activation: Methodological issues. Trombosits. 13, 301-306.
  • Piazze, J., Gioia, S., Maranghi, L., Anceschi, M., 2006.Mean platelet and red blood cell volume measurements to estimate the severity of hyper- tension in pregnancy. J Perinat. Med. 343, 246-7.
  • Sharp, P.C., Trinick T., 1993. Mean trombosit volume in diabetes mellitus.Q.J.M. 86, 739-742.
  • Yogev, Y., Visser, G.H., 2009. Obesity, gestational diabetes and pregnancy outcome.Semin Fetal Neonatal Med. 14, 77-84.

Mean platelet volume in diagnosis of gestational diabetes

Yıl 2013, Cilt: 30 Sayı: 4, 291 - 294, 04.02.2014

Erçin Çelikel Sefa Kurt Emrah Töz Azra Arıcı Yurtkul Tutku Gürbüz Abdullah Taşyurt

https://doi.org/10.5835/jecm.omu.30.04.002

Öz

Gestational diabetes mellitus (GDM) prevalence is within range of 1-14%, varying relative to the countries and ethnic groups. By many studies, mean platelet volume (MPV) has been shown to be higher in GDM and Type II diabetes mellitus patients. Our aim is to evaluate the sensitivity and specificity of MPV in GDM screening. The study population was consisted of pregnant women aged above 18 years with a singleton pregnancy at 24 to 28 weeks of gestation. Three hundred patients complying with the study criteria were split into 3 groups as follows: Group 1, 219 pregnant patients with normal 50g oral glucose tolerance test (OGTT) result; Group 2, 23 pregnant patients diagnosed with impaired glucose tolerance based on the OGTT result; and Group 3, 58 pregnant patients diagnosed with GDM. MPV measurement was started with collecting 2 ml blood samples into K3 Etilendiamintetraasetikasit (EDTA) tubes from each patient. The statistical analyses were done with statistical package for the social sciences (SPSS) 20.0 package program. In our study, the optimal cut-off MPV value for GDM prediction was >8.8 fL. The specificity and negative predictive value of MPV at >8,8 fL were 75.9% and 38.9%, respectively. GDM patients may exhibit significant changes in MPV and hemoglobin A1c (HbA1c) values. Future randomized studies will be helpful in developing a MPV-related diagnostic test, adjusting the treatment, predicting the complications, and taking preventive measures in GDM patients.

Anahtar Kelimeler

Diagnostic test Gestational diabetes mellitus Impaired glucose tolerance Mean platelet volume

Kaynakça

  • Bath, P.M., Butterworth, R.J., 1996. Platelet size: Measurement, physiology and vascular disease.Blood Coagul. Fibrin. 7, 157-161.
  • Crowther, C.A., Hiller, J.E., Moss, J.R., McPhee, A.J., Jeffries, W.S., Robinson, J.S., 2005. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N. Engl. J. Med. 352, 2477-2486.
  • Demirtunç, R., Duman, D., Basar, M., Bilgin, M., Garip, T., 2009.The relation between glycemic control and trombosit activity in type 2 diabetes mellitus.J Diabetes Sci. 23, 89-94.
  • Dundar, O., Yoruk, P., Tutuncu, L., Erikci, A.A., Muhcu, M., Ergur A.R., Atay, V., Mungen, E., 2008. Longitudinal study of platelet size changes in gestation and predictive power of elevated MPV in development of pre-eclampsi Prenat Diagn. 28, 1052-1056.
  • Çoban, E., Bostan, F., Özdoğan, M., 2006. The mean platelet volume in subjects with impaired fasting glucose. Plateletes. 17, 67-69.
  • Erikçi, A.A., Muhçu, M., Dündar, O., Öztürk, A., 2008. Could mean platelet volume be a predictive marker for gestational diabetes mellitus? Hematology. 131, 46-48.
  • Harris, S.B., Caulfield, L.E., Sugamori, M.E., Whalen, E.A., Henning, B., 1997.The epidemiology of diabetes in pregnant Native Canadians. A risk profile. Diabetes Care. 20, 422-1425.
  • Hekimsoy, Z., Payzin, B., Örnek, T., Kandoğan, G., 2004. Mean trombosit volume in Type 2 Diabetic patients. J. Diabetes Complications. 18, 173-176.
  • Jagroop, I.A., Mikhailidis, D.P., 2001. Doxazosin, an alpha1-adrenoceptor antagonist, inhibits serotonin-induced shape change in human trom- bosits. J. Hum. Hypertens. 15, 203-207.
  • Jirapinyo, M., Puavilai, G., Chanprasertyotin, S., Tangtrakul, S., 1993. Predictive value of 1 hour 50 g oral glucose load screening test for ges- tational diabetes mellitus compared pregnant women. Asia Oceania J. Obstet. Gynaecol. 19, 7-12.
  • Mazze, R.S., Krogh, C.L., 1992. Gestational diabetes mellitus: Now is the time for detection and treatment. Mayo. Clin. Proc. 67, 995-1002.
  • Papanas, N., Symeonidis, G., Maltezos, E., Mavridis, G., Karavageli, E.,Vosnakidis, T., Lakasas, G., 2004.Mean trombosit volume in patients with type 2 diabetes mellitus . Trombosits. 15, 475-478.
  • Park, Y., Schoene, N., Haris, W., 2002. Mean trombosit volume as an indicator of trombosit activation: Methodological issues. Trombosits. 13, 301-306.
  • Piazze, J., Gioia, S., Maranghi, L., Anceschi, M., 2006.Mean platelet and red blood cell volume measurements to estimate the severity of hyper- tension in pregnancy. J Perinat. Med. 343, 246-7.
  • Sharp, P.C., Trinick T., 1993. Mean trombosit volume in diabetes mellitus.Q.J.M. 86, 739-742.
  • Yogev, Y., Visser, G.H., 2009. Obesity, gestational diabetes and pregnancy outcome.Semin Fetal Neonatal Med. 14, 77-84.
Toplam 16 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Surgery Medical Sciences
Yazarlar

Erçin Çelikel Bu kişi benim

Sefa Kurt

Emrah Töz

Azra Arıcı Yurtkul Bu kişi benim

Tutku Gürbüz Bu kişi benim

Abdullah Taşyurt Bu kişi benim

Yayımlanma Tarihi 4 Şubat 2014
Gönderilme Tarihi 26 Haziran 2013
Yayımlandığı Sayı Yıl 2013 Cilt: 30 Sayı: 4

Kaynak Göster

APA Çelikel, E., Kurt, S., Töz, E., Arıcı Yurtkul, A., vd. (2014). Mean platelet volume in diagnosis of gestational diabetes. Journal of Experimental and Clinical Medicine, 30(4), 291-294. https://doi.org/10.5835/jecm.omu.30.04.002
AMA Çelikel E, Kurt S, Töz E, Arıcı Yurtkul A, Gürbüz T, Taşyurt A. Mean platelet volume in diagnosis of gestational diabetes. J. Exp. Clin. Med. Şubat 2014;30(4):291-294. doi:10.5835/jecm.omu.30.04.002
Chicago Çelikel, Erçin, Sefa Kurt, Emrah Töz, Azra Arıcı Yurtkul, Tutku Gürbüz, ve Abdullah Taşyurt. “Mean Platelet Volume in Diagnosis of Gestational Diabetes”. Journal of Experimental and Clinical Medicine 30, sy. 4 (Şubat 2014): 291-94. https://doi.org/10.5835/jecm.omu.30.04.002.
EndNote Çelikel E, Kurt S, Töz E, Arıcı Yurtkul A, Gürbüz T, Taşyurt A (01 Şubat 2014) Mean platelet volume in diagnosis of gestational diabetes. Journal of Experimental and Clinical Medicine 30 4 291–294.
IEEE E. Çelikel, S. Kurt, E. Töz, A. Arıcı Yurtkul, T. Gürbüz, ve A. Taşyurt, “Mean platelet volume in diagnosis of gestational diabetes”, J. Exp. Clin. Med., c. 30, sy. 4, ss. 291–294, 2014, doi: 10.5835/jecm.omu.30.04.002.
ISNAD Çelikel, Erçin vd. “Mean Platelet Volume in Diagnosis of Gestational Diabetes”. Journal of Experimental and Clinical Medicine 30/4 (Şubat 2014), 291-294. https://doi.org/10.5835/jecm.omu.30.04.002.
JAMA Çelikel E, Kurt S, Töz E, Arıcı Yurtkul A, Gürbüz T, Taşyurt A. Mean platelet volume in diagnosis of gestational diabetes. J. Exp. Clin. Med. 2014;30:291–294.
MLA Çelikel, Erçin vd. “Mean Platelet Volume in Diagnosis of Gestational Diabetes”. Journal of Experimental and Clinical Medicine, c. 30, sy. 4, 2014, ss. 291-4, doi:10.5835/jecm.omu.30.04.002.
Vancouver Çelikel E, Kurt S, Töz E, Arıcı Yurtkul A, Gürbüz T, Taşyurt A. Mean platelet volume in diagnosis of gestational diabetes. J. Exp. Clin. Med. 2014;30(4):291-4.
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